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九田 裕一 クダ ユウイチ

所属部署名生理学Ⅱ
職名講師
 
 

研究者基本情報

研究

    研究の概要:
    循環生理学,

専門分野

  • 生理学一般

学歴

  • 帝京科学大学

学位

  • 博士(医学)

研究活動情報

論文

  • Theoretical prediction of early afterdepolarization-evoked triggered activity formation initiating ventricular reentrant arrhythmiasKunichika Tsumoto, Takao Shimamoto, Yuma Aoji, Yukiko Himeno, Yuhichi Kuda, Mamoru Tanida, Akira Amano, Yasutaka KurataComputer Methods and Programs in Biomedicine240:1077222023年10月
  • Mechanisms for hypothermia during anaphylactic hypotension in awake ratsToshishige Shibamoto, Munenori Ono, Mamoru Tanida, Yuhichi Kuda, Yasutaka Kurata American journal of physiology. Regulatory, integrative and comparative physiology325:R446-R4552023年11月
  • Multiple Dynamical Mechanisms of Phase-2 Early Afterdepolarizations in a Human Ventricular Myocyte Model: Involvement of Spontaneous SR Ca2+ ReleaseYasutaka Kurata, Kunichika Tsumoto, Kenshi Hayashi, Ichiro Hisatome, Yuhichi Kuda, Mamoru TanidaFrontiers in Physiology10:15452020年01月
  • Angiopoietin-2 is released during anaphylactic hypotension in anesthetized and unanesthetized ratsTao Zhang, Toshishige Shibamoto, Mamoru Tanida, Makoto Taniguchi,Yuhichi Kuda, Wei Yang, Yasutaka KurataPLOS ONE15:e02420262020年11月
  • Tonic contraction develops in the colon during anaphylactic hypotension in anesthetized ratsTao Zhang, Toshishige Shibamoto, Mamoru Tanida, Yuhichi Kuda, Wei Yang, Yasutaka KurataJournal of Physiological Sciences69:953-9602019年
  • Anaphylaxis stimulates afferent vagal nerve activity and efferent sympathetic nerve activity in the stomach of anesthetized ratsKuda Y, Tanida M, Chen F, Kurata Y, Shibamoto TAMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSI317:R337-R3452019年08月
  • Renal response to anaphylaxis in anesthetized rats and isolated perfused rat kidneys: roles of nitric oxide.Mukai K, Kuda Y, Shibamoto T, Tanida M, Kurata Y, Yokoyama H.The Journal of Physiological Sciences68:689-6972018年09月
  • Restoration of mutant hERG stability by inhibition of HDAC6.Li P, Kurata Y, Endang M, Ninomiya H, Higaki K, Taufiq F, Morikawa K, Shirayoshi Y, Horie M, Hisatome I.J Mol Cell Cardiol.115:158-1692018年02月
  • Protective effects of topiroxostat on an ischemia-reperfusion model of rat hearts.Tanno S, Yamamoto K, Kurata Y, Adachi M, Inoue Y, Otani N, Mishima M, Yamamoto Y, Kuwabara M, Ogino K, Miake J, Ninomiya H, Shirayoshi Y, Okada F, Yamamoto K, Hisatome I.CIRCULATION JOURNAL82:1101-11112018年03月
  • Pretreatment with an angiotensin II receptor blocker abolished ameliorating actions of adipose-derived stem cell sheets on cardiac dysfunction and remodeling after myocardial infarction.Yamamoto K, Kurata Y, Inoue Y, Adachi M, Tsuneto M, Miake J, Ogino K, Ninomiya H, Yoshida A, Shirayoshi Y, Suyama Y, Yagi S, Nishimura M, Yamamoto K, Hisatome I.Regenerative Therapy9:79-882018年09月
  • Gastric vascular and motor responses to anaphylactic hypotension in anesthetized rats, in comparison to those with hemorrhagic or vasodilator-induced hypotensionKuda Y, Shibamoto T, Zhang T, Yang W, Tanida M, Kurata YJournal of Physiological Sciences68:253-2602018年05月
  • Anaphylactic hypotension causes renal and adrenal sympathoexcitaion and induces c-fos in the hypothalamus and medulla oblongataTanida M, Zhang T, Sun L, Song J, Yang W, Kuda Y, Kurata Y, Shibamoto T.EXPERIMENTAL PHYSIOLOGY103:790-8062018年06月
  • β2-adrenoceptor blockade deteriorates systemic anaphylaxis by enhancing hyperpermeability in anesthetized miceYang W, Shibamoto T, Kuda Y, Zhang T, Tanida M, Kurata Y.Allergy Asthma & Immunology Research10:52-612018年01月
  • Biphasic Renal Sympathetic Response to Hemorrhagic Hypotension in Mice.Zhang T, Tanida M, Uchida K, Suzuki Y, Yang W, Kuda Y, Kurata Y, Tominaga M, Shibamoto T.Shock48:576-5822017年
  • Mouse Anaphylactic Hypotension Is Characterized by Initial Baroreflex Independent Renal Sympathoinhibition Followed by Sustained Renal Sympathoexcitation.Zhang T, Tanida M, Uchida K, Suzuki Y, Yang W, Kuda Y, Kurata Y, Tominaga M, Shibamoto T.frontiers in Physiology8:6692017年
