Suppression of murine autoimmune myocarditis achieved with direct renin inhibition, (Takamura C), Suzuki J, Ogawa M, Watanabe R, Tada Y, Maejima Y, Akazawa H, Komuro I, Isobe M, Journal of Cardiology, 68:253-260, 2016年09月
Cardiac arrest triggered by subepicardial aneurysm without cardiac rupture, (Hasumi E), Fujiu K, Imamura T, Iwata H, Sawaki D, Hosoya Y, Ando J, Kojima T, Shimizu Y, Oguri G, Matsubara T, Hatano M, Akazawa H, Watanabe M, Ono M, Komuro I, Circulation Journal, 80:538-540, 2016年01月
Direct left atrial ICE imaging guided ablation for atrial fibrillation without employing contrast medium, (Matsubara TJ), Fujiu K, Asada K, Kojima T, Makimoto H, Yamagata K, Shimizu Y, Hasumi E, Hatano M, Akazawa H, Komuro I, International Journal of Cardiology, 203:733-739, 2016年01月
Current therapies and investigational drugs for peripheral arterial disease, (Suzuki J), Shimamura M, Suda H, Wakayama K, Kumagai H, Ikeda Y, Akazawa H, Isobe M, Komuro I, Morishita R, Hypertension Research, 39:183-191, 2016年04月
Angiotensin II receptor blocker irbesartan attenuates cardiac dysfunction induced by myocardial infarction in the presence of renal failure, (Watanabe R), Suzuki J, Wakayama K, Kumagai H, Ikeda Y, Akazawa H, Komuro I, Isobe M, Hypertension Research, 39:237-244, 2016年04月
Cacao polyphenols ameliorate autoimmune myocarditis in mice, (Zempo H), Suzuki J, Watanabe R, Wakayama K, Kumagai H, Ikeda Y, Akazawa H, Komuro I, Isobe M, Hypertension Research, 39:203-209, 2016年04月
A case of multiple coronary artery-left ventricular microfistulae complicated with hepatic arteriovenous fistulae, (Niwa R), Hasumi E, Fujiu K, Uehara M, Nitta D, Hatano M, Akazawa H, Watanabe M, Komuro I, International Heart Journal, 57:123-126, 2016年01月
Understanding vascular diseases: Lessons from premature aging syndromes, (Ikeda Y), Kumagai H, Motozawa Y, Suzuki J, Akazawa H, Komuro I, Canadian Journal of Cardiology, 32:650-658, 2016年05月
Porphyromonas gingivalis, a periodontal pathogen, enhances myocardial vulnerability, thereby promoting post-infarct cardiac rupture, (Shiheido Y), Maejima Y, Suzuki J, Aoyama N, Kaneko M, Watanabe R, Sakamaki Y, Wakayama K, Ikeda Y, Akazawa H, Ichinose S, Komuro I, Izumi Y, Isobe M, Journal of Molecular and Cellular Cardiology, 99:123-137, 2016年10月
Activation of endothelial β-catenin signaling induces heart failure, (Nakagawa A), Naito AT, Sumida T, Nomura S, Shibamoto M, Higo T, Okada K, Sakai T, Hashimoto A, Kuramoto Y, Oka T, Lee JK, Harada M, Ueda K, Shiojima I, Limbourg FP, Adams RH, Noda T, Sakata Y, Akazawa H, Komuro I, Scientific Reports, 6:25009, 2016年05月
Pathophysiology and management of cardiovascular manifestations in Marfan and Loeys-Dietz syndromes, (Takeda N), Yagi H, Hara H, Fujiwara T, Fujita D, Nawata K, Inuzuka R, Taniguchi Y, Harada M, Toko H, Akazawa H, Komuro I, International Heart Journal, 57:271-277, 2016年05月
Toll-like receptor 4 signaling plays a critical role in Porphyromonas gingivalis accelerated neointimal formation after arterial injury in mice, (Kobayashi N), Suzuki J, Aoyama N, Sato H, Akimoto S, Wakayama K, Kumagai H, Ikeda Y, Akazawa H, Komuro I, Izumi Y, Isobe M, Hypertension Research, 39:717-722, 2016年10月
Leukemia inhibitory factor enhances endogenous cardiomyocyte regeneration after myocardial infarction, (Kanda M), Nagai T, Takahashi T, Liu ML, Kondou N, Naito AT, Akazawa H, Sashida G, Iwama A, Komuro I, Kobayashi Y, PLoS One, 11:e0156562, 2016年05月
Periodontitis may deteriorate sinus of Valsalva dilatation in Marfan syndrome patients, (Suzuki J), Imai Y, Aoki M, Fujita D, Takeda N, Aoyama N, Wakayama K, Ikeda Y, Kumagai M, Akazawa H, Izumi Y, Isoba M, Komuro I, Hirata Y, International Heart Journal, 57:456-460, 2016年07月
Roles of renin-angiotensin system and Wnt pathway in aging-related phenotypes, (Kamo T), Akazawa H #, Suzuki J, Komuro I, Inflammation and Regeneration, 36:12, 2016年08月
