YOKOYAMA Hitoshi

FacultyDepartment of Nephrology
PositionProfessor

Researcher Profile & Settings

Research

    Overview of research:
    We study widely on nephrology field including glomerulonephritis, nephrotic syndrome, acute and chronic renal failure and transplant related nephropathy. In addition, we study the clinical application of blood purification on refractory diseases including renal diseases, autoimmune diseases and systemic inflammatory diseases.

Education

  • Kanazawa University Graduate School

Degree

  • Ph.D in Medicine

Association Memberships

  • 1993American Society of Nephrology member

Academic & Professional Experience

  • Aug. 1992Aug. 1993Harvard Medical School Lecturer on medicine

Research Activities

Published Papers

  • Changes in Double-Strand DNA Breaks Predict Delayed Graft Function (DGF) in Japanese Renal Allograft Recipients, Keiichiro Okada, Kanae Nomura-Nakayama, Yuki Okushi, Kazuaki Okino, Kiyotaka Mukai, Norifumi Hayashi, Keiji Fujimoto, Hiroki Adachi, Hitoshi Yokoyama, Clinical and Experimental Nephrology24:96-104Jan. 2020
  • Plasma exchange for thrombotic microangiopathy secondary to dermatomyositis associated with acute kidney injury and complement activation: a case report with literature review, Norifumi Hayashi, Keiichirou Okada, Yuko Tsuruyama, Yu Kagaya, Sho Kumano, Yuki Ishikura,Kiminobu Takeda, Masayuki Nanbu, Keiji Fujimoto, Hiroki Adachi, Hitoshi Yokoyama, Renal Replacement Therapy5:48Dec. 2019
  • Recent Clinicopathological Findings of Kidney Disease in Diabetes Cases, Kengo Furuichi, Hitoshi Yokoyama, Journal of Kanazawa Medical University44:117-121Dec. 2019
  • Association of renal arteriosclerosis and hypertension with renal and cardiovascular outcomes in Japanese type 2 diabetes patients with diabetic nephropathy, (Shimizu, M), Furuichi, K, Toyama, T, Funamoto, T, Kitajima, S, Hara, A, Iwata, Y, Sakai, N, Takamura, T, Kitagawa, K, Yoshimura, M, Kaneko, S, Yokoyama, H, Wada, T, Journal of diabetes investigation10:1041-1049Jul. 2019
  • Update of Findings of Hepatitis C Virus Infection in Renal Allograft Recipients, Kazuaki Okino, Yuki Okushi, Kiyotaka Mukai, Norifumi Hayashi, Keiji Fujimoto, Hiroki Adachi, Hitoshi Yokoyama, Journal of Kanazawa Medical University44:7-13Jun. 2019
  • A case of apolipoprotein E Toyonaka and homozygous apolipoprotein E2/2 showing non-immune membranous nephropathy-like glomerular lesions with foamy changes, (Kato T), Ushiogi Y, Yokoyama H, Hara S, Matsunaga A, Muso E, Saito T, CEN Case Reports8:106-111May. 2019
  • Nonproteinuric Versus Proteinuric Phenotypes in Diabetic Kidney Disease: A Propensity Score-Matched Analysis of a Nationwide, Biopsy-Based Cohort Study, (Yamanouchi M), Furuichi K, Hoshino J, Toyama T, Hara A, Shimizu M, Kinowaki K, Fujii T, Ohashi K, Yuzawa Y, Kitamura H, Suzuki Y, Sato H, Uesugi N, Hisano S, Ueda Y, Nishi S, Yokoyama H, Nishino T, Samejima K, Kohagura K, Shibagaki Y, Mise K, Makino H, Matsuo S, Ubara Y, Wada T, Diabetes Care42:891-902May. 2019
  • Amplified Association Between Blood Pressure and Albuminuria in Overweight Patients With Biopsy-Proven Hypertensive Nephrosclerosis, (Kohagura K), Furuichi K, Kochi M, Shimizu M, Yuzawa Y, Hara A, Toyama T, Kitamura H, Suzuki Y, Sato H, Uesugi N, Ubara Y, Hoshino J, Hisano S, Ueda Y, Nishi S, Yokoyama H, Nishino T, Ogawa D, Mise K, Shibagaki Y, Kimura K, Haneda M, Makino H, Matsuo S, Wada T, American Journal of Hypertension32:486-491Apr. 2019
  • Epidemiology and prognosis of IgA nephropathy in Japan, Hitoshi Yokoyama77:593-597Apr. 2019
