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神田 享勉 カンダ ツギヤス

所属部署名地域医療学
職名教授
 
 

研究者基本情報

研究

    研究の概要:
    心不全、心筋症を含む心血管系に関するサイトカインの治療応用が研究の主体である。今までにインターロイキン6、8、10、TNF-α、レプチン、アディポネクチンなどの解析をおこなった。研究の動物モデルはマウスウイルス性心筋炎、ラット心筋梗塞、マウス糖尿病などである。

専門分野

  • 循環器内科学
    心臓病学
  • 内科学一般
    総合診療学

学位

  • 医学博士

所属学協会

  • - 2015年日本内科学会北陸支部 評議員
  • - 2015年日本肥満学会 評議員
  • - 2015年北関東医学会 評議員

研究活動情報

論文

  • The Impact of Tofogliflozin on Physiological and Hormonal Function, Serum Electrolytes, and Cardiac Diastolic Function in Elderly Japanese Patients with Type 2 Diabetes MellitusToshihiro Higashikawa, Tomohiko Ito, Takurou Mizuno, Keiichiro Ishigami, Kengo Kuroki, Naoto Maekawa, Daisuke Usuda, Toshihide Izumida, Shinya Yamada, Ryusho Sangen, Kazu Hamada, Jun Kiyosawa, Atsushi Saito, Masaharu Iguchi, Yuji Kasamaki, Takeshi Nakahashi, Akihiro Fukuda, Hitoshi Saito, Tsugiyasu Kanda, Masashi OkuroActa Medica Okayama76:705-7132022年12月
  • A new predictive tool consolidating CURB-65 with procalcitonin and albumin to assess short-term mortality in hospitalized elderly patients with infectious disease: A retrospective study of a patient cohortToshihiro Higashikawa, Tomohiko Ito, Takuro Mizuno, Keiichirou Ishigami, Kengo Kuroki, Naoto Maekawa, Daisuke Usuda, Shinichiro Nakao, Kazu Hamada, Susumu Takagi, Nao Terada, Kento Takeshima, Shinya Yamada, Ryusho Sangen, Toshihide Izumida, Jun Kiyosawa, Atsushi Saito, Masaharu Iguchi, Hiroyuki Wato, Takeshi Nakahashi, Yuji Kasamaki, Akihiro Fukuda, Tsugiyasu Kanda, Masashi OkuroMedicine101:e31614.2022年11月
  • Postoperative Urinary Retention in Japanese Elderly Males with a Femoral Neck or Trochanteric FractureToshihiro Higashikawa, Kenji Shigemoto, Kenichi Goshima, Shintarou Iwai, Manabu Moriyama, Daisuke Usuda, Masahiro Hangyou, Hiromi Inujima, Kakeru Nozaki, Miyako Yamaguchi, Kimiko Usuda, Takeshi Nakahashi, Tadami Matsumoto, Shigeki Takashima, Tsugiyasu Kanda, Takeshi Horii, Masashi Okuro, Takeshi SawaguchiActa Medica Okayama76:409-4142022年08月
  • Effects of tofogliflozin on adrenocorticotropic hormone, renin and aldosterone, and cortisol levels in elderly patients with diabetes mellitus: A retrospective study of a patient cohortToshihiro Higashikawa, Tomohiko Ito, Takurou Mizuno, Keiichirou Ishigami, Kengo Kuroki, Naoto Maekawa, Daisuke Usuda, Takuro Morita, Kazu Hamada, Susumu Takagi, Kento Takeshima, Shinya Yamada, Ryusho Sangen, Toshihide Izumida, Hideyuki Mori, Jun Kiyosawa, Atsushi Saito, Masaharu Iguchi, Takeshi Nakahashi, Yuji Kasamaki, Akihiro Fukuda, Tsugiyasu Kanda, Masashi OkuroMedicine100:e276382021年11月
  • The 12-Month Administration of Tofogliflozin for Glycemic Control with Monitoring Electrolytes, Renal and Cardiac Function in Japanese Elderly Patients with Type 2 Diabetes MellitusToshihiro Higashikawa, Tomohiko Ito, Takurou Mizuno, Keiichiro Ishigami, Masaru Kohori, Kunihiro Mae, Daisuke Usuda, Kazu Hamada, Takuro Morita, Kento Takeshima, Susumu Takagi, Toshihide Izumida, Kengo Kuroki, Ryusho Sangen, Atsushi Saito, Masaharu Iguchi, Yuji Kasamaki, Takeshi Nakahashi, Akihiro Fukuda, Tsugiyasu Kanda, Masashi OkuroInternational Journal of Geriatrics and Gerontology5:1-82021年02月
  • Effects of a Lower Lipid Diet and Exercise on Cognitive Disturbances with the Induction of Calcineurin 1 and Brain-derived Neurotrophic Factor Expressions in the Hippocampi of Obese Apolipoprotein E Knockout MiceShuo Wang, Haicong Li, Mineko Nishijo, Yoshikazu Nishino, Nobuo Kato, Yuji Kasamaki, Tadashi Ueda, Tsugiyasu KandaJMA Journal4:409-4142021年
  • Perioperative Complications,Urinary Retention and Aspiration Pneumonia in Patients with Femoral Neck and Trochanter Fractures Under the Multidisciplinary Program:A Study at Bone Femoral Neck and Trochanter Fracture Center,Toyama Municipal HospitalToshihiro Higashikawa, Kenji Shigemoto, Daisuke Usuda, Hiromi Inushima, Kazu Hamada, Kenichi Goshima, Takuro Morita, Kimiko Usuda, Miyako Yamaguchi, Manabu Moriyama, Masahiro Hangyou, Shigeki Takashima, Tadami Matsumoto, Takeshi Horii, Tugiyasu Kanda, Masashi Okuro, Takeshi SawaguchiInternational Journal of Geriatrics and Gerontology4:1-52020年12月
  • Combination effects of a fatty diet and exercise on the depressive state and cardioprotection in apolipoprotein E knockout mice with a change in RCAN1 expressionWang Shuo, Haicong Li, Nishijo Muneko, Nishino Yoshikazu, Nobuo Kato, Yuji Kasamaki, Tadashi Ueda, Tsugiyasu KandaJournal of International Medical Research48:3000605209640162020年11月
  • Functional Decline Status for the Development of Aspiration Pneumonia in Elderly Patients with Femoral Neck and Trochanteric FracturesToshihiro Higashikawa, Takuro Morita, Manabu Moriyama, Hiromi Inujima, Masahiro Hangyou, Kimiko Usuda, Shigeto Morimoto, Masashi Okuro, Tadami Matsumoto, Kenji Shigemoto, Kenichi Goshima, Takeshi Sawaguchi, Daisuke Usuda, Shigeki Takashima, Tsugiyasu KandaOpen Access Journal of Biomedical Science3:679-6822020年10月
  • Mortality and the Risk Factors in Elderly Female Patients With Femoral Neck and Trochanteric FracturesToshihiro Higashikawa, Kenji Shigemoto, Kenichi Goshima, Takeshi Horii, Daisuke Usuda, Takuro Morita, Manabu Moriyama, Hiromi Inujima, Masahiro Hangyou, Kimiko Usuda, Shigeto Morimoto, Tadami Matsumoto, Shigeki Takashima, Tsugiyasu Kanda, Masashi Okuro, Takashi SawaguchiJournal of Clinical Medicine Research12:668-6732020年09月
