SHIBAMOTO Toshishige

FacultyDepartment of Physiology Ⅱ
PositionProfessor

Researcher Profile & Settings

Research

    Overview of research:
    Circulatory Physiology

Special Field

  • Physiology in General
  • Anesthesiology and Rescue Medicine

Education

  • Shinshu University Faculty of Medicine

Degree

  • Ph.D in Medicine

Academic & Professional Experience

  • 19851986Shinshu University School of Medicine, Depart of Anatomy Instructor
  • 19871989University of South Alabama, Department of Physiology Research Associate
  • 19881990Shinshu University School of Medicine Instructor
  • 19901992Shinshu University School of Medicine Assistant Professor
  • 19922001Shinshu University School of Medicine Associate Professor

Research Activities

Published Papers

  • l-Ornithine intake affects sympathetic nerve outflows and reduces body weight and food intake in rats. , (Y.Konishi), Y.Koosaka, R.Maruyama, K.Imanishi, K.Kasahara, A.Matsuda, S.Akiduki, Y.Hishida, Y.Kurata, T.Shibamoto, J.Satomi, M.Tanida, Brain Research Bulletin111:48-522015
  • The effect of tolvaptan, a vasopressin V2 receptor antagonist, on the portal venous pressure in rats., T.Shibamoto, M.Wang , Japanese Pharmacology & Therapeutics 43:1283-12942015
  • Systemic vasoconstriction modulates the responses of pulmonary vasculature and airway to vasoconstrictors in anesthetized rats. , M.Wang, T.Shibamoto, Y.Kuda, M.Tanida, Y.Kurata, Experimental Lung Research41:324-3342015
  • Pulmonary vascular and airway responses to systemic vasoconstrictors in anesthetized BALB/c mice. , M.Wang, T.Shibamoto, S.Shinomiya, Y.Yamamoto, Y.Kurata, Y.Kuda, M.Tanida, H.Toga, Journal of cardiovascular pharmacology65:325-3342015
  • Leptin receptor signaling in the hypothalamus regulates hepatic autonomic nerve activity via phosphatidylinositol 3-kinase and AMP-activated protein kinase., M.Tanida, N.Yamamoto, DA.Morgan, Y.Kurata, T.Shibamoto, K.Rahmouni, The Journal of Neuroscience35:474-4842015
  • Hypothalamic nesfatin-1 stimulates sympathetic nerve activity via hypothalamic ERK signaling. , M.Tanida, H.Gotoh, N.Yamamoto, M.Wang, Y.Kuda, Y.Kurata, M.Mori, T.Shibamoto, Diabetes64:3725-37362015
  • Exercise attenuates ischemia-reperfusion injury of nonalcoholic fatty liver of OLETF rat. , T.Shibamoto, Y.Kuda, M.Tanida, M.Wang, Y.Kurata, Journal of Gastroenterology, Pancreatology & Liver Disorders2:1-62015
  • Soy isoflavone affects the autonomic nervous system in a tissue-specific manner in anesthetized rats, M.Tanida, K.Imanishi, M.Komatsu, J.Satomi, N.Yamamoto, M.Wang, Y.Kurata, T.Shibamoto, Experimental biology and medicine (Maywood, N.J.)239:477?4832014
  • Mouse anaphylactic shock is caused by reduced cardiac output, but not by systemic vasodilatation or pulmonary vasoconstriction, via PAF and histamine., M.Wang, T.Shibamoto, M.Tanida, Y.Kuda, Y.Kurata, Life sciences.116:98-1052014
  • Major contribution of vasospasm-induced coronary blood flow reduction to anaphylactic ventricular dysfunction assessed in isolated blood-perfused rat heart, Y.Kuda, Y.Kurata, M.Wang, M.Tanida, T.Shibamoto, Cardiology journal.21:11-172014
  • Injection of Lactobacillus casei strain Shirota affects autonomic nerve activities in a tissue-specific manner, and regulates glucose and lipid metabolism in rats., M.Tanida, K.Imanishi, H.Akashi, Y.Kurata, O.Chonan, E. Naito, S.Kunihiro, M.Kawai, A.Kato-Kataoka, T.Shibamoto, Journal of diabetes investigation5:153-1612014
  • Effects of anesthetics on the renal sympathetic response to anaphylactic hypotension in rats., L.Sun, M.Tanida, M.Wang, Y.Kuda, Y.Kurata, T.Shibamoto, PloS one9:e113945;1-152014