  • Distribution of nephrologists and regional variation in the clinical severity of IgA nephropathy at biopsy diagnosis in Japan: a cross-sectional study, Okabayashi Y, Tsuboi N, Amano H, Miyazaki Y, Kawamura T, Ogura M, Narita I, Ninomiya T, Yokoyama H, Yokoo T, BMJ Open8:1-8Nov. 2018
  • Renal response to anaphylaxis in anesthetized rats and isolated perfused rat kidneys: roles of nitric oxide., Mukai K, Kuda Y, Shibamoto T, Tanida M, Kurata Y, Yokoyama H., The Journal of Physiological Sciences68:689-697Sep. 2018
  • Clinical features and pathogenesis of membranoproliferative glomerulonephritis: a nationwide analysis of the Japan renal biopsy registry from 2007 to 2015, Nakagawa N, Hasebe N, Hattori M, Nagata M, Yokoyama H, Sato H, Sugiyama H, Shimizu A, Isaka Y, Maruyama S, Narita I, Clinical and Experimental Nephrology22:797-807Aug. 2018
  • Clinicopathological analysis of biopsy-proven diabetic nephropathy based on the Japanese classification of diabetic nephropathy, Furuichi K, Shimizu M, Yuzawa Y, Hara A, Toyama T, Kitamura H, Suzuki Y, Sato H, Uesugi N, Ubara Y, Hohino J, Hisano S, Ueda Y, Nishi S, Yokoyama H, Nishino T, Kohagura K, Ogawa D, Mise K, Shibagaki Y, Makino H, Matsuo S, Wada T, Clinical and Experimental Nephrology22:570-582Jun. 2018
  • Nationwide multicenter kidney biopsy study of Japanese patients with hypertensive nephrosclerosis, Furuichi K, Shimizu M, Yuzawa Y, Hara A, Toyama T, Kitamura H, Suzuki Y, Sato H, Uesugi N, Ubara Y, Hoshino J, Hisano S, Ueda Y, Nishi S, Yokoyama H, Nishino T, Kohagura K, Ogawa D, Mise K, Shibagaki Y, Kimura K, Haneda M, Makino H, Matsuo S, Wada T, Clinical and Experimental Nephrology22:629-637Jun. 2018
  • Rationale and study design of a clinical trial to assess the effects of LDL apheresis on proteinuria in diabetic patients with severe proteinuria and dyslipidemia, Wada T, Muso E, Maruyama S, Hara A, Furuichi K, Yoshimura K, Miyazaki M, Sato E, Abe M, Shibagaki Y, Narita I, Yokoyama H, Mori N, Yuzawa Y, Matsubara T, Tsukamoto T, Wada J, Ito T, Masutani K, Tsuruya K, Fujimoto S, Tsuda A, Suzuki H, Kasuno K, Terada Y, Nakata T, Iino N, Kobayashi S, Clinical and Experimental Nephrology22:591-596Jun. 2018
  • High molecular weight adiponectin inhibits vascular calcification in renal allograft recipients, Nomura-Nakayama K, Adachi H, Miyatake N, Hayashi N, Fujimoto K, Yamaya H, Yokoyama H, PLoS One13:e0195066May. 2018
  • Decline in estimated glomerular filtration rate is associated with risk of end-stage renal disease in type 2 diabetes with macroalbuminuria: an observational study from JDNCS, (Miho.Shimizu), Kengo.Furuichi, Tadashi.Toyama, Tomoaki.Funamoto, Shinji.Kitajima, Akinori.Hara, Daisuke.Ogawa, Daisuke.Koya, Kenzo.Ikeda, Yoshitaka.Koshino, Yukie.Kurokawa, Hideharu.Abe, Kiyoshi.Mori, Masaaki.Nakayama, Yoshio.Konishi, Ken-ichi.Samejima, Masaru.Matsui, Hiroyuki.Yamauchi, Tomohito.Gohda, Kei.Fukami, Daisuke.Nagata, Hidenori.Yamazaki, Yukio.Yuzawa, Yoshiki.Suzuki, Shouichi.Fujimoto, Shoichi.Maruyama, Sawako.Kato, Takero.Naito, Kenichi.Yoshimura, Hitoshi.Yokoyama, Takashi.Wada, Research Group of Diabetic Nephropathy, The Ministry of Health, Labour, and Welfare of Japan and Japan Agency for Medical Research and Development, Clinical and Experimental Nephrology22:377-387Apr. 2018
  • Nationwide multicentre kidney biopsy study of Japanese patients with type 2 diabetes, Furuichi K, Yuzawa Y, Shimizu M, Hara A, Toyama T, Kitamura H, Suzuki Y, Sato H, Uesugi N, Ubara Y, Hisano S, Ueda Y, Nishi S, Yokoyama H, Nishino T, Kohagura K, Ogawa D, Mise K, Shibagaki Y, Kimura K, Haneda M, Makino H, Matsuo S, Wada T, NEPHROLOGY DIALYSIS TRANSPLANTATION33:138-148Jan. 2018