  • Gender Differences in Cardiac Function Following Three-Month Administration of Tofogliflozin in Patients With Diabetes MellitusToshihiro Higashikawa, Tomohiko Ito, Takurou Mizuno, Keiichiro Ishigami, Masaru Kohori, Kunihiro Mae, Daisuke Usuda, Kento Takeshima, Susumu Takagi, Toshihide Izumida, Shinya Yamada, Kengo Kuroki, Ryusho Sangen, Atsushi Saito, Masaharu Iguchi, Yuji Kasamaki, Takeshi Nakahashi, Akihiro Fukuda, Tsugiyasu Kanda, Masashi OkuroJournal of Clinical Medicine Research12:530-5382020年08月
  • New score including daily life independence levels with dementia is associated with the onset of deep vein thrombosis in frail older adultsKeisuke Nakanishi, Tsugiyasu Kanda, Takashi Kobata, Masayuki Mori, Shinya Yamada, Yuji KasamakiGeriatrics & Gerontology International20:414-4212020年05月
  • Effects of Tofogliflozin on Cardiac Function in Elderly Patients With Diabetes MellitusToshihiro Higashikawa, Tomohiko Ito, Takurou Mizuno, Keiichirou Ishigami, Masaru Kohori, Kunihiro Mae, Daisuke Usuda, Susumu Takagi, Ryusho Sangen, Atsushi Saito, Masaharu Iguchi, Yuji Kasamaki, Akihiro Fukuda, Tsugiyasu Kanda, Masashi OkuroJournal of Clinical Medicine Research12:165-1712020年03月
  • Urinary retention as a postoperative complication associated with functional decline in elderly female patients with femoral neck and trochanteric fractures A retrospective study of a patient cohortHigashikawa Toshihiro, Shigemoto Kenji, Goshima Kenichi, Usuda Daisuke, Okuro Masashi, Moriyama Manabu, Inujima Hiromi, Hangyou Masahiro, Usuda Kimiko, Morimoto Shigeto, Matsumoto Tadami, Takashima Shigeki, Kanda Tsugiyasu, Sawaguchi TakeshiMEDICINE98:e160232019年06月
  • The effects of 12-month administration of tofogliflozin on electrolytes and dehydration in mainly elderly Japanese patients with type 2 diabetes mellitus.Higashikawa Toshihiro;Ito Tomohiko;Mizuno Takurou;Ishigami Keiichirou;Kohori Masaru;Mae Kunihiro;Sangen Ryusho;Usuda Daisuke;Saito Atsushi;Iguchi Masaharu;Kasamaki Yuji;Fukuda Akihiro;Saito Hitoshi;Kanda Tsugiyasu;Okuro MasashiJOURNAL OF INTERNATIONAL MEDICAL RESEARCH46:5117-51262018年12月
  • Atypical lipomatous tumor in the ligamentum teres of liver: A case report and review of the literatureUsuda Daisuke, Takeshima Kento, Sangen Ryusho, Nakamura Kisuke, Hayashi Kei, Okamura Hideyuki, Kawai Yasuhiro, Kasamaki Yuji, Iinuma Yoshitsugu, Saito Htoshi, Kanda Tsugiyasu, Urashima SachioWorld Journal of Clinical Cases6:548-5532018年10月
  • Procalcitonin and albumin as prognostic biomarkers in elderly patients with a risk of bacterial infection.Higashikawa Toshihiro;Okuro Masashi;Ishigami Keiichirou;Mae Kunihiro;Sangen Ryusho;Mizuno Takurou;Usuda Daisuke;Saito Atushi;Kasamaki Yuji;Fukuda Akihiro;Saito Hitoshi;Morimoto Shigeto;Kanda TsugiyasuJOURNAL OF INTERNATIONAL MEDICAL RESEARCH46:2606-26142018年07月
  • Interleukin-18 as a diagnostic marker of adult-onset Still's disease in older patients: a case report and review of the literature.Usuda Daisuke, Furumura Yoshiki, Takeshima Kento, Sangen Ryusho, Kawai Yasuhiro, Kasamaki Yuji, Iinuma Yoshitugu, Kanda Tsugiyasu.Journal of medical case reports12:10.1186/s13256-018-1735-7.2018年07月
  • Evaluation of B-type natriuretic peptide as prognostic marker in patients with pneumonia: An observational studyDaisuke Usuda , Yoshiki Furumura, Ryusho Sangen, Yu Hashimoto, Jun Kawamukai, Emiri Muranaka, Yasuhiro Kawai, Yuji Kasamaki, Yoshitsugu Iinuma, Tsugiyasu KandaInternal Medicine Review4:1-282018年03月
  • Diagnosis of myxedema coma complicated by renal failure: a case reportAkiteru.Takamura, R.Sangen, Y.Furumura, D.Usuda, Y.Kasamaki, T.KandaClinical Case Reports5:399-4022017年02月
  • Gastroenteritis in Japanese Females Caused by Shigella flexneri without Definite. Infection Route: A Case Report and Mini-Review of LiteratureDaisuke Usuda, Shinya Yamada, Kento Takeshima, Ryusho Sangen, Masaharu Iguchi, Yasuhiro Kawai, Yuji Kasamaki, Yoshitsugu Iinuma and Tsugiyasu KandaJournal Clinical Case Reports7:10001021 2017年
  • Infective endocarditis following tumor necrosis factor-α antagonist therapy for management of psoriatic erythroderma: a case report.Mizuno Takuro;Kiyosawa Jun;Fukuda Akihiro;Watanabe Seiji;Kurose Nozomu;Nojima Takayuki;Kanda TsugiyasuJournal of medical case reports11:352017年
  • Autopsy-proven intravascular lymphoma presenting as rapidly recurrent strokesD.Usuda, M.Arahata, R.Temaru, Y.Iinuma, T.Kanda, S.HayashiCase reports in oncology9:148-1532016年03月
  • Validation of a B-type natriuretic peptide as a prognostic marker in pneumonia patients: a prospective cohort study.D.Usuda, R.Sangen, Y.Hashimoto, E.Muranaka, Y.Iinuma, T.KandaBMJ open6:e010440-e0104402016年02月
  • Interstitial Pneumonia in a 94-Year-Old Woman with MPO-ANCA Positive VasculitisD.Usuda, R.Sangen, Y.Iwata, T.KandaCase Reports in Clinical Medicine5:61-652016年02月
  • Blood pressure and disability-free survival among community-dwelling diabetic and non-diabetic elderly patients receiving antihypertensive treatmentT.Higashikawa, Y.Hamazaki, O.Iritani, T.Morita, T.Himeno, T.Okuno, H.Yano, K.Watanabe, M.Okuro, T.Kanda, S.MorimotoGeriatrics Gerontology International16:365-3732015年02月
  • 富山県氷見市のへき地居住者に対する認知症スクリーニング調査松田幸久, 竹本早知子, 橋本玲子, 玉井 顕, 神田享勉, 石﨑昌夫, 三輪高喜, 森本茂人, 北村 修, 川﨑康弘金沢医科大学雑誌39:67-742014年12月
