MIWA Takaki

■FacultyDepartment of Otorhinolaryngology
■PositionProfessor

Researcher Profile & Settings

Research

    Overview of research:
    Basic and clinical research for olfactory disorders

Education

  • Kanazawa University Graduate School
  • Toyama Medical and Pharmaceutical University

Degree

  • Ph.D in Medicine

Research Activities

Published Papers

  • International consensus statement on allergy and rhinology: Olfaction, Patel ZM, Holbrook EH, Turner JH, Adappa ND, Albers MW, Altundag A, Appenzeller S, Costanzo RM, Croy I, Davis GE, Dehgani-Mobaraki P, Doty RL, Duffy VB, Goldstein BJ, Gudis DA, Haehner A, Higgins TS, Hopkins C, Huart C, Hummel T, Jitaroon K, Kern RC, Khanwalkar AR, Kobayashi M, Kondo K, Lane AP, Lechner M, Leopold DA, Levy JM, Marmura MJ, Mclelland L, Miwa T, Moberg PJ, Mueller CA, Nigwekar SU, O'Brien EK, Paunescu TG, Pellegrino R, Philpott C, Pinto JM, Reiter ER, Roalf DR, Rowan NR, Schlosser RJ, Schwob J, Seiden AM, Smith TL, Soler ZM, Sowerby L, Tan BK, Thamboo A, Wrobel B, Yan CH, International Forum of Allergy & Rhinology, 12:325-680, Apr. 2022
  • A clinical survey on patients with taste disorders in Japan: A comparative study, ｢Tomomi Nin｣, Makoto Tanaka, Kohei Nishida, Junpei Yamamoto, Takaki Miwa, 49:797-804, Jan. 2022
  • Olfactory-cognitive index distinguishes involvement of frontal lobe shrinkage, as in sarcopenia from shrinkage of medial temporal areas, and global brain, as in Kihon Checklist frailty/dependence, in older adults with progression of normal cognition to Alzheimer's disease, Osamu Iritani, Tazuo Okuno, Takaki Miwa, Hyuma Makizako, Fumino Okutani, Tetsuo Kashibayashi, Kumiko Suzuki, Hideo Hara, Eri Mori, Shusaku Omoto, Hirokazu Suzuki, Minori Shibata, Hiroaki Adachi, Kenji Kondo, Yumi Umeda-Kameyama, Kumie Kodera, Shigeto Morimoto , Geriatrics & Gerontology International, 21:291-298, Mar. 2021
  • Efficacy and Safety of Polaprezinc (Zinc Compound) on Zinc Deficiency: A Systematic Review and Dose–Response Meta-Analysis of Randomized Clinical Trials Using Individual Patient Data, Kei Furihata, Masaru Tsuchikawa, Takaki Miwa, Yuji Naito, Koji Oba, Masafumi Sakagami, Nutrients, 12:1128, Apr. 2020
  • Relationship between olfactory disturbance after acute ischemic stroke and latent thalamic hypoperfusion, (Kazuhiro Okamoto), Hideaki Shiga, Hisako Nakamura, Makoto Matsui, Takaki Miwa, Chemical Senses, 45:111-118, Feb. 2020
  • The impact of ovariectomy on olfactory neuron regeneration in mice, Kentaro Yamada, Hideaki Shiga, Takuya Noda, Masayuki Harita, Tomoko Ishikura, Yukari Nakamura, Toshihisa Hatta, Hiromi Sakata-Haga, Hiroki Shimada, Takaki Miwa, Chemical Senses, 45:203-209, Feb. 2020
  • Thallium-201 imaging in intact olfactory sensory neurons with reduced pre-synaptic inhibition in vivo, Hideaki Shiga, Hiroshi Wakabayashi, Kohshin Washiyama, Tomohiro Noguchi, Tomo Hiromasa, Sadaharu Miyazono, Masami Kumai, Kazuma Ogawa, Junichi Taki, Seigo Kinuya, Takaki Miwa, Moleculer Neurobiology, 57:4989-4999, Aug. 2020
  • Clinical practice guidelines for the management of olfactory dysfunction - Secondary publication, Miwa T, Ikeda K, Ishibashi T, Kobayashi M, Kondo K, Matsuwaki Y, Ogawa T, Shiga H, Suzuki M, Tsuzuki K, Furuta A, Motoo Y, Fujieda S, Kurono Y, Auris Nasus Larynx, 46:653-662, Oct. 2019
  • Effects of tokishakuyakusan on regeneration of murine olfactory neurons in vivo and in vitro, Takuya Noda, Hideaki Shiga, Kentaro Yamada, Masayuki Harita, Yukari Nakamura, Tomoko Ishikura, Masami Kumai, Zenji Kawakami, Atsushi Kaneko, Toshihisa Hatta, Hiromi Sakata-Haga, Hiroki Shimada, Takaki Miwa, Chemical Senses, 44:327-338, May 2019