Heart failure complicated by alveolar hemorrhage due to vascular collapse and amyloid deposits in wild-type transthyretin amyloidosis, (Kido Y), Takahashi M, Fukuma N, Kawata T, Tanaka A, Hayashi A, Shibahara J, Daimon M, Morita H, Akazawa H, Komuro I, Cardiology, 135:216-220, 2016年08月
A periodontal pathogen Porphyromonas gingivalis deteriorates isoproterenol-induced myocardial remodeling in mice, (Sato H), Suzuki J, Aoyama N, Watanabe R, Kaneko M, Shiheido Y, Yoshida Y, Wakayama K, Kumagai H, Ikeda Y, Akazawa H, Komuro I, Isobe M, Izumi Y, Hypertension Research, 40:35-40, 2017年01月
An EP4 receptor agonist inhibits cardiac fibrosis through activation of PKA signaling in hypertrophied heart, (Wang Q), Oka T, Yamagami K, Lee JK, Akazawa H, Naito AT, Yasui T, Ishizu T, Nakaoka Y, Sakata Y, Komuro I, International Heart Journal, 58:107-114, 2017年02月
Periodontitis and myocardial hypertrophy, (Suzuki J), Sato H, Kaneko M, Yoshida Y, Aoyama N, Akimoto S, Wakayama K, Kumagai H, Ikeda Y, Akazawa H, Izumi Y, Isobe M, Komuro I, Hypertension Research, 40:324-328, 2017年04月
Correct diagnosis of wild-type transthyretin-related amyloidosis followed by the introduction of a novel therapy in a patient with cardiac wall thickening of unknown cause, (Sawada N), Nakayama A, Takahashi M, Tanaka M, Morita H, Akazawa H, Komuro I, International Heart Journal, 58:147-150, 2017年02月
Cardiac sarcoidosis diagnosed by incidental lymph node biopsy, (Matsuda J), Fujiu K, Roh S, Tajima M, Maki H, Kojima T, Ushiku T, Nawata K, Takeda N, Watanabe M, Akazawa H, Komuro I, International Heart Journal, 58:140-143, 2017年02月
A peptide vaccine targeting angiotensin II attenuates the cardiac dysfunction induced by myocardial infarction, (Watanabe R), Suzuki J, Wakayama K, Maejima Y, Shimamura M, Koriyama H, Nakagami H, Kumagai H, Ikeda Y, Akazawa H, Morishita R, Komuro I, Isobe M, Scientific Reports, 7:43920, 2017年03月
Dysbiosis and compositional alterations with aging in the gut microbiota of patients with heart failure, (Kamo T), Akazawa H #, Suda W, Saga-Kamo A, Shimizu Y, Yagi H, Liu Q, Nomura S, Naito AT, Takeda N, Harada M, Toko H, Kumagai H, Ikeda Y, Takimoto E, Suzuki J, Honda K, Morita H, Hattori M, Komuro I, PLoS One, 12:e0174099, 2017年03月
Angiotensin II peptide vaccine protects brain through reducing oxidative stress, (Wakayama K), Shimamura M, Suzuki J, Watanabe R, Koriyama H, Akazawa H, Nakagami H, Mochizuki H, Isobe M, Morishita R, Stroke, 48:1362-1368, 2017年05月
DNA single-strand break-induced DNA damage response causes heart failure, (Higo T), Naito AT, Sumida T, Shibamoto M, Okada K, Nomura S, Nakagawa A, Yamaguchi T, Sakai T, Hashimoto A, Kuramoto Y, Ito M, Hikoso S, Akazawa H, Lee JK, Shiojima I, Mckinnon PJ, Sakata Y, Komuro I, Nature Communications, 8:15104, 2017年04月
MicroRNA-99a: A new kid on the block for cardioprotection, (Liu Q), Akazawa H, International Heart Journal, 58:310-312, 2017年05月
Novel Concept of a Heart-Gut Axis in the Pathophysiology of Heart Failure, (Kamo T), Akazawa H, Suzuki JI, Komuro I, Korean Circulation Journal, 47:663-669, 2017年09月
Periodontitis deteriorates peripheral arterial disease in Japanese population via enhanced systemic inflammation, (Aoyama N), Suzuki JI, Kobayashi N, Hanatani T, Ashigaki N, Yoshida A, Shiheido Y, Sato H, Kumagai H, Ikeda Y, Akazawa H, Komuro I, Izumi Y, Isobe M, Heart and Vessels, 32:1314-1319, 2017年11月
Detrimental effects of specific periodontopathic bacterial infection on tachyarrhythmia compared to bradyarrhythmia, (Aoyama N), Suzuki J, Kobayashi N, Hanatani T, Ashigaki A, Yoshida A, Shiheido Y, Sato H, Kumagai H, Ikeda Y, Akazawa H, Komuro I, Minabe M, Izumi Y, Isobe M, BMC Cardiovascular Disorders, 17:267, 2017年10月
Cost-effectiveness analysis of cardiovascular disease treatment in Japan, (Kodera S), Kiyosue A, Ando J, Akazawa H, Morita H, Watanabe M, Komuro I, International Heart Journal, 58:847-852, 2017年12月
Specific periodontopathic bacterial infection affects hypertension in male cardiovascular disease patients, (Aoyama N), Suzuki JI, Kumagai H, Ikeda Y, Akazawa H, Komuro I, Minabe M, Izumi Y, Isobe M, Heart and Vessels, 33:198-204, 2018年02月
