TANIDA Mamoru

■FacultyDepartment of Physiology Ⅱ
■PositionAssociate Professor

Researcher Profile & Settings

Degree

  • Ph.D in Medicine

Research Activities

Published Papers

  • Electrophysiological Mechanism Underlying Vagal Nerve Activity in Mice, Mamoru Tanida, Brain and Nerve, 74:959-964, Aug. 2022
  • Central mechanism of autonomic actions induced by leptin and peripheral organs-brain crosstalk, Tanida Mamoru, The Autonomic Nervous System, 58:237-240, 2021
  • Angiopoietin-2 is released during anaphylactic hypotension in anesthetized and unanesthetized rats, Tao Zhang, Toshishige Shibamoto, Mamoru Tanida, Makoto Taniguchi,Yuhichi Kuda, Wei Yang, Yasutaka Kurata, PLOS ONE, 15:e0242026, Nov. 2020
  • The liver-brain-gut neural arc maintains the Treg cell niche in the gut, (Teratani Toshiaki), Mikami Yohei, Nakamoto Nobuhiro, Suzuki Takahiro, Harada Yosuke, Okabayashi Koji, Hagihara Yuya, Taniki Nobuhito, Kohno Keita, Shibata Shinsuke, Miyamoto Kentaro, Ishigame Harumichi, Chu Po-Sung, Sujino Tomohisa, Suda Wataru, Hattori Masahira, Matsui Minoru, Okada Takaharu, Okano Hideyuki, Inoue Masayuki, Yada Toshihiko, Kitagawa Yuko, Yoshimura Akihiko, Tanida Mamoru, Tsuda Makoto, Iwasaki Yusaku, Kanai Takanori, Nature, 585:591-596, Sep. 2020
  • Multiple Dynamical Mechanisms of Phase-2 Early Afterdepolarizations in a Human Ventricular Myocyte Model: Involvement of Spontaneous SR Ca2+ Release, Yasutaka Kurata, Kunichika Tsumoto, Kenshi Hayashi, Ichiro Hisatome, Yuhichi Kuda, Mamoru Tanida, Frontiers in Physiology, 10:1545, Jan. 2020
  • Anaphylaxis stimulates afferent vagal nerve activity and efferent sympathetic nerve activity in the stomach of anesthetized rats, Kuda Y, Tanida M, Chen F, Kurata Y, Shibamoto T, AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSI, 317:R337-R345, Aug. 2019
  • Central Injection of Leptin Increases Sympathetic Nerve Outflows to the Stomach and Spleen in Anesthetized Rats, Tanida M, Iwasaki Y, Yamamoto N, In Vivo, 33:1827-1832, 2019
  • Tonic contraction develops in the colon during anaphylactic hypotension in anesthetized rats, Tao Zhang, Toshishige Shibamoto, Mamoru Tanida, Yuhichi Kuda, Wei Yang, Yasutaka Kurata, Journal of Physiological Sciences, 69:953-960, 2019
  • Renal response to anaphylaxis in anesthetized rats and isolated perfused rat kidneys: roles of nitric oxide., Mukai K, Kuda Y, Shibamoto T, Tanida M, Kurata Y, Yokoyama H., The Journal of Physiological Sciences, 68:689-697, Sep. 2018
  • Pretreatment with an angiotensin II receptor blocker abolished ameliorating actions of adipose-derived stem cell sheets on cardiac dysfunction and remodeling after myocardial infarction., Yamamoto K, Kurata Y, Inoue Y, Adachi M, Tsuneto M, Miake J, Ogino K, Ninomiya H, Yoshida A, Shirayoshi Y, Suyama Y, Yagi S, Nishimura M, Yamamoto K, Hisatome I., Regenerative Therapy, 9:79-88, Sep. 2018
  • Anaphylactic hypotension causes renal and adrenal sympathoexcitaion and induces c-fos in the hypothalamus and medulla oblongata, Tanida M, Zhang T, Sun L, Song J, Yang W, Kuda Y, Kurata Y, Shibamoto T., EXPERIMENTAL PHYSIOLOGY, 103:790-806, Jun. 2018
  • Gastric vascular and motor responses to anaphylactic hypotension in anesthetized rats, in comparison to those with hemorrhagic or vasodilator-induced hypotension, Kuda Y, Shibamoto T, Zhang T, Yang W, Tanida M, Kurata Y, Journal of Physiological Sciences, 68:253-260, May 2018
