SASAGAWA Toshiyuki

FacultyDepartment of Obstetrics and Gynecology, Division of Gynecology and Obstetrics Research in Microbiology and Cancer Immunology

Researcher Profile & Settings


    Overview of research:
    Human papilllomavirus infection, host immunity and urogenital cancer, Development of cancer immune-therapy, Treatment of Obstet/ Gynecologic disorders with Chinese medicine.


  • Osaka University Graduate School Division of Medicine
  • Osaka University Faculty of Medicine


  • Ph.D in Medicine

Association Memberships

  • 1998American Association for Cancer Research member
  • 2004International Papillomavirus Society Board member
  • 1989Japanese Cancer Association member
  • 1983Japanese Society of Obstetrics and Gynecology Member
  • 20082015Japanese Society of Adolescentology Councilor
  • 2006Japanese Society of Sexually Transmitted Infection councilor
  • 2009The Japanese Society for Oriental Medicine member

Academic & Professional Experience

  • Jun. 1983Jun. 1986Toyonaka Municipal Hospital Medical Doctor for Obstetrics and Gynecology
  • Jul. 1987Mar. 1988Hospital of Institute for Microbial Disease in Osaka University Medical Doctor for Gynecology
  • Sep. 1992Dec. 1992Suita Municipal Hospital Medical Doctor for Obstetrics and Gynecology
  • Feb. 1993Jun. 1995Imperial Cancer Research Fund, Tumour Virus Group Reseracher