  • Glomerular mannose-binding lectin deposition in intrinsic antigen-related membranous nephropathy, N.Hayashi, K.Okada, Y.Matsui, K.Fujimoto, H.Adachi, H.Yamaya, M.Matsushita, H.Yokoyama, NEPHROLOGY DIALYSIS TRANSPLANTATION33:832-8402018
  • Circulating and renal expression of HLA-G prevented chronic renal allograft dysfunction in Japanese recipients, Okushi Y, Okino K, Mukai K, Matsui Y, Hayashi N, Fujimoto K, Adachi H, Yamaya H, Yokoyama H, Clinical and Experimental Nephrology21:932-940Mar. 2017
  • The long-term outcomes of hepatitis C virus core antigen-positive Japanese renal allograft recipients, K.Okino, Y.Okushi, K.Mukai, Y.Matsui, N.Hayashi, K.Fujimoto, H.Adachi, H.Yamaya, H.Yokoyama, Clinical and Experimental Nephrology21:1113-1123Mar. 2017
  • The clinical and pathological characteristics of nephropathies in connective tissue diseases in the Japan Renal Biopsy Registry (J-RBR), (Ichikawa K), Konta T, Sato H, Ueda Y, Yokoyama H, Clinical and Experimental Nephrology21:1024-1029Mar. 2017
  • A patient with tuberous sclerosis in whom dialysis was introduced due to hemorrhaging from oncocytic papillary renal cell carcinoma, Keiji.Fujimoto, Masaru.Nakagawa, Katsuaki.Sato, Tatsuro.Tanaka, Nobuhiko.Miyatake, Keita.Yamazaki, Yuko.Tsuruyama, Yuki.Okushi, Kazuaki.Okino, Kiyotaka.Mukai, Katsuhito.Miyazawa, Hitoshi.Yokoyama, Journal of Japanese Society for Dialysis Therapy50:93-100Jan. 2017
  • Mizoribine therapy combined with steroids and mizoribine blood concentration monitoring for idiopathic membranous nephropathy with steroid-resistant nephrotic syndrome, (Saito T), Iwano M, Matsumoto K, Mitarai T, Yokoyama H, Yorioka N, Nishi S, Yoshimura A, Sato H, Ogahara S, Sasatomi Y, Kataoka Y, Ueda S, Koyama A, Maruyama S, Nangaku M, Imai E, Matsuo S, Tomino Y, Clinical and Experimental Nephrology21:961-9702017
  • Clinical and histological features of lupus nephritis in Japan: A cross-sectional analysis of the Japan Renal Biopsy Registry (J-RBR), (Hiromura K), Ikeuchi H, Kayakabe K, Sugiyama H, Nagata M, Sato H, Yokoyama H, Nojima Y, Nephrology (Carlton)22:885-8912017
  • A clinical evaluation of renal amyloidosis in the Japan renal biopsy registry: a cross-sectional study, (Nishi S), Muso E, Shimizu A, Sugiyama H, Yokoyama H, Ando Y, Goto S, Fujii H, Clinical and Experimental Nephrology21:624-6322017
  • Performance in adolescents of the two Japanese serum creatinine based estimated glomerular filtration rate equations, for adults and paediatric patients: A study of the Japan Renal Biopsy Registry and Japan Kidney Disease Registry from 2007 to 2013, (Uemura O), Yokoyama H, Ishikura K, Gotoh Y, Sato H, Sugiyama H, Honda M, Matsuo S, Nephrology (Carlton)22:494-4972017
  • Clinical manifestations of Henoch-Schönlein purpura nephritis and IgA nephropathy: comparative analysis of data from the Japan Renal Biopsy Registry (J-RBR), (H.Komatsu), S.Fujimoto, N.Yoshikawa, H.Kitamura, H.Sugiyama, H.Yokoyama, Clinical and experimental nephrology20:552-560Aug. 2016
  • Drug-induced kidney disease: a study of the Japan Renal Biopsy Registry from 2007 to 2015., H.Yokoyama, I.Narita, H.Sugiyama, M.Nagata, H.Sato, Y.Ueda, S.Matsuo, Clinical and experimental nephrology20:720-7302016
  • Clinical practice guideline for drug-induced kidney injury in Japan 2016: digest version, (J.Usui), K.Yamagata, E.Imai, H.Okuyama, H.Kajiyama, H.Kanamori, S.Kaneko, E.Kono, Y.Sakai, N.Sakai, Y.Sakamaki, Y.Taniguchi, K.Nakai, H.Nishiwaki, S.Hirata, H.Yamaya, S.Tsuruoka, Y.Terada, H.Yokoyama, T.Wada, I.Narita, Clinical and experimental nephrology20:827-8312016
  • Adiponectin Fractions Influence the Development of Posttransplant Diabetes Mellitus and Cardiovascular Disease in Japanese Renal Transplant Recipients, H.Adachi, K.Nakayama, N.Hayashi, Y.Matsui, K.Fujimoto, H.Yamaya, H.Tonami, H.Yokoyama, PLoS one11:e0163899-e01638992016