  • Protective effects of topiroxostat on an ischemia-reperfusion model of rat hearts., Tanno S, Yamamoto K, Kurata Y, Adachi M, Inoue Y, Otani N, Mishima M, Yamamoto Y, Kuwabara M, Ogino K, Miake J, Ninomiya H, Shirayoshi Y, Okada F, Yamamoto K, Hisatome I., CIRCULATION JOURNAL, 82:1101-1111, Mar. 2018
  • Restoration of mutant hERG stability by inhibition of HDAC6., Li P, Kurata Y, Endang M, Ninomiya H, Higaki K, Taufiq F, Morikawa K, Shirayoshi Y, Horie M, Hisatome I., J Mol Cell Cardiol., 115:158-169, Feb. 2018
  • β2-adrenoceptor blockade deteriorates systemic anaphylaxis by enhancing hyperpermeability in anesthetized mice, Yang W, Shibamoto T, Kuda Y, Zhang T, Tanida M, Kurata Y., Allergy Asthma & Immunology Research, 10:52-61, Jan. 2018
  • Mouse Anaphylactic Hypotension Is Characterized by Initial Baroreflex Independent Renal Sympathoinhibition Followed by Sustained Renal Sympathoexcitation., Zhang T, Tanida M, Uchida K, Suzuki Y, Yang W, Kuda Y, Kurata Y, Tominaga M, Shibamoto T., frontiers in Physiology, 8:669, 2017
  • Biphasic Renal Sympathetic Response to Hemorrhagic Hypotension in Mice., Zhang T, Tanida M, Uchida K, Suzuki Y, Yang W, Kuda Y, Kurata Y, Tominaga M, Shibamoto T., Shock, 48:576-582, 2017
  • Blockade of β2-adrenoceptor, rather than β1-adrenoceptor, deteriorates cardiac anaphylaxis in isolated blood-perfused rat hearts., Kuda Y, Shibamoto T, Yang W, Zhang T, Tanida M, Kurata Y., Cardiol J, 24:403-408, 2017
  • Dynamical mechanisms of phase-2 early afterdepolarizations in human ventricular myocytes: insights from bifurcation analyses of two mathematical models., Kurata Y, Tsumoto K, Hayashi K, Hisatome I, Tanida M, Kuda Y, Shibamoto T., Am J Physiol Heart Circ Physiol, 312:H106-H127, 2017
  • l-Ornithine stimulates growth hormone release in a manner dependent on the ghrelin system., Ho YY, Nakato J, Mizushige T, Kanamoto R, Tanida M, Akiduki S, Ohinata K., Food Funct., 8:2110-2114, 2017
  • Epigallocatechin gallate induces extracellular degradation of amyloid β-protein by increasing neprilysin secretion from astrocytes through activation of ERK and PI3K pathways., (Yamamoto N), Shibata M, Ishikuro R, Tanida M, Taniguchi Y, Ikeda-Matsuo Y, Sobue K., Neuroscience., 362:70-78, 2017
  • L-Ornithine intake affects sympathetic nerve outflows and reduces body weight and food intake in rats., (Y.Konishi), Y.Koosaka, R.Maruyama, K.Imanishi, K.Kasahara, A.Matsuda, S.Akiduki, Y.Hishida, Y.Kurata, T.Shibamoto, J.Satomi, M.Tanida, Brain Research Bulletin, 111:48-52, 2015
  • Systemic vasoconstriction modulates the responses of pulmonary vasculature and airway to vasoconstrictors in anesthetized rats. , M.Wang, T.Shibamoto, Y.Kuda, M.Tanida, Y.Kurata, Experimental Lung Research, 41:324-334, 2015
  • Pulmonary vascular and airway responses to systemic vasoconstrictors in anesthetized BALB/c mice. , M.Wang, T.Shibamoto, S.Shinomiya, Y.Yamamoto, Y.Kurata, Y.Kuda, M.Tanida, H.Toga, Journal of cardiovascular pharmacology, 65:325-334, 2015
  • Possible role of afferent autonomic signals in abdominal organs in anorexic and cardiovascular responses to nicotine injection in rats., (S.Yagi), M.Tanida, J.Satomi, NeuroReport, 26:445-449, 2015
