YAMAGUCHI Takeru

Researcher Profile & Settings

Research

Overview of research:
The aim of our study is to investigate the mechanisms of carcinogenesis using animal models (chemical carcinogenesis, genetically modified animals), and techniqus of histopathology (histological analysis, immunohistochemistry, fluorescence microscope, laser-captured microdissection) and molecular biology (real-time RT-PCR、chromatin immunoprecipitation, methylation specific PCR, Western blotting).

Education

• Gifu University

Research Activities

Published Papers

• Colorectal carcinogenesis and suppression of tumor development by inhibition of enzymes and molecular targets, Y.Yasui, M.Kim, T.Oyama, T.Tanaka, Current Enzyme Inhibition., 5:1-26, 2009
• Melatonin suppresses AOM/DSS-induced large bowel oncogenesis in rats, T.Tanaka, Y.Yasui, M.Tanaka, T.Tanaka, T.Oyama, KM Wahidur Rahman, Chemico-biological interactions., 177:128-136, 2009
• Breast cancer chemoprevention: current perspectives, T.Oyama, Y.Yasui, T.Tanaka, Current Enzyme Inhibition., 5:198-208, 2009
• Zerumbone, a tropical ginger sesquiterpene, inhibits colon and lung carcinogenesis in mice, (M.Kim), S.Miyamoto, Y.Yasui, T.Oyama, A.Murakami, T.Tanaka, Int. J. Cancer., 124:264-271, 2009
• Citrus compounds inhibit inflammation- and obesity-related colon carcinogenesis in mice, T.Tanaka, Y.Yasui, R.Ishigamori-Suzuki, T.Oyama, Nutrition and cancer., 60(Suppl.1):70-80, 2008
• Preclinical assays for identifying cancer chemopreventive phytochemicals, T.Oyama, Y.Yasui, S.Sugie, T.Tanaka, Scholarly Research Exchange., Article ID 475963・doi: 10.3814, 2009
• Dietary tricin suppresses inflammation-related colon carcinogenesis in male Crj: CD-1 mice, T.Oyama, Y.Yasui, S.Sugie, M.Koketsu, K.Watanabe, T.Tanaka, Cancer prevention research (Philadelphia, Pa.), 2:1031-1038, 2009
• A case of lymphomatous pleural effusion from angioimmunoblastic T‐cell lymphoma: The methodology of cell transfer technique and immunocytochemistry on an inadequate cytology specimen can potentially guide us to the correct diagnosis , Kinue Takebayashi, Rie Kadoguchi, Akihiro Shioya, Takeru Oyama, Sohsuke Yamada, Cytopathology, 35:145-148, Sep. 2023
  DOI:10.1111/cyt.13299
• The combination of the low immunohistochemical expression of peroxiredoxin 4 and perilipin 2 predicts longer survival in pancreatic ductal adenocarcinoma with peroxiredoxin 4 possibly playing a main role, Jia Han, Tohru Itoh, Akihiro Shioya, Masaru Sakurai, Takeru Oyama, Motona Kumagai, Hiroyuki Takamura , Masashi Okuro, Tsuyoshi Mukai, Hidekazu Kitakata, Masaru Inagaki, Michiyo Higashi, Xin Guo, Sohsuke Yamada, HISTOLOGY AND HISTOPATHOLOGY, 38:1415-1427, Dec. 2023
  DOI:10.14670/HH-18-666
• Periarterial or perivenous invasion is an independent indicator of lymph node metastasis in invasive breast carcinoma of no special type, Akihiro Shioya, Mao Takata, Motona Kumagai, Daisuke Hoshi, Jia Han, Takeru Oyama, Yusuke Haba, Emi Morioka, Masafumi Inokuchi, Masakuni Noguchi, Sohsuke Yamada, Pathology - Research and Practice, 260:155407, Jun. 2024
• VEGFA locus amplification potentially predicts a favorable prognosis in gastric adenocarcinoma., Takeru Oyama, Toshiyuki Yamamoto, Ritsuko Nakamura, Jia Han, Yao Liu, Akihiro Shioya, Akishi Ooi, Daichi Maeda, Sohsuke Yamada, Pathology - Research and Practice, 260:155441, Jul. 2024
• Unique Cytopathological Findings of a Mucinous Myoepithelioma Showing a Mucous Globule and a "Sieve-Like" Structure, Takeru Oyama, Akihiro Shioya, Hiroko Ikeda, Daichi Maeda, Sohsuke Yamada, Cureus, 16:e67697, Aug. 2024
• The immunohistochemical combination of low SGLT2 expression and high PRDX4 expression independently predicts shortened survival in patients undergoing surgical resection for hepatoblastoma, Yao Liu, Jia Han, Akihiro Shioya, Yang-Xian Zhang, Vu Anh Dung, Takeru Oyama, Xin Guo, Qian Yang, Tohru Ito, Sohsuke Yamada, Diagnostic Pathology, 20:2, Jan. 2025