Research Activities

Published Papers

  • Human papillomavirus infection and pathogenesis in urothelial cells: a mini-review, (K.Shigehara), T.Sasagawa, M.Namiki, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.20:741-747Dec. 2014
  • Cytological evaluation using liquid-based cytology in the male urogenital tract infected with human papillomavirus, (K.Shigehara), T.Sasagawa, S.Kawaguchi, K.Nakashima, T.Nakashima, M.Shimamura, K.Furubayashi, M.Namiki, Diagnostic cytopathology.42:491-497Jun. 2014
  • HPV infection as an STI:a review of the prophylaxis and treatment of HPV-related diseases from an immunological point of view, T.Sasagawa, N.Yamaguchi, S.Fujita, H.Takagi, S.Makinoda25:27-362014
  • Detection of high-risk human papillomavirus subtypes in cervical glandular neoplasia by in situ hybridization., Z.Shang, H.Minato, T.Sasagawa, S.Nakada, E.Kinoshita, N.Kurose, T.Nojima, S.Makinoda, International journal of clinical and experimental pathology6:2168-2177Oct. 2013
  • Significance of Kampo, traditional Japanese medicine, in supportive care of cancer patients., J.Yamakawa, Y.Motoo, J.Moriya, M.Ogawa, H.Uenishi, S.Akazawa, T.Sasagawa, M.Nishio, J.Kobayashi, Evidence-based complementary and alternative medicine : eCAM.2013,746486;1-10Mar. 2013
  • Role of Kampo medicine in integrative cancer therapy., J.Yamakawa, Y.Motoo, J.Moriya, M.Ogawa, H.Uenishi, S.Akazawa, T.Sasagawa, M.Nishio, J.Kobayashi, Evidence-based complementary and alternative medicine : eCAM.2013:570848;1-6Mar. 2013
  • Prevalence of genital Mycoplasma, Ureaplasma, Gardnerella, and human papillomavirus in Japanese men with urethritis, and risk factors for detection of urethral human papillomavirus infection, (K.Shigehara), S.Kawaguchi, T.Sasagawa, K.Furubayashi, M.Shimamura, Y.Maeda, H.Konaka, A.Mizokami, E.Koh, M.Namiki, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.17:487-492Apr. 2011
  • Etiological role of human papillomavirus infection for inverted papilloma of the bladder, (K.Shigehara), T.Sasagawa, J.Doorbar, S.Kawaguchi, Y.Kobori, T.Nakashima, M.Shimamura, Y.Maeda, T.Miyagi, Y.Kitagawa, Y.Kadono, H.Konaka, A.Mizokami, E.Koh, M.Namiki, Journal of medical virology.83:277-285Feb. 2011
  • Oral and cervical human papillomavirus infection among female sex workers in Japan, (K.Matsushita), T.Sasagawa, M.Miyashita, A.Ishizaki, A.Morishita, N.Hosaka, K.Saikawa, S.Hoshina, X.Bi, H.Ichimura, Japanese journal of infectious diseases.64:34-39Jan. 2011
  • Etiologic role of human papillomavirus infection in bladder carcinoma, (K.Shigehara), T.Sasagawa, S.Kawaguchi, T.Nakashima, M.Shimamura, Y.Maeda, H.Konaka, A.Mizokami, E.Koh, M.Namiki, Cancer117:2067-20762010
  • Myeloperoxidase in blood neutrophils during normal and abnormal menstrual cycles in women of reproductive age, T.Shibata, J.Sakamoto, Y.Osaka, N.Neyatani, S.Fujita, Y.Oka, H.Takagi, H.Mori, H.Fujita, Y.Tanaka, T.Sasagawa, International Journal of Laboratory Hematology39:169-174Dec. 2016
  • Myeloperoxidase in blood neutrophils during normal and abnormal menstrual cycles in women ofreproductive age, T.Shibata J.Sakamoto Y.Osaka N.Neyatani S.Fujita Y.Oka T.akagi H.Mori H.Fujita Y.Tanaka T.Sasagawa, Int J Lab Hematol39:169-174Apr. 2017
  • Utility of 18F-fluorodeoxyglucose-positron emission tomography in the differential diagnosis of benign and malignant gynaecological tumours, H.Takagi, J.Sakamoto, Y.Osaka, T.Shibata, S.Fujita and T.Sasagawa, Journal of medical imaging and radiation oncology62:471-479Aug. 2018
  • Usefulness of the maximum standardized uptake value for the diagnosis and staging of patients with cervical cancer undergoing positron emission tomography/computed tomography, H.Takagi, J.Sakamoto, Y.Osaka, T.Shibata, S.Fujita, T.Sasagawa, Medicine97:e9856Feb. 2018
  • Association between 18F-fluorodeoxyglucose-PET/CT and grade of uterine endometrial carcinoma, H.Takagi, T.Sasagawa, T.Shibata, H.Minato, T.Takahashi, Taiwanese Journal of Obstetrics and Gynecology57:283-288Apr. 2018
  • Comparison of the digene hybrid capture 2 and Roche cobas 4800 HPV tests for detection of CIN2+ in a referral population in Japan, T.Sasagawa, T.Maehama, Y.Osaka, J.Sakamoto, T.Shibata, S.Fujita, M.Takakura, Journal of medical virology90:972-980May. 2018
  • Single type infection of human papillomavirus as a cause for high-grade cervical intraepithelial neoplasia and invasive cancer in Japan, J.Sakamoto, S.Kamiura, K.Okayama, M.Okodo, T.Shibata, Y.Osaka, S.Fujita, E.Takata, H.Takagi, M.Takakura, T.Sasagawa, Papillomavirus Res.6:46-51Dec. 2018
  • Malignant Transformation of an Ovarian Endometrioma during Endometriosis Treatment:A Case Report, H.Takagi, E.Takata, J.Sakamoto, S.Fujita, M.Takakura, T.Sasagawa, Case reports in obstetrics and gynecology4:6210172Sep. 2018
  • Uniplex E6/E7 PCR method detecting E6 or E7 genes in 39 human papillomavirus types, Mitsuaki Okodo, Kaori Okayama, Koji Teruya, Toshiyuki Sasagawa, Journal of medical virology90:981-988May. 2018
  • The promise of combining cancer vaccine and checkpoint blockade for treating HPV-related cancer, Takeo Shibata, Benjamin J Lieblong, Toshiyuki Sasagawa, Mayumi Nakagawa, Cancer Treatment Reviews78:8-16Aug. 2019
  • Long-term treatment of endometriosis with dienogest for up to five years, Takagi H, Sakamoto J, Sasagawa T, Clinical and Experimental Obstetrics & Gynecology46:398-402Jun. 2019
  • Adenosquamous carcinoma of the uterine cervix displaying tumor-associated tissue eosinophilia, Nozomu Kurose, Seiya Mizuguchi, Yoshiiku Ohkanemasa, Manabu Yamashita, Mariko Nakano, Xin Guo, Akane Aikawa, Satoko Nakada, Toshiyuki Sasagawa, Sohsuke Yamada, SAGE Open Medical Case Reports7:2050313X19828235Feb. 2019

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