Japanese cardiovascular disease patients with diabetes mellitus suffer increased tooth loss in comparison to those without diabetes mellitus - a cross-sectional study, (Aoyama N), Suzuki JI, Kobayashi N, Hanatani T, Ashigaki N, Yoshida A, Shiehido Y, Sato H, Kumagai H, Ikeda Y, Akazawa H, Komuro I, Minabe M, Izumi Y, Isobe M, Internal Medicine, 57:777-782, 2018年03月
Coronary artery aneurysm caused by a stent fracture, (Oshima T), Minatsuki S, Myojo M, Kodera S, Nawata K, Ando J, Akazawa H, Watanabe M, Ono M, Komuro I, International Heart Journal, 59:203-208, 2018年01月
Distinct variants affecting differential splicing of TGFBR1 exon 5 cause either Loeys-Dietz syndrome or multiple self-healing squamous epithelioma, (Fujiwara T), Takeda N, Hara H, Morita H, Kishihara J, Inuzuka R, Yagi, H, Maemura S, Toko H, Harada M, Ikeda Y, Kumagai H, Nomura S, Takimoto E, Akazawa H, Ako J, Komuro I, European Journal of Human Genetics, 26:1151-1158, 2018年08月
Impact of pathogenic FBN1 variant types on the progression of aortic disease in patients with Marfan syndrome, (Takeda N), Inuzuka R, Maemura S, Morita H, Nawata K, Fujita D, Taniguchi Y, Yamauchi H, Yagi H, Kato M, Nishimura H, Hirata Y, Ikeda Y, Kumagai H, Amiya E, Hara H, Fujiwara T, Akazawa H, Suzuki JI, Imai Y, Nagai R, Takamoto S, Hirata Y, Ono M, Komuro I, Circulation: Genomic and Precision Medicine, 11:e002058, 2018年06月
Periodontitis and diabetes mellitus: Be true to your teeth, (Akazawa H), International Heart Journal, 59:680-682, 2018年07月
A novel bioabsorbable sheet that delivers NF-κB decoy oligonucleotide restrains abdominal aortic aneurysm development in rats, (Akimoto S), Suzuki J, Aoyama N, Ikeuchi R, Watanabe H, Tsujimoto H, Wakayama K, Kumagai H, Ikeda Y, Akazawa H, Komuro I, International Heart Journal, 59:1134-1141, 2018年09月
MicroRNAs as Biomarkers for Cardiac Sarcoidosis: No Matter How Small, (Umei M), Akazawa H, Journal of Cardiology, 72:449-451, 2018年12月
Activated β-catenin in Foxp3(+) regulatory T cells links inflammatory environments to autoimmunity, (Sumida T), Lincoln MR, Ukeje CM, Rodriguez DM, Akazawa H, Noda T, Naito AT, Komuro I, Dominguez-Villar M, Hafler DA, Nature Immunology, 19:1391-1402, 2018年12月
Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure, (Nomura S), Satoh M, Fujita T, Higo T, Sumida T, Ko T, Yamaguchi T, Tobita T, Naito AT, Ito M, Fujita K, Harada M, Toko H, Kobayashi Y, Ito K, Takimoto E, Akazawa H, Morita H, Aburatani H Komuro I, Nature Communications, 9:4435, 2018年10月
Discovery of a Small Molecule to Increase Cardiomyocytes and Protect the Heart After Ischemic Injury, (Hara H), Takeda N, Kondo M, Kubota M, Saito T, Maruyama J, Fujiwara T, Maemura S, Ito M, Naito AT, Harada M, Toko H, Nomura S, Kumagai H, Ikeda Y, Ueno H, Takimoto E, Akazawa H, Morita H, Aburatani H, Hata Y, Uchiyama M, Komuro I, JACC: Basic to Translational Science, 3:639-653, 2018年11月
Pressure overload impairs cardiac function in long-chain fatty acid transporter CD36-knockout mice, (Nakatani K), Masuda D, Kobayashi T, Sairyo M, Zhu Y, Okada T, Naito AT, Ohama T, Koseki M, Oka T, Akazawa H, Nishida M, Komuro I, Sakata Y, Yamashita S, International Heart Journal, 60:159-167, 2019年01月
High-throughput single-molecule RNA imaging analysis reveals heterogenous responses of cardiomyocytes to hemodynamic overload, (Satoh M), Nomura S, Harada M, Yamaguchi T, Ko T, Sumida T, Toko H, Naito AT, Takeda N, Tobita T, Fujita T, Ito M, Fujita K, Ishizuka M, Kariya T, Akazawa H, Kobayashi Y, Morita H, Takimoto E, Aburatani H, Komuro I, Journal of Molecular and Cellular Cardiology, 128:77-89, 2019年03月
Overview of the 83rd Annual Scientific Meeting of the Japanese Circulation Society - Renaissance of Cardiology for the Creation of Future Medicine, (Akazawa H), Toko H, Harada M, Ueda K, Kodera S, Kiyosue A, Fujiu K, Hatano M, Daimon M, Ando J, Takimoto E, Morita H, Komuro I, Circulation Journal, 83:1829-1835, 2019年08月