  • Endocardial invasion of lung cancer undiagnosable before autopsyT.Mizuno, K.Ishigami, S.Yamada, H.Tsuchiya, C.Nakajima, R.Sangen, M.Fukushima, H.Minato, T.Nojima, A.Saito, N.Hayashi, H.Atsumi, T.Ito, M.Iguchi, D.Usuda, H.Okamura, S.Urashima, M.Asano, J.Kiyosawa, A.Fukuda, N.Takekoshi, T.KandaCase reports in oncology [electronic resource]7:144-1482014年03月
  • Cardiac BDNF/TrkB signaling can be induced by calorie restriction with improved physical activity in obese miceR Chen, T. Mizuno, T.KandaInternet J of Cardiovasc Res18;1617-16202013年08月
  • Spontaneous remission of epstein-barr virus-positive diffuse large b-cell lymphoma of the elderly.T.Kanda, T.Mizuno, M.Ishigaki, K.Nakajima, T.Matsue, M.Fukushima, H.Minato, N.Nojima, S.Atsushi, K.Ishigami, H.Atsumi, T.Ito, M.Iguchi, D.Usuda, H.Okamura, S.Urashima, M.Asano, A.Fukuda, Y.Izumi, N.TakekoshiCase reports in oncology [electronic resource]6:269-2742013年06月
  • Cardiac BDNF/TrkB signaling can be induced by calorie restriction with improved physical activity in obese mice.T.Kanda, R.Chen, T.Mizuno, D.Sakamoto, D.Usuda, M.Mori, M.Takahashi, N.Kato, H.SuminoThe Internet Journal of Cardiovascular Research82013年
  • 在宅患者が導尿を行うに当たり抱いた不安や経験したトラブルの有無とその内容久司一葉, 前田修子, 森山 学, 島崎猛夫, 神田享勉, 河野由美子癌と化学療法38(supplⅠ): 103-1052011年12月
  • 在宅導尿患者への医療機関からの物品供給状況に関する研究前田修子, 森山 学, 島崎猛夫, 神田享勉, 河野由美子, 久司一葉癌と化学療法38(supplⅠ):109-1112011年12月
  • 在宅導尿患者における使用物品の自己購入状況とその負担感に関する実態河野由美子, 前田修子, 森山 学, 島崎猛夫, 神田享勉, 久司一葉癌と化学療法38(supplⅠ):106-1082011年12月
  • Two types of Brugada-like ST-elevation in patients with febrile infectionT.Mizuno, K.Ishigami, D. Sakamoto, R.Isahii, T.Kanda金沢医科大学雑誌36:124-1262011年
  • Interleukin-6 expressing colon cancer with multiple hepatic metastasesA.Tempaku, T.Mizuno, M.Hasegawa, A.Saito, N.Yamashita, H.Atsumi, T.Ito, K.Ishigami, M.Miura, Y.Izumi, N.Kurose, H.Minato, T.Nojima, T.Kanda, N.Takekoshi金沢医科大学雑誌36:106-1102011年
  • Hypernatremia, rhabdomyolysis and acute renal failureK.Ishigami, N.Yamashita, K.Konishi, A.Saito, M.Fukura, M.Hasegawa, T.Kanda, T.Ito, T.Kigoshi, Y.Izumi, N.Takekoshi金沢医科大学雑誌35:68-692010年08月
  • Clinical risk factors in regional brain ischemia using single photon emission computed tomographyR.Chen, F.Liang, K.Ishigami, T.Kanda, L.Zeng, A.Saito, M.Hasegawa, N.Yamashita, T.Itoh, T.Kigoshi, Y.Izumi, N.Takekoshi, S.MorimotoJournal of the American Geriatrics Society.58:1411-14122010年07月
  • Hypoglycemia in elderly diabetes mellitus-free patients :Case reports and a review of literatureK.Konishi, A.Saito, K.Ishigami, M.Fukura, M.Hasegawa, N.Yamashita, T.Kanda, T.Ito, T.Kigoshi, Y.Izumi, N.Takekoshi金沢医科大学雑誌35:13-152010年06月
  • The effects of a PPARα agonist on myocardial damage in obese diabetic mice with heart failureR.Chen, F.Liang, S.Morimoto, Q.Li, J.Moriya, J.Yamakawa, T.Takahashi, K.Iwai, T.KandaInternational Heart Journal51:199-2062010年05月
  • Traditional chinese medicine for chronic fatigue syndromeR.Chen, J.Moriya, J.Yamakawa, T.Takahashi, T.KandaEvidence-based complementary and alternative medicine : eCAM.7:3-102010年03月
  • A Kampo medicine, boiogito, inhibits obesity in ovariectomized ratsJ.Yamakawa, J.Moriya, T.Takahashi, A.Ishige, Y.Motoo, F.Yoshizaki, T.KandaEvidence-based complementary and alternative medicine : eCAM.7:87-952010年01月
  • Mao-to prolongs the survival of and reduces TNF-α expression in mice with viral myocarditisZ.Shijie, J.Moriya, J.Yamakawa, R.Chen, T.Takahashi, H.Sumino, T.Nakahashi, K.Iwai, S.Morimoto, N.Yamaguchi, T.KandaEvidence-based complementary and alternative medicine : eCAM.7:341-3492010年
  • Suicides in aged patients; Case reports and review of the literatureM.Fukura, A.Saito, K.Ishigami, K.Konishi, M.Hasegawa, JL.Wu, H.Kawahara, T.Kanda, T.Kigoshi, N.Takekoshi金沢医科大学雑誌34:14-162009年06月
  • Silent information regulator, sirtuin 1, and age-related diseasesL.Zeng, R.Chen, F.Liang, H.Tsuchiya, H.Murai, T.Nakahashi, K.Iwai, T.Takahashi, T.Kanda, S.MorimotoNature clinical practice. Rheumatology.9:7-152009年
  • Candesartan improves myocardial damage in obese mice with viral myocarditis and induces cardiac adiponectinF.Yu, R.Chen, T.Takahashi, H.Sumino, S.Morimoto, T.Nakahashi, K.Iwai, M.Matsumoto, T.KandaInternational journal of cardiology129:414-4212008年11月
  • Chronic fatigue syndrome and the central nervous systemR.Chen, FX.Liang, J.Moriya, J.Yamakawa, H.Sumino, T.Kanda, T.TakahashiThe Journal of international medical research.36:867-8742008年09月
  • A novel adipocytokine, visceral adipose tissue-derived serine protease inhibitor(vaspin),and obesityQ.Li, R.Chen, J.Moriya, J.Yamakawa, H.Sumino, T.Kanda, T.TakahashiThe Journal of international medical research.36:625-6292008年07月
  • A large ovarian tumor mimicking the accumulation of ascitesJ.Moriya, J.Yamakawa, R.Chen, H.Takagi, S.Makinoda, T.Takahashi, T.Kanda金沢医科大学雑誌33:31-322008年06月
  • 慢性疲労症候群に対する診療神田享勉Modern Physician28:4132008年03月
  • Peroxisome proliferator-activated receptors(ppars) and their agonists for hypertension and heart failure: are the reagents beneficial or harmful?R.Chen, F.Liang, J.Moriya, J.Yamakawa, T.Takahashi, L.Shen, T.KandaInternational journal of cardiology130:131-1392008年03月
  • Brain atrophy in a murine model of chronic fatigue syndrome and beneficial effect of hochu-ekki-to(TJ-41)R.Chen, J.Moriya, J.Yamakawa, T.Takahashi, Q.Li, S.Morimoto, K.Iwai, H.Sumino, N.Yamaguchi, T.KandaNeurochemical research33:1759-17672008年03月
  • 慢性疲労症侯群神田享勉Modern Physician28:260-2612008年02月
