KOYA Daisuke

Researcher Profile & Settings

Research

Overview of research:
diabetes, hypertension, obesity, aging

Education

• Shiga University of Medical Science

Degree

• Ph.D in Medicine

Research Activities

Published Papers

• Eplerenone prevented obesity-induced inflammasome activation and glucose intolerance, (Tsutomu.Wada), Akari.Ishikawa, Eri.Watanabe, Yuto.Nakamura, Yusuke.Aruga, Hayate.Hasegawa, Yasuhiro.Onogi, Hiroe.Honda, Yoshinori.Nagai, Kiyoshi.Takatsu, Yoko.Ishii, Masakiyo.Sasahara, Daisuke.Koya, Hiroshi.Tsuneki, Toshiyasu.Sasaoka, JOURNAL OF ENDOCRINOLOGY, 235:179-191, Dec. 2017
  DOI:10.1530/JOE-17-0351
• Cyclic and intermittent very low-protein diet can have beneficial effects against advanced diabetic nephropathy in Wistar fatty (fa/fa) rats, an animal model of type 2 diabetes and obesity, Munehiro.Kitada, Yoshio.Ogura, Taeko.Suzuki, Itaru.Monno, Keizo.Kanasaki, Ai.Watanabe, Daisuke.Koya, NEPHROLOGY, 22:1030-1034, Dec. 2017
  DOI:10.1111/nep.13152
• The Effect of Piceatannol from Passion Fruit (Passiflora edulis) Seeds on Metabolic Health in Humans, Munehiro.Kitada, Yoshio.Ogura, Hiroko.Maruki-Uchida, Masahiko.Sai, Taeko.Suzuki, Keizo.Kanasaki, Yuna.Hara, Hiromi.Seto, Yuka.Kuroshima, Itaru.Monno, Daisuke.Koya, NUTRIENTS, 9:1142, Oct. 2017
  DOI:10.3390/nu9101142
• Impact of empagliflozin on diabetic kidney disease, Daisuke.Koya, JOURNAL OF DIABETES INVESTIGATION, 8:658-660, Sep. 2017
  DOI:10.1111/jdi.12615
• Deficiency in catechol-o-methyltransferase is linked to a disruption of glucose homeostasis in mice, Megumi.Kanasaki, Swayam Prakash.Srivastava, Fan.Yang, Ling.Xu, Sumiyo.Kudoh, Munehiro.Kitada, Norikazu.Ueki, Hyoh.Kim, Jinpeng.Li, Satoru.Takeda, Keizo.Kanasaki, Daisuke.Koya, SCIENTIFIC REPORTS, 7:7927, Aug. 2017
  DOI:10.1038/s41598-017-08513-w
• FGFR1 is critical for the anti-endothelial mesenchymal transition effect of N-acetyl-seryl-aspartyl-lysyl-proline via induction of the MAP4K4 pathway, Jinpeng.Li, Sen.Shi, Swayam Prakash.Srivastava, Munehiro.Kitada, Takako.Nagai, Kyoko.Nitta, Miyuki.Kohno, Keizo.Kanasaki, Daisuke.Koya, CELL DEATH and DISEASE, 8:e2965, Aug. 2017
  DOI:10.1038/cddis.2017.353
• Regulating Autophagy as a Therapeutic Target for Diabetic Nephropathy., Munehiro.Kitada, Yoshio.Ogura, Itaru.Monno, Daisuke.Koya, Current Diabetes Reports, 17:53, Jul. 2017
  DOI:10.1007/s11892-017-0879-y
• Anagliptin ameliorates albuminuria and urinary liver-type fatty acid-binding protein excretion in patients with type 2 diabetes with nephropathy in a glucose-lowering-independent manner., Munehiro.Kitada, Shin-ichi.Tsuda, Kazunori.Konishi, Ai.Takeda-Watanabe, Mizue.Fujii, Keizo.Kanasaki, Makoto.Nishizawa, Atsushi.Nakagawa, Daisuke.Koya, BMJ Open Diabetes Research & Care, 5:e000391, Jul. 2017
  DOI:10.1136/bmjdrc-2017-000391
• PDGFRβ Regulates Adipose Tissue Expansion and Glucose Metabolism via Vascular Remodeling in Diet-Induced Obesity., (Yasuhiro.Onogi), Tsutomu.Wada, Chie.Kamiya, Kento.Inata, Takatoshi.Matsuzawa, Yuka.Inaba, Kumi.Kimura, Hiroshi.Inoue, Seiji.Yamamoto, Yoko.Ishii, Daisuke.Koya, Hiroshi.Tsuneki, Masakiyo.Sasahara, Toshiyasu.Sasaoka, Diabetes, 66:1008-1021, Apr. 2017
  DOI:10.2337/db16-0881
• A randomized controlled study of finerenone versus placebo in Japanese patients with type 2 diabetes mellitus and diabetic nephropathy, (Shigehiro.Katayama), Daishiro.Yamada, Mikihiro.Nakayama, Takashi.Yamada, Masafumi.Myoishi, Masaharu.Kato, Christina.Nowack, Peter.Kolkhof, Yoshimitsu.Yamasaki, on behalf of the ARTS-DN Japan Study Group: Daisuke.Koya, JOURNAL OF DIABETES AND ITS COMPLICATIONS, 31:758-765, Apr. 2017
• Dipeptidyl peptidase-4 inhibition and renoprotection: the role of antifibrotic effects, Yuta.Takagaki, Daisuke.Koya, Keizo.Kanasaki, CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 26:56-66, Jan. 2017
  DOI:10.1097/MNH.0000000000000291
• Catechol-O-Methyltransferase Deficiency Leads to Hypersensitivity of the Pressor Response Against Angiotensin II., Norikazu.Ueki, Keizo.Kanasaki, Megumi.Kanasaki, Satoru.Takeda, Daisuke.Koya, Hypertension, 69:1156-1164, Jun. 2017