  • Angiotensin II and vasopressin are involved in the defense system against anaphylactic hypotension in anesthetized rats., M.Wang, T.Shibamoto, Y.Kuda, L.Sun, M.Tanida, Y.Kurata., European journal of pharmacology.731:38-432014
  • MRI Reveals edema in larynx (But not in brain) during anaphylactic hypotension in anesthetized rats., I.Toyota, M.Tanida, T.Shibamoto, Mofei Wang, Y.Kurata, H.Tonami, Allergy, asthma & immunology research.5:389-396Nov. 2013
  • Alpha-adrenoceptor antagonists and chemical sympathectomy exacerbate anaphylaxis-induced hypotension, but not portal hypertension, in anesthetized rats., M.Wang, M.Tanida, T.Shibamoto, Y.Kurata, American journal of physiology. Regulatory, integrative and comparative physiology.305:R900-:R907Aug. 2013
  • Portal venular constriction during anaphylactic shock in anesthetized rats., M.Kitadate, T.Shibamoto, M.Tsutsumi, H.Tonami, Biomedical research (Tokyo, Japan)34:61-68Apr. 2013
  • Effect of hyperpolarization-activated current I(f) on robustness of sinoatrial node pacemaking: theoretical study on influence of intracellular Na(+) concentration., Y.Kurata, I.Hisatome, M.Tanida, T.Shibamoto, American journal of physiology. Heart and circulatory physiology.304:H1337-H1351Mar. 2013
  • Involvement of hypothalamic AMP-activated protein kinase in leptin-induced sympathetic nerve activation., M.Tanida, N.Yamamoto, T.Shibamoto, K.Rahmouni, PloS one8:e56660;1-11Feb. 2013
  • Nitric oxide and β2-adrenoceptor activation attenuate pulmonary vasoconstriction during anaphylactic hypotension in anesthetized BALB/c mice., S.Shinomiya, T.Shibamoto, Y.Kurata, Y.Kuda, W..Zhang, M.Tanida, H.Toga, Experimental lung research.39:119-129Jan. 2013
  • Rat hepatic and splanchnic vascular responses to anaphylactic shock, compared with hemorrhagic or vasodilator-induced shock., W.Zhang, T.Shibamoto, M.Tanida, M.Wang, L.Sun, Y.Kurata, In vivo (Athens, Greece)27:485-4942013
  • Central PACAP mediates the sympathetic effects of leptin in a tissue-specific manner., M.Tanida, A.Hayata, N.Shintani, N.Yamamoto, Y.Kurata, T.Shibamoto, D.A.Morgan, Rahmouni K, H.Hashimoto, Neuroscience.238:297-304.2013
  • Mast cells are not involved in the ischemia-reperfusion injury in perfused rat liver, T.Shibamoto, M.Tsutsumi, Y.Kuda, C.Ohmukai, W.Zhang, Y.Kurata, The Journal of surgical research174:114-119May 2012
  • Vascular perfusion limits mesenteric lymph flow during anaphylactic hypotension in rats, W.Zhang, T.Shibamoto, Y.Kuda, Y.Kurata, S.Shinomiya, H.Kida, H.Tsuchida, American journal of physiology. Regulatory, integrative and comparative physiology.302:R1191-R11962012
  • The responses of the hepatic and splanchnic vascular beds to vasopressin in rats, W.Zhang, T.Shibamoto, Y.Kuda, S.Shinomiya, Y.Kurata, Biomedical research (Tokyo, Japan)33:83-882012
  • Roles of sarcoplasmic reticulum Ca2+ cycling and Na+/Ca2+ exchanger in sinoatrial node pacemaking: insights from bifurcation analysis of mathematical models, Y.Kurata, I.Hisatome, T.Shibamoto, American journal of physiology. Heart and circulatory physiology.302:H2285-H23002012
  • Pulmonary vasoconstrictive and bronchoconstrictive responses to anaphylaxis are weakened via β2-adrenoceptor activation by endogenous epinephrine in anesthetized rats, W.Zhang, T.Shibamoto, Y.Kuda, C.Omukai, Y.Kurata, Anesthesiology.114:614-6232011
  • Portacaval shunting attenuates portal hypertension and systemic hypotension in rat anaphylactic shock, C.Kamikado, T.Shibamoto, W.Zhang, Y.Kuda, C.Omukai, Y.Kurata, The journal of physiological sciences : JPS61:161-1662011