  • Leptin receptor signaling in the hypothalamus regulates hepatic autonomic nerve activity via phosphatidylinositol 3-kinase and AMP-activated protein kinase., M.Tanida, N.Yamamoto, DA.Morgan, Y.Kurata, T.Shibamoto, K.Rahmouni, The Journal of Neuroscience, 35:474-484, 2015
  • Hypothalamic nesfatin-1 stimulates sympathetic nerve activity via hypothalamic ERK signaling., M.Tanida, H.Gotoh, N.Yamamoto, M.Wang, Y.Kuda, Y.Kurata, M.Mori, T.Shibamoto, Diabetes, 64:3725-3736, 2015
  • Exercise attenuates ischemia-reperfusion injury of nonalcoholic fatty liver of OLETF rat. , T.Shibamoto, Y.Kuda, M.Tanida, M.Wang, Y.Kurata, Journal of Gastroenterology, Pancreatology & Liver Disorders, 2:1-6, 2015
  • Carnosine and the control of blood glucose, N.Okumura, M.Tanida, A.Niijima, N.Tsuruoka, Y.Kiso, Y.Horii, K.Nagai, Food and Nutritional Components in Focus, 8:257-276, 2015
  • Soy isoflavone affects the autonomic nervous system in a tissue-specific manner in anesthetized rats, M.Tanida, K.Imanishi, M.Komatsu, J.Satomi, N.Yamamoto, M.Wang, Y.Kurata, T.Shibamoto, Experimental biology and medicine (Maywood, N.J.), 239:477?483, 2014
  • Olfactory stimulatory with grapefruit and lavender oils change autonomic nerve activity and physiological function., (K.Nagai), A.Niijima, Y.Horii, J.Shen, M.Tanida, Autonomic neuroscience : basic & clinical., 185:29-35, 2014
  • Mouse anaphylactic shock is caused by reduced cardiac output, but not by systemic vasodilatation or pulmonary vasoconstriction, via PAF and histamine., M.Wang, T.Shibamoto, M.Tanida, Y.Kuda, Y.Kurata, Life sciences., 116:98-105, 2014
  • Major contribution of vasospasm-induced coronary blood flow reduction to anaphylactic ventricular dysfunction assessed in isolated blood-perfused rat heart, Y.Kuda, Y.Kurata, M.Wang, M.Tanida, T.Shibamoto, Cardiology journal., 21:11-17, 2014
  • Leptin inhibits amyloid β-protein fibrillogenesis by decreasing GM1 gangliosides on the neuronal cell surface through PI3K/Akt/mTOR pathway., (N.Yamamoto), M.Tanida, R.Kasahara, K.Sobue, K.Suzuki, Journal of neurochemistry, 131:323-332, 2014
  • Leptin inhibits amyloid β-protein degradation through decrease of neprilysin expression in primary cultured astrocytes., (N.Yamamoto,), M.Tanida, Y.Ono, R.Kasahara, Y.Fujii, K.Ohora, K.Suzuki, K.Sobue, Biochemical and biophysical research communications, 445:214-217, 2014
  • Injection of Lactobacillus casei strain Shirota affects autonomic nerve activities in a tissue-specific manner, and regulates glucose and lipid metabolism in rats., M.Tanida, K.Imanishi, H.Akashi, Y.Kurata, O.Chonan, E. Naito, S.Kunihiro, M.Kawai, A.Kato-Kataoka, T.Shibamoto, Journal of diabetes investigation, 5:153-161, 2014
  • Effects of anesthetics on the renal sympathetic response to anaphylactic hypotension in rats., L.Sun, M.Tanida, M.Wang, Y.Kuda, Y.Kurata, T.Shibamoto, PloS one, 9:e113945;1-15, 2014
  • Angiotensin II and vasopressin are involved in the defense system against anaphylactic hypotension in anesthetized rats., M.Wang, T.Shibamoto, Y.Kuda, L.Sun, M.Tanida, Y.Kurata., European journal of pharmacology., 731:38-43, 2014
  • MRI Reveals edema in larynx (But not in brain) during anaphylactic hypotension in anesthetized rats., I.Toyota, M.Tanida, T.Shibamoto, Mofei Wang, Y.Kurata, H.Tonami, Allergy, asthma & immunology research., 5:389-396, Nov. 2013
