UWADA Junsuke

FacultyDepartment of Pharmacology
PositionSenior Assistant Professor

Research Activities

Published Papers

  • Evaluation of radiolabeled acetylcholine synthesis and release in rat striatum., Muramatsu I, Uwada J, Chihara K, Sada K, Wang MH, Yazawa T, Taniguchi T, Ishibashi T, Masuoka T., Journal of Neurochemistry160:342-355Feb. 2022
  • Voluntary wheel-running activities ameliorate depressive-like behaviors in mouse dry eye model, Katsuya Nakano, Hitomi Nakazawa, Qiang He, Junsuke Uwada, Takeshi Kiyoi, Takaharu Ishibashi, Takayoshi Masuoka16:925128Sep. 2022
  • Evaluation of radiolabeled acetylcholine synthesis and release in rat striatum, Ikunobu Muramatsu, Junsuke Uwada, Kazuyasu Chihara, Kiyonao Sada, Mao-Hsien Wang, Takashi Yazawa, Takanobu Taniguchi, Takaharu Ishibashi, Takayoshi Masuoka160:342-355Feb. 2022
  • 11-Ketotestosterone is a major androgen produced in porcine adrenal glands and testes., Yazawa T, Sato T, Nemoto T, Nagata S, Imamichi Y, Kitano T, Sekiguchi T, Uwada J, Islam MS, Mikami D, Nakajima I, Takahashi S, Khan MRI, Suzuki N, Umezawa A, Ida T, The Journal of Steroid Biochemistry and Molecular Biology210:105847Jan. 2021
  • Profiles of 5α-Reduced Androgens in Humans and Eels: 5α-Dihydrotestosterone and 11-Ketodihydrotestosterone Are Active Androgens Produced in Eel Gonads, Yazawa T, Inaba H, Imamichi Y, Sekiguchi T, Uwada J, Islam MS, Orisaka M, Mikami D, Ida T, Sato T, Miyashiro Y, Takahashi S, Khan MRI, Suzuki N, Umezawa A, Kitano T, Frontiers in Endocrinology12:657360Mar. 2021
  • Pleiotropic effects of probenecid on three-dimensional cultures of prostate cancer cells, Uwada J, Mukai S, Terada N, Nakazawa H, Islam MS, Nagai T, Fujii M, Yamasaki K, Taniguchi T, Kamoto T, Yazawa T, Life Sciences1:119554Aug. 2021
  • Analyses of Molecular Characteristics and Enzymatic Activities of Ovine HSD17B3., Islam MS, Uwada J, Hayashi J, Kikuya KI, Muranishi Y, Watanabe H, Yaegashi K, Hasegawa K, Ida T, Sato T, Imamichi Y, Kitano T, Miyashiro Y, Khan RI, Takahashi S, Umezawa A, Suzuki N, Sekiguchi T, Yazawa T., Animals11:2876Sep. 2021
  • Evaluation of 17β-hydroxysteroid dehydrogenase activity using androgen receptor-mediated transactivation., Yazawa T, Imamichi Y, Uwada J, Sekiguchi T, Mikami D, Kitano T, Ida T, Sato T, Nemoto T, Nagata S, Islam Khan MR, Takahashi S, Ushikubi F, Suzuki N, Umezawa A, Taniguchi T., The Journal of Steroid Biochemistry and Molecular Biology196:105493Feb. 2020
  • β-Hydroxybutyrate enhances the cytotoxic effect of cisplatin via the inhibition of HDAC/survivin axis in human hepatocellular carcinoma cells., Mikami D, Kobayashi M, Uwada J, Yazawa T, Kamiyama K, Nishimori K, Nishikawa Y, Nishikawa S, Yokoi S, Taniguchi T, Iwano M., Journal of Pharmacological Sciences142:1-8Jan. 2020
  • Short-chain fatty acid mitigates adenine-induced chronic kidney disease via FFA2 and FFA3 pathways., Mikami D, Kobayashi M, Uwada J, Yazawa T, Kamiyama K, Nishimori K, Nishikawa Y, Nishikawa S, Yokoi S, Kimura H, Kimura I, Taniguchi T, Iwano M., Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids1865:158666Jan. 2020
  • AR420626, a selective agonist of GPR41/FFA3, suppresses growth of hepatocellular carcinoma cells by inducing apoptosis via HDAC inhibition., Mikami D, Kobayashi M, Uwada J, Yazawa T, Kamiyama K, Nishimori K, Nishikawa Y, Nishikawa S, Yokoi S, Taniguchi T, Iwano M., Therapeutic Advances in Medical Oncology12:1758835920913432Mar. 2020
  • PNU-120596, a positive allosteric modulator of α7 nicotinic acetylcholine receptor, directly inhibits p38 MAPK., Uwada J, Nakazawa H, Mikami D, Islam MS, Muramatsu I, Taniguchi T, Yazawa T, Biochemical Pharmacology182:114297Dec. 2020
  • Augmentation of Endogenous Acetylcholine Uptake and Cholinergic Facilitation of Hippocampal Long-Term Potentiation by Acetylcholinesterase Inhibition., Masuoka T, Uwada J, Kudo M, Yoshiki H, Yamashita Y, Taniguchi T, Nishio M, Ishibashi T, Muramatsu I., Neuroscience404:39-47Apr. 2019
  • β-Hydroxybutyrate, a ketone body, reduces the cytotoxic effect of cisplatin via activation of HDAC5 in human renal cortical epithelial cells., Mikami D, Kobayashi M, Uwada J, Yazawa T, Kamiyama K, Nishimori K, Nishikawa Y, Morikawa Y, Yokoi S, Takahashi N, Kasuno K, Taniguchi T, Iwano M, Life Sciences222:125-132Apr. 2019
  • Novel regulatory systems for acetylcholine release in rat striatum and anti-Alzheimer's disease drugs., Muramatsu I, Uwada J, Yoshiki H, Sada K, Lee KS, Yazawa T, Taniguchi T, Nishio M, Ishibashi T, Masuoka T., Journal of Neurochemistry149:605-623Jun. 2019
  • Transcriptional Regulation of Ovarian Steroidogenic Genes: Recent Findings Obtained from Stem Cell-Derived Steroidogenic Cells., Yazawa T, Imamichi Y, Sekiguchi T, Miyamoto K, Uwada J, Khan MRI, Suzuki N, Umezawa A, Taniguchi T, BioMed Research International2019:8973076Apr. 2019
  • Cyclooxygenase-2 is acutely induced by CCAAT/enhancer-binding protein β to produce prostaglandin E 2 and F 2α following gonadotropin stimulation in Leydig cells., Yazawa T, Imamichi Y, Yuhki KI, Uwada J, Mikami D, Shimada M, Miyamoto K, Kitano T, Takahashi S, Sekiguchi T, Suzuki N, Rafiqul Islam Khan M, Ushikubi F, Umezawa A, Taniguchi T., Molecular Reproduction and Development86:786-797Jul. 2019
  • Store-operated calcium entry (SOCE) contributes to phosphorylation of p38 MAPK and suppression of TNF-α signalling in the intestinal epithelial cells., Uwada J, Yazawa T, Nakazawa H, Mikami D, Krug SM, Fromm M, Sada K, Muramatsu I, Taniguchi T.63:109358Nov. 2019