  • Immobilization stress inhibits intimal fibromuscular proliferation in the process of arterial remodeling in ratsK.Iwai, T.Takahashi, T.Nakahashi, K.Nomura, M.Atsumi, L.Zeng, K.Ishigami, T.Kanda, N.Yamaguchi, S.MorimotoHypertension research : official journal of the Japanese Society of Hypertension.31:977-9862008年
  • A kampo medicine, boi-ogi-to, inhibits obesity in ovariectomized ratsJ.Yamakawa, J.Moriya, T.Takahashi, A.Ishige, Y.Motoo, F.Yoshizaki, T.KandaeCAM420132007年11月
  • Relationship between brachial arterial endothelial function and lumber spine bone mineral density in postmenopausal women(H.Sumino), S.Ichikawa, S.Kusama, T.Takahashi, H.Sakamoto, H.Kumakura, Y.Takayama, T.Kanda, M.Murakami, M.KurabayashiCirculation journal : official journal of the Japanese Circulation Society71:1555-15592007年10月
  • 疲労を回復する外来神田享勉, 髙橋 孝Medical Practice24(9):16432007年09月
  • Bariatric surgery for morbid obesityR.Chen, T.Takahashi, T.KandaThe New England journal of medicine357:1158-11602007年09月
  • 半健康人を救え神田享勉, 髙橋 孝Medical Practice24(8)14532007年08月
  • Reduced-energy diet improves survival of obses KKAy mice with viral myocarditis:induction of cardiac adiponectin expressionT.Kanda, S.Saegusa, T.Takahashi, H.Sumino, S.Morimoto, T.Nakahashi, K.Iwai, M.MatsumotoInternational journal of cardiology119:310-3182007年07月
  • Prostate cancer producing carcinoembryonic antigen and carbohydrate antigen 19-9 without expression of prostate-specific antigenK.Miyazawa, T.Itoh, E.Kinoshita, T.Nojima, T.Takahashi, T.Kanda, K.Suzuki金沢医科大学雑誌32:29-312007年06月
  • Oral administration of candesartan improves the survival of mice with viral myocarditis through modification of cardiac adiponectin expressionS.Saegusa, Y.Fei, T.Takahashi, H.Sumino, J.Moriya, K.Kawaura, J.Yamakawa, T.Itou, S.Morimoto, T.Nakahashi, K.Iwai, M.Matsumoto, T.KandaCardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy.21:155-1602007年06月
  • Hepatocyte growth factor and visfatin in elderly bedridden patientsT.Kanda, T.Takahashi, H.Sumino, T.Nakahashi, K.Iwai, S.Morimoto, M.MatsumotoJournal of the American Geriatrics Society.55:963-9652007年06月
  • Influenza VaccinesT.Takahashi, T.Kanda, N.YamaguchiThe New England journal of medicine356:1172-11732007年03月
  • Acupuncture regulates leukocyte subpopulations in human peripheral bloodN.Yamaguchi, T.Takahashi, M.Sakuma, T.Sugita, K.Uchikawa, S.Sakaihara, T.Kanda, M.Arai, K.KawakitaEvidence-based complementary and alternative medicine : eCAM.4:447-4532007年02月
  • Acupuncture regulates leukocyte subpopulations in human peripheral bloodNobuo Yamaguchi, Takashi Takahashi, Masahiro Sakuma, Toshiroh Sugita, Kumiko Uchikawa, Satoshi Sakaihara, Tsugiyasu Kanda, Matsuo Arai, Kenji KawakitaEvidence-based complementary and alternative medicine : eCAM.4:447-4532007年02月
  • Tilting-induced decrease in systolic blood pressure in bedridden hypertensive elderly inpatients:effects of azelnidipineS.Morimoto, T.Takahashi, K.Okaishi, T.Nakahashi, K.Nomura, T.Kanda, M.Okuro, H.Murai, T.Nishino, M.MatsumotoHypertension research : official journal of the Japanese Society of Hypertension.29:943-9492006年12月
  • 冷感、異常知覚に牛車腎気丸が有効であった結節性多発性血管炎の1例山川淳一, 守屋純二, 日下一也, 伊藤 透, 元雄良治, 神田享勉日本東洋医学雑誌57:651-6542006年09月
  • Angiotensin Ⅰ-converting enzyme inhibitor improves reactive hyperemia in elderly hypertensives with arteriosclerosis obliteransM.Okuro, S.Morimoto, T.Takahashi, K.Okaishi, T.Nakahashi, H.Murai, K.Iwai, T.KandaHypertension research : official journal of the Japanese Society of Hypertension.29:655-6632006年09月
  • Advanced oesophageal carcinoma in an 84- year-old treated with chemoradiotherapyK.Kusaka, T.Itoh, K.Kawaura, J.Moriya, J.Yamakawa, T.Takahashi, M.Oguchi, H.Tonami, I.Yamamoto, T.KandaThe Journal of international medical research.34:437-4402006年07月
  • Expression of ephrin in retinal neovascularization and iris rubeosis(T.Yuuki), T.Kanda, S.KishiThe Journal of international medical research.34:485-4942006年06月
  • となりの総合診療部第17回 金沢医科大学病院総合診療科高橋 孝, 神田享勉JIM16:430-4312006年05月
  • Traditional chinese medicine and kampo: a review from the distant past for the futureF Yu, T.Takahashi, J.Moriya, K.Kawaura, J.Yamakawa, K.Kusaka, T.Itoh, S.Morimoto, N.Yamaguchi, T.KandaThe Journal of international medical research.34:231-2392006年05月
  • Angiotensin-Ⅱ receptor antagonist alleviates non-alcoholic fatty liver in kkay obese mice with type2 diabetesF.Yu, T.Takahashi, J.Moriya, K.Kawaura, J.Yamakawa, K.Kusaka, T.Itoh, H.Sumino, S.Morimoto, T.KandaThe Journal of international medical research.34:297-3022006年05月
  • Elevated arterial stiffness in postmenopausal women with osteoporosis(H.Sumino), S.Ichikawa, S.Kasama, T.Takahashi, H.Kumakura, Y.Takayama, T.Kanda, T.Sakamaki, M.KurabayashiMaturitas55:212-2182006年02月
  • Different effects of oral conjugated estrogen and transdermal estradiol on arterial stiffness and vascular inflammatory markers in postmenopausal women(H.Sumino), S.Ichikawa, S.Kasama, T.Takahashi, H.Kumakura, Y.Takayama, T.Kanda, M.KurabayashiAtherosclerosis.189:436-4422006年02月
  • Conjugated estrogen plus medroxyprogesterone does not impair blood rheological properties in hypertensive postmenopausal women(H.Sumino), S.Ichikawa, T.Takahashi, H.Sakamoto, K.Goto-Onozato, S.Koya, T.Kanda, M.Nara, K.Seki, M.Murakami, M.KurabayashiMaturitas53:306-3142006年02月
  • Outbreak of human metapneumovirus infection in elderly inpatients in japan(H.Honda), J.Iwahashi, T.Kashiwagi, Y.Imamura, N.Hamada, T.Anraku, S.Ueda, T.Kanda, T.Takahashi, S.MorimotoJournal of the American Geriatrics Society.54:177-1802006年01月
