MATSUI Tadashi

Researcher Profile & Settings

Research

Overview of research:
Functional analysis of p53-binding proteins in DNA damage response

Education

• Tokyo Institute of Technology Graduate School Division of Life Science and Engineering
• Tokyo Institute of Technology Faculty of Science

Degree

• Doctor(Science)

Research Activities

Published Papers

• Camptothecin compromises transcription recovery and cell survival against cisplatin and ultraviolet irradiation regardless of transcription-coupled nucleotide excision repair, Ryo Sakasai, Mitsuo Wakasugi, Tadashi Matsui, Yumi Sunatani, Masafumi Saijo, Tsukasa Matsunaga, Kuniyoshi Iwabuchi, DNA Repair, 113:103318, Mar. 2022
  DOI:10.1016/j.dnarep
• Caspase-mediated cleavage of X-ray repair cross-complementing group 4 promotes apoptosis by enhancing nuclear translocation of caspase-activated DNase., Yumi.Sunatani, Radhika Pankaj Kamdar, Mukesh Kumar Sharma, Tadashi.Matsui, Ryo.Sakasai, Mitsumasa.Hashimoto, Yasuhito.Ishigaki, Yoshihisa.Matsumoto, Kuniyoshi.Iwabuchi, Experimental cell research, 362:450, Jan. 2018
  DOI:10.1016/j.yexcr.2017.12.009
• Knockdown of stromal interaction molecule 1 (STIM1) suppresses store-operated calcium entry, cell proliferation and tumorigenicity in human epidermoid carcinoma A431 cells, J.Yoshida, K.Iwabuchi, T.Matsui, T.Ishibashi, T.Masuoka, M.Nishio, Biochemical pharmacology., 84:1592-1603, Sep. 2012
• PKU-β/TLK1　regulates myosin Ⅱ activities, and is required for accurate equaled chromosome segregation, M.Hashimoto, T.Matsui, K.Iwabuchi, T.Date, Mutation research, 657:63-67, Sep. 2008
• Characterization of a cancer cell line that expresses a splicing variant form of 53BP1:Separation of checkpoint and repair functions in 53BP1, K.Iwabuchi, T.Matsui, M.Hashimoto, Y.Matsumoto, T.Kurihara, T.Date, Biochemical and biophysical research communications, 376:509-513, Sep. 2008
• Cell sorting analysis of cell cycle-dependent X-ray sensitivity in end joining-deficient human cells, K.Iwabuchi, M.Hashimoto, T.Matsui, A.Kurosawa, N.Adachi, T.Date, Biochemical and biophysical research communications, 372:662-667, May 2008
• 53BP1 contributes to survival of cells irradiated with X-ray during G1 without Ku70 or Artemis., K.Iwabuchi, M.Hashimoto, T.Matsui, T.Kurihara, H.Shimizu, N.Adachi, M.Ishiai, K-I.Yamamoto, H.Tauchi, M.Takata, H.Koyama, T.Date, Genes to cells : devoted to molecular & cellular mechanisms, 11: 935-948, Aug. 2006
• Hepatitis C virus core protein interacts with p53-bindinng protein,53BP2/Bbp/ASPP2,and inhibits p53-mediated apoptosis, Y.Cao, T.Hamada, T.Matsui, T.Date, K.Iwabuchi, Biochem. Biophys. Res. Commun., 315：788-795, 2004
• Expression of unphosphorylated form of human double-stranded RNA-activated protein kinase in Escherichia coli, T. Matsui, K. Tanihara, T. Date, Biochem. Biophys. Res. Commun., 284: 798-807, 2001
• UbcH5c-dependent activation of DNA-dependent protein kinase in response to replication-mediated DNA double-strand breaks, Ryo Sakasai, Tadashi Matsui, Yumi Sunatani, Kuniyoshi Iwabuchi, Biochemical and Biophysical Research Communications, 668:42-48, Aug. 2023
  DOI:10.1016/j.bbrc.2023.05.068.
• 53BP1 regulates the self-renewal ability of neural stem/progenitor cells through modulating mitochondrial homeostasis, Yumi Sunatani, Ryo Sakasai, Tadashi Matsui, Kuniyoshi Iwabuchi, Biochemical and Biophysical Research Communications, 734:150776, Oct. 2024