OCT-Based Management of Nilotinib-Associated CAD in a Patient With Chronic Myeloid Leukemia, (Kiriyama H), Ishida J, Kadowaki H, Iwasa T, Kiyosue A, Kodera S, Ando J, Akazawa H, Komuro I, JACC: CardioOncology, 1:318-321, 2019年12月
Dawning of digital era in the management of hypertension, (Matsuoka R), Akazawa H, Kodera S, Komuro I, Hypertension Research, 43:1135-1140, 2020年11月
Cancer therapeutics-related cardiac dysfunction: insights from bench and bedside of onco-cardiology, (Kadowaki H), Akazawa H #, Ishida J, Komuro I, Circulation Journal, 84:1446-1453, 2020年08月
Transethnic Meta-analysis of Genome-wide Association Studies Identifies Three New Loci and Characterizes Population-specific Differences for Coronary Artery Disease, (Matsunaga H), Ito K, Akiyama M, Takahashi A, Koyama S, Nomura S, Ieki H, Ozaki K, Onouchi Y, Sakaue S, Suna S, Ogishima S, Yamamoto M, Hozawa A, Satoh M, Sasaki M, Yamaji T, Sawada N, Iwasaki M, Tsugane S, Tanaka K, Arisawa K, Ikezaki H, Takashima N, Naito M, Wakai K, Tanaka H, Sakata Y, Morita H, Sakata Y, Matsuda K, Murakami Y, Akazawa H, Kubo M, Kamatani Y, Komuro I, Circulation: Genomic and Precision Medicine, 13:e002670, 2020年06月
Diagnosing heart failure from chest X-ray images using deep learning, (Matsumoto T), Kodera S, Shinohara H, Ieki H, Yamaguchi T, Higashikuni Y, Kiyosue A, Ito K, Ando J, Takimoto E, Akazawa H, Morita H, Komuro I, International Heart Journal, 61:781-786, 2020年07月
A fetal case of myocarditis following myositis induced by pembrolizumab treatment for metastatic upper urinary tract urothelial carcinoma, (Matsui H), Kawai T, Sato Y, Ishida J, Kadowaki H, Akiyama Y, Yamada Y, Nakamura M, Yamada D, Akazawa H, Suzuki M, Komuro I, Kume H, International Heart Journal, 61:1070-1074, 2020年09月
Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease, (Koyama S), Ito K, Terao C, Koyama S, Ito K, Terao C, Akiyama M, Horikoshi M, Momozawa Y, Matsunaga H, Ieki H, Ozaki K, Onouchi Y, Takahashi A, Nomura S, Morita H, Akazawa H, Kim C, Seo JS, Higasa K, Iwasaki M, Yamaji T, Sawada N, Tsugane S, Koyama T, Ikezaki H, Takashima N, Tanaka K, Arisawa K, Kuriki K, Naito M, Wakai K, Suna S, Sakata Y, Sato H, Hori M, Sakata Y, Matsuda K, Murakami Y, Aburatani H, Kubo M, Matsuda F, Kamatani Y, Komuro I, Nature Genetics, 52:1169-1177, 2020年11月
Inhibition of transforming growth factor- signaling in myeloid cells ameliorates aortic aneurysmal formation in Marfan syndrome, (Hara H), Maemura S, Fujiwara T, Takeda N, Ishii S, Yagi H, Suzuki T, Harada M, Toko H, Kanaya T, Ijichi H, Moses HL, Takimoto E, Morita H, Akazawa H, Komuro I, PLoS One, 15:e0239908, 2020年11月
Cardio-Oncology in Japan: The Rapidly Rising Sun, (Oka T), Akazawa H, Sase K, Hatake K, Komuro I, JACC: CardioOncology, 2:815-818, 2020年12月
Factors associated with left ventricular reverse remodeling after percutaneous coronary intervention in patients with left ventricular systolic dysfunction, (Adachi Y), Kiyosue A, Ando J, Kawahara T, Kodera S, Minatsuki S, Kikuchi H, Inaba T, Kiriyama H, Hirose K, Shinohara H, Saito A, Fujiwara T, Hara H, Ueda K, Sakakura K, Hatana M, Harada M, Takimoto E, Akazawa H, Morita H, Momomura S, Fujita H, Komuro I, Scientific Reports, 11:239, 2021年01月
Mechanisms and management of immune checkpoint inhibitors-related cardiac adverse events, (Kadowaki H), Akazawa H, Ishida J, Komuro I, JMA Journal, 4:91-98, 2021年04月
Axitinib induces and aggravates hypertension irrespectively of prior treatment with tyrosine kinase inhibitors, (Kadowaki H), Ishida J, Akazawa H, Yagi H, Saga-Kamo A, Umei M, Matsuoka R, Liu Q, Matsunaga H, Maki H, Sato Y, Kume H, Komuro I, Circulation Reports, 3:234-240, 2021年03月
Automatic detection of vessel structure by deep learning using intravascular ultrasound images of the coronary arteries, (Shinohara H), Kodera S, Ninomiya K, Nakamoto M, Katsushika S, Saito A, Minatsuki S, Kikuchi H, Kiyosue A, Higashikuni Y, Takeda N, Fujiu K, Ando J, Akazawa H, Morita H, Komuro I, PLOS One, 16:e0255577, 2021年08月