  • Clinicopathological characteristics of M-type phospholipase A2 receptor (PLA2R)-related membranous nephropathy in Japanese, N.Hayashi, S.Akiyama, H.Okuyama, Y.Matsui, H.Adachi, H.Yamaya, S.Maruyama, E.Imai, S.Matsuo, H.Yokoyama, Clinical and Experimental Nephrology19:797-803Oct. 2015
  • DNA double-strand breaks induced intractable glomerular fibrosis in renal allografts, Y.Matsui, Y.Sunatani, N.Hayashi, K.Okino, Y.Okushi, K.Mukai, H.Adachi, H.Yamaya, K.Iwabuchi, H.Yokoyama, Clinical and Experimental Nephrology20:479-488Sep. 2015
  • Effects of serum albumin and glycated albumin levels on performance of the Japanese GFR equation based on serum cystatin C, (M.Horio), E.Imai, Y.Yasuda, T.Watanabe, H.Yokoyama, H.Makino, S.Matsuo, Clinical and Experimental Nephrology19:626-630Aug. 2015
  • Clinical significance of serum and urinary soluble urokinase receptor (suPAR) in primary nephrotic syndrome and MPO-ANCA-associated glomerulonephritis in Japanese, K.Fujimoto, J.Imura, H.Atsumi, Y.Matsui, H.Adachi, H.Okuyama, H.Yamaya, H.Yokoyama, Clinical and Experimental Nephrology19:804-814Aug. 2015
  • A prospective observational survey on the long-term effect of LDL apheresis on drug-resistant nephrotic Syndrome, (E. Muso), M.Mune, T.Hirano, M.Hattori, K.Kimura, T.Watanabe, H.Yokoyama, H.Sato, S.Uchida, T.Wada, T.Shoji, T.Takemura, Y.Yuzawa, S.Ogahara, S.Sugiyama, Y.Iino, S.Sakai, Y.Ogura, S.Yukawa, Y.Nishizawa, N.Yorioka, E.Imai, S.Matsuo, T.Saito, Nephron Extra5:58-66Aug. 2015
  • The influences of larger physical constitutions including obesity on the amount of urine protein excretion in primary glomerulonephritis: research of the Japan Renal Biopsy Registry, (Y.Yonekura), S.Goto, H.Sugiyama, H.Kitamura, H.Yokoyama, S.Nishi, Clinical and Experimental Nephrology19:359-370Jun. 2015
  • Outcomes of primary nephrotic syndrome in elderly Japanese: retrospective analysis of the Japan Renal Biopsy Registry (J-RBR), H.Yokoyama, H.Sugiyama, i.Narita, T.Saito, K.Yamagata, S.Nishio, S.Fujimoto, N.Mori, Y.Yuzawa, S.Okuda, S.Maruyama, H.Sato, Y.Ueda, H.Makino, S.Matsuo, Clinical and Experimental Nephrology19:496-505Jun. 2015
  • Immediate therapeutic efficacy of low-density lipoprotein apheresis for drug-resistant nephrotic syndrome: evidence from the short-term results from the POLARIS Study, (Muso, Eri);Mune, Masatoshi;Hirano, Tsutomu;Hattori, Motoshi;Kimura, Kenjiro;Watanabe, Tsuyoshi;Yokoyama, Hitoshi;Sato, Hiroshi;Uchida, Shunya;Wada, Takashi;Shoji, Tetsuo;Yuzawa, Yukio;Takemura, Tsukasa;Sugiyama, Satoshi;Nishizawa, Yoshiki;Ogahara, Satoru;Yorioka, Noriaki;Sakai, Soichi;Ogura, Yosuke;Yukawa, Susumu;Iino, Yasuhiko;Imai, Enyu;Matsuo, Seiichi;Saito, Takao, Clinical and Experimental Nephrology19:379-386Jun. 2015
  • Serum albumin, but not glycated albumin was a potent factor affecting the performance of GFR equation based on serum creatinine, (M.Horio), E.Imai, Y.Yasuda, T.Watanabe, H.Yokoyama, H.Makino, S.Matsuo, Clinical and Experimental Nephrology19:284-292Apr. 2015
  • Serum tau protein as a marker of disease activity in enterohemorrhagic Escherichia coli O111-induced hemolytic uremic syndrome, (M.Kuroda), M.Shimizu, N.Inoue, I.Ikeno, H.Nakagawa, A.Yokoi, Y.Niida, M.Konishi, H.Kaneda, N.Igarashi, J.Yamahana, H.Taneichi, H.Kanegane, M.Ito, S.Saito, K.Furuichi, T.Wada, M.Nakagawa, H.Yokoyama, A.Yachie, Neurochemistry International85-86:24-302015
  • Relapse and its remission in Japanese patients with idiopathic membranous nephropathy, (S.Kitajima), K.Furuichi, N.Sakai, A.Sagara, Y.Shinozaki, T.Toyama, Y.Iwata, M.Shimizu, H.Yokoyama, S.Kaneko, T.Wada, Clinical and Experimental Nephrology19:278-2832015