  • Association of olfactory impairment with indexes of sarcopenia and frailty in community-dwelling older adults, Harita M, Miwa T, Shiga H, Yamada K, Sugiyama E, Okabe Y, Miyake Y, Okuno T, Iritani O, Morimoto S, Geriatrics & Gerontology International, 19:384-391, May 2019
  • Nasal thallium-201 uptake in patients with parosmia with and without hyposmia after upper respiratory tract infection, Shiga H, Okuda K, Taki J, Watanabe N, Tonami H, Kinuya S, Miwa T, International forum of allergy & rhinology, 9:1252-1256, Nov. 2019
  • Estimate of swallowing ability of acute stroke patience with estimate model of Fujishima dysphagia gradin, K.Okamoto, K.Kyoda, M.Tsubokawa, K.Irie, T.Miwa and K.Kagechika, Deglutition, 7:273-278, Sep. 2018
  • Olfactory function tests, Takaaki Miwa, Journal of Japan Association on Odor Environment, 49:363-369, Nov. 2018
  • Sinonasal NUT carcinoma: clinicopathological and cytogenetic analysis with autopsy findings., H Minato, E Kobayashi, S Nakada, N Kurose, M Tanaka, Y Tanaka, S Suzuki, F Tanioka, Y Saikawa, T Miwa, T Nojima, HUMAN PATHOLOGY, 71:157-165, Jan. 2018
  • A case of intestinal-type adenocarcinoma treated with skull base surgery after induction chemotherapy, Noda Takuya, Nakamura Yukari, Miwa Takaki, Shimode Yuzo, Tsuji Hiroyuki, Akai Takuya, Yamashita Masanobu, JOURNAL OF JAPAN SOCIETY FOR HEAD AND NECK SURGERY, 26:419-423, 2016
  • Position paper on olfactory dysfunction, (T. Hummel), K.L. Whitcroft, P. Andrews, A. Altundag, C. Cinghi, R.M. Costanzo, M. Damm, J. Frasnelli, H. Gudziol, N. Gupta, A. Haehner, E. Holbrook, S.C. Hong, D. Hornung, K.B. Hüttenbrink, R. Kamel, M. Kobayashi, I. Konstantinidis, B.N. Landis, D.A. Leopold, A. Macchi, T. Miwa, R. Moesges, J. Mullol, C.A. Mueller, G. Ottaviano, G.C. Passali, C. Philpott, J.M. Pinto, V.J. Ramakrishnan, P. Rombaux, Y. Roth, R.A. Schlosser, B. Shu, G. Soler, P. Stjärne, B.A. Stuck, J. Vodicka, A. Welge-Luessen, RHINOLOGY, 54:1-30, Mar. 2017
  • Prognostic value of olfactory nerve damage measured with thallium-based olfactory imaging in patients with idiopathic olfactory dysfunction., Shiga Hideaki;Taki Junichi;Okuda Koichi;Watanabe Naoto;Tonami Hisao;Nakagawa Hideaki;Kinuya Seigo;Miwa Takaki, Scientific reports, 7:1, 2017
  • Changes in smell and taste function in the elderly, T.Miwa, J.Yamamoto, K.Teraguchi, Y.Kinoshita, K.Yamada, T.Noda, M.Harita, H.Shiga, E.Sugiyama, K.Ono, Chemical Senses, 40:261-261, Mar. 2015
  • Nasal drug delivery facilitates molecular imaging of olfactory disorders., H.Shiga, T.Miwa, Nihon Bika Gakkai Kaishi (Japanese Journal of Rhinology), 54:47-51, 2015
  • Implementation report of screening investigation of dementia for inhabitants of rural areas in Himi,Toyama, Y.Matsuda, S.Takemoto, R.Hashimoto, A.Tamai, T.Kanda, M.Ishizaki, T.Miwa, S.Morimoto, O.Kitamura, Y.Kawasaki, 39:67-74, Dec. 2014
  • A case of specfic language impairment with kana reading difficulty, N.Yamazaki, A.Notoya, Y.Suzuka, T.Miwa, 35:257-262, Dec. 2014
  • Olfactory function test-present status and future prospects-, T.Miwa, 107:849-857, Nov. 2014
  • Reduced nasal transport of insulin-like growth factor-1 to the mouse cerebrum with olfactory bulb resection., H.Shiga, M.Nagaoka, K.Washiyama, J.Yamamoto, K.Yamada, T.Noda, M.Harita, R.Amano, T.Miwa, Chemical senses., 39:595-599, Sep. 2014
  • Fractional change in apparent diffusion coefficient as an imaging biomarker for predicting treatment response in head and neck cancer treated with chemoradiotherapy, M.Matoba, H.Tsuji, Y.Shimode, I.Toyota, Y.Kuginuki, T.Miwa, H.Tonami, AJNR. American journal of neuroradiology., 35:379-385, Feb. 2014
  • Combinations of two odorants of smell identification test for screening of olfactory impairment., H.Shiga, J.Yamamoto, M.Kitamura, H.Nakagawa, T.Matsubasa, A.Seo, T.Miwa, Auris, nasus, larynx., 41:523-527, 2014
