IINUMA Yoshitsugu

■FacultyDepartment of Infectious Diseases
■PositionProfessor

Researcher Profile & Settings

Research

    Overview of research:
    Pathophysiology of infectious diseases in immunocompromised host, Molecular epidemiology of drug resistant bacteria, Infection control and prevention

Education

  • Nagoya University

Degree

  • Ph.D in Medicine

Academic & Professional Experience

  • Mar. 2010Kanazawa Medical University Department of Infectious Diseases Professor
  • Mar. 2010Kanazawa Medical University Department of Infectious Diseases Professor

Research Activities

Published Papers

  • Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of the Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in 2019-2020: General view of the pathogens' antibacterial susceptibility, (Tokimatsu I), Matsumoto T, Tsukada H, Fujikura Y, Miki M, Morinaga Y, Sato J, Wakamura T, Kiyota H, Tateda K, Yanagisawa H, Sasaki T, Ikeda H, Horikawa H, Takahashi H, Seki M, Mori Y, Takeda H, Kurai D, Hasegawa N, Uwamino Y, Kudo M, Yamamoto M, Nagano Y, Nomura S, Tetsuka T, Hosokai M, Aoki N, Yamamoto Y, Iinuma Y, Mikamo H, Suematsu H, Maruyama T, Kawabata A, Sugaki Y, Nakamura A, Fujikawa Y, Fukumori T, Ukimura A, Kakeya H, Niki M, Yoshida K, Kobashi Y, Tokuyasu H, Yatera K, Ikegami H, Fujita M, Matsumoto T, Yanagihara K, Matsuda J, Hiramatsu K, Shinzato T., Journal of Infection and Chemotherapy, 29:731-743, 2023
  • First reported isolation of hemin-requiring Proteus vulgaris small-colony variant from urine culture., Mura T, Matsumoto T, Aso M, Kawamura K, Kanaya K, Iinuma Y, Journal of Infection and Chemotherapy, 29:631-633, 2023
  • Evaluation of Methicillin Resistance Determination Time for MRSA Using Fully Automated Rapid Identification Susceptibility testing system RAISAS S4, Miyako Aso, Kae Kawamura, Kazumi Kanaya, Tatsuki Mura, Yoshitsugu Iinuma, Journal of the Association for Rapid Method and Automation in Microbiology, 33:7-11, 2023
  • Survey report on the severe acute respiratory syndrome coronavirus 2 testing systems in Ishikawa Prefecture, (Yukie Katayama), Akiko Niikawa, Akiko Maekawa, Yoshitsugu Iinuma, 33:72-77, 2023
  • Clinical and epidemiological features of healthcare workers after a coronavirus disease 2019 cluster infection in Japan and the effects of Kampo formulas-Hochuekkito and Kakkonto: A retrospective cohort study, (Ogawa-Ochiai K), Ishikawa H, Nishimura H, Okajima M, Iinuma Y, Ito M., Medicine, 101:e29748, 2022
  • Rapid response to a coronavirus disease 2019 (COVID-19) outbreak in a psychiatry hospital—Kanazawa City, Japan, March to April 2020, (Kato H), Seki K, Maeda Y, Noda Y, Iinuma Y, Kitaoka M, Kiso K, Koshida R, Kurosu H, Yamagishi T, Shimada T, Suzuki M, Sunagawa M., Stewardship & Healthcare Epidemiology, 2:e57, 2022
  • Tocilizumab and PMX-DHP have efficacy for severe COVID-19 pneumonia., Shinomiya Shohei, Nakase Keisuke, Fujii Ai, Takahara Yutaka, Adachi Hiroki, Okuro Masashi, Iinuma Yoshitsugu, Yokoyama Hitoshi, Ito Toru, Mizuno Shiro, SAGE open medical case reports, 9:1-5, Feb. 2021
  • Evaluation of antibacterial and cytotoxic properties of a fluorinated diamond-like carbon coating for the development of antibacterial medical implants, Katsutaka Yonezawa, Masahito Kawaguchi, Ayumi Kaneuji, Toru Ichiseki, Yoshitsugu Iinuma, Kae Kawamura, Kazuhiro Shintani, Shinobu Oda, Makoto Taki, Norio Kawahara, Antibiotics (Basel), 9:495, Aug. 2020
  • Ruptured fungal aneurysm of the peripheral middle cerebral artery caused by Lomentospora infection: A case report and literature review, Sho Takata, Akira Tamase, Yasuhiko Hayashi, Kazushi Anzawa, Akihiro Shioya, Yoshitsugu Iinuma, Hideaki Iizuka, Interdisciplinary Neurosurgery, 21:100743, Sep. 2020
  • Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of japanese society of chemotherapy, the japanese association for infectious diseases, and the japanese society for clinical microbiology in 2016: General view of the pathogens' antibacterial susceptibility, (Katsunori Yanagihara), Tetsuya Matsumoto , Issei Tokimatsu , Hiroki Tsukada , Yuji Fujikura, Makoto Miki, Yoshitomo Morinaga , Junko Sato, Tomotaro Wakamura , Hiroshi Kiyota, Kazuhiro Tateda , Hideaki Hanaki , Satoru Fujiuchi, Manabu Takahashi , Hiroyuki Kayaba, Yoshiaki Mori , Hiroaki Takeda , Hideki Ikeda, Hiroshi Takahashi , Makiko Konno, Katsunao Niitsuma , Yoshihito Niki, Takahiro Takuma , Akihiko Kawana, Makoto Kudo , Tomo Hirano, Naoki Miyazawa , Sakura Aso, Nobuki Aoki , Yasuo Honma , Yoshihiro Yamamoto, Yoshitsugu Iinuma , Hiroshige Mikamo, Yuka Yamagishi, Atsushi Nakamura, Shuhei Kondo, Atsushi Kawabata , Yoshiko Sugaki , Toshinobu Yamamoto, Isao Nishi , Shigeto Hamaguchi , Hiroshi Kakeya , Yasunori Fujikawa, Noriko Mitsuno, Akira Ukimura, Koichiro Yoshida , Michio Hayashi, Keiichi Mikasa, Kei Kasahara , Hirokazu Tokuyasu, Satoshi Hino, Eiji Shimizu , Hiroki Chikumi , Masaki Fujita , Junichi Kadota, Kazufumi Hiramatsu, Moritaka Suga , Hiroyuki Muranaka, Journal of infection and chemotherapy, 26:873-881, Sep. 2020
  • Feasibility and Value of Developing an Age-stratified Antibiogram, Yoshihiro Nishita, Masatoshi Taga, Yasuhiro Kawai, Yoko Noda , Yoshiko Nakagawa, Yoshitsugu Iinuma, Osamu Niwa, 34:115-121, 2019
  • Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for clinical microbiology in 2014: General view of the pathogens' antibacterial susceptibility, (Yanagihara K), Matsumoto T, Aoki N, Sato J, Wakamura T, Kiyota H, Tateda K, Hanaki H, Ohsaki Y, Fujiuchi S, Takahashi M, Akiba Y, Masunaga S, Takeuchi K, Takeda H, Miki M, Kumagai T, Takahashi H, Utagawa M, Nishiya H, Kawakami S, Ishigaki S, Kobayasi N, Takasaki J, Mezaki K, Iwata S, Katouno Y, Inose R, Niki Y, Kawana A, Fujikura Y, Kudo M, Hirano T, Yamamoto M, Miyazawa N, Tsukada H, Aso S, Yamamoto