  DOI:10.1161/HYPERTENSIONAHA.117.09247
• MicroRNA148b-3p inhibits mTORC1-dependent apoptosis in diabetes by repressing TNFR2 in proximal tubular cells., (S.Kuwagata), S.Kume, M.Chin-Kanasaki, H.Araki, S.Araki, J.Nakazawa, T.Sugaya, D.Koya, M.Haneda, H.Maegawa, T.Uzu, Kidney international, 90:1211-1225, Dec. 2016
  DOI:10.1016/j.kint.2016.06.036
• Comparative effects of direct renin inhibitor and angiotensin receptor blocker on albuminuria in hypertensive patients with type 2 diabetes. A randomized controlled trial, (T.Uzu), S.Araki, A.Kashiwagi, M.Haneda, D.Koya, H.Yokoyama, Y.Kida, M.Ikebuchi, T.Nakamura, M.Nishimura, N.Takahara, T.Obata, N.Omichi, K.Sakamoto, R.Shingu, H.Taki, Y.Nagai, H.Tokuda, M.Kitada, M.Misawa, A.Nishiyama, H.Kobori, H.Maegawa, The Shiga Committee for Preventing Diabetic Nephropathy, PLoS ONE, 11:e0164936-e0164936, Dec. 2016
• Rodent models of diabetic nephropathy: their utility and limitations., M.Kitada, Y.Ogura, D.Koya, International journal of nephrology and renovascular disease, 9:279-290, Nov. 2016
• Hypothalamic AMP-activated protein kinase regulates biphasic insulin secretion from pancreatic β cells during fasting and in type 2 diabetes, (S.Kume), M.Kondo, S.Maeda, Y.Nishio, T.Yanagimachi, Y.Fujita, M.Haneda, K.Kondo, A.Sekine, S.Araki, H.Araki, M.Chin-Kanasaki, S.Ugi, D.Koya, S.Kitahara, K.Maeda, A.Kashiwagi, T.Uzu, H.Maegawa, EBioMedicine, 13:168-180, Nov. 2016
• The protective role of sirt1 in vascular tissue: its relationship to vascular aging and atherosclerosis., M.Kitada, Y.Ogura, D.Koya, Aging(Albany NY), 8:2290-2307, Oct. 2016
  DOI:10.18632/aging.101068
• Rapid enlargement of an intracranial germ cell tumor after gonadotropin hormone therapy, (Y.Sasagawa), O.Tachibana, A.Nakagawa, S.Nakada, T.Nojima, D.Koya, H.Iizuka, JOURNAL OF CLINICAL NEUROSCIENCE, 31:185-188, Sep. 2016
  DOI:10.1016/j.jocn.2016.01.033
• Rationale and design of the standard versus intensive statin therapy for hypercholesterolemic patients with diabetic retinopathy (EMPATHY) study: a randomized controlled trial, (K.Ueshima), H.Itoh, N.Kanazawa, I.Komuro, R.Nagai, M.Takeuchi, T.Yamazaki, EMPATHY study group, D.Koya, A.Nakagawa, M.Nishizawa, M.Kitada, S.Tsuda, K.Konishi, 23:976-990, Aug. 2016
• Effect of antifibrotic microRNAs crosstalk on the action of N-acetyl-seryl-aspartyl-lysyl-proline in diabetes-related kidney fibrosis., S.P.Srivastava, S.Shi, M.Kanasaki, T.Nagai, M.Kitada, J.He, Y.Nakamura, Y.Ishigaki, K.Kanasaki, D.Koya, Scientific reports, 6:29884-29884, Jul. 2016
  DOI:10.1038/srep29884
• A very-low-protein diet ameliorates advanced diabetic nephropathy through autophagy induction by suppression of the mTORC1 pathway in Wistar fatty rats, an animal model of type 2 diabetes and obesity., M.Kitada, Y.Ogura, T.Suzuki, S.Sen, S.M.Lee, K.Kanasaki, S.Kume, D.Koya, Diabetologia, 59:1307-1317, Jun. 2016
  DOI:10.1007/s00125-016-3925-4
• The protective effect of a low-protein diet against tubulo-interstitial damage in diabetic kidneys, M.Kitada, Y.Ogura, D.Koya, Cellular & Molecular Medicine: Open access, 2:6-7, May. 2016
• Impaired podocyte autophagy exacerbates proteinuria in diabetic nephropathy., (A.Tagawa), M.Yasuda, S.Kume, K.Yamahara, J.Nakazawa, M.Chin-Kanasaki, H.Araki, S.Araki, D.Koya, K.Asanuma, EH.Kim, M.Haneda, N.Kajiwara, K.Hayashi, H.Ohashi, S.Ugi, H.Maegawa, T.Uzu, Diabetes, 65:755-767, Mar. 2016
  DOI:10.2337/db15-0473
• Oral administration of N-Acetyl-seryl-aspartyl-lysyl-proline ameliorates kidney disease in both type 1 and type 2 diabetic mice via a therapeutic regimen., K.Nitta, Shi Sen, T.Nagai, M.Kanasaki, M.Kitada, Srivastava Swayam Prakash, M.Haneda, K.Kanasaki, D.Koya, BioMed research international, 2016:9172157-9172157, Mar. 2016
  DOI:10.1155/2016/9172157
• Dipeptidyl peptidase-4 and kidney fibrosis in diabetes., S.Shi, D.Koya, K.Kanasaki, Fibrogenesis & tissue repair, 9:1-1, Feb. 2016
  DOI:10.1186/s13069-016-0038-0
• Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)., (DJ.Klionsky), K.Abdelmohsen, A.Abe, MJ.Abedin, H.Abeliovich, A.Acevedo Arozena, H.Adachi, CM.Adams, PD.Adams, K.Adeli, PJ.Adhihetty, SG.Adler, G.Agam, R.Agarwal, MK.Aghi, M.Agnello, P.Agostinis, PV.Aguilar, J.Aguirre-Ghiso, EM.Airoldi, S.Ait-Si-Ali, T.Akematsu, ET.Akporiaye, M.Al-Rubeai, GM.Albaiceta, C.Albanese, D.Albani, ML.Albert, J.Aldudo, H.Algül, M.Alirezaei, I.Alloza, A.Almasan, M.Almonte-Beceril, ES.Alnemri, C.Alonso, N.Altan-Bonnet, DC.Altieri, S.Alvarez, L.Alvarez-Erviti, S.Alves, G.Amadoro, A.Amano, C.Amantini, S.Ambrosio, I.Amelio, AO.Amer, M.Amessou, A.Amon, Z.An, FA.Anania, SU.Andersen, UP.Andley, CK.Andreadi, N.Andrieu-Abadie, A.Anel, DK.Ann, S.Anoopkumar-Dukie, M.Antonioli, H.Aoki, N.Apostolova, S.Aquila, K.Aquilano, K.Araki, E.Arama, A.Aranda, J.Araya, A.Arcaro, E.Arias, H.Arimoto, AR.Ariosa, JL.Armstrong, T.Arnould, I.Arsov, K.Asanuma, V.Askanas, E.Asselin, R.Atarashi, SS.Atherton, JD.Atkin, LD.Attardi, P.Auberger, G.Auburger, L.Aurelian, R.Autelli, L.Avagliano, ML.Avantaggiati, L.Avrahami, S.Awale, N.Azad, T.Bachetti, JM.Backer, DH.Bae, JS.Bae, ON.Bae, SH.Bae, EH.Baehrecke, SH.Baek, S.Baghdiguian, A.Bagniewska-Zadworna, H.Bai, J.Bai, XY.Bai, Y.Bailly, KN.Balaji, W.Balduini, A.Ballabio, R.Balzan, R.Banerjee, G.Bánhegyi, H.Bao, B.Barbeau, MD.Barrachina, E.Barreiro, B.Bartel, A.Bartolomé, DC.Bassham, MT.Bassi, RC Jr.Bast, A.Basu, MT.Batista, H.Batoko, M.Battino, K.Bauckman, BL.Baumgarner, KU.Bayer, R.Beale, JF.Beaulieu, GR Jr.Beck, C.Becker, JD.Beckham, PA.Bédard, PJ.Bednarski, TJ.Begley, C.Behl, C.Behrends, GM.Behrens, KE.Behrns, E.Bejarano, A.Belaid, F.Belleudi, G.Bénard , G.Berchem, D.Bergamaschi, M.Bergami, B.Berkhout, L.Berliocchi, A.Bernard, M.Bernard, F.Bernassola, A.Bertolotti, AS.Bess, S.Besteiro, S.Bettuzzi, S.Bhalla, S.Bhattacharyya, SK.Bhutia, C.Biagosch, MW.Bianchi, M.Biard-Piechaczyk, V.Billes, C.Bincoletto, B.Bingol, SW.Bird, M.Bitoun, I.Bjedov, C.Blackstone, L.Blanc, GA.Blanco, HK.Blomhoff, E.Boada-Romero, S.Böckler, M.Boes, K.Boesze-Battaglia, LH.Boise, A.Bolino, A.Boman, P.Bonaldo, M.Bordi, J.Bosch, LM.Botana, J.Botti, G.Bou, M.Bouché, M.Bouchecareilh, MJ.Boucher, ME.Boulton, SG.Bouret, P.Boya, M.Boyer-Guittaut, PV.Bozhkov, N.Brady, VM.Braga, C.Brancolini, GH.Braus, Pedro JM.Bravo-San, LA.Brennan, EH.Bresnick, P.Brest, D.Bridges, MA.Bringer, M.Brini, GC.Brito, B.Brodin, PS.Brookes, EJ.Brown, K.Brown, HE.Broxmeyer, A.Bruhat, PC.Brum, JH.Brumell, N.Brunetti-Pierri, RJ.Bryson-Richardson, S.Buch, AM.Buchan, H.Budak, DV.Bulavin, SJ.Bultman, G.Bultynck, V.Bumbasirevic, Y.Burelle, RE.Burke, M.Burmeister, P.Bütikofer, L.Caberlotto, K.Cadwell, M.Cahova, D.Cai, J.Cai, Q.Cai, S.Calatayud, N.Camougrand, M.Campanella, GR.Campbell, M.Campbell, S.Campello, R.Candau, I.Caniggia, L.Cantoni, L.Cao, AB.Caplan, M.Caraglia, C.Cardinali, SM.Cardoso, JS.Carew, LA.Carleton, CR.Carlin, S.Carloni, SR.Carlsson, D.Carmona-Gutierrez, LA.Carneiro, O.Carnevali, S.Carra, A.Carrier, B.Carroll, C.Casas, J.Casas, G.Cassinelli, P.Castets, S.Castro-Obregon, G.Cavallini, I.Ceccherini, F.Cecconi, AI.Cederbaum, V.Ceña, S.Cenci, C.Cerella, D.Cervia, S.Cetrullo, H.Chaachouay, HJ.Chae, AS.Chagin, CY.Chai, G.Chakrabarti, G.Chamilos, EY.Chan, MT.Chan, D.Chandra, P.Chandra, CP.Chang, RC.Chang, TY.Chang, JC.Chatham, S.Chatterjee, S.Chauhan, Y.Che, ME.Cheetham, R.Cheluvappa, CJ.Chen, G.Chen, GC.Chen, G.Chen, H.Chen, JW.Chen, JK.Chen, M.Chen, M.Chen, P.Chen, Q.Chen, Q.Chen, SD.Chen, S.Chen, SS.Chen, W.Chen, WJ.Chen, WQ.Chen, W.Chen, X.Chen, YH.Chen, YG.Chen, Y.Chen, Y.Chen, Y.Chen, YJ.Chen, YQ.Chen, Y.Chen, Z.Chen, Z.Chen, A.Cheng, CH.Cheng, H.Cheng, H.Cheong, S.Cherry, J.Chesney, CH.Cheung, E.Chevet, HC.Chi, SG.Chi, F.Chiacchiera, HL.Chiang, R.Chiarelli, M.Chiariello, M.Chieppa, LS.Chin, M.Chiong, GN.Chiu, DH.Cho, SG.Cho, WC.Cho, YY.Cho, YS.Cho, AM.Choi, EJ.Choi, EK.Choi, J.Choi, ME.Choi, SI.Choi, TF.Chou, S.Chouaib, D.Choubey, V.Choubey, KC.Chow, K.Chowdhury, CT.Chu, TH.Chuang, T.Chun, H.Chung, T.Chung, YL.Chung, YJ.Chwae, V.Cianfanelli, R.Ciarcia, IA.Ciechomska, MR.Ciriolo, M.Cirone, S.Claerhout, MJ.Clague, J.Clària, PG.Clarke, R.Clarke, E.Clementi, C.Cleyrat, M.Cnop, EM.Coccia, T.Cocco, P.Codogno, J.Coers, EE.Cohen, D.Colecchia, L.Coletto, NS.Coll, E.Colucci-Guyon, S.Comincini, M.Condello, KL.Cook, GH.Coombs, CD.Cooper, JM.Cooper, I.Coppens, MT.Corasaniti, M.Corazzari, R.Corbalan, E.Corcelle-Termeau, MD.Cordero, C.Corral-Ramos, O.Corti, A.Cossarizza, P.Costelli, S.Costes, SL.Cotman, A.Coto-Montes, S.Cottet, E.Couve, LR.Covey, LA.Cowart, JS.Cox, FP.Coxon, CB.Coyne, MS.Cragg, RJ.Craven, T.Crepaldi, JL.Crespo, A.Criollo, V.Crippa, MT.Cruz, AM.Cuervo, JM.Cuezva, T.Cui, PR.Cutillas, MJ.Czaja, MF.Czyzyk-Krzeska, RK.Dagda, U.Dahmen, C.Dai, W.Dai, Y.Dai, KN.Dalby, Valle L.Dalla, G.Dalmasso, M.D'Amelio, M.Damme, A.Darfeuille-Michaud, C.Dargemont, VM.Darley-Usmar, S.Dasarathy, B.Dasgupta, S.Dash, CR.Dass, HM.Davey, LM.Davids, D.Dávila, RJ.Davis, TM.Dawson, VL.Dawson, P.Daza, J.de Belleroche, P.de Figueiredo, RC.de Figueiredo, J.de la Fuente, L.De Martino, A.De Matteis, GR.De Meyer, A.De Milito, M.De Santi, W.de Souza, V.De Tata, D.De Zio, J.Debnath, R.Dechant, JP.Decuypere, S.Deegan, B.Dehay, Bello B.Del, Re DP.Del, R.Delage-Mourroux, LM.Delbridge, L.Deldicque, E.Delorme-Axford, Y.Deng, J.Dengjel, M.Denizot, P.Dent, CJ.Der, V.Deretic, B.Derrien, E.Deutsch, TP.Devarenne, RJ.Devenish, Bartolomeo S.Di, N.Di Daniel, F.Di Domenic, A.Di Nard, S.Di Paol, A.Di Pietr, L.Di Renz, A.DiAntonio, G.Díaz-Araya, I. Díaz-Laviada, MT.Diaz-Meco, J.Diaz-Nido, CA.Dickey, RC.Dickson, M.Diederich, P.Digard, I.Dikic, SP.Dinesh-Kumar, C.Ding, WX.Ding, Z.Ding, L.Dini, JH.Distler, A.Diwan, M.Djavaheri-Mergny, K.Dmytruk, RC.Dobson, V.Doetsch, K.Dokladny, S.Dokudovskaya, M.Donadelli, XC.Dong, X.Dong, Z.Dong, TM Jr.Donohue, KS.Doran, G.D'Orazi, GW 2nd.Dorn, V.Dosenko, S.Dridi, L.Drucker, J.Du, LL.Du, L.Du, A.du Toit, P.Dua, L.Duan, P.Duann, VK.Dubey, MR.Duchen, MA.Duchosal, H.Duez, I.Dugail, VI.Dumit, MC.Duncan, EA.Dunlop, WA Jr.Dunn, N.Dupont, L.Dupuis, RV.Durán, TM.Durcan, S.Duvezin-Caubet, U.Duvvuri, V.Eapen, D.Ebrahimi-Fakhari, A.Echard, L.Eckhart, CL.Edelstein, AL.Edinger, L.Eichinger, T.Eisenberg, A.Eisenberg-Lerner, NT.Eissa, WS.El-Deiry, V.El-Khoury, Z.Elazar, H.Eldar-Finkelman, CJ.Elliott, E.Emanuele, U.Emmenegger, N.Engedal, AM.Engelbrecht, S.Engelender, JM.Enserink, R.Erdmann, J.Erenpreisa, R.Eri, JL.Eriksen, A.Erman, R.Escalante, EL.Eskelinen, L.Espert, L.Esteban-Martínez, TJ.Evans, M.Fabri, G.Fabrias, C.Fabrizi, A.Facchiano, NJ.Færgeman, A.Faggioni, WD.Fairlie, C.Fan, D.Fan, J.Fan, S.Fang, M.Fanto, A.Fanzani, T.Farkas, M.Faure, FB.Favier, H.Fearnhead, M.Federici, E.Fei, TC.Felizardo, H.Feng, Y.Feng, Y.Feng, TA.Ferguson, ÁF.Fernández, MG.Fernandez-Barrena, JC.Fernandez-Checa, A.Fernández-López, ME.Fernandez-Zapico, O.Feron, E.Ferraro, CV.Ferreira-Halder, L.Fesus, R.Feuer, FC.Fiesel, EC.Filippi-Chiela, G.Filomeni, GM.Fimia, JH.Fingert, S.Finkbeiner, T.Finkel, F.Fiorito, PB.Fisher, M.Flajolet, F.Flamigni, O.Florey, S.Florio, RA.Floto, M.Folini, C.Follo, EA.Fon, F.Fornai, F.Fortunato, A.Fraldi, R.Franco, A.Francois, A.François, LB.Frankel, ID.Fraser, N.Frey, DG.Freyssenet, C.Frezza, SL.Friedman, DE.Frigo, D.Fu, JM.Fuentes, J.Fueyo, Y.Fujitani, Y.Fujiwara, M.Fujiya, M.Fukuda, S.Fulda, C.Fusco, B.Gabryel, M.Gaestel, P.Gailly, M.Gajewska, S.Galadari, G.Galili, I.Galindo, MF.Galindo, G.Galliciotti, L.Galluzzi, L.Galluzzi, V.Galy, N.Gammoh, S.Gandy, AK.Ganesan, S.Ganesan, IG.Ganley, M.Gannagé, FB.Gao, F.Gao, JX.Gao, L.García Nannig, E. García Véscovi, M.Garcia-Macía, C.Garcia-Ruiz, AD.Garg, PK.Garg, R.Gargini, NC.Gassen, D.Gatica, E.Gatti, J.Gavard, E.Gavathiotis, L.Ge, P.Ge, S.Ge, PW.Gean, V.Gelmetti, AA.Genazzani, J.Geng, P.Genschik, L.Gerner, JE.Gestwicki, DA.Gewirtz, S.Ghavami, E.Ghigo, D.Ghosh, AM.Giammarioli, F.Giampieri, C.Giampietri, A.Giatromanolaki, DJ.Gibbings, L.Gibellini, SB.Gibson, V.Ginet, A.Giordano, F.Giorgini, E.Giovannetti, SE.Girardin, S.Gispert, S.Giuliano, CL.Gladson, A.Glavic, M.Gleave, N.Godefroy, RM