  • Effects of β-adrenoceptor antagonists on anaphylactic hypotension in conscious, W.Zhang, T.Shibamoto, Y.Kurata, H.Kohno, European journal of pharmacology.650:303-3082011
  • Roles of hyperpolarization-activated current If in sinoatrial node pacemaking: insights from bifurcation analysis of mathematical models., Y.Kurata, H.Matsuda, I.Hisatome, T.Shibamoto, American journal of physiology. Heart and circulatory physiology.298:H1748-H17602010
  • Liver volume, as assessed by four ultrasonic crystals arranged to form a tetrahedron, decreases during anaphylactic shock in anesthetized rats., H.Takano, T.Shibamoto, W.Zhang, Y.Kurata, Shock (Augusta, Ga.)34:586-5912010
  • Exercise training attenuates anaphylactic venoconstriction in rat perfused liver, but does not affect anaphylactic hypotension in conscious rats., S.Cui, T.Shibamoto, W.Zhang, Y.Kurata, O.Kashimura, S.Miyamae, Clinical and experimental pharmacology & physiology.37:889-8932010
  • Mouse hepatic portal venoconstrictive response to vasoconstrictors is much weaker than that in rat, ZS.Zhao, T.Shibamoto, M.Tsutsumi, S.Cui, WM.Zhang, H.Takano, Y.Kurata, Journal of cardiovascular pharmacology.54:421-4262009
  • Hepatic microvascular pressure during anaphylactic shock in anesthetized rats, H.Takano, T.Shibamoto, W.Zhang, Y.Kurata, H.Toga, Microvascular research78:169-1732009
  • 7-nitroindazole, but not L-name or aminoguanidine, attenuates anaphylactic hypotension in conscious rats, W.Zhang, T.Shibamoto, S.Cui, H.Takano, Y.Kurata, Shock (Augusta, Ga.)31:201-2062009
  • Regional difference in dynamical property of sinoatrial node pacemaking: role of Na+ channel current., Y.Kurata, H.Matsuda, I.Hisatome, T.Shibamoto95:951-9772008
  • PAF, rather than histamine, participates in mouse anaphylactic hypotension., T.Shibamoto, W.Liu, S.Cui, W.Zhang, H.Takano, Y.Kurata, Pharmacology.82:114-1202008
  • Increased sinusoidal resistance is responsible for the basal state and endothelin-induced venoconstriction in perfused cirrhotic rat liver, T.Shibamoto, C.Kamikado, S.Koyama, Pflugers Archiv : European journal of physiology.456:467-4772008
  • Effects of pacemaker currents on creation and modulation of human ventricular pacemaker: theoretical study with application to biological pacemaker engineering, Y.Kurata, H.Matsuda, I.Hisatome, T.Shibamoto, American journal of physiology. Heart and circulatory physiology.292:H701-718Jan. 2007
  • Effects of pacemaker currents on creation and modulation of human ventricular pacemaker: theoretical study with application to biological pacemaker engineering, Yasutaka Kurata, Hiroyuki Matsuda, Ichiro Hisatome, Toshishige Shibamoto, Am J Physiol Heart Circ Physiol292:H701-H718Jan. 2007
  • The sinusoidal pressure during ischemia-reperfusion injury in perfused mouse liver pretreated with or without L-NAME, T.Shibamoto, Z.Ruan, S.Cui, W.Liu, Z-S.Zhao, H.Takano, Y.Kurata, T.Koizumi, K.Kubo, The Journal of surgical research139:30-352007
  • The roles of mast cells and Kupffer cells in rat systemic anaphylaxis, T.Shibamoto, T.Shimo, S.Cui, W.Zhang, H.Takano, Y.Kurata, H.Tsuchida, American journal of physiology. Regulatory, integrative and comparative physiology.293:R2202-R22092007
  • Reduced pulmonary vascular reactivity after cold exposure to acute hypoxia: A role of nitric oxide (NO), (K.Watanabe), T.Koizumi, Z.Ruan, K.Kubo, A.Sakai, T.Shibamoto, High altitude medicine & biology8:43-492007
  • NG-nitro-L-arginine methyl ester, but not methylene blue, attenuates anaphylactic hypotension in anesthetized mice, H.Takano, W.Lui, Z.Zhao, S.Cui, W.Zhang, T.Shibamoto, Journal of pharmacological sciences.104::212-2172007