  • Different association of cigarette smoking with GFR estimated from serum creatinine and that from serum cystatin C in the general population, Y.Yamada, Y.Noborisaka, M.Ishizaki, M.Yamazaki, R.Honda, H.Yokoyama, T.Kakuma, Clinical and Experimental Nephrology19:669-6772015
  • Case of cutaneous phaeohyphomycosis caused by Phaeoacremonium sp. in a renal transplant recipient, Y.Sakata, A.Kitayama, R.Yoshimura, K.Anzawa, T.Fujii, K.Fujimoto, H.Yokoyama, T.Mochizuki, Journal of Dermatology42:263-2662015
  • Comparison of the antialbuminuric effects of benidipine and hydrochlorothiazide in Renin-Angiotensin System (RAS) inhibitor-treated hypertensive patients with albuminuria: the COSMO-CKD (COmbination Strategy on Renal Function of Benidipine or Diuretics TreatMent with RAS inhibitOrs in a Chronic Kidney Disease Hypertensive Population) study, (K.Ando), K.Nitta, H.Rakugi, Y.Nishizawa, H.Yokoyama, T.Nakanishi, N.Kashihara, K.Tomita, M.Nangaku, K.Takahashi, M.Isshiki, T.Shimosawa, T.Fujita, International journal of medical sciences [electronic resource]11:897-904: May. 2014
  • A multicenter cross-sectional study of circulating soluble urokinase receptor in Japanese patients with glomerular disease, (T.Wada), M.Nangaku, S.Maruyama, E.Imai, K.Shoji, S.Kato, T.Endo, E.Muso, K.Kamata, H.Yokoyama, K.Fujimoto, Y.Obata, T.Nishino, H.Kato, S.Uchida, Y.Sasatomi, T.Saito, S.Matsuo, Kidney international.85:641-648Jan. 2014
  • Significance of combined cyclosporine-prednisolone therapy and cyclosporine blood concentration monitoring for idiopathic membranous nephropathy with steroid-resistant nephrotic syndrome: a randomized controlled multicenter trial, (T.Saito), M.Iwano, K.Matsumoto, T.Mitarai, H.Yokoyama, N.Yorioka, S.Nishi, A.Yoshimura, H.Sato, S.Ogahara, H.Shuto, Y.Kataoka, S.Ueda, A.Koyama, S.Maruyama, M.Nangaku, E.Imai, S.Matsuo, Y.Tomino, Clinical and experimental nephrology18:784-794Dec. 2013
  • Epidemiological and clinicopathological studies based on web registration system(J-RBR/J-KDR), H.Yokoyama26:37-43Nov. 2013
  • Kidney lesions in diabetic patients with normoalbuminuric renal insufficiency, (M.Shimizu), K.Furuichi, H.Yokoyama, T.Toyama, Y.Iwata, N.Sakai, S.Kaneko, T.Wada, Clinical and experimental nephrology18:305-312Oct. 2013
  • Adult-onset renal failure in a family with Alagille syndrome with proteinuria and a novel JAG1 mutation., N.Hayashi, H.Okuyama, Y.Matsui, H.Yamaya, E.Kinoshita, H.Minato, Y.Niida, H.Yokoyama, Clinical kidney journal.6:295-299Mar. 2013
  • A patient with persistent renal AL amyloid deposition after clinical remission by HDM/SCT therapy., H.Okuyama, H.Yamaya, T.Fukushima, H.Yokoyama, Clinical nephrology.79:233-236Mar. 2013
  • Successful delivery in a patient with antineutrophil cytoplasmic antibody-associated glomerulonephritis., (M.Oshima), S.Kitajima, T.Toyama, A.Hara, K.Kitagawa, Y.Iwata, M.Shimizu, S.Nishio, J.Imura, H.Yokoyama, K.Furuichi, S.Kaneko, T.Wada, Internal medicine (Tokyo, Japan)52:1605-1609Feb. 2013
  • Japan Renal Biopsy Registry and Japan Kidney Disease Registry: Committee Report for 2009 and 2010., (H.Sugiyama), H.Yokoyama, H.Sato, T.Saito, Y.Kohda, S.Nishi, K.Tsuruya, H.Kiyomoto, H.Iida, T.Sasaki, M.Higuchi, M.Hattori, K.Oka, S.Kagami, T.Kawamura, T.Takeda, H.Hataya, Y.Fukasawa, A.Fukatsu, K.Morozumi, N.Yoshikawa, A.Shimizu, H.Kitamura, Y.Yuzawa, S.Matsuo, Y.Kiyohara, K.Joh, M.Nagata, T.Taguchi, H.Makino, Clinical and experimental nephrology17:155-173Feb. 2013
