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清井 武志 キヨイ タケシ

所属部署名薬理学
職名講師
 
 

研究者基本情報

学位

  • 博士(医学)

所属学協会

  • 2024年04月日本角膜学会 一般会員
  • 2021年04月眼薬理学会 一般会員
  • 2021年04月日本臨床分子形態学会 一般会員
  • 2020年04月日本薬理学会 学術評議員

研究活動情報

論文

  • CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP.Kanako Nishiyama, Masashi Maekawa, Tomoya Nakagita, Jun Nakayama, Takeshi Kiyoi, Mami Chosei, Akari Murakami, Yoshiaki Kamei, Hiroyuki Takeda, Yasutsugu Takada, Shigeki Higashiyama.Life science alliance4:e2021010952021年09月
  • PSMA-positive membranes secreted from prostate cancer cells have potency to transform vascular endothelial cells into an angiogenic state.Ryuta Watanabe, Masashi Maekawa, Takeshi Kiyoi, Mie Kurata, Noriyoshi Miura, Tadahiko Kikugawa, Shigeki Higashiyama, Takashi SaikaThe Prostate81:1390-14012021年09月
  • 島根県内の社寺林叢における陸生貝類(軟体動物門腹足綱)の生態学的評価清井 武志,秋吉 英雄ホシザキグリーン財団研究報告10:277-2872007年03月
  • Mast cell activation markers for in vitro studyMuhammad Novrizal Abdi Sahid , Takeshi KiyoiJ Immunoassay Immunochem41:778-8162020年07月
  • Inhibition of Histamine Release from RBL-2H3 Cells by Zoledronate Did Not Affect Rab27a/Doc2a Interaction.Muhammad N A Sahid, Shuang Liu, Takeshi Kiyoi, Kazutaka Maeyama, Masaki MogiBiological & pharmaceutical bulletin44:1902-19062021年08月
  • Denervation‐induced loss of skeletal muscle mass influences immune homeostasis and accelerates the disease progression of lupus nephritisShuang Liu, Takeshi Kiyoi, Erika Takemasa, Masaki MogiJCSM Clinical Reports5:108-1202020年07月
  • Dihydroxystilbenes prevent azoxymethane/dextran sulfate sodium-induced colon cancer by inhibiting colon cytokines, a chemokine, and programmed cell death-1 in C57BL/6J mice.Yoshiyuki Kimura, Maho Sumiyoshi, Takeshi Kiyoi, Kimiye BabaEuropean journal of pharmacology886:1734452020年11月
  • Assessment and Comparison of the Efficacy of Methotrexate, Prednisolone, Adalimumab, and Tocilizumab on Multipotency of Mesenchymal Stem Cells.Shuang Liu, Takeshi Kiyoi, Marina Ishida, Masaki MogiFrontiers in pharmacology11:10042020年08月
  • Constitutive hydrogen inhalation prevents vascular remodeling via reduction of oxidative stress.Takeshi Kiyoi, Shuang Liu, Erika Takemasa, Hirotomo Nakaoka, Naohito Hato, Masaki MogiPloS one15:e02275822020年04月
  • Evaluation of the structure of the otoconial layer using micro-computed tomography.Eriko Nishihara, Masahiro Okada, Takeshi Kiyoi, Masachika Shudou, Yuuki Imai, Naohito HatoAuris, nasus, larynx47:734-7392020年10月
  • Genetic Manipulation of Calcium Release-Activated Calcium Channel 1 Modulates the Multipotency of Human Cartilage-Derived Mesenchymal Stem Cells.Shuang Liu, Minae Takahashi, Takeshi Kiyoi, Kensuke Toyama, Masaki MogiJournal of immunology research2019:75102142019年02月
  • SNX9 determines the surface levels of integrin β1 in vascular endothelial cells: Implication in poor prognosis of human colorectal cancers overexpressing SNX9Kazufumi Tanigawa, Masashi Maekawa, Takeshi Kiyoi, Jun Nakayama, Riko Kitazawa, Sohei Kitazawa, Kentaro Semba, Tomohiko Taguchi, Satoshi Akita, Motohira Yoshida,Kei Ishimaru Yuji Watanabe Shigeki HigashiyamaJournal of cellular physiology234:17280-172942019年
  • High-throughput screening system for dynamic monitoring of exocytotic vesicle trafficking in mast cells.Takeshi Kiyoi, Shuang Liu, Muhammad Novrizal Abdi Sahid, Masachika Shudou, Kazutaka Maeyama, Masaki MogiPloS one133:e01987852018年07月
  • Efficacy of constant long-term delivery of YM-58483 for the treatment of rheumatoid arthritis.Maya Miyoshi, Shuang Liu, Asuka Morizane, Erika Takemasa, Yashuyuki Suzuki, Takeshi Kiyoi, Kazutaka Maeyama, Masaki MogiEuropean journal of pharmacology824:89-982018年04月
  • Inhibition of the mevalonate pathway by simvastatin interferes with mast cell degranulation by disrupting the interaction between Rab27a and double C2 alpha proteins.Muhammad Novrizal Abdi Sahid, Shuang Liu, Takeshi Kiyoi, Kazutaka MaeyamaEuropean journal of pharmacology814:255-2632017年11月
  • Efficiency and Safety of CRAC Inhibitors in Human Rheumatoid Arthritis Xenograft ModelsShuang Liu, Hitoshi Hasegawa, Erika Takemasa, Yasuyuki Suzuki, Keizou Oka, Takeshi Kiyoi, Hiroyuki Takeda, Tomio Ogasawara, Tatsuya Sawasaki, Masaki Yasukawa,Kazutaka MaeyamaJournal of immunology199:1584-15952017年09月
  • Intra-articular lentivirus-mediated gene therapy targeting CRACM1 for the treatment of collagen-induced arthritisLiu Shuang, Kiyoi Takeshi, Takemasa Erika, Maeyama KazutakaJournal of Pharmacological Sciences133:130-1382017年03月
  • The protective role of protein L-isoaspartyl (D-aspartate) O-methyltransferase for maintenance of mitochondrial morphology in A549 cell.Masahito Ogasawara, Mieko Otani, Masaoki Takano, Masachika Shudou, Yohei Inaba, Satoru Nirasawa, Saori Takahashi, Takeshi Kiyoi, Yuki Tanaka, Kenji Kameda,Naoki Kunugita Kazutaka Maeyama Keiji Sano Masahiro Yamashita Kohei YamauchiExperimental lung research42:245-2622016年06月