Three-Dimensional Visualization of Hypoxia-Induced Pulmonary Vascular Remodeling in Mice, (Fujiwara T), Takeda N, Hara H, Ishii S, Numata G, Tokiwa H, Maemura S, Suzuki T, Takiguchi H, Kubota Y, Seo K, Sakata A, Nomura S, Hatano M, Ueda K, Harada M, Toko H, Takimoto E, Akazawa H, Nishimura S, Komuro I, Circulation, 144:1452-1455, 2021年10月
The Effectiveness of a Deep Learning Model to Detect Left Ventricular Systolic Dysfunction from Electrocardiograms, (Katsushika S), Kodera S, Nakamoto M, Ninomiya K, noue S, Sawano S, Kakuda N, Takiguchi H, Shinohara H, Matsuoka R, Ieki H, Higashikuni Y, Nakanishi K, Nakao T, Seki T, Takeda N, Fujiu K, Daimon M, Akazawa H, Morita H, Komuro I, International Heart Journal, 62:1332-1341, 2021年12月
Deep learning algorithm to detect cardiac sarcoidosis from an echocardiographic movie, (Katsushika S), Kodera S, Nakamoto M, Ninomiya K, Kakuda N, Shinohara H, Matsuoka R, Ieki H, Uehara M, Higashikuni Y, Nakanishi K, Nakao T, Takeda N, Fujiu K, Daimon M, Ando J, Akazawa H, Morita H, Komuro I, Circulation Journal, 86:87-95, 2021年12月
Detection of profound myocardial damage by cardiac MRI in a patient with severe cardiotoxicity induced by anti-HER2 therapy, (Kadowaki H), Ishida J, Uehara M, Ishizuka M, Kiyosue A, Hatano M, Shimada S, Ono M, Akazawa H, Komuro I, International Heart Journal, 62:1436-1441, 2021年12月
Oral Administration of Euglena gracilis Z Alleviates Constipation and Cardiac Dysfunction in a Mouse Model of Isoproterenol-induced Heart Failure, (Umei M), Akazawa H, Saga-Kamo A, Yagi H, Liu Q, Matsuoka R, Kadowaki H, Shindo A, Nakashima A, Yasuda K, Suzuki K, Komuro I, Circulation Reports, 4:83-91, 2021年12月
Deep learning model to detect significant aortic regurgitation using electrocardiography: Detection model for aortic regurgitation, (Sawano S), Kodera S, Katsushika S, Nakamoto M, Ninomiya K, Shinohara H, Higashikuni Y, Nakanishi K, Nakao T, Seki T, Takeda N, Fujiu K, Daimon M, Akazawa H, Morita H, Komuro I, Journal of Cardiology, 79:334-341, 2022年03月
Oxidized LDL but not angiotensin II induces cardiomyocyte hypertrophic responses through the interaction between LOX-1 and AT 1 receptors, (Lin L), Zhou N, Kang L, Wang Q, Wu J, Wang X, Yang C, Zhang G, Chen Y, Jiang H, Chen R, Yang X, Sun A, Gong H, Ren J, Akazawa H, Issei K, Ge J, Yang C, Zou Y, Journal of Molecular and Cellular Cardiology, 162:110-118, 2022年01月
Prospects for cardiovascular medicine using artificial intelligence, (Kodera S), Akazawa H, Morita H, Komuro I, Journal of Cardiology, 79:319-325, 2022年03月
Sick Sinus Syndrome: More Than a Needle-in-a-haystack Manifestation of Immune Checkpoint Inhibitor-associated Myocarditis, (Kadowaki H), Akazawa H, Internal Medicine, 61:2101-2102, 2022年07月
Nonsyndromic arteriopathy and aortopathy and vascular Ehlers-Danlos syndrome causing COL3A1 variants, (Yagi H), Takeda N, Amiya E, Akiyama N, Chang H, Ishiura H, Sato J, Akazawa H, Morita H, Komuro I, American Journal of Medical Genetics Part A, 188:2777-2782, 2022年09月
Antihypertensive Drugs and Cancer Risk, (Kidoguchi S), Sugano N, Yokoo T, Kaneko H, Akazawa H, Mukai M, Node K, Yano Y, Nishiyama A, American Journal of Hypertension, 35:767-783, 2022年09月
Automatic Detection of Left Ventricular Dilatation and Hypertrophy from Electrocardiograms Using Deep Learning, (Kokubo T), Kodera S, Sawano S, Katsushika S, Nakamoto M, Takeuchi H, Kimura N, Shinohara H, Matsuoka R, Nakanishi K, Nakao T, Higashikuni Y, Takeda N, Fujiu K, Daimon M, Akazawa H, Morita H, Matsuyama Y, Komuro I, International Heart Journal, 63:939-947, 2022年09月
Age prediction from coronary angiography using a deep neural network: Age as a potential label to extract prognosis-related imaging features, (Sawano S), Kodera S, Sato M, Katsushika S, Sukeda I, Takeuchi H, Shinohara H, Kobayashi A, Takiguchi H, Hirose K, Kamon T, Saito A, Kiriyama H, Miura M, Minatsuki S, Kikuchi H, Higashikuni Y, Takeda N, Fujiu K, Ando J, Akazawa H, Morita H, Komuro I, PLoS One, 17:e0276928, 2022年10月