Y, Iinuma Y, Mikamo H, Yamagishi Y, Nakamura A, Ohashi M, Kawabata A, Sugaki Y, Seki M, Hamaguchi S, Toyokawa M, Kakeya H, Fujikawa Y, Mitsuno N, Ukimura A, Miyara T, Hayasi M, Mikasa K, Kasahara K, Koizumi A, Korohasi N, Matumoto T, Yosimura Y, Katanami Y, Takesue Y, Wada Y, Sugimoto K, Yamamoto T, Kuwabara M, Doi M, Simizu S, Tokuyasu H, Hino S, Negayama K, Mukae H, Kawanami T, Yatera K, Fujita M, Kadota J, Hiramatsu K, Aoki Y, Magarifuchi H, Oho M, Morinaga Y, Suga M, Muranaka H, Fujita J, Higa F, Tateyama M, Journal of infection and chemotherapy, 25:657-668, Sep. 2019
  • Spread of seb-Positive Methicillin-Resistant Staphylococcus aureus SCCmec Type II-ST764 Among Elderly Japanese in Nonacute Care Settings., (Kawamura K), Kitaoka K, Kimura K, Wachino JI, Kondo T, Iinuma Y, Murakami N, Fujimoto S, Arakawa Y, Microbial drug resistance, 25:915-924, Mar. 2019
  • Effect of continuous skin perfusion pressure (SPP) measurement on examination results, Yumi Nakamoto, Shiho Iida, Shoutarou Murai, Yuna Hashimoto, Eiko Nishida, Keiko Yamazaki, Nao Miyakawa, Yoshitsugu Iinuma, 68:132-137, 2019
  • Characteristics of Tosufloxacin crystals and crystal casts observed in urine sediment of infants, Katsuhiro Nagata, Yoshi Tanaka, Masami Matsumoto, Aya Hashimoto, Fumina Yamaguchi, Shizuyo Nakagawa, Yoshitame Yanaida, Yoshitsugu Iinuma, 68:751-757, 2019
  • Prevalence of CTX-M-Type Extended-Spectrum β-Lactamase-Producing Escherichia coli B2-O25-ST131 H30R Among Residents in Nonacute Care Facilities in Japan., Kawamura, Kumiko. Hayashi, Kengo. Matsuo, Nao. Kitaoka, Kazuki. Kimura, Kouji. Wachino, Jun-ichi. Kondo, Takaaki. Iinuma, Yoshitsugu. Murakami, Nobuo. Fujimoto, Shuhei. Arakawa, Yoshichika., Microbial Drug Resistance, 24:　, Dec. 2018
  • Atypical lipomatous tumor in the ligamentum teres of liver: A case report and review of the literature, Usuda Daisuke, Takeshima Kento, Sangen Ryusho, Nakamura Kisuke, Hayashi Kei, Okamura Hideyuki, Kawai Yasuhiro, Kasamaki Yuji, Iinuma Yoshitsugu, Saito Htoshi, Kanda Tsugiyasu, Urashima Sachio, World Journal of Clinical Cases, 6:548-553, Oct. 2018
  • Interleukin-18 as a diagnostic marker of adult-onset Still's disease in older patients: a case report and review of the literature., Usuda Daisuke, Furumura Yoshiki, Takeshima Kento, Sangen Ryusho, Kawai Yasuhiro, Kasamaki Yuji, Iinuma Yoshitugu, Kanda Tsugiyasu., Journal of medical case reports, 12:10.1186/s13256-018-1735-7., Jul. 2018
  • Evaluation of B-type natriuretic peptide as prognostic marker in patients with pneumonia: An observational study, Daisuke Usuda , Yoshiki Furumura, Ryusho Sangen, Yu Hashimoto, Jun Kawamukai, Emiri Muranaka, Yasuhiro Kawai, Yuji Kasamaki, Yoshitsugu Iinuma, Tsugiyasu Kanda, Internal Medicine Review, 4:1-28, Mar. 2018
  • A case of extreme decrease in urinary creatinine level caused by urinary bacteria, Hideyuki Unou, Yuko Niki, Eri Yamada, Kae Kawamura, Yoshi Tanaka, Nobuyo Morita, Yoshitsugu linuma, 67:254-258, 2018
