Intracellular toxic advanced glycation end-products promote the production of reactive oxygen species in HepG2 cells, Sakasai-Sakai A, Takata T, Takeuchi M, International Journal of Molecular Sciences, 21:4861, 2020年07月
Nutritional conditions and oxygen concentration affect spontaneous occurrence of homologous recombination events but not spontaneous mutagenesis in Escherichia coli, (Lan Anh Thi Le), Phooi Yee Chang, Sayaka Ando, Thomas M. Conrad, Shohei Nunose, Akiko Sakai, Haruka Uefune, Asako Furukohri, Masahiro Tatsumi Akiyama, Hisaji Maki, Genes & Genetic Systems, 95:85-93, 2020年05月
第3のグリコーゲン代謝産物1,5-アンヒドロ-D-フルクトース(1,5-AF)の謎を探る, 逆井(坂井)亜紀子, 髙田尊信, 鈴木宏一, 丸山征郎, 田中賢治, 本宮善恢, 竹内正義, 日本未病学会雑誌, 26:67-72, 2020年01月
Immunological evidence for in vivo production of novel advanced glycation end-products from 1,5-anhydro-D-fructose, a glycogen metabolite, Sakasai-Sakai Akiko, Takata Takanobu, Suzuki Hirokazu, Maruyama Ikuro, Motomiya Yoshihiro, Takeuchi Masayoshi, Scientific Reports, 9:10194, 2019年07月
Evidence for toxic advanced glycation end-products generated in the normal rat liver, Takata Takanobu, Sakasai-Sakai Akiko, Takino Jun-ichi, Takeuchi Masayoshi, Nutrients, 11:1612, 2019年07月
The relevance of toxic AGEs (TAGE) cytotoxicity to NASH pathogenesis: A mini-review, Sakasai-Sakai Akiko, Takata Takanobu, Takino Jun-Ichi, Takeuchi Masayoshi, Nutrients, 11:462, 2019年02月
Intracellular toxic advanced glycation end-products in cardiomyocytes may cause cardiovascular disease, Takata Takanobu, Sakasai-Sakai Akiko, Ueda Tadashi, Takeuchi Masayoshi, Scientific Reports, 9:2121, 2019年02月
生活習慣病の発症・進展における新規バイオマーカーToxic AGEs (TAGE), 高田尊信, 逆井(坂井)亜紀子, 竹内正義, 日本未病システム学会雑誌, 24:27-33, 2018年08月
NAFLDとALDの発症・進展におけるToxic AGEs(TAGE)病因説, 逆井(坂井)亜紀子, 瀧野純一, 福村敦, 高田尊信, 堤幹宏, 竹内正義, 日本未病システム学会雑誌, 24:19-25, 2018年03月
Impact of intracellular glyceraldehyde-derived advanced glycation end-products on human hepatocyte cell death, Akiko Sakasai-Sakai, Takanobu Takata, Jun-ichi Takino, Masayoshi Takeuchi, SCIENTIFIC REPORTS, 7:1, 2017年10月
Generation of glyceraldehyde-derived advanced glycation end-products in pancreatic cancer cells and the potential of tumor promotion, Takanobu Takata, Tadashi Ueda, Akiko Sakasai-Sakai, Masayoshi Takeuchi, World Journal of Gastroenterology, 23:4910-4919, 2017年07月
Toxic AGE (TAGE) Theory for the Pathophysiology of the Onset/Progression of NAFLD and ALD, Masayoshi Takeuchi, Jun-ichi Takino, Akiko Sakasai-Sakai, Takanobu Takata, Mikihiro Tsutsumi, Nutrients, 9:634, 2017年06月
Gene Expression Changes Associated with the Loss of Heterogeneous Nuclear Ribonucleoprotein M Function, (Jun-ichi Takino), Kentaro Nagamine, Mikoto Suzuki, Akiko Sakasai-Sakai, Masayoshi Takeuchi, Takamitsu Hori, American Journal of Molecular Biology, 7:87-98, 2017年04月
非アルコール性脂肪性肝疾患(NAFLD)の発症・進展におけるToxic AGEs(TAGE)の関与, 竹内正義, 逆井亜紀子, 高田尊信, 上田忠司, 瀧野純一, 日本未病システム学会雑誌, 23:20-30, 2017年
Contribution of the toxic advanced glycation end-products-receptor axis in nonalcoholic steatohepatitis-related hepatocellular carcinoma, (J.Takino), K.Nagamine, T.Hori, A.Sakasai-Sakai, M.Takeuchi, World Journal of Hepatology, 7:2459-2469, 2015年08月
Toxic AGEs (TAGE) theory in the pathogenesis of NAFLD and ALD, M.Takeuchi, A.Sakasai-Sakai, J.Takino, T.Takata, T.Ueda, M.Tsutsumi, International Journal of Diabetes and Clinical Researsh, 2:1-5, 2015年07月
不妊治療バイオマーカーとしてのToxic AGEs(TAGE)の有用性, 逆井(坂井)亜紀子, 神野正雄, 竹内正義, 日本未病システム学会雑誌, 21:93, 2015年03月
生活習慣病の発症・進展におけるToxic AGEs (TAGE) の関与 -新たな予防戦略- ~食事性AGEsおよび糖毒性の真実~, 竹内正義, 瀧野純一, 逆井(坂井)亜紀子, 高田尊信, 上田忠司, 金沢医科大学雑誌, 40:95-103, 2015年
Serum levels of toxic AGEs (TAGE) may be a promising novel biomarker in development and progression of NASH., M.Takeuchi, A.Sakasai-Sakai, T.Takata, T.Ueda, J.Takino, M.Tsutsumi, H.Hyogo, S.Yamagishi, Medical Hypotheses, 84:490-493, 2015年
Involvement of the TAGE-RAGE system in non-alcoholic steatohepatitis: Novel treatment strategies., M.Takeuchi, J.Takino, A.Sakasai-Sakai, T.Takata, T.Ueda, M.Tsutsumi, H.Hyogo, S.Yamagishi, World journal of hepatology [electronic resource], 6:880-893, 2014年12月