  • Leukotrienes and cyclooxygenase products mediate anaphylactic venoconstriction in ovalbumin sensitized rat livers, S.Cui, T.Shibamoto, H.Takano, W.Zhang, Y.Kurata, European journal of pharmacology.576:99-1062007
  • Involvement of splanchnic vascular bed in anaphylactic hypotension in anesthetized BALB/c mice, W.Liu, H.Takano, T.Shibamoto, S.Cui, Z-S.Zhao, W.Zhang, Y.Kurata, American journal of physiology. Regulatory, integrative and comparative physiology.293:R1947-19532007
  • Hepatic pre-sinusoidal vessels contract in anaphylactic hypotension in rabbits, N.Karasawa, T.Shibamoto, S.Cui, H.Takano, Y.Kurata, H.Tsuchida, Acta physiologica Scandinavica.189:15-222007
  • Head-down tilt posture attenuates anaphylactic hypotension in mice and rats, Z.Zhao, T.Shibamoto, S.Cui, H.Takano, W.Zhang, Y.Kurata, The journal of physiological sciences : JPS57:269-2742007
  • Effects of L-NAME on thromboxane A2-induced venoconstriction in isolated perfused livers from rat, guinea pig and mouse, S.Cui, T.Shibamoto, Z.Zhao, W.Zhang, H.Takano, Y.Kurata, Vascular pharmacology.47:215-2212007
  • Spreading dilatation in small arteries, H.Takano, Y.Kurata, T.Shibamoto31:127-131Aug. 2006
  • Oxygen consumption, assessed with the oxygen absorption spectrophotometer, decreases independently of venoconstriction during hepatic anaphylaxis in perfused rat liver, S.Cui., T.Shibamoto, Z.Ruan, H.Takano, W.Liu, Y.Kurata, Shock (Augusta, Ga.)26:62-682006
  • NG-nitro-L-arginine methyl ester potentiates anaphylactic venoconstriction in rat perfused livers, T.Shibamoto, T.Ishibashi, T.Shimo, S.Cui, H.Takano, H.Tsuchida, M.Nishio, Y.Kurata, Clinical and experimental pharmacology & physiology.33:1073-10772006
  • Effects of platelet-activating factor, thromboxane A2 and leukotriene D4 on isolated perfused rat liver, S.Cui., T.Shibamoto, W.Liu, H.Takano, Y.Kurata, Prostaglandins & other lipid mediators.80:35-452006
  • Effects of Hct on L-NAME-induced potentiation of anaphylactic presinusoidal constriction in perfused rat livers, S.Cui., T.Shibamoto, W.Liu, H.Takano, Z.S.Zhao, Y.Kurata, Journal of cardiovascular pharmacology.48:827-8332006
  • Involvement of platelet-activating factor and leukotrienes in anaphylactic segmental venoconstriction in ovalbumin sensitized guinea pig livers, T.Shibamoto, Z.Ruan, S.Cui, W.Liu, Y.Kurata, Prostaglandins & other lipid mediators.78:218-230Dec. 2005
  • Effects of nicorandil on monocrotaline-induced pulmonary arterial hypertension in rats, (M.Hongo), E.Mawatari, A.Sakai, Z.Ruan, T.Koizumi, F.Terasawa, Y.Yazaki, O.Kinoshita, U.Ikeda, T.Shibamoto, Journal of cardiovascular pharmacology.46:452-458Oct. 2005
  • Dynamical mechanisms of pacemaker generation in IK1-downregulated human ventricular myocytes: insights from bifurcation analyses of a mathematical model, Y.Kurata, I.Hisatome, H.Matsuda, T.Shibamoto89:2865-2887Oct. 2005
  • Hepatic venoconstriction is involved in anaphylactic hypotension in rats, T.Shibamoto, S.Cui, Z.Ruan, W.Liu, H.Takano, Y.Kurata, American journal of physiology. Heart and circulatory physiology.289:H1436-H1444May 2005
  • Comparison of cardiopulmonary response to endogenous nitric oxide inhibition in pigs inhabited at three levels of altitude, (Z.Ruan), T.Koizumi, A.Sakai, T.Ishizaki, K.Kubo, T.Shibamoto, Z.Wang, European journal of applied physiology.94:93-96May 2005
  • Effects of norepinephrine and histamine on vascular resistance in isolated perfused mouse liver, T.Shibamoto, S.Cui, Z.Ruan, Y.Kurata, Japanese journal of physiology.55:143-148Apr. 2005