Jr.Gogal, K.Gokulan, GH.Goldman, D.Goletti, MS.Goligorsky, AV.Gomes, LC.Gomes, H.Gomez, C.Gomez-Manzano, R.Gómez-Sánchez, DA.Gonçalves, E.Goncu, Q.Gong, C.Gongora, CB.Gonzalez, P.Gonzalez-Alegre, P.Gonzalez-Cabo, RA.González-Polo, IS.Goping, C.Gorbea, NV.Gorbunov, DR.Goring, AM.Gorman, SM.Gorski, S.Goruppi, S.Goto-Yamada, C.Gotor, RA.Gottlieb, I.Gozes, D.Gozuacik, Y.Graba, M.Graef, GE.Granato, GD.Grant, S.Grant, GL.Gravina, DR.Green, A.Greenhough, MT.Greenwood, B.Grimaldi, F.Gros, C.Grose, 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• Restoration of the hypothalamic-pituitary-adrenal response to hypoglycemia in type 2 diabetes by avoiding chronic hypoglycemia., S.Tsuda, K.Konishi, T.Otoda, T.Nagai, A.Takeda-Watanabe, M.Kanasaki, M.Kitada, A.Nakagawa, M.Nishizawa, K.Kanasaki, D.Koya, Internal medicine, 55:3471-3473, 2016
• Linagliptin but not Sitagliptin inhibited transforming growth factor-β2-induced endothelial DPP-4 activity and the endothelial-mesenchymal transition., S.Shi, K.Kanasaki, D.Koya, Biochemical and biophysical research communications, 471:184-190, 2016
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• The role of angiotensin-converting enzyme inhibition to cimbat kidney fibrosis, K.Nitta, M.kanasaki, K.Kanasaki, D.koya, Journal of Kanazawa Medical University, 40:131-138, Dec. 2015
• Diagnosis and management of diabetic nephropathy, Nihon Rinsyo, 73:2037-2043, Dec. 2015
• Urinary potassium excretion and renal and cardiovascular complications in patients with type 2 diabetes and normal renal function, (S.Araki), M.Haneda, D.Koya, K.Kondo, S.Tanaka, H.Arima, S.Kume, J.Nakazawa, M.Chin-Kanasaki, S.Ugi, H.Kawai, H.Arai, T.Uzu, H.Maegawa, Clinical journal of the American Society of Nephrology : CJASN., 10:2152-2158, Dec. 2015
• Autophagy: A novel therapeutic target for diabetic nephropathy, (S.Kume), D.Koya, Diabetes & Metabolism Journal., 39:451-460, Dec. 2015
• Anti-albuminuric effects of spironolactone in patients with type 2 diabetic nephropathy: a multicenter, randomized clinical trial, (S.Kato), S.Maruyama, H.Makino, J.Wada, D.Ogawa, T.Uzu, H.Araki, D.Koya, K.Kanasaki, Y.Oiso, M.Goto, A.Nishiyama, H.Kobori, E.Imai, M.Ando, S.Matsuo, Clinical and Experimental Nephrology, 19:1098-1106, Dec. 2015
• 1-Methylnicotinamide ameliorates lipotoxicity-induced oxidative stress and cell death in kidney proximal tubular cell, (Y.Tanaka), S.Kume, H.Araki, J.Nakazawa, M.Chin-Kanasaki, S.Araki, F.Nakagawa, D.Koya, M.Haneda, H.Maegawa, T.Uzu, Free Radical Biology & Medicine., 89:831-841, Dec. 2015
• Lamp-2 deficiency prevents high-fat diet-induced obese diabetes via enhancing energy expenditure, (M.Yasuda-Yamahara), S.Kume, K.Yamahara, J.Nakazawa, M.Chin-Kanasaki, H.Araki, S.Araki, D.Koya, M.Haneda, S.Ugi, H.Maegawa, T.Uzu, Biochemical and Biophysical Research Communications, 465:249-255, Sep. 2015
• Interactions of DPP-4 and integrin β1 influences endothelial-to-mesenchymal transition, S.Shi, S.P.Srivastava, M.Kanasaki, J.He, M.Kitada, T.Nagai, K.Nitta, S.Takagi, K.Kanasaki, D.Koya, Kidney International., 88:479-489, Sep. 2015
• Epidermal growth factor receptor signaling and the progression of diabetic nephropathy, D.Koya, Journal of Diabetes Investigation, 6:519-521, Sep. 2015
• The relevance of the renin-angiotensin system in the development of drugs to combat preeclampsia, N.Ueki, S.Takeda, D.Koya, K.Kanasaki, International Journal of Endocrinology [Electronic Resource], 2015:1-12, Apr. 2015
• A new classification of diabetic nephropathy 2014: a report from joint committee on diabetic nephropathy, (M.Haneda), K.Utsunomiya, D.Koya, T.Babazono, T.Moriya, H.Makino, K.Kimura, Y.Suzuki, T.Wada, S.Ogawa, M.Inaba, Y.Kanno, T.Shigematsu, I.Masakane, K.Tsuchiya, K.Honda, K.Ichikawa, K.Shide, Journal of Diabetes Investigation, 6:242-246, Mar. 2015
• The biological significance of angiotensin-converting enzyme inhibition to combat kidney fibrosis, T.Nagai, K.Nitta, M.Kanasaki, D.Koya, K.Kanasaki, Clinical and Experimental Nephrology, 19:65-74, Feb. 2015