PARP and CSB modulate the processing of transcription-mediated DNA strand breaks., A.Sakai, R.Sakasai, Y.Kakeji, H.Kitao, Y.Maehara, Genes & genetic systems., 87:265-272, 2012年12月
CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication., R.Sakasai, A.Sakai, M.Iimori M, Y.Kakeji, H.Kitao, Y.Maehara, Genes to cells : devoted to molecular & cellular mechanisms, 17:962-970, 2012年12月
RecFOR and RecOR as distinct RecA loading pathways., A.Sakai, M.M.Cox, Journal of biochemistry., 284:3264-3272, 2009年01月
SSB limits RecOR binding onto single strand DNA., (M.D.Hobbs), A.Sakai, M.M.Cox, Journal of biochemistry., 282:11058-11067, 2007年04月
Roles of RecA protein in spontaneous mutagenesis in Escherichia coli., (S.Kanie), K.Horibata, M.Kawano, A.Isogawa, A.Sakai, N.Matsuo, M.Nakanishi, K.Hasegawa, K.Yoshiyama, H.Maki, Genes & genetic systems., 82:99-108, 2007年04月
Impact of reactive oxygen species on spontaneous mutagenesis in Escherichia coli., A.Sakai, M.Nakanishi, K.Yoshiyama, H.Maki, Genes to cells, 11:767-787, 2006年07月
Impact of intracellular toxic advanced glycation end-products (TAGE) on murine myoblast cell death, Takata Takanobu, Sakasai-Sakai Akiko, Takeuchi Masayoshi, Diabetology & Metabolic Syndrome, 12:54, 2020年06月
Accumulation of toxic advanced glycation end-products induces cytotoxicity and inflammation in hepatocyte-like cells differentiated from human induced pluripotent stem cells., (Kikuchi C), Sakasai-Sakai A, Okimura R, Tanaka H, Takata T, Takeuchi M, Matsunaga T, Biol. Pharm. Bull., 44:1399-1402, 2021年10月
Serum levels of 1,5-anhydroglucitol and 1,5-anhydrofructose-derived advanced glycation end products in patients undergoing hemodialysis., (Tanaka K), Sakasai-Sakai A, Motomiya Y, Yoneda T, Takeuchi M, Diabetol. Metab. Syndr., 13:85, 2021年08月
Intracellular toxic AGEs (TAGE) triggers numerous types of cell damage., Takeuchi M, Sakasai-Sakai A, Takata T, Takino J, Koriyama Y, Furukawa A, Kikuchi C, Nagamine K, Hori T, Matsunaga T, Biomolecules, 11:387, 2021年03月
Suppression of hepatic stellate cell death by toxic advanced glycation end-products., (Takino J), Sato T, Nagamine K, Sakasai-Sakai A, Takeuchi M, Hori T, Biol. Pharm. Bull., 44:112-117, 2021年01月
NAFLD/ALDとToxic AGEs (TAGE), 逆井(坂井)亜紀子、竹内正義, 糖尿病・内分泌代謝科, 52:50-57, 2021年01月
Intracellular Toxic Advanced Glycation End-Products in 1.4E7 Cell Line Induce Death with Reduction of Mirotubule-Associated Protein 1 Light Chain 3 and p62, Takanobu Takata, Akiko Sakasai-Sakai, Masayoshi Takeuch, Nutrients, 14:332, 2022年01月
Intracellular Toxic Advanced Glycation End-Products May Induce Cell Death and Suppress Cardiac Fibroblasts, Takanobu Takata, Akiko Sakasai-Sakai, Masayoshi Takeuchi, Metabolites, 12:615, 2022年07月
Effects of Toxic AGEs (TAGE) on Human Health, Masayoshi Takeuchi, Akiko Sakasai-Sakai, Takanobu Takata, Cells, 11:2178, 2022年07月
The association between accumulation of toxic advanced glycation end-products and cytotoxic effect in MC3T3-E1 cells., Sakasai-Sakai A, Takata T, Takeuchi M, Nutrients, 14:990, 2022年02月
Involvement of intercellular TAGE and the TAGE-RAGE-ROS axis in the onset and progression of NAFLD/NASH., Sakasai-Sakai A, Takeda K, Takeuchi M, Antioxidants, 12:748, 2023年03月
Toxic AGEs (TAGE)と健康:I. 細胞障害因子としてのTAGE, 坂井(逆井)亜紀子、竹田健史、竹内正義, 金沢医科大学雑誌, 48:1-11, 2023年03月
Toxic AGEs (TAGE) と健康:II. 生活習慣病予測マーカーとしての TAGE, 竹内正義、竹田健史、坂井(逆井)亜紀子, 金沢医科大学雑誌, 48:12-21, 2023年03月
A Novel Approach: Investigating the Intracellular Clearance Mechanism of Glyceraldehyde-Derived Advanced Glycation End-Products Using the Artificial Checkpoint Kinase 1 d270KD Mutant as a Substrate Model, Kenji Takeda, Akiko Sakai-Sakasai, Kouji Kajinami, Masayoshi Takeuchi, Cells, 12:2838-2838, 2023年12月
Structures of Toxic Advanced Glycation End-Products Derived from Glyceraldehyde, A Sugar Metabolite, Akiko Sakai-Sakasai, Kenji Takeda, Hirokazu Suzuki, Masayoshi Takeuchi, Biomolecules, 14:202-202, 2024年02月