  • Procalcitonin(PCT) and Presepsin(P-SEP), Yoshitsugu linuma, Rinsho Byori, 66:1078-1086, 2018
  • Revising the Hygiene Maintenance of Urine Disposal Facilitated the Appropriate Indication of Urine Collection, NODA Yoko, IINUMA Yoshitsugu, USUDA Daisuke, TAGA Mitsutoshi, SHINMACHI Miyuki, MAEDA Kazumi, MAENO Toshiko, Japanese Journal of Environmental Infections, 32:23-28, 2017
  • Occupational Health Program in Clinical Laboratory, Yoshitsugu Iinuma, Rinsho Byori, 65:419-423, 2017
  • Practical Use of Biomarkers for Supporting Diagnosis and Treatment of Infectious Diseases, Yoshitsugu Iinuma, Rinsho Byori, 65:419-423, 2017
  • Infection prevention medical fees and microbiology laboratory, Yoshitsugu Iinuma, 63:255-261, 2017
  • Evaluation of fully automated urine particle analyzer sysmex UF-5000, Aya Hashimoto, Yoshi Tanaka, Masami Matsumoto, Katsuhiro Nagata, Shizuyo Nakagawa, Yoshitame Yanaida, Yoshitsugu Iinuma, Japanese Journal of Medical Technology, 66:255-265, 2017
  • Evaluation of automated urine particle analyzer, UF-5000, as a screening tool to identify Gram stainability of urinal pathogens, KAWAMURA Kae, IINUMA Yoshitsugu, USUDA Daisuke, HASHIMOTO Aya, MATSUMOTO Masami, TANAKA Yoshi, Japanese Journal of Medical Technology, 66:516-523, 2017
  • Performance Evaluation of the Semi-Automated Urine Chemistry Analyzer UC-1000, Y.Tanaka, M.Matsumoto, M.Yasui, R.Hokama, H.Takehara, Y.Itose, Y.Iinuma, Sysmex Journal International, 27:1, 2017
  • Gastroenteritis in Japanese Females Caused by Shigella flexneri without Definite. Infection Route: A Case Report and Mini-Review of Literature, Daisuke Usuda, Shinya Yamada, Kento Takeshima, Ryusho Sangen, Masaharu Iguchi, Yasuhiro Kawai, Yuji Kasamaki, Yoshitsugu Iinuma and Tsugiyasu Kanda, Journal Clinical Case Reports, 7:10001021　, 2017
  • Middle East Respiratory Syndrome(MERS), Y.Iinuma, The Official Journal of Japanese Society of Laboratory Medicine, 64:1044-1051, Sep. 2016
  • Usability by the colorimetric method for measurement of chlorine concentration in hypochlorite solutions and factors for change of the concentration, M.Taga, D.Usuda, Y.Noda, Y.Iinuma, Y.Nishita, Y.Yamamoto, O.Niwa, Japanese Journal of Environmental Infections, 31:314-317, Sep. 2016
  • A case of 2,8-dihydroxyadenine crystal urine that did not show urine calculus, K.Nagata, Y.Tanaka, M.Matsumoto, C.Tanaka, K.Nitta, K.Miyazawa, Y.Iinuma, Japanese Journal of Medical Technology, 65:695-699, Jun. 2016
  • Autopsy-proven intravascular lymphoma presenting as rapidly recurrent strokes, D.Usuda, M.Arahata, R.Temaru, Y.Iinuma, T.Kanda, S.Hayashi, Case reports in oncology, 9:148-153, Mar. 2016
  • Applying a PCR-based open-reading frame typing method for easy genotyping and molecular epidemiological analysis of Pseudomonas aeruginosa., (M.Suzuki), K.Yamada, M.Aoki, E.Hosoba, M.Matsumoto, H.Baba, Y.Iinuma, Journal of applied microbiology, 120:487-497, Feb. 2016