  • Anaphylactic hepatic venoconstriction is attenuated by nitric oxide released via shear stress-dependent and -independent mechanisms in guinea pig, T.Shibamoto, Z.Ruan, S.Cui, Y.Kurata, T.Koizumi, K.Kubo, Clinical and experimental pharmacology & physiology.32:288-293Apr. 2005
  • Hepatic venoconstriction is involved in anaphylactic hypotension in rats., SHIBAMOTO Toshishige, Am J Physiol Heart Circ Physiol2005
  • Effects of norepinephrine and histamine on vascular resistance in isolated perfused mouse liver., SHIBAMOTO Toshishige, Jpn J Physiol.2005
  • Effects of nicorandil on monocrotaline-induced pulmonary arterial hypertension in rats., SHIBAMOTO Toshishige, J Cardiovasc Pharmacol2005
  • Dynamical Mechanisms of Pacemaker Generation in IK1-Downregulated Human Ventricular Myocytes: Insights from bifurcation analyses of a mathematical model., SHIBAMOTO Toshishige, Biophysic J2005
  • Comparison of cardiopulmonary response to endogenous nitric oxide inhibition in pigs inhabited at three levels of altitude., SHIBAMOTO Toshishige, Eur J Appl Physiol.2005
  • Anaphylactic hepatic venoconstriction is attenuated by nitric oxide released via shear stress-dependent and -independent mechanisms in Guinea pig., SHIBAMOTO Toshishige, Clin Exp Pharmacol Physiol.2005
  • NO, but not CO, attenuates anaphylaxis-induced postsinusoidal contraction and congestion in guinea pig liver., SHIBAMOTO Toshishige, Am J Physiol Regul Integr Comp Physiol2004
  • NO, but not CO, attenuates anaphylaxis-induced postsinusoidal contraction and congestion in guinea pig liver,  Z. Ruan., T. Shibamoto, *T. Shimo, *H. Tsuchida, *M. Nishio, et al., American journal of physiology. Regulatory, integrative and comparative physiology.286:R94-R1002004
  • Effects of platelet-activating factor and thromboxane A2 on isolated perfused-guinea pig liver., SHIBAMOTO Toshishige, Prostaglandins Other Lipid Mediators2004
  • Effects of platelet-activating factor and thromboxane A2 on isolated perfused-guinea pig liver,  Z. Ruan, T. Shibamoto, *T. Shimo, *H. Tsuchida, Y. Kurata, T. Ogura, et al., Prostaglandins & other lipid mediators.73:73-852004
  • Effects of hematocrit and norepinephrine on segmental vascular resistance distribution in isolated perfused rat livers., SHIBAMOTO Toshishige, Am J Physiol Heart Circ Physiol.2004
  • Effects of Hct and norepinephrine on segmental vascular resistance distribution in isolated perfused rat livers, (C. Kamikado), T. Shibamoto, et al., American journal of physiology. Heart and circulatory physiology.286:H121-H1302004
  • Effects of Angiotensin II on sustained outward currents in rat ventricular myocytes., SHIBAMOTO Toshishige, Pflugers Arch2004
  • Effects of Angiotensin II on sustained outward currents in rat ventricular myocytes,  H. Matsuda, Y. Kurata, T. Shibamoto, et al., Pflugers Archiv : European journal of physiology.448:54-622004
  • Different hepatic vascular response to noradrenaline and histamine between guinea pig and rat,  T. Shibamoto, *T. Shimo, *H. Tsuchida, Y. Kurata, T. Ogura, et al., Acta physiologica Scandinavica.180:255-2632004
  • Roles of L-type Ca2+ and delayed-rectifier K+ currents in sinoatrial node pacemaking:insights from stability and bifurcation analyses of a mathematical model, Y. Kurata, S. Imanishi, T. Shibamoto, et al., American journal of physiology. Heart and circulatory physiology.285: H2804-H28192003
  • Roles of L-type Ca2+ and delayed-rectifier K+ currents in sinoatrial node pacemaking: insights from stability and bifurcation analyses of a mathematical model., SHIBAMOTO Toshishige, Am J Physiol Heart Circ Physiol.2003
