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小倉 慶雄 オグラ ヨシオ

所属部署名糖尿病・内分泌内科学
職名助教
 
 

研究活動情報

論文

  • Supplementation with Red Wine Extract Increases Insulin Sensitivity and Peripheral Blood Mononuclear Sirt1 Expression in Nondiabetic HumansMunehiro Kitada, Yoshio Ogura, Itaru Monno, Daisuke KoyaNutrients12:31082020年10月
  • Efficacy of SGLT2 inhibitor in type 2 diabetic patients under dietary instructions: A pilot studyMunehiro Kitada, Yoshio Ogura, Kayo Yamamoto, Kazunori Konishi, Akihiko Nakagawa, Atsushi Nakagawa, Dasiuke KoyaClinical and Medical Investigations5:1-82020年09月
  • Case report of superior mesenteric artery syndrome that developed in a lean type 2 diabetes patient and was associated with rapid body weight loss after sodium-glucose cotransporter 2 inhibitor administrationTaro Hirai, Munehiro Kitada, Yoshihiro Hayashi, Itaru Monno, Yuta Takagaki, Keiji Shimada, Yoshio Ogura, Mizue Fujii, Kazunori Konishi, Atsushi Nakagawa, Daisuke KoyaJournal of Diabetes Investigation11:1359-13622020年09月
  • Mechanism of Activation of Mechanistic Target of Rapamycin Complex 1 by MethionineMunehiro Kitada, Jing Xu, Yoshio Ogura, Itaru Monno, Daisuke KoyaFrontiers in Cell and Developmental Biology8:7152020年08月
  • Manganese Superoxide Dismutase Dysfunction and the Pathogenesis of Kidney DiseaseMunehiro Kitada, Jing Xu, Yoshio Ogura, Itaru Monno, Daisuke KoyaFrontiers in Physiology11:7552020年07月
  • CD38 inhibition by apigenin ameliorates mitochondrial oxidative stress through restoration of the intracellular NAD(+)/NADH ratio and Sirt3 activity in renal tubular cells in diabetic ratsYoshio Ogura, Munehiro Kitada, Jing Xu, Itaru Monno, Daisuke KoyaAGING-US12:11325-113362020年06月
  • Methionine abrogates the renoprotective effect of a low-protein diet against diabetic kidney disease in obese rats with type 2 diabetesMunehiro Kitada, Yoshio Ogura, Itaru Monno, Jing Xu, Daisuke KoyaAGING-US12:4489-45052020年03月
  • The impact of dietary protein intake on longevity and metabolic healthKitada Munehiro, Ogura Yoshio, Monno Itaru, Koya DaisukeEBioMedicine43:632-6402019年05月
  • Effect of switching to teneligliptin from other dipeptidyl peptidase-4 inhibitors on glucose control and renoprotection in type 2 diabetes patients with diabetic kidney diseaseKitada Munehiro, Ogura Yoshio, Nitta Kyoko, Fujii Mizue, Kanasaki Keizo, Konishi Kazunori, Iida Yasuo, Nakagawa Atsushi, Koya DaisukeJournal of diabetes investigation10:706-7132019年05月
  • Sirtuins and Type 2 Diabetes: Role in Inflammation, Oxidative Stress, and Mitochondrial FunctionKitada Munehiro, Ogura Yoshio, Monno Itaru, Koya DaisukeFrontiers in Endocrinology10:1872019年03月
  • Renal mitochondrial oxidative stress is enhanced by the reduction of Sirt3 activity, in Zucker diabetic fatty ratsYoshio.Ogura, Munehiro.Kitada, Itaru.Monno, Keizo,Kanasaki, Ai.Watanabe, Daisuke.KoyaRedox Report23:153-1592018年12月
  • A Low-Protein Diet for Diabetic Kidney Disease: Its Effect and Molecular Mechanism, an Approach from Animal StudiesMunehiro.Kitada, Yoshio.Ogura, Itaru.Monno, Daisuke.KoyaNutrients10:10(5). pii: E544. doi: 10.3390/nu10050544.2018年04月
  • Severe electrolytes disorders with the interstitial kidney alterations in the patient with the history of total thyroidectomy and parathyroidectomy: possible role of vitamin D deficiencyEmi.Kawakita, Keizo.Kanasaki, Taro.Hirai, Shin-ichi.Tsuda, Ai.Watanabe, Kyoko.Nitta, Munehiro.Kitada, Yoshio.Ogura, Yuta.Takagaki, Mizue.Fujii, Takako.Nagai, Keiji.Shimada, Susumu.Takagi, Yuiko.Mizunuma, Itaru.Monno, Shino.Fujimoto, Hiroshi.Minato, Nobuhiko.Miyatake, Atsushi.Nakagawa, Daisuke.KoyaClinical Case Reports6:983-9892018年04月
  • A low-protein diet exerts a beneficial effect on diabetic status and prevents diabetic nephropathy in Wistar fatty rats, an animal model of type 2 diabetes and obesityMunehiro.Kitada, Yoshio.Ogura, Taeko.Suzuki, Itaru.Monno, Keizo.Kanasaki, Ai.Watanabe, Daisuke.KoyaNutrition & Metabolism15:15:20.doi: 10.1186/s12986-018-0255-1. eCollection 2108.2018年03月
  • Exercise ameliorates diabetic kidney disease in type 2 diabetic fatty ratsItaru Monno, Yoshio Ogura, Jing Xu, Daisuke Koya, Munehiro KitadaAntioxidants (Basel, Switzerland)10:17542021年11月
  • Sirtuins and renal oxidative stressYoshio Ogura, Munehiro Kitada, Daisuk KoyaAntioxidants (Basel, Switzerland)10:11982021年07月
  • Dapagliflozin restores impaired autophagy and suppresses inflammation in high glucose-treated HK-2 cellsJing Xu, Munehiro Kitada, Yoshio Ogura, Haijie Liu, Daisuke KoyaCells10:14572021年06月
  • Sodium-glucose cotransporter 2 inhibitors in type 2 diabetes patients with renal function impairment slow the annual renal function decline, in a real clinical practiceTaro Hirai, Munehiro Kitada, Itaru Monno, Erina Oda, Yoshihiro Hayashi, Keiji Shimada, Yuta Takagaki, Yoshio Ogura, Mizue Fujii, Kazunori Konishi, Masaru Sakurai, Atsushi Nakagawa, Daisuke KoyaJournal of Diabetes Investigation12:1577-15852021年09月
  • Relationship between autophagy and metabolic syndrome Characteristics in the pathogenesis of atherosclerosisJing Xu, Munehiro Kitada, Yoshio Ogura, Daisuke KoyaFrontiers in Cell and Developmental Biology9:6418522021年04月
  • Effect of methionine restriction on aging: its relationship to oxidative stressMunehiro Kitada, Yoshio Ogura, Itaru Monno, Jing Xu, Daisuke KoyaBiomedicines9:1302021年01月
  • Adenosine/adenosine type 1 receptor signaling pathway did not play dominant roles on the influence of sodium-glucose cotransporter 2 inhibitor in the kidney of bovine serum albumin-overloaded streptozotocin-induced diabetic miceKeiji Shimada, Keizo Kanasaki, Makoto Kato, Yoshio Ogura, Yuta Takagaki, Itaru Monno, Taro Hirai , Munehiro Kitada, Daisuke KoyaJournal of Diabetes Investigation13:955-9642022年06月