  • CRACM3 regulates the stability of non-excitable exocytotic vesicle fusion pores in a Ca (2+)-independent manner via molecular interaction with syntaxin4.Shuang Liu, Muhammad Novrizal Abdi Sahid, Erika Takemasa, Takeshi Kiyoi, Miyuki Kuno, Yusuke Oshima, Kazutaka MaeyamaScientific reports6:281332016年06月
  • The α4β2 nicotinic acetylcholine receptor modulates autism-like behavioral and motor abnormalities in pentylenetetrazol-kindled mice.Kenshi Takechi, Katsuya Suemaru, Takeshi Kiyoi, Akihiro Tanaka, Hiroaki ArakiEuropean journal of pharmacology775:57-662016年03月
  • Evaluation of edaravone against radiation-induced oral mucositis in miceNakajima Noriko, Watanabe Shinichi, Kiyoi Takeshi, Tanaka Akihiro, Suemaru Katsuya, Araki HiroakiJournal of Pharmacological Sciences127:339-3432015年03月
  • Involvement of stimulation of α7 nicotinic acetylcholine receptors in the suppressive effect of tropisetron on dextran sulfate sodium-induced colitis in miceTasaka Yuichi, Yasunaga Daiki, Kiyoi Takeshi, Tanaka Mamoru, Tanaka Akihiro, Suemaru Katsuya, Araki HiroakiJournal of Pharmacological Sciences127:275-2832015年03月
  • Systemic lentivirus-mediated delivery of short hairpin RNA targeting calcium release-activated calcium channel 3 as gene therapy for collagen-induced arthritis.Shuang Liu, Takeshi Kiyoi, Erika Takemasa, Kazutaka MaeyamaJournal of immunology194:76-832015年01月
  • Morphological and functional analysis of beige (Chèdiak-Higashi syndrome) mouse mast cells with giant granules.Takeshi Kiyoi, Shuang Liu, Muhammad Novrizal Abdi Sahid, Masachika Shudou, Masahito Ogasawara, Masaki Mogi, Kazutaka MaeyamaInternational immunopharmacology69:202-2122019年04月
  • Voluntary wheel-running activities ameliorate depressive-like behaviors in mouse dry eye modelKatsuya Nakano, Hitomi Nakazawa, Qiang He, Junsuke Uwada, Takeshi Kiyoi, Takaharu Ishibashi, Takayoshi MasuokaFrontiers in Behavioral Neuroscience16:01-122022年09月
  • Perinatal low-fat dietary intervention affects glucose metabolism in female adult and aging offspring(Megumi Ueno), Shuang Liu, Takeshi Kiyoi, Takashi Sugiyama, Masaki MogiGeriatrics & Gerontology International22:441-4482022年03月
  • Long-term impact of maternal dietary intervention on metabolic homeostasis in male offspring in mice(Megumi Ueno), Shuang Liu, Takeshi Kiyoi, Masaki Mogi, Takashi SugiyamaThe Journal of Nutritional Biochemistry104:1089712022年01月
  • “Intermittent environmental exposure to hydrogen prevents skin photoaging through reduction of oxidative stress.“Takeshi Kiyoi, Shuang Liu, Erika Takemasa, Naohito Hato, Masaki MogiGeriatrics & gerontology international23:3042023年02月
  • “Highly concentrated trehalose induces prohealing senescence-like state in fibroblasts via CDKN1A/p21.“(Jun Muto), Shinji Fukuda, Kenji Watanabe, Xiuju Dai, Teruko Tsuda, Takeshi Kiyoi, Kenji Kameda, Ryosuke Kawakami, Hideki Mori, Ken Shiraishi, Masamoto Murakami, Takeshi Imamura, Shigeki Higashiyama, Yasuhiro Fujisawa, Yoichi Mizukami, Koji SayamaCommunications biology6:132023年01月
  • Preventative Effect of Topical Rebamipide Against Corneal Epithelium Disorders Caused by Diclofenac SodiumFukuda Masamichi, Kiyoi Takeshi, Takeda Shun, Sasaki Yu, Masuoka Naoyoshi, Kubo Eri, Sasaki Hiroshi.J Ocul Pharmacol Ther40:428-4342024年09月
  • 角膜知覚とTRPチャネル益岡尚由、清井武志臨床眼科78:919-9252024年08月
  • Corneal acetylcholine regulates sensory nerve activity via nicotinic receptors.Takayoshi Masuoka, Takeshi Kiyoi, Shijie Zheng, Qiang He, Li Liu, Junsuke Uwada, Ikunobu MuramatsuThe Ocular Surface32:60-702024年01月
  • Morphological aberration of corneal nerves in hyposecretory dry eye guinea pigsTakeshi Kiyoi, Qiang He, Li Liu, Shijie Zheng, Hitomi Nakazawa, Junsuke Uwada, Takayoshi Masuoka.MEDICAL MOLECULAR MORPHOLOGY58:34-422025年03月
  • PIKFYVE inhibition induces endosome- and lysosome-derived vacuole enlargement via ammonium accumulationJunsuke Uwada, Hitomi Nakazawa, Takeshi Kiyoi, Takashi Yazawa, Ikunobu Muramatsu, Takayoshi MasuokaJournal of Cell Science138:2622362025年01月
  • Tear deficiency transforms spatial distribution of corneal calcitonin gene-related peptide-positive nerves in rats.Takeshi Kiyoi*, Akihiro Nakajima, Qiang He, Li Liu, Shijie Zheng, Shizuka Kobayashi, Junsuke Uwada and Takayoshi MasuokaFront Cell Neurosci19:16193102025年07月
  • 哺乳類から検出した2種類の寄生虫の形態学的・ 遺伝学的手法による種同定望月 恒太, 清井 武志, 松村 隆弘, 及川 陽三郎, 村上 学金沢医科大学雑誌50:64-692025年09月
  • The splicing factor Acin1 is essential for embryonic development but has limited effects on muscle structure and homeostasis.Mamoru Aoto, Hiroshi Sakai, Naohito Tokunaga, Mei Miyazaki, Takeshi Kiyoi, Nobutaka Ohkubo, Yuuki Imai, Noriaki Mitsuda.Scientific Reports15:140172025年04月
  • ドライアイにおける知覚異常のメカニズム益岡尚由、清井武志日本コンタクトレンズ学会誌66:50-532024年06月