  • Osmosensitive properties of rapid and slow delayed rectifier K+ currents in guinea-pig heart cells, T. Ogura, H. Matsuda, T. Shibamoto, et al., Clinical and experimental pharmacology & physiology.30: 616-6222003
  • Osmomseusitive properties of rapid and slow delayed rectifier K+ currents in guinea-pig heart cells , SHIBAMOTO Toshishige, Clin. Exp. Pharmacol. Physiol.2003
  • Sarcolemmal hydraulic conductivity of guinea-pig and rat ventricular myocytes, T. Ogura, H. Matsuda, S. Imanishi, T. Shibamoto, Cardiovascular research.54: 590-6002002
  • Sarcolemmal Hydraulic conductivity of guinea-pig and not ventricular myocytes, SHIBAMOTO Toshishige, Cardiovascular Research2002
  • Sarcolemmal Hydraulic conductivity of guinea-pig and not ventricular myocytes, SHIBAMOTO Toshishige, Cardiovascular Research2002
  • Osmometric and water-transporting properties of guinea pig cardiac myocytes , SHIBAMOTO Toshishige, Jpn. J. Physiol.2002
  • Osmometric and water-transporting properties of guinea pig cardiac myocytes, T. Ogura, S. Imanishi, T. Shibamoto, Japanese journal of physiology.52: 333-3422002
  • Osmometric and water-transporting properties of guinea pig cardiac myocytes, SHIBAMOTO Toshishige, Jpn. J. Physiol.2002
  • Effects of resuscitation with hydroxyethyl starch (HES) on pulmonary hemodyonamics and lung lymph balance in hemorrhagic sheep : comparative study of low and high molecular HES, SHIBAMOTO Toshishige, Resuscitation2002
  • Effects of resuscitation with hydroxyethyl starch (HES) on pulmonary hemodyonamics and lung lymph balance in hemorrhagic sheep : comparative study of low and high molecular HES, SHIBAMOTO Toshishige, Resuscitation2002
  • Effects of resuscitation with hydroxyethyl starch (HES) on pulmonary hemodynamics and lung lymph balance in hemorrhagic sheep; comparative study of low and high molecular HES, (T. Kaneki), T. Shibamoto, et al., Resuscitation52: 101-1082002
  • Dynamical description of sinoatrial node pacemaking: improved mathematical model for primary pacemaker cell., SHIBAMOTO Toshishige, Am J Physiol Heart Circ Physiol2002
  • Dynamical description of sinoatrial node pacemaking: improved mathematical model for primary pacemaker cell, Y. Kurata, S. Imanishi, T. Shibamoto, et al., American journal of physiology. Heart and circulatory physiology.283: H2074-H21012002
  • Dynamic description of sinoatrial node pacemaking: improved mathematical model for primary pacemaker cell , SHIBAMOTO Toshishige, Am. J. Physiol. Heart Circ. Physiol.2002
  • Dynamic description of sinoatrial node pacemaking: improved mathematical model for primary pacemaker cell, SHIBAMOTO Toshishige, Am. J. Physical. Heart Circ. Physiol.2002
  • Effects of growth hormone follwoing chronic angioteusin-converting enzyme inhibition in chronic heart failure : their relation to infarct size, SHIBAMOTO Toshishige, Cardiovasc. Drug Ther.2001
  • Effects of growth hormone follwoing chronic angioteusin-converting enzyme inhibition in chronic heart failure : their relation to infarct size, SHIBAMOTO Toshishige, Cardiovasc. Drug Ther.2001
  • Effects of growth hormone following chronic angiotensin-converting enzyme inhibition in chronic heart failure: their relation to infarct size, (M. Hongo), T. Shibamoto, et al., Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy.15: 241-2492001
  • Activation of background membrance conductance by the throsine kinase inhibitor Tyrophostin A23 and its inactive analog Tyrphostin A1 in guinea-pig ventricular myocytes, SHIBAMOTO Toshishige, Jpn. J. Pharmacol.2001
