Lens–specific conditional knockout of tropomyosin 1 gene in mice causes abnormal fiber differentiation and lens opacity., Teppei Shibata, Masahito Ikawa, Ryo Sakasai, Yasuhito Ishigaki, Etsuko Kiyokawa, Kuniyoshi Iwabuchi, Dhirendra P. Singh, Hiroshi Sasaki, Eri Kubo, Mechanisms of Ageing and Development, 196:111492, 2021年04月
USP42 enhances homologous recombination repair by promoting R-loop resolution with a DNA-RNA helicase DHX9, (Matsui Misaki), Sakasai Ryo, Abe Masako, Kimura Yusuke, Kajita Shoki, Torii Wakana, Katsuki Yoko, Ishiai Masamichi, Iwabuchi Kuniyoshi, Takata Minoru, Nishi Ryotaro, Oncogenesis, 9:60, 2020年06月
Replication stress induces accumulation of FANCD2 at central region of large fragile genes, (Y.Okamoto),WM.Iwasaki, K.Kugou, KK.Takahashi, A.Oda, K.Sato, W.Kobayashi, H.Kawai, R.Sakasai, A.Takaori-Kondo, T.Yamamoto, MT.Kanemaki, M.Taoka, T.Isobe, K.Kurumizaka, H.Innan, K.Ohta, M.Ishiai, M.Takata, Nucleic acids research, 46:2932, 2018年04月
Caspase-mediated cleavage of X-ray repair cross-complementing group 4 promotes apoptosis by enhancing nuclear translocation of caspase-activated DNase., Yumi.Sunatani, Radhika Pankaj Kamdar, Mukesh Kumar Sharma, Tadashi.Matsui, Ryo.Sakasai, Mitsumasa.Hashimoto, Yasuhito.Ishigaki, Yoshihisa.Matsumoto, Kuniyoshi.Iwabuchi, Experimental cell research, 362:450, 2018年01月
PARP inhibition disrupts repair of one-ended DNA double-strand breaks, Sakasai, Ryo;Iwabuchi, Kuniyoshi, CANCER SCIENCE, 109:577-577, 2018年01月
Aquarius is required for proper CtIP expression and homologous recombination repair., Sakasai Ryo;Isono Mayu;Wakasugi Mitsuo;Hashimoto Mitsumasa;Sunatani Yumi;Matsui Tadashi;Shibata Atsushi;Matsunaga Tsukasa;Iwabuchi Kuniyoshi, Scientific reports, 7:13808, 2017年
Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability., (M.Iimori), S.Watanabe, S.Kiyonari, K.Matsuoka, R.Sakasai, H.Saeki, E.Oki, H.Kitao, Y.Maehara, Nature Communications, 7:11117-11117, 2016年
The distinctive cellular responses to DNA strand breaks caused by a DNA topoisomerase I poison in conjunction with DNA replication and RNA transcription., R.Sakasai, K.Iwabuchi, Genes & genetic systems, 90:187-194, 2015年
Arf/p53 module, which induces apoptosis, downregulates histone H2AX to allow normal cells to survive in the presence of anti-cancer drugs, (Atsumi Y), Inase A, Osawa T, Sugihara E, Sakasai R, Fujimori H, Teraoka H, Saya H, Kanno M, Nakagama H, Masutani M, Yoshioka KI, The Journal of biological chemistry., 288:13269-13277, 2013年
PARP and CSB modulate the processing of transcription-mediated DNA strand breaks, Sakai A, Sakasai R, Kakeji Y, Kitao H, Maehara Y, Genes & genetic systems., 87:265-272, 2012年
CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication, Sakasai R, Sakai A, Iimori M, Kiyonari S, Matsuoka K, Kakeji Y, *Kitao H, Maehara Y, Kakeji Y, Kitao H, Maehara Y, Genes to cells : devoted to molecular & cellular mechanisms, 17:962-970, 2012年
ATR-Chk1 signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity, (Fujinaka Y), Matsuoka K, Iimori M, Tuul M, Sakasai R, Yoshinaga K, Saeki H, Morita M, Kakeji Y, Gillespie DA, Yamamoto K, Takata M, Kitao H, Maehara Y, DNA repair., 11:247-158, 2012年
Transcription-dependent activation of ataxia telangiectasia-mutated prevents DNA-dependent protein kinase-mediated cell death in response to topoisomerase I poison, Sakasai R, Teraoka H, Tibbetts RS, The Journal of biological chemistry., 285:15201-15208, 2010年
Proteasome inhibition suppresses DNA-dependent protein kinase activation caused by camptothecin, Sakasai R, Teraoka H, Tibbetts RS, DNA repair., 9:76-82, 2010年
DPPA4 modulates chromatin structure via association with core histone H3 and DNA in mouse embryonic stem cells, (Masaki H), Nishida T, Sakasai R, Teraoka H, Genes to cells : devoted to molecular & cellular mechanisms, 15:327-337, 2010年
Potentiation of ALS-associated TDP-43 aggregation by the proteasome-targeting factor, Ubiquilin 1, (Kim SH), Shi Y, Hanson KA, Williams LM, Sakasai R, Bowler MJ, Tibbetts RS, The Journal of biological chemistry., 284:8083-8092, 2009年
RNF8-dependent and independent activation of 53BP1 in response to DNA damage, Sakasai R, Tibbetts RS, The Journal of biological chemistry., 283:13549-13555, 2008年
Differential involvement of phosphatidylinositol 3-kinase- related kinases in replication protein A2 hyperphosphorylation in response to replication-mediated DNA double-strand breaks, Sakasai R, Shinohe K, Ichijima Y, Okita N, Shibata A, Asahina K, Teraoka H, Genes to cells : devoted to molecular & cellular mechanisms, 11:237-246, 2006年