  • Impaired expression of cardiac adiponectin in leptin-deficient mice with viral myocarditisT.Takahashi, F.Yu, S.Saegusa, H.Sumino, T.Nakahashi, K.Iwai, S.Morimoto, M.Kurabayashi, T.KandaInternational Heart Journal47:107-1232006年01月
  • Beneficial effect of brewers' yeast extract on daily activity in a murine model o f chronic fatigue syndromeT.Takahashi, Y.Fei, Z.Shi-jie, J.Moriya, H.Sumino, S.Morimoto, N.Yamaguchi, T.KandaeCAM3:109-1152006年01月
  • Globalization of kampo medicineT.Kanda, J.Yamakawa, J.Moriya, S.Saegusa, K.Kawaura, F.Yu, K.Kusaka, T.Takahashi, T.Itoh金沢医科大学雑誌30:297-3012005年12月
  • Hypoadiponectinemia in bedridden female patients younger than 75T.Kanda, T.Takahashi, H.Sumino, T.Nakahashi, K.Iwai, S.Morimoto, M.MatsumotoJournal of the American Geriatrics Society.53:2039-20412005年11月
  • Reduction of pneumonia risk by an angiotensin Ⅰ-converting enzyme inhibitor in elderly japanese inpatients according to insertion/deletion polymorphism of the angiotensin Ⅰ-converting enzyme geneT.Takahashi, S.Morimoto, K.Okaishi, T.Kanda, T.Nakahashi, M.Okuro, H.Murai, Y.Nishimura, K.Iwai, M.MatsumotoAmerican journal of hypertension : journal of the American Society of Hypertension.18:1353-13592005年10月
  • Extract from inflamed skin of rabbits increases enkephalin concentrations in cerebrospinal fluid in ratsS.Morimoto, T.Takahashi, HL.Jackman, EG.Erdos, T.Kanda, H.Ohde, W-M. Liu, M.Okuro, K.Nomura, M.Matsumoto金沢医科大学雑誌30:141-1462005年10月
  • Spontaneous fractures of long bones associated with joint contractures in bedridden elderly inpatients:clinical features and outcome(S.Takamoto), S.Saeki, Y.Yabumoto, H.Masaki, T.Onishi, S.Morimoto, M.Matsumoto, T.Takahashi, T.KandaJournal of the American Geriatrics Society.53:1439-14412005年08月
  • Inhibitin of cyclooxygenase-2 enhances myocardial damage in a mouse model of viral myocarditisT.Takahashi, S.Zhu, H.Sumino, S.Saegusa, T.Nakahashi, K.Iwai, S.Morimoto, T.KandaLife sciences.78:195-2042005年08月
  • Effect of transdermal hormone replacement therapy on the monocyte chemoattractant protein-1 concentrations and other vascular inflammatory markers and on endothelial function in postmenopausal women(H.Sumino), S.Ichikawa, Y.Ohyama, T.Takahashi, Y.Saito, T.Nakamura, T.Kanda, M.KurabayashiThe American journal of cardiology.96:148-1532005年07月
  • Kampo medicines minimized a variety of complaints treated with twenty-eight western medicines: a case of 81-year-old womanJ.Moriya, T.Takahashi, J.Yamakawa, S.Saegusa, T.Itoh, K.Kusaka, K.Kawaura, F.Yu, T.Kanda金沢医科大学雑誌30:12-152005年06月
  • Three-point fixation of stomach to abdominal wall in the percutaneous endoscopic gastrostomy procedureK.Kusaka, T.Itoh, K.Kawaura, J.Yamakawa, T.Takahashi, T.KandaEndoscopy.37:4942005年03月
  • Effect of antihypertensive therapy on blood rheology in patients with essential hypertension(H.Sumino), M.Nara, K.Seki, T.Takahashi, T.Kanda, S.Ichikawa, K.Goto-Onozato, S.Koya, M.Murakami, M.KurabayashiThe Journal of international medical research.33:170-1772005年03月
  • Adiponectin replacement therapy attenuates myocardial damage in leptin-deficient mice with viral myocarditisT.Takahashi, S.Saegusa, H.Sumino, T.Nakahashi, K.Iwai, S.Morimoto, T,KandaThe Journal of international medical research.33:207-2142005年03月
  • Clinical features associated with circulating concentration of soluble leptin receptor in patients with diabetes(N.Kotajima), T.Takahashi, H.Ito, H.Sumino, Y.Fukumura, M.Kurabayashi, M.Murakami, T.KandaThe Journal of international medical research.33:61-672005年01月
  • Electromagnetic fields inhibit endothelin-1 production stimulated by thrombin in endothelial cellsS.Morimoto, T.Takahashi, K.Shimizu, T.Kanda, K.Okaishi, M.Okuro, H.Murai, Y.Nishimura, K.Nomura, H.Tsuchiya, I.Ohashi, M.MatsumotoThe Journal of international medical research.33:545-5542005年
  • Adiponectin, t-cadherin and tumour necrosis factor-α in damaged cardiomyocytes from autopsy specimensT.Takahashi, S.Saegusa, H.Sumino, T.Nakahashi, K.Iwai, S.Morimoto, T.Nojima, T.KandaThe Journal of international medical research.33:236-2442005年
  • Vascular endothelial growth factor is an autocrine growth factor for cardiac myxoma cells(H.Sakamoto), T.Kanda, et al.Circulation journal : official journal of the Japanese Circulation Society68:488-4932004年
  • Transient glucose deprivation causes upregulation of heme oxygenase-1 and cyclooxygenase-2 expression in cardiac fibroblasts.*K.Takaeda, *J.Lin, *S.Okubo, *S.Akazawa-Kudoh, *K.Kajinami, *S.Kanemitsu, *H.Tsugawa, T.Kanda, *S.Matsui, *N.TakekoshiJournal of molecular and cellular cardiology.36:821-8302004年
  • Selective binding of sucralfate to endoscopic mucosal resection-induced gastric ulcer: evaluation of aluminum adherence.T.Itoh, K.Kusaka, K.Kawaura, J.Yamakawa, T.Takahashi, T.Kanda, et al.The Journal of international medical research.32:520-5292004年
  • Production of endothelin-1 and big endothelin-1 by human cardiac myxoma cells - implications for the origin of myxomas-(H.Sakamoto), T.Kanda, et al.Circulation journal : official journal of the Japanese Circulation Society68:1230-12322004年
  • Plasma adiponectin levels in post-menopausal women receiving hormone replacement therapy.(H.Sumino), T.Takahashi, T.Itoh, K.Kusaka, J.Yamakawa, T.Kanda, et al.The Journal of international medical research.32:639-6452004年