  • Validation of a B-type natriuretic peptide as a prognostic marker in pneumonia patients: a prospective cohort study., D.Usuda, R.Sangen, Y.Hashimoto, E.Muranaka, Y.Iinuma, T.Kanda, BMJ open, 6:e010440-e010440, Feb. 2016
  • Risk factors for nosocomial tuberculosis transmission among health care workers., (Y.Ito), M.Nagao. Y.Iinuma, Y.Matsumura, M.Yamamoto, S.Takakura, J.Igawa, H.Yamanaka, A.Hashimoto, T.Hirai, A.Niimi, S.Ichiyama, M.Mishima, American journal of infection control, 44:596-598, Jan. 2016
  • Management of infectious complications in solid-organ transplant recipients, Y.Iinuma, The Journal of the Japanese Society for Clinical Microbiology, 26:11-23, Jan. 2016
  • Fundamental assessment of the chemiluminescent enzyme immunoassay measurement reagent Lumipulse HBsAg-HQ, N.Yoshino, E.Yamada, K.Enda, H.Baba, Y.Iinuma, Japanese Journal of Medical Technology, 65:91-97, 2016
  • Four pediatric cases of ammonium acid urate crystal with nephrotic syndrome, M.Matsumoto, Y.Tanaka, C.Tanaka, S.Nakagawa, Y.Yanaida, K.Nagata, T.Fujiki, Y.Iinuma, The Japanese journal of medical technology, 64:541-547, Sep. 2015
  • Changes in surgical site infections after living donor liver transplantation, (M.Yamamoto), S.Takakura, Y.Iinuma, G.Hotta, Y.Matsumura, A.Matsushima, M.Nagao, K.Ogawa, Y.Fujimoto, A.Mori, Y.Ogura, T.Kaido, S.Uemoto, S.Ichiyama, PLoS One, 10:e0136559-e0136559, Aug. 2015
  • Causes of presence of ammonium urate crystals in urinary sediments, Y.Tanaka, M.Matsumoto, C.Tanaka, S.Nakagawa, Y.Yanaida, K.Nagata, Y.Iinuma, The Japanese journal of medical technology, 64:179-185, Jan. 2015
  • Points of revision of the guideline JSLM 2012, (A.Suwabe), M.Maekawa, M.Koshiba, H.Baba, Y.Iinuma, K,Izuhara, Y.Furukawa, Y.Tanaka, K,Furuichi, T.Wada, H.Yoshida, H.Harigae, N.Watanabe, I.Kitajima, 62:702-709, 2014
  • Fundamental assessment of the CHROMagarTM MDRP medium in the screening of multidrug-resistant Pseudomonas aeruginosa, K.Matsuura, H.Baba, M.Asou, E.Morita, K.Kanaya, K.Kawamura, Y.Iinuma, 63:226-231, 2014
  • Pneumocystis polymerase chain reaction and blood (1→3)-β-D-glucan assays to predict survival with suspected Pneumocystis jirovecii pneumonia., (Y.Matsumura), Y.Ito, M.Yamamoto, A.Matsushima, M.Nagao, S.Takakura, Y.Iinuma, S.Ichiyama, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy., 20:109-114, 2014
  • Fundamental　assessment　of　chemiluminescent　enzyme　immunoassay　measurement　reagent Lumipulse　HBcAb-N"", N.Yoshino, Y.Asai, E.Yamada, K.Enda, H.Baba, Y.Iinuma, 62:314-318, Mar. 2013
  • Genetic relatedness of Mycobacterium avium-intracellulare complex isolates from patients with pulmonary MAC disease and their residential soils., (K.Fujita), Y.Ito, T.Hirai, K.Maekawa, S.Imai, S.Tatsumi, A.Niimi, Y.Iinuma, S.Ichiyama, M.Mishima, Clinical microbiology and infection, 19:537-541, Jan. 2013
