SAKAI Daisuke
| ■Faculty | Natural Sciences | |||
| ■Position | Associate Professor | |||
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Research
Overview of research:
I analyze the role of physiological hypoxia on cerebral development in mice using techniques of molecular developmental biology.
Research Activities
Published Papers
- Neuron-specific loss of Ppp6c induces neonatal death and decreases the number of cortical neurons and interneurons, (Miki Matsuoka), Daisuke Sakai, Hiroshi Shima, Toshio Watanabe, 693:149353-149353, Jan. 2024
- Glycolytic activity is required for the onset of neural plate folding during neural tube closure in mouse embryos, Daisuke Sakai, Yuki Murakami, Daichi Shigeta, Mitsuhiro Tomosugi, Hiromi Sakata-Haga, Toshihisa Hatta, Hiroki Shoji, Frontiers in Cell and Developmental Biology, 11:1212375, Jul. 2023
- Maternal Inflammation with Elevated Kynurenine Metabolites Is Related to the Risk of Abnormal Brain Development and Behavioral Changes in Autism Spectrum Disorder, Yuki Murakami, Yukio Imamura, Yoshiyuki Kasahara, Chihiro Yoshida, Yuta Momono, Ke Fang, Daisuke Sakai, Yukuo Konishi, Toshimasa Nishiyama, Cells, 12:1087, Apr. 2023
- Exposure to Maternal Immune Activation Causes Congenital Unfolded Protein Response Defects and Increases the Susceptibility to Postnatal Inflammatory Stimulation in Offspring, Yo Shimizu, Tsuyoshi Tsukada, Hiromi Sakata-Haga, Daisuke Sakai, Hiroki Shoji, Yutaka Saikawa, Toshihisa Hatta, Journal of Inflammation Research, 14:355-365, Feb. 2021
- Altered kynurenine pathway metabolites in a mouse model of human attention-deficit hyperactivity/autism spectrum disorders: A potential new biological diagnostic marker, Murakami Yuki, Imamura Yukio, Saito Kuniaki, Sakai Daisuke, Motyama Jun, Scientific reports, 9:13182, Sep. 2019