  • Panic attack symptoms in a patient with left temporal lobe epilepsy.S.Saegusa, T.Takahashi, J.Moriya, J.Yamakawa, T.Itoh, K.Kusaka, K.Kawaura, T.KandaThe Journal of international medical research.32:94-962004年
  • Leptin deficiency enhances myocardial necrosis and lethality in a murine model of viral myocarditis.T.Kanda, T.Takahashi, *S.Kudo, *T.Takeda, *H.Tsugawa, *N.TakekoshiLife sciences.75:1435-14472004年
  • Interleukin-6-induced reciprocal expression of SERCA and natriuretic peptides mRNA in cultured rat ventricular myocytesT.Tahaka, T.Kanda, T.Takahashi, S.Saegusa, J.Moriya, et al.The Journal of international medical research.32:57-612004年
  • Interleukin-6 and cardiovascular diseases.T.Takahashi, T.KandaJapanese Heart Journal45:183-1932004年
  • Features of patients with influenza virus infection examined in the emergency department of a university hospital in north-western Japan*S.Mashiba, T.Takahashi, *N.Hayashi, *H.Morita, *T.Gotoh, *M.Nakata, *Y.Watoh, T.Kanda, *M.TakinoThe Journal of international medical research.32:331-3362004年
  • Effect of the serotonin blocker sarpogrelate on circulating interleukin-18 levels in patients with diabetes and arteriosclerosis obliteransJ.Yamakawa, T.Takahashi, S.Saegusa, J.Moriya, T.Itoh, K.Kusaka, K.Kawaura, XQ.Wang, T.KandaThe Journal of international medical research.32:166-1692004年
  • Effect of hochu-ekki-to(TJ-41),a Japanese herbal medicine,on daily activity in a murine model of chronic fatigue syndrome.XQ.Wang, T.Takahashi, S.Zhu, J.Moriya, S.Saegusa, J.Yamakawa, K.Kusaka, T.Itoh, T.KandaeCAM1:203-2062004年
  • Detection of toxoplasma gondii by polymerase chain reaction in cerebrospinal fluid from human immunodeficiency virus-1-infected japanese patients with focal neurological signs.M.Goto, T.Takahashi, T.Kanda, et al.The Journal of international medical research.32:665-6702004年
  • Chronotropic effect of the anti-thrombotic agent cilostazol in a patient with sick sinus syndrome and syncope.J.Moriya, T.Takahashi, *Y.Nomura, K.Kawaura, K.Kusaka, J.Yamakawa, *N.Fujioka, *S.Okubo, T.Itoh, T.KandaThe Journal of international medical research.32:549-5512004年
  • 肥満と感染-レプチンを軸として-日下一也, 神田享勉Infection Inflammation Immunity33: 55-572003年
  • 炎症性サイトカインと発熱「発熱-全身的な基礎疾患の理解とその対策について-」高橋 孝, 神田享勉カレントテラピー21: 1083-10862003年
  • アミロイドーシス,サルコイドーシスとの心障害神田享勉今月の治療11 (臨増): S344-3462003年
  • Utility of testing bronchoalveolar lavage fluid for cryptococcal ribosomal DNAT. Takahashi, T. Kanda, et al.The Journal of international medical research.31: 324-3292003年
  • Upregulation of cardiac ghrelin mRNA in leptin-deficient and leptin receptor-deficient mice with viral myocarditisT. Kanda, T. Takahashi, T. Itoh, K. Kusaka, J. Yamakawa, *S. Kudo, *T. Takeda, *H. Tsugawa, *N. TakekosiThe Journal of international medical research.31: 503-5082003年
  • Spontaneously identified gastric sarcoidosis: a report of three casesK. Kawaura, T. Takahashi, K. Kusaka, J. Yamakawa, T. Itoh, T. KandaThe Journal of international medical research.31: 239-2432003年
  • Plasma interleukin-6 is associated with coagulation in poorly controlled patients with type 2 diabetes(Y. Aso), T. Kanda, et al.Diabetic medicine : a journal of the British Diabetic Association.20: 930-9342003年
  • Immunohistochemical study of surgically excised choroidal neovascular membranes(T. Sato), T. Kanda, et al.The Journal of international medical research.31: 402-4062003年
  • Hormone replacement therapy decreases insulin resistance and lipid metabolism in Japanese postmenopausal women with impaired and normal glucose tolerance(H. Sumino), T. Kanda, et al.Hormone research.60: 134-1422003年
  • Hormone replacement therapy causes a decrease in hepatocyte growth factor in hypertensive women(K. Tamama), T. Kanda, et al.Journal of human hypertension.21: 1151-11562003年
  • Herpes simplex esophagitis from 1307 autopsy casesT. Itoh, T. Takahashi, K. Kusaka, K. Kawaura, J. Yamakawa, T. KandaJournal of gastroenterology and hepatology.18: 1407-14112003年
  • Effects of hormone replacement therapy on weight, abdominal fat distribution, and lipid levels in Japanese postmenopausal women(H. Sumino), T. Kanda, et al.International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.27: 1044-10512003年
  • Effects of hormone replacement therapy on serum angiotensin-converting enzyme activity and plasma bradykinin in postmenopausal women according to angiotensin-converting enzyme-genotype(H. Sumino), T. Kanda, et al.Hypertension research : official journal of the Japanese Society of Hypertension.26: 53-582003年
  • Effects of hormone replacement therapy on office and ambulatory blood pressure in Japanese hypertensive postmenopausal women(H. Sumino), T. Kanda, et al.Hypertension research : official journal of the Japanese Society of Hypertension.26: 369-3762003年
  • Effects of hormone replacement therapy on circulating docosahexaenoic acid and eicosapentaenoic acid levels in postmenopausal women(H. Sumino), T. Kanda, et al.Endocrine journal.50: 51-592003年
  • Effects of angiotensin II receptor antagonists on insulin resistance syndrome and leptin in sucrose-fed spontaneously hypertensive rats(M. Umeda), T. Kanda, et al.Hypertension research : official journal of the Japanese Society of Hypertension.26: 485-4922003年
  • Congestive heart failure induced by the combination of atrial fibrillation and tricuspid regurgitationK. Kusaka, T. Takahashi, T. Kanda, et al.The Journal of international medical research.31: 475-4802003年