  • Activation of background membrance conductance by the throsine kinase inhibitor Tyrophostin A23 and its inactive analog Tyrphostin A1 in guinea-pig ventricular myocytes, SHIBAMOTO Toshishige, Jpn. J. Pharmacol.2001
  • Lung lymph response to overinfusion with hydroxyethyl starch in sheep : comparative studies of high and low molecular weight compounds, SHIBAMOTO Toshishige, Acta Anaesthesiol. Scand.2000
  • Increased sinusoidal pressure is associated with early liver weight gain in ischemia-reperfusion injury in isolated perfused nat liver, SHIBAMOTO Toshishige, Journal of Surgical Research2000
  • Presinusoidal vessels predominantly contract in response to novepinephrine, histamine, and KCL in rabbit liver, SHIBAMOTO Toshishige, Journal of Applied Physiology1999
  • Endothelin receptor blockade attenuates air embolization-induced pulmonary hypertension in sheep., SHIBAMOTO Toshishige, European Journal of Pharmacology1999
  • Effect of ONO-5046, a specific neutrophil elastase inhibitor, on the phorbol myristate acetate-induced injury in isolated dog lung, SHIBAMOTO Toshishige, Experimental Lung Research1999
  • The role of endogenous nitric oxide in the sympathetic and hemodynamic response to platelet activating factor-induced hypotension in anesthetized dogs, SHIBAMOTO Toshishige, Shock1998
  • Lecithinized superoxide dismutase attenuates phorbol myristate acetate-induced injury in isolated dog lung., SHIBAMOTO Toshishige, Eur. J. Pharmacol.1998
  • Role of circulating blood components and thromboxane in anaphylactic vasoconstriction in isolated canine lungs., SHIBAMOTO Toshishige, J. Appl. Physiol.1997
  • Endothelin-1 selectively contracts portol vein through both ETA and ETB receptors in isolated rabbit liver, SHIBAMOTO Toshishige, Am. J. Physiol.1997
  • Effect of platelet-activating factor on hepatic capillary pressure in isoloted dog liver, SHIBAMOTO Toshishige, Prostaglandind Leukot. Essent. Fotty Acids1997
  • Thromboxane A2 analogue contracts predominantly the hepatic veins in isolated canine liver, SHIBAMOTO Toshishige, Prostaglandins1996
  • The effects of sevoflurane, enflurane, and isoflurane on baroreceptor-sympathetic reflex in rabbits., SHIBAMOTO Toshishige, Anesth. Analg.1996
  • Participation of nitric oxide in the sympathetic response to anaphylactic hypotension in anesthetized dogs, SHIBAMOTO Toshishige, Neuroscience Letter1996
  • Hepatic capillary pressure is estimated using triple vascular occlusion wethod in isolated canine liver, SHIBAMOTO Toshishige, American Journal of Physiology1996
  • Differential regional sympathetic responses to somatic stimulation in anesthetized dogs, SHIBAMOTO Toshishige, Journal of Autouomic Nervous Sgstem1996
  • Changes in tissue blood flow and sympathetic activities to various organs during prolonged hemorrhagic hypotension in monkeys, SHIBAMOTO Toshishige, Journal of Autouomic Nervous System1996
  • rBPI23 attenuates endotoxin-induced cardiovascular depression in awake rabbits., SHIBAMOTO Toshishige, Shock.1995
  • Suppression of sympathetic nervous system is involved in hypotension and bradycardia during hemofiltration in anesthetized dogs., SHIBAMOTO Toshishige, Can. J. Physiol. Pharmacol.1995
  • No effects of large doses of catecholamines on vascular permeability in isolated blood-perfused dog lungs., SHIBAMOTO Toshishige, Acta. Physiol. Scand.1995
  • Effects of thromboxane A2 analogue on vascular resistance distribution and permeability in isolated blood-perfused dog lungs., SHIBAMOTO Toshishige, Lung1995
  • Baroreflex attenuation after hypotension induced by vena caval occlusion in anesthetized dogs., SHIBAMOTO Toshishige, Am. J. Physiol.1995