Deep learning-based age estimation from chest X-rays indicates cardiovascular prognosis, (Ieki H), Ito K, Saji M, Kawakami R, Nagatomo Y, Takada K, Kariyasu T, Machida H, Koyama S, Yoshida H, Kurosawa R, Matsunaga H, Miyazawa K, Ozaki K, Onouchi Y, Katsushika S, Matsuoka R, Shinohara H, Yamaguchi T, Kodera S, Higashikuni Y, Fujiu K, Akazawa H, Iguchi N, Isobe M, Yoshikawa T, Komuro I, Communications Medicine, 2:159, 2022年12月
Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction, (Miyazawa K), Ito K, Ito M, Zou Z, Kubota M, Nomura S, Matsunaga H, Koyama S, Ieki H, Akiyama M, Koike Y, Kurosawa R, Yoshida H, Ozaki K, Onouchi Y, BioBank Japan P, Takahashi A, Matsuda K, Murakami Y, Aburatani H, Kubo M, Momozawa Y, Terao C, Oki S, Akazawa H, Kamatani Y, Komuro I, Nature Genetics, 55:187-197, 2023年02月
Novel AGL variants in a patient with glycogen storage disease type IIIb and pulmonary hypertension caused by pulmonary veno-occlusive disease: A case report, (Shindo A), Ueda K, Minatsuki S, Nakayama Y, Hatsuse S, Fujita K, Nomura S, Hatano M, Takeda N, Akazawa H, Komuro I, Frontiers in Genetics, 14:1148067, 2023年03月
Pericardial grafting of cardiac progenitor cells in self-assembling peptide scaffold improves cardiac function after myocardial infarction, (Kanda M), Nagai T, Kondo N, Matsuura K, Akazawa H, Komuro I, Kobayashi Y, Cell Transplantation, 32:9636897231174078, 2023年01月
An explainable artificial intelligence-enabled electrocardiogram analysis model for the classification of reduced left ventricular function, (Katsushika S), Kodera S, Sawano S, Shinohara H, Setoguchi N, Tanabe K, Higashikuni Y, Takeda N, Fujiu K, Daimon M, Akazawa H, Morita H, Komuro I, European Heart Journal Digital Health, 4:254-264, 2023年04月
Coronary Periarteritis and Pericardial Thickening Could Be Predictors for Coronary Artery Events Complicated by IgG4-Related Disease, (Yagi H), Amiya E, Uehara M, Minatsuki S, Hatano M, Takeda N, Akazawa H, Komuro I, CJC Open, 5:480-489, 2023年05月
PGC-1α-mediated angiogenesis prevents pulmonary hypertension in mice, (Fujiwara T), Takeda N, Hara H, Ishii S, Numata G, Tokiwa H, Katoh M, Maemura S, Suzuki T, Takiguchi H, Yanase T, Kubota Y, Nomura S, Hatano M, Ueda K, Harada M, Toko H, Takimoto E, Akazawa H, Morita H, Nishimura S, Komuro I, JCI Insight, 8:e162632, 2023年09月
Deep Learning Models for Predicting Left Heart Abnormalities From Single-Lead Electrocardiogram for the Development of Wearable Devices, (Sato M), Kodera S, Setoguchi N, Tanabe K, Kushida S, Kanda J, Saji M, Nanasato M, Maki H, Fujita H, Kato N, Watanabe H, Suzuki M, Takahashi M, Sawada N, Yamasaki M, Sawano S, Katsushika S, Shinohara H, Takeda N, Fujiu K, Daimon M, Akazawa H, Morita H, Komuro I, Circulation Journal, 88:146-156, 2023年12月
A case of progressive right ventricular failure with ventricular arrhythmia and aortic insufficiency after implantable left ventricular assist device implantation, (Jimba T), Hatano M, Fujiwara T, Akazawa H, Watanabe M, Kinugawa K, Ono K, Komuro I, Journal of Cardiology Cases, 29:7-10, 2023年09月
Asymptomatic and symptomatic cardiac toxicity associated with immune checkpoint inhibitors: insights from a Japanese registry, (Tamura Y), Tamura Y, Ohtsu H, Nakamori S, Maruyama K, Muraoka N, Shoji M, Tajiri K, Tomita H, Iso Y, Sugimura K, Yamada H, Kinugawa K, Morimoto R, Akazawa H, Harada K, Nakano S, Tsujita K, Gunji T, Tsuruda T, Nakamura A, Maruyama M, Miyake Y, Hatanaka K, Kawano H, Sato W, Yano S, Imanaka-Yoshida K, Komuro I, European Heart Journal Open, 6:oeag079, 2026年05月
Shared and reciprocal mechanisms between heart failure and cancer: an emerging concept of heart-cancer axis, (Kadowaki H), Akazawa H, Shindo A, Ueda T, Ishida J, Komuro I, Circulation Journal, 88:182-188, 2024年01月