  • Brugada-like electrocardiographic changes during influenza infectionK. Kusaka, J. Yamakawa, K. Kawaura, T. Itoh, T. Takahashi, T. KandaThe Journal of international medical research.31: 244-2462003年
  • A novel serotonin blocker, sarpogrelate, increases circulating adiponectin levels in diabetic patients with arteriosclerosis obliteransJ. Yamakawa, T. Takahashi, T. Itoh, K. Kusaka, K. Kawaura, X-Q. Wang, T. KandaDiabetes Care.26: 2477-24782003年
  • 肥満と健康神田享勉石川 自治と教育564: 42-532002年
  • 総合診療部実習で保健学科検査技術科専攻の学生は何を感じ取ったか?(坂本浩之助), 神田享勉, 他The Kitakanto Medical Journal52: 369-3752002年
  • 炎症性サイトカインの測定意義について教えてください神田享勉モダンメデイア48: 190-1922002年
  • The effect of the herbal medicine dai-kenchu-to on post-operative ileusT. Itoh, J. Yamakawa, T. Kanda, et al.The Journal of international medical research.30: 428-4322002年
  • Interleukin-18 reduces expression of cardiac tumor necrosis factor-alpha and atrial natriuretic peptide ina murine model of viral myocarditis(A. Yoshida), T. Kanda, et al.Life Sci 200270: 1225-12342002年
  • Improved myocardial ischemia/reperfusion injury in mice lacking tumor necrosis factor-alpha(N. Maekawa), T. Kanda, et al.Journal of the American College of Cardiology.39: 1229-12352002年
  • Genetic diversity of drug targets including dihydropteroate syuthase, dihydrofolate reductase and cytochrome B in pneumocysitis carinii F.SP.hominis isolates in Japan(T. Takahashi), T. Kanda, et al.Research communications in molecular pathology and pharmacology.112:159-1682002年
  • Effects of hormone replacement therapy on left ventricular hypertrophy and growth-promoting factors in hypertensive postmenopausal women(Y. Miya), T. Kanda, et al.Hypertension research : official journal of the Japanese Society of Hypertension.25: 153-1592002年
  • Differential effect of exercise on neutrophil apoptosis in patients with ischemic heart disease(H. Ogawara), T. Kanda, et al.Laboratory hematology : official publication of the International Society for Laboratory Hematology.8: 23-282002年
  • Clinical Research Activity Shown by Key Word ListingsJ. Yamakawa, T. Itoh, K. Kawaura, K. Kusaka, T. KandaKanazawa Ika Daigaku zasshi = Journal of Kanazawa Medical University. Links 27: 143-1462002年
  • Circulating leptin: a marker of health in female students(T. Kondo), T. Kanda, et al.The Journal of international medical research.30: 109-1152002年
  • Angiotensin-converting enzyme insertion/deletion polymorphism and polyneuropathy in type 2 diabetes without macroalbuminuria(H. Ito), T. Kanda, et al.The Journal of international medical research.30: 476-4822002年
  • Effect of interleukin-18 on viral myocarditis : enhancement of interferon-gamma and natural killer cell activityKANDA TsugiyasuJournal of Molecular and Cellular Cardiology2000年
  • リンパ球成熟のないウィルスにおけるウィルス性糖尿病の誘導神田 享勉ライフサイエンス1998年
  • Induction of virus-induced IDOM in virus resistant mice without lymphocyte maturationKANDA TsugiyasuLife Sciences1998年
  • Modification of viral myocarditis in mice by lnterleukin-6KANDA TsugiyasuCirculation Research1996年
  • Interleukin-8 as a sensitive marker of unstable coronary artery diseaseKANDA TsugiyasuThe American Journal of Cardiology1996年
  • Interleukin-6 secreted from human myxoma reduces murine viral myocarditisKANDA TsugiyasuLefe Sciences1996年
  • Myocardial uptake of an iodinated branched fatty acid analog assessing SPECT, may detect metabolic derangement of the myocardium in diabetic patients with coronary heart diseaseKANDA TsugiyasuCardiology1995年
  • False positive activated protein C sensitivity ratio caused by freezing and contamination of plasma with plateletsKANDA TsugiyasuTherapeutic Research1995年
  • Chronic effect of losartan in a murine model of dilated cardiomyopathy : Comparison with captoprilKANDA TsugiyasuJournal of Pharmacology and Experimental Therapeutics1995年
  • Myocardial beta-receptor and cardiac angiotensin alterations during the acute and chronic phases of viral myocarditisKANDA TsugiyasuEuropean Heart Journal1994年
  • Interleukin-6 and cardiacmytomaKANDA TsugiyasuAmerican Journal of Cardiology1994年
  • Holter monitoring as a noninvasive indicator of cardiac involvement in sarcoidosisKANDA TsugiyasuChest1994年
  • Dexamethasone inhibits production of interleukin-6 by cultured cardiac myxoma cellsKANDA TsugiyasuAmerican Heart Journal1994年
  • Myocardial atrial natriuretic factor gene expression after coronary ligation in ratsKANDA TsugiyasuExperimental and clinical Endocrinology1993年
  • Enhancement of myocardial damage and alteration of lymphocyte subsets in murine model of postpartum myocarditisKANDA TsugiyasuAmerican Journal of Cardiovascular1993年
  • The alpha and alpha 2 domains of H-2 class I molecules interact to form unique epitopesKANDA TsugiyasuImmunogenetics1987年
  • Physicians’ Resilience as a Positive Effect of COVID-19牛本知孝, 村坂憲史, 櫻井勝, 石﨑昌夫, 和藤幸弘, 神田享勉, 笠巻祐二JMA Journal6:365-3702023年10月
  • Orthogeriatric co-management at a regional core hospital as a new multidisciplinary approach in Japanese hip fracture operationToshihiro Higashikawa, Kenji Shigemoto, Manabu Moriyama, Daisuke Usuda, Masahiro Hangyou, Hiromi Inujima, Kakeru Nozaki, Miyako Yamaguchi, Kimiko Usuda, Osamu Iritani, Shigeto Morimoro, Takeshi Horii, Takeshi Nakahashi, Tadami Matsumoto, Toga Hirohisa, Shigeki Takashima, Tsugiyasu Kanda, Masashi Okuro, Takeshi SawaguchiJournal of Orthopaedic Science29:273-2772024年01月