  • Assessment of treatment effect for acromegaly with sleep disordered breathing., A.Sakai, H.Toga, O.Tachibana, T.Miwa, 116:612-618, 2013
  • Internal dosimetry for nasal thallium-201 administration., (S.Kinase), K.Washiyama, H.Shiga, J.Taki, Y.Nakanishi, K.Koshida, T.Miwa, S.Kinuya, R.Amano, KEK Proceedings, 7:35-40, 2012
  • Biological safety of nasal thallium-201 administration: a preclinical study for olfacto-scintigraphy, (K.Washiyama), H.Shiga, K.Hirota, A.Tsuchida, J.Yamamoto, S.Yagi, T.Yoshizaki, M.Furukawa, R.Amano, T.Miwa, Journal of radiation research, 52:450-455, May 2011
  • Epidemiological analysis of nasopharyngeal carcinoma in the central region of Japan during the period from 1996 to 2005., (Y.Kimura), D.Suzuki, T.Tokunaga, T.Takabayashi, T.Yamada, N.Wakisaka, T.Yoshizaki, H.Murata, T.Miwa, H.Shoujaku, Y.Watanabe, N.Yamada, Y.Ito, A.Yuta, K.Takeuchi, S.Hosokawa, H.Mineta, Y.Hasegawa, Y.Fujimoto, T.Nakashima, S.Fujieda, Auris, nasus, larynx., 38:244-249, Apr. 2011
  • Efficacy of diffusion-weighted MR imaging and PET/CT for predicting and detecting early response to chemoradiation therapy squamous cell carcinoma in the head and neck, M.Matoba, I.Toyota, Y.Kuginuki, H.Tonami, T.Miyazawa, Y.Shimode, H.Tsuji, T.Miwa, 31:115-123, 2011
  • Recent　progress of basic research on olfactory reception and the pathology of olfactory disorders, T.Miwa, 103:1073-1081, Dec. 2010
  • Evaluation of the olfactory nerve transport function by SPECT-MRI fusion image with nasal thallium-201 administration, H.Shiga, J.Taki, M.Yamada, K.Washiyama, R.Amano, Y.Matsuura, O.Matsui, S.Tatsutomi, S.Yagi, A.Tsuchida, T.Yoshizaki, M.Furukawa, S.Kinuya, T.Miwa, Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, 13:1262-1266, Dec. 2010
  • A case of recurrent frontal sinusitis -The usefulness of Mini-Trephine-, K.Yamada, H.Shiga, J.Yamamoto, T.Miwa, 53:327-330, Oct. 2010
  • Use of thallium transport to visualize functional olfactory nerve regeneration in vivo, H.Shiga, K.Washiyama, K.Hirota, R.Amano, M.Furukawa, T.Miwa, Rhinology, 47:460-464, Dec. 2009
  • Olfactory Nerve Imaging with SPECT/CT in Rats, H.Shiga, K.Washiyama, K.Ogawa, H.Yamaguchi, Y.Magata, R.Amano, M.Furukawa, T.Miwa, 48：138-141, Aug. 2009
  • Usefulness of curry odorant of odor stick identification test for Japanese in olfactory impairment screening, H.Shiga, H.Toda, T.Kobayakawa, S.Saito, K.Hirota, T.Tsukatani, M.Furukawa, T.Miwa, Acta oto-laryngologica., 129(Suppl.562):91-94, Jun. 2009
  • Olfactory nerve regeneration and molecular imaging, H.Shiga, T.Miwa, 16 (1) : 11-15, Apr. 2009
  • Odor detection ability and thallium-201 transport in the olfactory nerve of traumatic olfactory-impaired mice., H.Shiga, Y.Kinoshita, K.Washiyama, R.Amano, K.Hirota, T.Tsukatani, M.Furukawa, T.Miwa, Chemical senses., 33: 633-637, Sep. 2008
  • Thallium transport and the evaluation of olfactory nerve connectivity between the nasal cavity and olfactory bulb., (Y.Kinoshita), H.Shiga, K.Washiyama, D.Ogawa, R.Amano, M.Ito, T.Tsukatani, M.Furukawa, T.Miwa, Chemical senses., 33: 73-78, Jan. 2008
  • Olfactory and taste dysfunctions caused by COVID-19: a nationwide study, Takaki MIwa, Eri Mori, Rumi Sekine, Yurika Kimura, Masayoshi Kobayashi, Hideaki Shiga, Kenzo Tsuzuki, Motohiko Suzuki, Kenji Kondo, Isao Suzaki, Go Inokuchi, Tsunemasa Aiba, Kyoko Chujo, Sayaka Yagi-Nakanishi, Toshiaki Tsukatani, Hiroki Nakanishi, Muneko Nishijyo, Yoshitsugu Iinuma, Akihito Yokoyama, Rhinology, 61:552-560, Jan. 2023
  • Olfactory regeneration with nasally administered murine adipose-derived stem cells in olfactory epithelium damaged mice, Tomoko Ishikura, Hideaki Shiga, Yuka Nakamura, Takako Kanitani, Yasuhito Ishigaki and Takaki MIwa, Cells, Cells 2023:765, Feb. 2023