  • Dynamical mechanisms of phase-2 early afterdepolarizations in human ventricular myocytes: insights from bifurcation analyses of two mathematical models.Kurata Y, Tsumoto K, Hayashi K, Hisatome I, Tanida M, Kuda Y, Shibamoto T.Am J Physiol Heart Circ Physiol312:H106-H1272017年
  • Blockade of β2-adrenoceptor, rather than β1-adrenoceptor, deteriorates cardiac anaphylaxis in isolated blood-perfused rat hearts.Kuda Y, Shibamoto T, Yang W, Zhang T, Tanida M, Kurata Y.Cardiol J24:403-4082017年
  • Systemic vasoconstriction modulates the responses of pulmonary vasculature and airway to vasoconstrictors in anesthetized rats. M.Wang, T.Shibamoto, Y.Kuda, M.Tanida, Y.KurataExperimental Lung Research41:324-3342015年
  • Pulmonary vascular and airway responses to systemic vasoconstrictors in anesthetized BALB/c mice. M.Wang, T.Shibamoto, S.Shinomiya, Y.Yamamoto, Y.Kurata, Y.Kuda, M.Tanida, H.TogaJournal of cardiovascular pharmacology65:325-3342015年
  • Hypothalamic nesfatin-1 stimulates sympathetic nerve activity via hypothalamic ERK signaling.M.Tanida, H.Gotoh, N.Yamamoto, M.Wang, Y.Kuda, Y.Kurata, M.Mori, T.ShibamotoDiabetes64:3725-37362015年
  • Exercise attenuates ischemia-reperfusion injury of nonalcoholic fatty liver of OLETF rat. T.Shibamoto, Y.Kuda, M.Tanida, M.Wang, Y.KurataJournal of Gastroenterology, Pancreatology & Liver Disorders2:1-62015年
  • Mouse anaphylactic shock is caused by reduced cardiac output, but not by systemic vasodilatation or pulmonary vasoconstriction, via PAF and histamine.M.Wang, T.Shibamoto, M.Tanida, Y.Kuda, Y.KurataLife sciences.116:98-1052014年
  • Major contribution of vasospasm-induced coronary blood flow reduction to anaphylactic ventricular dysfunction assessed in isolated blood-perfused rat heartY.Kuda, Y.Kurata, M.Wang, M.Tanida, T.ShibamotoCardiology journal.21:11-172014年
  • Effects of anesthetics on the renal sympathetic response to anaphylactic hypotension in rats.L.Sun, M.Tanida, M.Wang, Y.Kuda, Y.Kurata, T.ShibamotoPloS one9:e113945:1-152014年
  • Angiotensin II and vasopressin are involved in the defense system against anaphylactic hypotension in anesthetized rats.M.Wang, T.Shibamoto, Y.Kuda, L.Sun, M.Tanida, Y.Kurata.European journal of pharmacology.731:38-432014年
  • Pulmonary vasoconstrictive and bronchoconstrictive responses to anaphylaxis are weakened via β2-adrenoceptor activation by endogenous epinephrine in anesthetized ratsW.Zhang, T.Shibamoto, Y.Kuda, C.Omukai, Y.KurataAnesthesiology.114:614-6232011年
  • Portacaval shunting attenuates portal hypertension and systemic hypotension in rat anaphylactic shockC.Kamikado, T.Shibamoto, W.Zhang, Y.Kuda, C.Omukai, Y.KurataThe journal of physiological sciences : JPS61:161-1662011年
  • Ethanol predominantly constricts pre-sinusoids of isolated perfused livers of rat, guinea pig and mouseT.Shibamoto, M.Tsutsumi, C.Omukai, Y.Kuda, W.Zhang, Y.KurataAlcohol and alcoholism : international journal of the Medical Council on Alcoholism.46:117-1222011年
  • Chained occurrences of early afterdepolarizations may create a directional triggered activity to initiate reentrant ventricular tachyarrhythmiasKunichika Tsumoto; Takao Shimamoto; Yuma Aoji; Yukiko Himeno; Yuhichi Kuda; Mamoru Tanida; Akira Amano: Yasutaka KurataComputer Methods and Programs in Biomedicine261:1085872025年04月

受賞

  • 2015年 金沢医科大学医学会 金沢医科大学医学会「論文表彰」 Major contribution of vasospasm-induced coronary blood flow reduction to anaphylactic ventricular dysfunction assessed in isolated blood-perfused rat heart.
    九田裕一
  • 2019年 金沢医科大学医学会 金沢医科大学医学会「論文表彰」 Gastric vascular and motor responses to anaphylactic hypotension in anesthetized rats, in comparison to those with hemorrhagic or vasodilator-induced hypotension
    九田 裕一

競争的資金

  • 培養HL-1心房筋細胞の実験系を用いた後脱分極誘発不整脈の発生機序と抑制法の解明
    文部科学省:科学研究費 若手研究
    研究期間:2018年 - 2020年  
    代表者:九田 裕一