  • Enterococcus, Y.Iinuma, 70:213-218, 2012
  • Regional spread and control of vancomycin-resistant Enterococcus faecium and Enterococcus faecalis in Kyoto, Japan, (A.Matsushima), S.Takakura, M.Yamamoto, Y.Matsumura, M.Shirano, M.Nagao, Y.Ito, Y.Iinuma, T.Shimizu, N.Fujita, S.Ichiyama, European journal of clinical microbiology & infectious diseases, 31:1095-1100, 2011
  • Quantitative real-time PCR and the (1→3)-β-D-glucan assay for differentiation between Pneumocystis jirovecii pneumonia and colonization, (Y.Matsumura), Y.Ito, Y.Iinuma, K.Yasuma, M.Yamamoto, A.Matsushima, M.Nagao, S.Takakura, S.Ichiyama, Clinical microbiology and infection, 18:591-597, 2011
  • Environmental risk factors for pulmonary Mycobacterium avium-intracellulare complex disease, (K.Maekawa), Y.Ito, T.Hirai, T.Kubo, S.Imai, S.Tatsumi, K.Fujita, S.Takakura, A.Niimi, Y.Iinuma, S.Ichiyama, K.Togashi, M.Mishima, American College of Chest Physicians, 140:723-729, 2011
  • Distribution and clonal relationship of cell surface virulence genes among streptococcus pneumoniae isolates in Japan, (S.Imai), Y.Ito, T.Ishida, T.Hirai, I.Ito, K.Yoshimura, K.Maekawa, S.Takakura, A.Niimi, Y.Iinuma, S.Ichiyama, M.Mishima, the Kansai Community Acquired Pneumococcal Pneumonia Study Group, Clinical microbiology and infection, 17:1409-1414, 2011
  • Control of an outbreak of carbapenem-resistant Pseudomonas aeruginosa in a haemato-oncology unit, (M.Nagao), Y.Iinuma, J.Igawa, T.Saito, K.Yamashita, T.Kondo, A.Matsushima, S.Takakura, A.Takaori-Kondo, S.Ichiyama, The Journal of hospital infection., 79:49-53, 2011
  • Clinical characteristics of pneumocystis pneumonia in non-HIV patients and prognostic factors including microbiological genotypes, (Y.Matsumura), Y.Shindo, Y.Iinuma, M.Yamamoto, M.Shirano, A.Matsushima, M.Nagao, Y.Ito, S.Takakura, Y.Hasegawa, S.Ichiyama, BMC infectious diseases [electronic resource], 11:76,1-9, 2011
  • Antimicrobial ointments and methicillin-resistant Staphylococcus aureus USA300, (M.Suzuki), K.Yamada, M.Nagao, E.Aoki, M.Matsumoto, T.Hirayama, H.Yamamoto, R.Hiramatsu, S.Ichiyama, Y.Iinuma, Emerging infectious diseases., 17:1917-1920, 2011
  • A case in which planned reoperation was useful for infected pancreatic necrosis with duodenal perforation, Siko Miura, Nobuhiko Ueda, Daisuke Kaida, Takashi Miyata, Tomoharu Miyashita, Hideto Fujita, Hiroyuki Takamura, Yoshitsugu Iinuma, 13:57-61, Apr. 2023
  • Olfactory and taste dysfunctions caused by COVID-19: a nationwide study, Takaki MIwa, Eri Mori, Rumi Sekine, Yurika Kimura, Masayoshi Kobayashi, Hideaki Shiga, Kenzo Tsuzuki, Motohiko Suzuki, Kenji Kondo, Isao Suzaki, Go Inokuchi, Tsunemasa Aiba, Kyoko Chujo, Sayaka Yagi-Nakanishi, Toshiaki Tsukatani, Hiroki Nakanishi, Muneko Nishijyo, Yoshitsugu Iinuma, Akihito Yokoyama, Rhinology, 61:552-560, Jan. 2023