書籍等出版物

  • 診断のための心血管系臨床検査の進め方
    心血管病学
    神田享勉
    朝倉書店 2005年07月
  • 基本に還る診療・医療面接
    循環plus
    神田享勉
    メディカルトリビューン 2004年

受賞

  • 1998年 第31回成人病研究助成受賞
    神田 享勉,
  • 1995年 公益信託臨床病理学研究振興基金研究奨励賞
    神田 享勉,

競争的資金

  • ストレスに対するRCAN1遺伝子の制御機構解明
    文部科学省:科学研究費 基盤研究(C)
    研究期間:2017年 - 2019年  
    代表者:神田享勉
  • 脳―心臓軸による心筋再生と治療;心筋内アディポネクチン発現誘導との関連
    文部科学省:科学研究費 基盤研究(C)
    研究期間:2009年 - 2011年  
    代表者:神田享勉
  • 心筋内アディポネクチン発現誘導による心筋再生治療
    文部科学省:科学研究費 基盤研究(C)
    研究期間:2007年 - 2008年  
    代表者:神田享勉
  • 心筋内アディポネクチンによる心筋再生機構と治療応用
    文部科学省:科学研究費 基盤研究(C)
    研究期間:2005年 - 2006年  
    代表者:神田享勉
  • レプチン・シグナル制御による心臓血管治療
    私学事業団:学術研究振興資金
    研究期間:2002年 - 2004年  
    代表者:神田享勉
  • レプチンの新しい心筋保護作用と治療応用
    文部科学省:科学研究費 基盤研究(C)
    研究期間:2000年 - 2001年  
    代表者:神田享勉