• A new classification of diabetic nephropathy 2014: a report from joint committee on diabetic nephropathy, (M.Haneda), K.Utsunomiya, D.Koya, T.Babazono, T.Moriya, H.Makino, K.Kimura, Y.Suzuki, T.Wada, S.Ogawa, M.Inaba, Y.Kanno, T.Shigematsu, I.Masakane, K.Tsuchiya, K.Honda, K.Ichikawa, K.Shide, Clinical and Experimental Nephrology, 19:1-5, Feb. 2015
• Pituitary apoplexy following gonadotropin-releasing hormone agonist administration with gonadotropin-secreting pituitary adenoma, Y.Sasagawa, O.Tachibana, A.Nakagawa, D.Koya, H.Iizuka, Journal of Clinical Neuroscience, 22:601-603, 2015
• A new classification of diabetic nephropathy 2014: a report from joint committee on diabetic nephropathy, (M.Haneda), K.Utsunomiya, D.Koya, T.Babazono, T.Moriya, H.Makino, K.Kimura, Y.Suzuki, T.Wada, S.Ogawa, M.Inaba, Y.Kanno, T.Shigematsu, I.Masakane, K.Tsuchiya, K.Honda, K.Ichikawa, K.Shide, Diabetology International, 5:207-211, Dec. 2014
• Low-protein diet for diabetic nephropathy, T.Otoda, K.Kanasaki, D.Koya, Current diabetes reports., 14:523;1-10, Sep. 2014
• Lipid mediators in diabetic nephropathy, SP.Srivastava, S.Shi, D.Koya, K.Kanasaki, Fibrogenesis & tissue repair [electronic resource], 7:1-10, Sep. 2014
• Role of nutrient-sensing signals in the pathogenesis of diabetic nephropathy, (S.Kume), D.Koya, T.Uzu, H.Maegawa, BioMed research international [electronic resource], 2014:315494;1-9, Jun. 2014
• Predictive properties of plasma amino acid profile for cardiovascular disease in patients with type 2 diabetes, (S.Kume), S.Araki, N.Ono, A.Shinhara, T.Muramatsu, H.Araki, K.Isshiki, K.Nakamura, H.Miyano, D.Koya, M.Haneda, S.Ugi, H.Kawai, A.Kashiwagi, T.Uzu, H.Maegawa, PloS one, 9:e101219;1-7, Jun. 2014
• Linagliptin-mediated DPP-4 inhibition ameliorates kidney fibrosis in streptozotocin-induced diabetic mice by inhibiting endothelial-to-mesenchymal transition in a therapeutic regimen, K.Kanasaki, S.Shi, M.Kanasaki, J.He, T.Nagai, Y.Nakamura, Y.Ishigaki, M.Kitada, SP.Srivastava, D.Koya, Diabetes., 63:2120-2131, Jun. 2014
• Fatty acids are novel nutrient factors to regulate mTORC1 lysosomal localization and apoptosis in podocytes, (M.Yasuda), Y.Tanaka, S.Kume, Y.Morita, M.Chin-Kanasaki, H.Araki, K.Isshiki, S.Araki, D.Koya, M.Haneda, A.Kashiwagi, H.Maegawa, T.Uzu, Biochimica et Biophysica Acta Molecular Basis of Disease, 1842:1097-1108, Jun. 2014
• Clinical therapeutic strategies for early stage of diabetic kidney disease, M.Kitada, K.Kanasaki, D.Koya, World journal of diabetes [electronic resource], 5:342-356, Jun. 2014
• Evidence-based clinical practice guideline for CKD 2013, (Japanese Society of Nephrology), K.Kanasaki, M.Kitada, D.Koya, Clinical and experimental nephrology, 18:346-423, May. 2014
• Cancer biology in diabetes, S.Shi, Y.He, D.Koya, K.Kanasaki, Journal of diabetes investigation, 5:251-264, May. 2014
• N-acetyl-seryl-asparatyl-lysyl-proline: a valuable endogenous anti-fibrotic peptide for combating kidney fibrosis in diabetes, K.Kanasaki, T.Nagai, K.Nitta, M.Kitada, D.Koya, Frontiers in pharmacology [electronic resource], 5:1-11, Apr. 2014
• Interventions against nutrient-sensing pathways represent an emerging new therapeutic approach for diabetic nephropathy, D.Koya, M.Kitada, S.Kume, K.Kanasaki, Clinical and experimental nephrology, 18:210-213, Apr. 2014
• N-acetyl-seryl-aspartyl-lysyl-proline inhibits diabetes-associated kidney fibrosis and endothelial-mesenchymal transition, T.Nagai, M.Kanasaki, SP.Srivastava, Y.Nakamura, Y.Ishigaki, M.Kitada, S.Shi, K.Kanasaki, D.Koya, BioMed research international [electronic resource], 2014:696475;1-12, Mar. 2014
• Dual protein kinase C alpha and beta inhibitors and diabetic kidney disease: a revisited therapeutic target for future clinical trials, D.Koya, Journal of diabetes investigation, 5:147-148, Mar. 2014
• Role of sirtuins in kidney disease, M.Kitada, S.Kume, D.Koya, Current opinion in nephrology and hypertension., 23:75-79, Jan. 2014
• Autophagy: emerging therapeutic target for diabetic nephropathy, (S.Kume), K.Yamahara, M.Yasuda, H.Maegawa, D.Koya, Seminars in nephrology., 34:9-16, Jan. 2014