The potential of the transformer-based survival analysis model, SurvTrace, for predicting recurrent cardiovascular events and stratifying high-risk patients with ischemic heart disease, (Shinohara H), Kodera S, Nagae Y, Hiruma T, Kobayashi A, Sato M, Sawano S, Kamon T, Narita K, Hirose K, Kiriyama H, Saito A, Miura M, Minatsuki S, Kikuchi H, Takeda N, Akazawa H, Morita H, Komuro I, PLoS One, 19:e0304423, 2024年06月
Applying masked autoencoder-based self-supervised learning for high-capability vision transformers of electrocardiographies, (Sawano S), Kodera S, Setoguchi N, Tanabe K, Kushida S, Kanda J, Saji M, Nanasato M, Maki H, Fujita H, Kato N, Watanabe H, Suzuki M, Takahashi M, Sawada N, Yamasaki M, Sato M, Katsushika S, Shinohara H, Takeda N, Fujiu K, Daimon M, Akazawa H, Morita H, Komuro I, PLoS One, 19:e0307978, 2024年08月
Association Between Clonal Hematopoiesis and Left Ventricular Reverse Remodeling in Nonischemic Dilated Cardiomyopathy, (Inoue S), Ko T, Shindo A, Nomura S, Yamada T, Jimba T, Dai Z, Nakao H, Suzuki A, Kashimura T, Iwahana T, Goto K, Matsushima S, Ishida J, Amiya E, Zhang B, Kubota M, Sawami K, Heryed T, Yamada S, Katoh M, Katagiri M, Ito M, Nayakama Y, Fujiu K, Hatano M, Takeda N, Takimoto E, Akazawa H, Morita H, Yamaguchi J, Inomata T, Kobayashi Y, Minamino T, Tsutsui H, Kurokawa M, Aiba A, Aburatani H, Komuro I, JACC: Basic to Translational Science, 9:956-967, 2024年06月
Association of Multiple Nonhypertrophic Cardiomyopathy-Related Genetic Variants and Outcomes in Patients With Hypertrophic Cardiomyopathy, (Hiruma T), Inoue S, Dai Z, Nomura S, Kubo T, Sugiura K, Suzuki A, Kashimura T, Matsushima S, Yamada T, Tobita T, Katoh M, Ko T, Ito M, Ishida J, Amiya E, Hatano M, Takeda N, Takimoto E, Akazawa H, Morita H, Yamaguchi J, Inomata T, Tsutsui H, Kitaoka H, Aburatani H, Takeda N, Komuro I, JACC: Heart Failure, 12:2041-2052, 2024年12月
Deep Learning to Detect Pulmonary Hypertension from the Chest X-Ray Images of Patients with Systemic Sclerosis, (Shimbo M), Hatano M, Katsushika S, Kodera S, Isotani Y, Sawano S, Matsuoka R, Minatsuki S, Inaba T, Maki H, Sumida H, Takeda N, Akazawa H, Komuro I, International Heart Journal, 65:1066-1074, 2024年11月
Deep Learning-Based Identification of Echocardiographic Abnormalities from Electrocardiograms, (Fujiki G), Kodera S, Setoguchi N, Tanabe K, Kushida S, Saji M, Nanasato M, Maki H, Fujita H, Kato N, Watanabe H, Suzuki M, Takahashi M, Sawada N, MD, Ando J, Sato M, Sawano S, Katsushika S, Shinohara H, Takeda N, Fujiu K, Akazawa H, Morita H, Komuro I, JACC: Asia, 5:88-98, 2024年12月
XOR-Derived ROS in Tie2-Lineage Cells Including Endothelial Cells Promotes Aortic Aneurysm Progression in Marfan Syndrome, (Hiroki Yagi), Hiroshi Akazawa, Qing Liu, Kimiko Yamamoto, Kan Nawata, Akiko Saga-Kamo, Masahiko Umei, Hiroshi Kadowaki, Ryo Matsuoka, Akito Shindo, Shun Okamura, Haruhiro Toko, Norifumi Takeda, Masahiko Ando, Haruo Yamauchi, Norihiko Takeda, Mehdi A Fini, Minoru Ono, Issei Komuro, Arteriosclerosis, Thrombosis, and Vascular Biology, 45:e63-e77, 2025年03月
An ensemble learning model for detection of pulmonary hypertension using electrocardiogram, chest X-ray, and brain natriuretic peptide, (Risa Kishikawa), Satoshi Kodera, Naoto Setoguchi, Kengo Tanabe, Shunichi Kushida, Mamoru Nanasato, Hisataka Maki, Hideo Fujita, Nahoko Kato, Hiroyuki Watanabe, Masao Takahashi, Naoko Sawada, Jiro Ando, Masataka Sato, Shinnosuke Sawano, Hiroki Shinohara, Koki Nakanishi, Shun Minatsuki, Junichi Ishida, Katsuhito Fujiu, Hiroshi Akazawa, Hiroyuki Morita, Norihiko Takeda, European Heart Journal Digital Health, 6:209-217, 2025年01月
Heart failure monitoring with a single‑lead electrocardiogram at home, (Eriko Hasumi), Katsuhito Fujiu, Ying Chen, Sumie Miyamoto, Mitsunori Oida, Yu Shimizu, Kunihiro Kani, Kohsaku Goto, Ryoko Uchida, Yuxiang Liu, Tsukasa Oshima, Jun Matsuda, Takumi J Matsubara, Junichi Sugita, Yukiteru Nakayama, Gaku Oguri, Toshiya Kojima, Yujin Maru, Satoshi Kodera, Hiroshi Akazawa, Morio Shoda, Issei Komuro, International Journal of Cardiology, 432:133203, 2025年08月