  • Role of hypogastric nerve activity in opposum internal aual sphincter function : Influence of Surgical and chemical deuervation, SHIBAMOTO Toshishige, J. Pharmacol. Exp. Ther.1994
  • Hepatic vascular response to anaphylaxis in isolated canine liver, SHIBAMOTO Toshishige, Am. J. Physiol.1994
  • Pulmonary anaphylaxis in isolated canine lungs, SHIBAMOTO Toshishige, Pulmonary Circulation Research 19921993
  • PAF increases capillary pressure but not vascular permeability in isolated blood perfused-canine lungs., SHIBAMOTO Toshishige, American Journal of Physiology1993
  • Differential control of sympathetic outflow to kidney, heart, adrenal gland, and liver during systemic hypotension induced by cardiac tamponade in anesthetized dogs., SHIBAMOTO Toshishige, Circulatory Shock1993
  • Pulmonary vascular response to anaphylaxis in isolated canine lungs, SHIBAMOTO Toshishige, American Journal of Physiology1992
  • Acute effect of hypobaria and hypoxia on renal nerve activity in anesthetized rabbits, SHIBAMOTO Toshishige, Acta Physiologica Scandinavica1992
  • PO2 modulation of paraquat induced microvascular injury in isolated dog lungs, SHIBAMOTO Toshishige, Journal of Applied Physiology1990
  • Fructose 1, 6 - diphosphate augments paraquat injury in isolated dog lungs, SHIBAMOTO Toshishige, Journal of Applied Physiology1990
  • Derecruitment of filtration surface area in paraquat-injured isolated dog lungs, SHIBAMOTO Toshishige, Journal of Applied Physiology1990
  • Platelike and globelike inclusion bodies associated with rough endoplasmic reticulum in alveolar type 2 cells of the sheep, SHIBAMOTO Toshishige, Anatomical Record1989
  • Electron microscopic studies on the alterations in the alveoli of paraquat-administered sheep, with special reference to the relationship between lung lymph dynamics and ultrastructure., SHIBAMOTO Toshishige, Journal of Clinical Electron Microscopy1987
  • Acute effect of paraquat on lung fluid balance and prostanoid production in awake sheep, SHIBAMOTO Toshishige, American Review of Respiratory Disease1986
  • Mouse Anaphylactic Hypotension Is Characterized by Initial Baroreflex Independent Renal Sympathoinhibition Followed by Sustained Renal Sympathoexcitation., Zhang T, Tanida M, Uchida K, Suzuki Y, Yang W, Kuda Y, Kurata Y, Tominaga M, Shibamoto T., frontiers in Physiology8:6692017
  • Biphasic Renal Sympathetic Response to Hemorrhagic Hypotension in Mice., Zhang T, Tanida M, Uchida K, Suzuki Y, Yang W, Kuda Y, Kurata Y, Tominaga M, Shibamoto T., Shock48:576-5822017
  • Blockade of β2-adrenoceptor, rather than β1-adrenoceptor, deteriorates cardiac anaphylaxis in isolated blood-perfused rat hearts., Kuda Y, Shibamoto T, Yang W, Zhang T, Tanida M, Kurata Y., Cardiol J24:403-4082017
  • Dynamical mechanisms of phase-2 early afterdepolarizations in human ventricular myocytes: insights from bifurcation analyses of two mathematical models., Kurata Y, Tsumoto K, Hayashi K, Hisatome I, Tanida M, Kuda Y, Shibamoto T., Am J Physiol Heart Circ Physiol312:H106-H1272017
  • Gastric vascular and motor responses to anaphylactic hypotension in anesthetized rats, in comparison to those with hemorrhagic or vasodilator-induced hypotension., Kuda Y, Shibamoto T, Zhang T, Yang W, Tanida M, Kurata Y., J Physiol Sci68:253-2602017
  • Renal response to anaphylaxis in anesthetized rats and isolated perfused rat kidneys: roles of nitric oxide., Mukai K, Kuda Y, Shibamoto T, Tanida M, Kurata Y, Yokoyama H., The Journal of Physiological Sciences(in press):(in press)2018


Copyright (c) MEDIA FUSION Co.,Ltd. All rights reserved.