書籍等出版物

  • Part5 エビデンスからSGLT2阻害薬の位置づけを検証する 2.腎機能のエビデンスからSGLT2阻害薬の位置づけを検証する
    SGLT2阻害薬のすべて 第2版(稲垣暢也編集)
    小倉慶雄,北田宗弘,古家大祐
    先端医学社 2018年05月
  • 4章 慢性合併症の病態とその治療 3.糖尿病腎症 4)糖尿病腎症に対する食事療法
    糖尿病治療のニューパラダイム 第4巻 糖尿病に合併する病態とその治療(加来浩平, 宇都宮一典, 綿田裕孝, 松田昌文, 池上博司編集)
    小倉慶雄, 北田宗弘, 古家大祐
    医薬ジャーナル社 2019年03月

受賞

  • 2019年06月 第9回日本抗加齢医学会総会 2019年度日本抗加齢医学会研究奨励賞 糖尿病性腎臓病に対する新規治療標的としてのNAD分解酵素CD38の抑制とSirt3の活性化の意義の解明~尿細管細胞ミトコンドリア酸化ストレスの軽減とアンチエイジングの観点から~
    小倉慶雄
  • 2019年 金沢医科大学医学会 金沢医科大学医学会「論文表彰」 Renal mitochondrial oxidative stress is enhanced by the reduction of Sirt3 activity, in Zucker diabetic fatty rats
    小倉 慶雄

競争的資金

  • 糖尿病におけるCD38の腎尿細管間質障害及び心筋障害の病態に果たす役割の解明
    その他:一般社団法人日本糖尿病学会 第7回日本糖尿病学会若手研究助成金
    研究期間:2021年 - 2021年  
    代表者:小倉 慶雄
  • CD38の糖尿病腎における尿細管間質障害及び心筋障害の病態に果たす役割の解明
    文部科学省:科学研究費 若手研究
    研究期間:2021年 - 2023年  
    代表者:小倉 慶雄