  • Effect of hyperpolarization-activated current I(f) on robustness of sinoatrial node pacemaking: theoretical study on influence of intracellular Na(+) concentration., Y.Kurata, I.Hisatome, M.Tanida, T.Shibamoto, American journal of physiology. Heart and circulatory physiology., 304:H1337-H1351, Mar. 2013
  • Nitric oxide and β2-adrenoceptor activation attenuate pulmonary vasoconstriction during anaphylactic hypotension in anesthetized BALB/c mice., S.Shinomiya, T.Shibamoto, Y.Kurata, Y.Kuda, W..Zhang, M.Tanida, H.Toga, Experimental lung research., 39:119-129, Jan. 2013
  • Rat hepatic and splanchnic vascular responses to anaphylactic shock, compared with hemorrhagic or vasodilator-induced shock., W.Zhang, T.Shibamoto, M.Tanida, M.Wang, L.Sun, Y.Kurata, In vivo (Athens, Greece), 27:485-494, 2013
  • Central PACAP mediates the sympathetic effects of leptin in a tissue-specific manner., M.Tanida, A.Hayata, N.Shintani, N.Yamamoto, Y.Kurata, T.Shibamoto, D.A.Morgan, Rahmouni K, H.Hashimoto, Neuroscience., 238:297-304., 2013
  • Repeated activation of C1 neurons in medulla oblongata decreases anti-inflammatory effect via the hypofunction of the adrenal gland adrenergic response, Chikara Abe, Chikako Katayama, Murat Bazek, Yasuna Nakamura, Kento Ohbayashi, Kazuhiro Horii, Chisato Fujimoto, Mamoru Tanida, Yusaku Iwasaki, Tsuyoshi Inoue, Fumiaki Nin, Hironobu Morita, 111:138-150, Jul. 2023
  • Hepatic glycogenolysis and hypometabolism induced by chemogenetic stimulation of C1 neurons, Chikara Abe, Chikako Katayama, Murat Bazek, Kento Ohbayashi, Kazuhiro Horii, Mamoru Tanida, Fumiaki Nin, Yusaku Iwasaki, The Journal of Physiology, 601:2293-2306, Jun. 2023
  • Mechanisms for hypothermia during anaphylactic hypotension in awake rats, Toshishige Shibamoto, Munenori Ono, Mamoru Tanida, Yuhichi Kuda, Yasutaka Kurata , American journal of physiology. Regulatory, integrative and comparative physiology, 325:R446-R455, Nov. 2023
  • Theoretical prediction of early afterdepolarization-evoked triggered activity formation initiating ventricular reentrant arrhythmias, Kunichika Tsumoto, Takao Shimamoto, Yuma Aoji, Yukiko Himeno, Yuhichi Kuda, Mamoru Tanida, Akira Amano, Yasutaka Kurata, Computer Methods and Programs in Biomedicine, 240:107722, Oct. 2023
  • Roles of vasopressin in renal blood flow and vascular resistance in male mice after treadmill running: A mechanism for ALPE, Kazutoshi Nomura, Mamoru Tanida, Ryoko Akai, Tomohisa Yabe, Ai Fujii, Kanae Nomura, Keiichiro Okada, Kazuaki Okino, Norifumi Hayashi, Keiji Fujimoto, Yasutaka Kurata, Takao Iwawaki, Kengo Furuichi, Physiological Reports, 13:e70648, Dec. 2025
  • Chained occurrences of early afterdepolarizations may create a directional triggered activity to initiate reentrant ventricular tachyarrhythmias, Kunichika Tsumoto, Takao Shimamoto, Yuma Aoji, Yukiko Himeno, Yuhichi Kuda, Mamoru Tanida, Akira Amano, Yasutaka Kurata, Volume 261:0169-2607, Apr. 2025
  • Functional identification of vagal afferent branch from the gastrointestinal organs by capsaicin administration in mice, Mamoru Tanida, Yusaku Iwasaki, Yoshinori Okamoto, Yuhichi Kuda, Kunichika Tsumoto, Hideto Jinno, Yasutaka Kurata, Volume 329:Issue 6:R972-R986, Dec. 2025