• Eplerenone ameliorates the phenotypes of metabolic syndrome with NASH in liver-specific SREBP-1c Tg mice fed high-fat and high-fructose diet., (T.Wada), Y.Miyashita, M.Sasaki, Y.Aruga, Y.Nakamura, Y.Ishii, M.Sasahara, K.Kanasaki, M.Kitada, D.Koya, H.Shimano, H.Tsuneki, T.Sasaoka, American journal of physiology. Endocrinology and metabolism., 305:E1415-E1425, Dec. 2013
• The biological consequence of obesity on the kidney., K.Kanasaki, M.Kitada, M.Kanasaki, D.Koya, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association., 28suppl 4;1-7, Nov. 2013
• SIRT1 in type 2 diabetes: mechanisms and therapeutic potential., M.Kitada, D.Koya, Diabetes & metabolism journal., 37:315-325, Nov. 2013
• Renal protective effects of resveratrol., M.Kitada, D.Koya, Oxidative medicine and cellular longevity, 2013:568093;1-7, Nov. 2013
• Obesity-mediated autophagy insufficiency exacerbates proteinuria-induced tubulointerstitial lesions., (K.Yamahara), S.Kume, D.Koya, Y.Tanaka, Y.Morita, M.Chin-Kanasaki, H.Araki, K.Isshiki, S.Araki, M.Haneda, T.Matsusaka, A.Kashiwagi, H.Maegawa, T.Uzu, Journal of the American Society of Nephrology : JASN., 24:1769-1781, Nov. 2013
• Ketogenic essential amino acids replacement diet ameliorated hepatosteatosis with altering autophagy-associated molecules., L.Xu, M.Kanasaki, J.He, M.Kitada, K.Nagao, H.Jinzu, Y.Noguchi, H.Maegawa, K.Kanasaki, D.Koya, Biochimica et biophysica acta., 1832:1605-1612, Oct. 2013
• Calorie restriction in overweight males ameliorates obesity-related metabolic alterations and cellular adaptations through anti-aging effects, possibly including AMPK and SIRT1 activation., M.Kitada, S.Kume, A.Takeda-Watanabe, S.Tsuda, K.Kanasaki, D.Koya, Biochimica et biophysica acta., 1830:4820-4827, Oct. 2013
• Role of the endothelial-to-mesenchymal transition in renal fibrosis of chronic kidney disease., J.He, Y.Xu, D.Koya, K.Kanasaki, Clinical and experimental nephrology, 17:488-497, Aug. 2013
• MicroRNAs in kidney fibrosis and diabetic nephropathy: roles on EMT and EndMT., SP.Srivastava, D.Koya, K.Kanasaki, BioMed research international [electronic resource], 2013:125469;1-10, Aug. 2013
• Intraportal GLP-1 stimulates insulin secretion predominantly through the hepatoportal-pancreatic vagal reflex pathways., M.Nishizawa, H.Nakabayashi, K.Uehara, A.Nakagawa, K.Uchida, D.Koya, American journal of physiology. Endocrinology and metabolism., 305:E376-E387, Aug. 2013
• Guidelines on the use of iodinated contrast media in patients with kidney disease 2012 -digest version- JSN, JRS and JCS Joint Working Group, (I.Ohno), H.Hayashi, K.Aonuma, M.Horio, N.Kashihara, H.Okada, Y.Komatsu, S.Tamura, K.Awai, Y.Yamashita, R.Kuwatsuru, A.Hirayama, Y.Saito, T.Murohara, N.Tamaki, A.Sato, T.Takayama, E.Imai, Y.Yasuda, D.Koya, Y.Tsubakihara, S.Horie, Y.Korogi, Y.Narumi, K.Hayakawa, H.Daida, K.Node, I.Kubota, Clinical and experimental nephrology, 17:441-479, Jul. 2013
• Guidelines on the use of iodinated contrast media in patients with kidney disease 2012 -digest version- JSN, JRS and JCS Joint Working Group, (I.Ohno), H.Hayashi, K.Aonuma, M.Horio, N.Kashihara, H.Okada, Y.Komatsu, S.Tamura, K.Awai, Y.Yamashita, R.Kuwatsuru, A.Hirayama, Y.Saito, T.Murohara, N.Tamaki, A.Sato, T.Takayama, E.Imai, Y.Yasuda, D.Koya, Y.Tsubakihara, S.Horie, Y.Korogi, Y.Narumi, K.Hayakawa, H.Daida, K.Node, I.Kubota, Japanese journal of radiology, 31:546-584, Jul. 2013
• Guidelines on the use of iodinated contrast media in patients with kidney disease 2012 -digest version- JSN, JRS and JCS Joint Working Group, (I.Ohno), H.Hayashi, K.Aonuma, M.Horio, N.Kashihara, H.Okada, Y.Komatsu, S.Tamura, K.Awai, Y.Yamashita, R.Kuwatsuru, A.Hirayama, Y.Saito, T.Murohara, N.Tamaki, A.Sato, T.Takayama, E.Imai, Y.Yasuda, D.Koya, Y.Tsubakihara, S.Horie, Y.Korogi, Y.Narumi, K.Hayakawa, H.Daida, K.Node, I.Kubota, Circulation journal : official journal of the Japanese Circulation Society, 77:1883-1914, Jul. 2013