  • Japan Diabetic Nephropathy Cohort Study: study design, methods, and implementation., (K.Furuichi), M.Shimizu, T.Toyama, D.Koya, Y.Koshino, H.Abe, K.Mori, H.Satoh, M.Imanishi, M.Iwano, H.Yamauchi, E.Kusano, S.Fujimoto, Y.Suzuki, S.Okuda, K.Kitagawa, Y.Iwata, S.Kaneko, S.Nishi, H.Yokoyama, Y.Ueda, M.Haneda, H.Makino, T.Wada, Clinical and experimental nephrology17:819-826Feb. 2013
  • The effects of continuing and discontinuing smoking on the development of chronic kidney disease (CKD) in the healthy middle-aged working population in Japan., Y.Noborisaka, M.Ishizaki, Y.Yamada, R.Honda, H.Yokoyama, M.Miyao, M.Tabata, Environmental Health and Preventive Medicine18:24-322013
  • Progressive multifocal leukoencephalopathy developed 26 years,after renal transplantation., S.Nagayama, Y.Gondo, S.Araya, N.Minato, M.Fujita, M.Kaito, M.Nakanishi, K.Tanaka, H.Yamaya, H.Yokoyama, K.Nakamichi, M.Saijo, K.Okamoto, Y.Toyoshima, A.Kakita, M.Matsui, Clinical neurology and neurosurgery115:1482-14842013
  • Nodular lesions and mesangiolysis in diabetic nephropathy., (T.Wada), M. Shimizu, H.Yokoyama, Y. Iwata, Y. Sakai, S. Kaneko, K. Furuichi, Clinical and experimental nephrology17:3-92013
  • Distribution of and factors contributing to chronic kidney disease in a middle-aged working population., Y.Noborisaka, M.Ishizaki, Y.Yamada, R.Honda, H.Yokoyama, M.Miyao, M.Tabata, Environmental Health and Preventive Medicine18:466-4762013
  • Renal disease in the elderly and the very elderly Japanese: analysis of the Japan Renal Biopsy Registry (J-RBR), H.Yokoyama, H.Sugiyama, H.Sato, T.Taguchi, M.Nagata, S.Matsuo, H.Makino, T.Watanabe, T.Saito, Y.Kiyohara, S.Nishi, H.Iida, K.Morozumi, A.Fukatsu, T.Sasaki, K.Tsuruya, Y.Kohda, M.Higuchi, H.Kiyomoto, S.Goto, M.Hattori, H.Hataya, S.Kagami, N.Yoshikawa, Y.Fukasawa, Y.Ueda, H.Kitamura, A.Shimizu, K.Oka, N.Nakagawa, T.Ito, S.Uchida, K.Furuichi, I.Nakaya, S.Umemura, K.Hiromura, M.Yoshimura, N.Hirawa, T.Shigematsu, M.Fukagawa, M.Hiramatsu,Y.Terada, O.Umemura, T.Kawata, A.Matsunaga, A.Kuroki, Y.Mori, K.Mitsuiki, H.Yoshida, Clinical and experimental nephrology16:903-920Oct. 2012
  • Circulating fibrocytes in ischemia-reperfusion injury and chronic renal allograft fibrosis, S.Kimura, M.Asaka, H.Atsumi, J.Imura, K.Fujimoto, Y.Chikazawa, M.Nakagawa, H.Okuyama, H.Yamaya, H.Yokoyama, Nephron. Clinical practice121:c16-c24Sep. 2012
  • Cytokine profiles of patients with enterohemorrhagic Escherichia coli O111-induced hemolytic-uremic syndrome, (M.Shimizu), M.Kuroda, N.Sakashita, M.Konishi, H.Kaneda, N.Igarashi, J.Yamahana, H.Taneichi, H.Kanegane, M.Ito, S.Saito, K.Ohta, T.Taniguchi, K.Furuichi, T.Wada, M.Nakagawa, H.Yokoyama, A.Yachie, Cytokine.60:694-700Aug. 2012
  • A case of chronic hepatitis C with nephrotic diabetic nephropathy who achieved sustained viral remission by double-filtration plasmapheresis and interferon combination therapy, H.Okuyama, S.Kimura, K.Fujimoto, J.Imura, Y.Chikazawa, M.Nakagawa, H.Yamaya, H.Yokoyama, Internal medicine (Tokyo, Japan)51:1991-1995Apr. 2012
  • Membranous nephropathy in Japan: analysis of the Japan Renal Biopsy Registry (J-RBR), H.Yokoyama, T.Taguchi, H.Sugiyama, H.Sato, Clinical and experimental nephrology16:557-563Feb. 2012
  • Elevated serum levels of interleukin-18 in patients with overt diabetic nephropathy: effects of miglitol, (T.Uzu), H.Yokoyama, H.Ito, D.Koya, A.Nakagawa, M.Nishizawa, H.Maegawa, Y.Yokomaku, S.Araki, A.Abiko, M.Haneda, Clinical and experimental nephrology15:58-63Dec. 2011
  • Matrix metalloproteinase-2 (MMP-2) and membrane-type 1 MMP (MT1-MMP) affect the remodeling of glomerulosclerosis in diabetic OLETF rats, (K.Furuichi), Y.Hisada, M.Shimizu, T.Okumura, K.Kitagawa, K.Yoshimoto, Y.Iwata, H.Yokoyama, S.Kaneko, T.Wada, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.26:3124-3131Mar. 2011
