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下平 滋隆 シモダイラ シゲタカ

所属部署名再生医療学, 再生医療センター, 先端医療研究領域
職名教授
 
 

研究者基本情報

学位

  • 博士(医学)

研究活動情報

論文

  • WT1 Peptide Vaccine is Unaffected by Airport Screening X-Irradiation(Y.Higuchi), M.Kawakubo, M.Yuzawa, K.Sano, S.ShimodairaAustin Journal of Vaccines & Immunotherapeutics3:1010-10102016年09月
  • Interferon-α-inducible Dendritic Cells Matured with OK-432 Exhibit TRAIL and Fas Ligand Pathwaymediated Killer Activity(T.Koya), R.Yanagisawa, Y.Higuchi, K.Sano, S.ShimodairaScientific Reports3:1-42017年02月
  • Interferon-α-inducible Dendritic Cells Matured with OK-432 Exhibit TRAIL and Fas LIgand Pathway-mediated Killer ActivityTerutsugu Koya,Ryu Yanagisawa,Yumiko Higuchi,Kenji Sano&Shigetaka ShimodairaSCIENTIFIC REPORTS7:421452017年02月
  • Significance of Wilms tumor 1 antigen as a canser vaccine for pancreatic cancerKoido.S, Okamoto.M ,Kobayashi.M, Shimodaira.S, Sugiyama.HDiscovery Medicine130:41-492017年08月
  • Clinical effect and immunological response in patients with advanced malignant glioma treated with WT1-pulsed dendritic cell-based immunotherapy: A report of two cases.Sakai K, Shimodaira S, Maejima S, Sano K, Higuchi Y, Koya T, Sugiyama H, Hongo K.Interdisciplinary Neurosurgery9:24-292017年
  • Administration of platelet concentrates suspended in bicarbonated Ringer's solution in children who had platelet transfusion reactions(Kobayashi J), Yanagisawa R, Ono T, Tatsuzawa Y, Tokutake Y, Kubota N, Hidaka E, Sakashita K, Kojima S, Shimodaira S, Nakamura TVOX SANGUINIS113:128-1352018年02月
  • Comparison of administration of platelet concentrates suspended in M-sol or BRS-A for pediatric patients(Shunsuke Kojima), Ryu Yanagisawa, Miyuki Tanaka, Yozo Nakazawa, Shigetaka ShimodairaTRANSFUSION58:2952-29582018年12月
  • Evaluation of Gelatin-Hybridized Chelate-Setting Calcium Phosphate Cements in Alveolar Bone Defects of Canine MandibleGoichi Matsumoto, Yoshihiko Sugita, Katsutoshi Kubo, Waka Yoshida, Hatsuhiko Maeda, Mamoru Aizawa, Shigetaka Shimodaira, Yukihiko KinoshitaBiomedical Journal of Scientific & Technical Research3:3420-34262018年04月
  • Feasibility and Immune Response of WT1 Peptide Vaccination in Combination with OK-432 for Paediatric Solid Tumors(Hirabayashi K), Yanagisawa R, Saito S, Higuchi Y, Koya T, Sano K, Koido S, Okamoto M, Sugiyama H, Nakazawa Y, Shimodaira SANTICANCER RESEARCH38:2227-22342018年04月
  • Prognostic significance of Wilms' tumor 1 expression in patients with pancreatic ductal adenocarcinoma(Tomoya Kanai), Zensho Ito, Yusuke Oji, Machi Suka, Sumiyuki Nishida, Kazuki Takakura, Mikio Kajihara, Masayuki Saruta, Shuichi Fujioka, Takeyuki Misawa, Tadashi Akiba, Hiroyuki Yanagisawa, Shigetaka Shimodaira, Masato Okamoto, Haruo Sugiyama, Shigeo KoidoOncology Letters16:2682-26922018年08月
  • WT1-pulsed Dendritic Cell Vaccine Combined with Chemotherapy for Resected Pancreatic Cancer in a Phase I Study(Yanagisawa R), Koizumi T, Koya T, Sano K, Koido S, Nagai K, Kobayashi M, Okamoto M, Sugiyama H, Shimodaira SANTICANCER RESEARCH38:2217-22252018年04月
  • Dendritic Cells Pre-Pulsed With Wilms' Tumor 1 in Optimized Culture for Cancer VaccinationTerutsugu Koya, Ippei Date, Haruhiko Kawaguchi, Asuka Watanabe, Takuya Sakamoto, Misa Togi, Tomohisa Kato Jr, Kenichi Yoshida, Shunsuke Kojima, Ryu Yanagisawa, Shigeo Koido, Haruo Sugiyama , Shigetaka ShimodairaPharmaceutics12: 2020年03月
  • Complete measurable residual disease response after combination chemotherapy with AML-type and ALL-type regimens in pediatric B/myeloid acute bilineal leukemia(Shoji Saito), Chiaki Taira, Kazuyuki Matsuda, Ryu Yanagisawa, Daisuke Morita, Tomonari Shigemura, Kentaro Yoshikawa, Miyuki Tanaka, Kazuo Sakashita, Saki Mukai, Shigetaka Shimodaira, Kenichi Koike, Yozo NakazawaLeukemia & Lymphoma61:967-9702020年04月
  • Investigation of factors associated with allergic transfusion reaction due to platelet transfusion and the efficacy of platelets resuspended in BRS‐A in adult patientsManjiro Yamanaka, Ryu Tanagisawa, Shunsuke Kojima, Hideyuki Nakazawa, Shigetaka ShimodairaTransfusion59:3405-34122019年12月
  • Predicted Markers of Overall Survival in Pancreatic Cancer Patients Receiving Dendritic Cell Vaccinations Targeting WT1Ito Z, Kan S1, Bito T, Horiuchi S, Akasu T, Yoshida S, Kajihara M1, Hokari A, Saruta M, Yoshida N, Kobayashi M, Ohkusa T, Shimodaira S, Okamoto M5 Sugiyama H, Koido SOncology97:135-1482019年09月
  • In Vivo Administration of Recombinant Human Granulocyte Colony-Stimulating Factor Increases the Immune Effectiveness of Dendritic Cell-Based Cancer VaccinationShimodaira S, Yanagisawa R, Koya T, Hirabayashi K, Higuchi Y, Sakamoto T, Togi M, Kato T Jr, Kobayashi T, Koizumi T, Koido S, Sugiyama HVaccines (Basel)7:1202019年09月

書籍等出版物

  • 第11章 第6節 癌に対するWT1ペプチドパルス樹状細胞ワクチンの開発
    ペプチド医薬品のスクリーニング・安定化・製剤化技術
    (岡本正人), 小井戸薫雄, 下平滋隆, 杉山治夫
    技術情報協会 2017年12月

競争的資金

  • 研究開発課題5:機能性細胞を用いた生体適合性担体の探索および製造システムに関する研究
    科学技術新興機構(JST):研究成果展開事業 産学共創プラットフォーム共同研究推進プログラム(OPERA)
    研究期間:2017年 - 2021年  
    代表者:下平滋隆


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