書籍等出版物

  • Effect of lysed Enterococcus faecalis FK-23 as a tyndallized probiotic in allergic diseases.
    Functional Foods and Nutraceuticals in Metabolic and Non-communicable Diseases
    Kiyoi T, Shuang. Liu, Masaki Mogi.
    Elsevier 2021年01月
  • Histological Analysis of Arthritic Joints.
    Methods in Molecular Biology
    Kiyoi T
    springer nature 2018年09月
  • Histological Analyses of Arthritic Joints in Collagen-Induced Arthritis Model Mice
    Methods in Molecular Biology
    Takeshi Kiyoi
    Springer Nature 2024年01月
  • Scanning Electron Microscopic Analysis of the Bone-Resorption Activity in Mature Osteoclasts
    Methods in Molecular Biology
    Takeshi Kiyoi
    Springer Nature 2024年01月
  • Evaluation of Skin Damage Under UV Exposure
    Methods in Molecular Biology
    Takeshi Kiyoi
    Springer Nature 2024年01月
  • 外国誌要覧
    日本眼科学会雑誌
    益岡尚由、清井武志、鄭仕傑、何強、劉麗、宇和田淳介、村松育延
    日本眼科学会 2024年05月
  • Bone Resorption Activity in Mature Osteoclasts.
    Methods in Molecular Biology
    Kiyoi T
    springer nature 2018年09月

競争的資金

  • がん薬物療法副作用における角膜神経の興奮異常が眼症状に及ぼす影響
    文部科学省:科学研究費 若手研究
    研究期間:2022年 - 2024年  
    代表者:清井 武志