  • Japan renal biopsy registry: the first nationwide, web-based, and prospective registry system of renal biopsies in Japan, (H.Sugiyama), H.Yokoyama, H.Sato, T.Saito, Y.Kohda, S.Nishi, K.Tsuruya, H.Kiyomoto, H.Iida, T.Sasaki, M.Higuchi, M.Hattori, K.Oka, S.Kagami, M.Nagata, T.Kawamura, M.Honda, Y.Fukasawa, A.Fukatsu, K.Morozumi, N.Yoshikawa, Y.Yuzawa, S.Matsuo, Y.Kiyohara, K.Joh, T.Taguchi, H.Makino, Clinical and experimental nephrology15:493-503Mar. 2011
  • Clinicopathological insights into lupus glomerulonephritis in Japanese and Asians, H.Yokoyama, H.Okuyama, H.Yamaya, Clinical and experimental nephrology15:321-3302011
  • Cigarette smoking, proteinuria, and renal function in middle-aged Japanese men from an occupational population, Y.Noborisaka, M.Ishizaki, M.Nakata, Y.Yamada, R.Honda, H.Yokoyama, M.Miyao, M.Tabata, Environmental Health and Preventive Medicine17:147-1562011
  • Effectiveness of weekly percutaneous maxacalcitol injection therapy in patients with secondary hyperparathyroidism, A.Saito, Y.Matsumoto, Y.Oyama, M.Asaka, H.Yokoyama, Therapeutic Apheresis and Dialysis14(1):98?103Feb. 2010
  • A case of second renal transplantation with acute antibody-mediated rejection complicated with BK virus nephropathy, H.Atsumi, M.Asaka, S.Kimura, J.Imura, K.Fujimoto, Y.Chikazawa, M.Nakagawa, H.Okuyama, H.Yamaya, M.Moriyama, T.Tanaka, K.Suzuki, H.Yokoyama, Clinical transplantation24:35-38Feb. 2010
  • Long-term natural history of acquired cystic disease of the kidney, (I.Ishikawa), S.Hayama, K.Morita, T.Nakazawa, H.Yokoyama, R.Honda, K.Satoh, T.Kakuma, Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.14:409-4162010
  • Effectiveness of weekly percutaneous maxacalcitol injection therapy in patients with secondary hyperparathyroidism., A.Saito, Y.Matsumoto, Y.Oyama, M.Asaka, H.Yokoyama, Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.14:98-1032010
  • Revised equations for estimated GFR from serum creatinine in Japan, (S.Matsuo), E.Imai, M.Horio, Y.Yasuda, K.Tomita, K.Nitta, K.Yamagata, Y.Tomino, H.Yokoyama, A.Hishida, American journal of kidney diseases : the official journal of the National Kidney Foundation.53:982-992Jun. 2009
  • The relationship between initial diagnosis and long-term prognosis in lupus nephritis, H.Okuyama, S.Kimura, H.Atsumi, J.Imura, K.Fujimoto, Y.Chikazawa, M.Nakagawa, H.Imamura, H.Yamaya, M.Asaka, N.Tomosugi, H.Yokoyama51:44-50Jan. 2009
  • Prophylactic continuous hemodialysis after coronary angiography in patients wit renal insufficiency, (K.Sato), M.Asaka, M.Nakagawa, H.Imamura, H.Yokoyama, I.Ishikawa42:237-2432009
  • Prevalence of chronic kidney disease in the Japanese general poulation, (E.Imai), M.Horio, T.Watanabe, K.Iseki, K.Yamagata, S.Hara, N.Ura, Y.Kiyohara, T.Moriyama, Y.Ando, S.Fujimoto, T.Konta, H.Yokoyama, H.Makino, A.Hishida, S.Matsuo, Clinical and experimental nephrology13:621-6302009
  • Urinalysis in chronic kidney diseases, H.Yokoyama, H.Yamaya66:1713-1718Sep. 2008
  • A case report of an adult with severe hyperlipidemia during acute lymphocytic leukemia induction therapy successfully treated with plasmapheresis, M.Nakagawa, S.Kimura, K.Fujimoto, H.Atsumi, J.Imura, Y.Chikazawa, H.Imamura, H.Okuyama, H.Yamaya, T.Fukushima, A.Nakagawa, M.Asaka, H.Yokoyama, Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.12:509-513Jan. 2008
  • Ischemia-reperfusion injury as the leading cause of primary non-function in renal transplantation using donors with prolonged warm ischemic time, M.Asaka, H.Imamura, K.Sato, H.Atsumi, H.Okuyama, H.Yamaya, H.Yokoyama, I.Ishikawa, Clinical transplantation22(Suppl 19):19-242008
