HATANO Eiju

■FacultyDepartment of Orthopaedic Surgery
■PositionAssociate Professor

Researcher Profile & Settings

Research

    Overview of research:
    It has been reported that apoptosis of vertebral disc cells occurs in the degenerative intervertebral disc. However, its molecular mechanism remains to be defined. The gene expression of Bax and Bcl-2 was analyzed in degenerative intervertebral disc. As a result, mechanical stress of the disc induces apoptosis through a Bax, reducing the number of cells and the synthesis of extracelular matrix proteins and resulting in the degeneration of the disc. On the other hand, a feedback mechanism appears to be activated by an increase of Bcl-2 gene expression to repress apoptosis induction.

Special Field

  • Orthopaedic surgery

Education

  • Kanazawa Medical University Graduate School Division of Medicine

Degree

  • Ph.D in Medicine

Association Memberships

  • 2000Japanese Orthopaedic Association
  • 2001The Central Japan Association of Orthopaedic Surgery and Traumatology
  • 2002The Japanese Society for Spine Surgery and Related Research

Academic & Professional Experience

  • Apr. 2006Kanazawa Medical University Assistant Professor

Research Activities

Published Papers

  • Microscopic bilateral fenestration via a unilateral approach for lumbar spinal canal stenosis, (T.Fujita), T.Okuda, H.Hosokawa, E.Hatano, Y.Yasuda, N.Kawahara, T.Matsumoto, Journal of Spine Research, 2:1372-1376, Aug. 2011
  • Perioperative complications of spine surgery for lumbar canal stenosis in elderly patients, Y.Yasuda, T.Fujita, E.Hatano, T.Okuda, H.Hosokawa, T.Matsumoto, Journal of Spine Research, 2:372-375, Feb. 2011
  • Incidence of spondylolysis, spondylolisthesis and degenerative scoliosis of the lumbar spine in patients with terminal stage hip osteoarthritis, T.Okuda, T.Fujita, A.Kaneuji, E.Hatano, T.Ichiseki, Y.Yasuda, K.Fukui, T.Matsumoto, Journal of Spine Research, 1:1964-1967, Nov. 2010
  • Clinical outcome of posterior cervical decompression using a tubular retractor for cervical radiculopathy with a minimum follow-up of 2 years, T.Fujita, T.Okuda, H.Hosokawa, E.Hatano, Y.Yasuda, T.Matsumoto, Journal of Spine Research, 1:1507-1511, Aug. 2010
  • Clinical results of the displased intra-articular calcaneal fractures treated by open reduction and internal fixation, M.Okada, E.Hatano, K.Hiromura, H.Maeoka, T.Matsumoto, 31:117-121, May 2010
  • Clinical results of computer navigation-assisted minimally invasive TLIF (MIS-TLIF), T.Fujita, T.Okuda, E.Hatano, Y.Yasuda, T.Matsumoto, 9:75-78, Aug. 2007
  • Minimally invasive TLIF (MIF-TLIF) via a unilateral approach, T.Fujita, T.Okuda, H.Hosokawa, E.Hatano, Y.Yasuda, T.Matsumoto, 18:665-668, Apr. 2007
  • Posterior cervical herniotomy using METRx Micro Discectomy system for cervical disc herniation, T.Fujita, T.Okuda, E.Hatano, Y.Yasuda, T.Matsumoto, 8:75-78, Aug. 2006
  • Expression of ADAMTS-4 (aggrecanase-1) and possible involvement in regression of lumbar disc herniation, E.Hatano, T.Fujita, Y.Ueda, T.Okuda, S.Katsuda, Y.Okada, T.Matsumoto, Spine, 31:1426-1432, Jun. 2006