Prognostic Factors Associated With Early Recovery From Veno-Arterial Extracorporeal Membrane Oxygenation Support in Patients With Fulminant Myocarditis, (Tomomi Ueda), Eisuke Amiya, Masaru Hatano, Kosuke Inoue, Junichi Ishida, Shun Minatsuki, Hiroki Yagi, Chie Bujo, Yoshitaka Isotani, Nobutaka Kakuda, Takanobu Yamada, Norifumi Takeda, Hiroshi Akazawa, Koshiro Kanaoka, Kenji Onoue, Yoshihiko Saito, Shungo Hikoso, Issei Komuro, Norihiko Takeda, Journal of the American Heart Association, 14:e039673, 2025年06月
Perivascular inflammation in the progression of aortic aneurysms in Marfan syndrome, (Hiroyuki Sowa), Hiroki Yagi, Kazutaka Ueda, Masaki Hashimoto, Kohei Karasaki, Qing Liu, Atsumasa Kurozumi, Yusuke Adachi, Tomonobu Yanase, Shun Okamura, Bowen Zhai, Norifumi Takeda, Masahiko Ando, Haruo Yamauchi, Nobuhiko Ito, Minoru Ono, Hiroshi Akazawa, Issei Komuro, JCI Insight, 10:e184329, 2025年08月
Clinical characteristics and in-hospital mortality of chronic myeloid leukemia patients with ischemic heart disease: insights from the JROAD-DPC registry, (Akito Shindo), Hiroshi Akazawa, Tomomi Ueda, Hiroshi Kadowaki, Junichi Ishida, Issei Komuro, European Heart Journal Open, 5:oeaf101, 2025年08月
Enhancing Chest Radiography Artificial Intelligence Model with Electrocardiogram for Improved Detection of Low Ejection Fraction, (Masataka Sato), Satoshi Kodera, Shogo Hamano, Naoto Setoguchi, Kengo Tanabe, Shunichi Kushida, Mike Saji, Mamoru Nanasato, Hisataka Maki, Hideo Fujita, Nahoko Kato, Hiroyuki Watanabe, Masao Takahashi, Naoko Sawada, Jiro Ando, Shinnosuke Sawano, Risa Kishikawa, Hiroki Shinohara, Norifumi Takeda, Katsuhito Fujiu, Koki Nakanishi, Hiroshi Akazawa, Hiroyuki Morita, Norihiko Takeda, International Heart Journal, 66:771-779, 2025年05月
Pregnant Patient With Infrarenal Abdominal Aortic Aneurysm Successfully Treated With EVAR, (Tomomi Ueda), Hiroki Yagi, Nana Akiyama, Naoya Akiba, Katsuyuki Hoshina, Hiroshi Akazawa, Norifumi Takeda, Norihiko Takeda, JACC: Case Reports, 30:105287, 2025年10月
Genome-wide analysis of heart failure yields insights into disease heterogeneity and enables prognostic prediction in the Japanese population, (Nobuyuki Enzan), Kazuo Miyazawa, Satoshi Koyama, Ryo Kurosawa, Hirotaka Ieki, Hiroki Yoshida, Fumie Takechi, Masashi Fukuyama, Ryosuke Osako, Kohei Tomizuka, Xiaoxi Liu, Kouichi Ozaki, Yoshihiro Onouchi, the BioBank Japan Project, Koichi Matsuda, Yukihide Momozawa, Hiroyuki Aburatani, Yoichiro Kamatani, Takanori Yamaguchi, Hiroshi Akazawa, Koichi Node, Patrick T Ellinor, Michael G Levin, Scott M Damrauer, Benjamin F Voight, Jacob Joseph, Yan V Sun, Chikashi Terao, Toshiharu Ninomiya, Issei Komuro, Kaoru Ito, Nature Communications, 16:9680, 2025年11月
Inverse Agonist Activity of Angiotensin II Receptor Blocker Is Crucial for Prevention of Progressive Aortic Dilatation in Marfan Syndrome, (Hiroki Yagi), Hiroshi Akazawa, Qing Liu, Sayo M. Ito, Masahiko Umei, Hiroshi Kadowaki, Ryo Matsuoka, Akito Shindo, Shun Okamura, Tomomi Ueda, Akiko Saga-Kamo, Kazutaka Ueda, Norifumi Takeda, Tappei Takada, Issei Komuro, Arteriosclerosis, Thrombosis, and Vascular Biology, 46:132-144, 2026年01月
Risk Factors and Prognostic Significance of Non-Perioperative Atrial Fibrillation in Lung Cancer Patients, (Tsukasa Oshima), Hiroshi Akazawa, Junichi Ishida, Hiroshi Kadowaki, Akito Shindo, Tomomi Ueda, Yosuke Amano, Kousuke Watanabe, Katsuhito Fujiu, Hidenori Kage, Issei Komuro, Circulation Reports, 7:1171-1180, 2025年10月
Feasibility study protocol for the evaluation of home blood pressure in patients receiving angiogenesis inhibitor therapy: a multicenter observational study, (Kaori Kitaoka), Satoshi Morimoto, Shintaro Minegishi, Hiroshi Kato, Yasuyuki Kitahara, Wataru Shioyama, Taro Shiga, Kazuko Tajiri, Masaaki Shoji, Mitsuhiro Fukata, Hiroshi Akazawa, Mikio Mukai, Yuichiro Yano, Koichi Node, Akira Nishiyama, Hypertension Research, Hypertension Research:1441-1447, 2026年04月