  • Biocompatibility and permeability of dialyzer membranes do not affect anemia, erythropoietin dosage or mortality in Japanese patients on chronic non-reuse hemodialysis:a prospective cohort study from the J-DOPPS II study, H.Yokoyama, T.Kawaguchi, T.Wada, Y.Takahashi, T.Higashi, S.Yamazaki, S.Fukuhara, T.Akiba, T.Akizawa, Y.Asano, K.Kurokawa, A.Saito, Nephron. Clinical practice109:c100-c1082008
  • Blockade of IP-10/CXCR3 promotes progressive renal fibrosis, (I.Nakaya), T.Wada, K.Furuichi, N.Sakai, K.Kitagawa, H.Yokoyama, Y.Ishida, T.Kondo, T.Sugaya, H.Kawachi, F.Shimizu, S.Narumi, M.Haino, C.Gerard, K.Matsushima, S.Kaneko, Nephron. Experimental nephrology107:e12-e21Jul. 2007
  • Advances in apheresis therapy for glomerular diseases, H.Yokoyama, T.Wada, W.Zhang, H.Yamaya, M.Asaka, Clinical and experimental nephrology11:122-127Jan. 2007
  • Effect of sevelamer hydrochloride on markers of bone turnover in Japanese dialysis patients with low biointact PTH levels, (Y.Iwata), T.Wada, H.Yokoyama, T,Toyama, S.Kitajima, T.Okumura, A.Hara, J.Yamahana, I.Nakaya, M.Kobayashi, K.Kitagawa, S.Kokubo, K.Yoshimoto, K.Shimizu, N.Sakai, K.Furuichi, Y.Koshino, S.Takeda, K.Takasawa, S.Ohta, M.Takaeda, C.Takaeda, S.Kaneko, Internal medicine (Tokyo, Japan)447-4522007
  • Rituximab therapy for epstein-barr virus-related chronic hepatitis following living donor kidney transplantation, (K.Ohta), M.Shimizu, A.Nakai, T.Toma, Y.Kasahara, C.Arii, A.Yachie, T.Kawamura, A.Aikawa, A.Hasegawa, K.Sato, H.Yokoyama, I.Ishikawa, S.Koizumi, American journal of kidney diseases : the official journal of the National Kidney Foundation.48:986-989Dec. 2006
  • Secondary lymphoid tissus chemokine (SLC/CCL21)/CCR7 signaling regulates fibrocytes in renal fibrosis, (N.Sakai), T.Wada, H.Yokoyama, M.Lipp, S.Ueha, K.Matsushima, S.Kaneko, Proceedings of the National Academy of Sciences of the United States of America103:14098-14103Sep. 2006
  • TAK-603, an anti-inflammatory compound, reduces crescentic glomerulonephritis and preserves renal function in WKY rats, (J.Yamahana), T.Wada, K.Furuichi, N.Sakai, H.Yokoyama, S.Kaneko, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.21:2736-2744Aug. 2006
  • Remission of IgA nephropathy after allogeneic peripheral blood stem cell transplantation followed by immunosuppression for acute lymphocytic leukemia, (Y.Iwata), T.Wada, A.Uchiyama, A.Miwa, I.Nakaya, T.Tohyama, Y.Yamada, T.Kurokawa, T.Yoshida, S.Ohta, H.Yokoyama, H.Iida, Internal medicine (Tokyo, Japan)45:1291-1295Aug. 2006
  • Proteomic analysis of serum, outflow dialysate and adsorbed protein onto dialysis membranes (polysulfone and PMMA) during hemodialysis treatment using SELDI-TOF-MS, I.Ishikawa, Y.Chikazawa, K.Sato, M.Nakagawa, H.Imamura, S.Hayama, H.Yamaya, M.Asaka, N.Tomosugi, H.Yokoyama, K.Matsumoto, American journal of nephrology26:372-380Jun. 2006
  • Reduction in chronic allograft nephropathy by inhibition of p38 mitogen-activated protein kinase, (T.Wada), H.Azuma, K.Furuichi, N.Sakai, K.Kitagawa, Y.Iwata, K.Matsushima, S.Takahara, H.Yokoyama, S.Kaneko, American journal of nephrology26:319-3252006
  • The outcome and a new ISN/RPS 2003 classification of lupus nephritis in Japanese., Kidney international.66:2382-2388Dec. 2004
  • Immunomodulation effects and clinical evidence of apheresis in renal diseases., Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.7:513-519Dec. 2003
  • Chemokines in renal fibrosis and glomerulosclerosis., Current Med Literature Nephrology and Hypertension9(4):89-96Nov. 2003


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