• Cilostazol attenuates spontaneous microaggregation of platelets in type 2 diabetic patients with insufficient platelet response to aspirin., (S.Araki), H.Matsuno, M.Haneda, D.Koya, Y.Kanno, S.Kume, K.Isshiki, H.Araki, S.Ugi, H.Kawai, A.Kashiwagi, T.Uzu, H.Maegawa, Diabetes Care., 36:e92-e93, Jul. 2013
• Three ileus cases associated with the use of dipeptidyl peptidase-4 inhibitors in diabetic patients., K.Kanasaki, K.Konishi, R.Hayashi, H.Shiroeda, T.Nomura, A.Nakagawa, T.Nagai, A.Takeda-Watanabe, H.Ito, S.Tsuda, M.Kitada, M.Fujii, M.Kanasaki, M.Nishizawa, Y.Nakano, Y.Tomita, N.Ueda, T.Kosaka, D.Koya, Journal of diabetes investigation, 4:673-675, May. 2013
• Predictive effects of urinary liver-type fatty acid-binding protein for deteriorating renal function and incidence of cardiovascular disease in type 2 diabetic patients without advanced nephropathy., (S.Araki), M.Haneda, D.Koya, T.Sugaya, K.Isshiki, S.Kume, A.Kashiwagi, T.Uzu, H.Maegawa, Diabetes Care., 36:1248-1253, May. 2013
• Altered unfolded protein response is implicated in the age-related exacerbation of proteinuria-induced proximal tubular cell damage., (N.Takeda), S.Kume, Y.Tanaka, Y.Morita, M.Chin-Kanasaki, H.Araki, K.Isshiki, S.Araki, M.Haneda, D.Koya, A.Kashiwagi, H.Maegawa, T.Uzu, The American journal of pathology., 183:774-785, May. 2013
• The administration of pitavastatin augments creatinine clearance associated with reduction in oxidative stress parameters: acute and early effects., (H.Kakuda), K.Kanasaki, D.Koya, N.Takekoshi, Clinical and experimental nephrology, 17:240-247, Apr. 2013
• Effects of atorvastatin on renal function in patients with dyslipidemia and chronic kidney disease: rationale and design of the assessment of clinical usefulness in CKD patients with atorvastatin (ASUCA) trial., (K.Ueshima), M.Kasahara, D.Koya, T.Babazono, T.Sato, M.Imamoto, S.Yasuno, A.Fujimoto, S.Tanaka, G.Kimura, K.Nakao, Clinical and experimental nephrology, 17:211-217, Apr. 2013
• Sirtuins and renal diseases: relationship with aging and diabetic nephropathy., M.Kitada, S.Kume, A.Takeda-Watanabe, K.Kanasaki, D.Koya, Clinical science, 124:153-164, Feb. 2013
• Japan Diabetic Nephropathy Cohort Study: study design, methods, and implementation., (K.Furuichi), M.Shimizu, T.Toyama, D.Koya, Y.Koshino, H.Abe, K.Mori, H.Satoh, M.Imanishi, M.Iwano, H.Yamauchi, E.Kusano, S.Fujimoto, Y.Suzuki, S.Okuda, K.Kitagawa, Y.Iwata, S.Kaneko, S.Nishi, H.Yokoyama, Y.Ueda, M.Haneda, H.Makino, T.Wada, Clinical and experimental nephrology, 17:819-826, Feb. 2013
• Diabetic nephropathy: the role of inflammation in fibroblast activation and kidney fibrosis., K.Kanasaki, G.Taduri, D.Koya, Frontiers in endocrinology [electronic resource], 4:1-15, Feb. 2013
• Anti-aging molecule, Sirt1: a novel therapeutic target for diabetic nephropathy., (S.Kume), M.Kitada, K.Kanasaki, H.Maegawa, D.Koya, Archives of pharmacal research., 36:230-236, Feb. 2013
• Sirtuins as possible drug targets in type 2 diabetes., M.Kitada, S.Kume, K.Kanasaki, A.Takeda-Watanabe, D.Koya, Current drug targets, 14:622-636, Jan. 2013
• The role of autophagy in the pathogenesis of diabetic nephropathy., (K.Yamahara), M.Yasuda, S.Kume, D.Koya, H.Maegawa, T.Uzu, Journal of diabetes research., 2013:193757;1-9, 2013
• Autophagy: a novel therapeutic target for kidney diseases, (S.Kume), T.Uzu, H.Maegawa, D.Koya, Clinical and experimental nephrology, 16:827-832, Dec. 2012
• Autophagy as a therapeutic target in diabetic nephropathy., (Tanaka Y), Kume S, Kitada M, Koya D, Exp Diabetes Res, 2012;2012:628978. Epub 2011 Oct 19., Jan. 2012
• Elevation of the antifibrotic peptide N-acetyl-seryl-aspartyl-lysyl-proline: a blood pressure-independent beneficial effect of angiotensin I-converting enzyme inhibitors, M.Kanasaki, T.Nagai, M.Kitada, D.Koya, K.Kanasaki, Fibrogenesis & tissue repair [electronic resource], 4:25;1-12, Dec. 2011
• Elevated serum levels of interleukin-18 in patients with overt diabetic nephropathy: effects of miglitol, (T.Uzu), H.Yokoyama, H.Ito, D.Koya, A.Nakagawa, M.Nishizawa, H.Maegawa, Y.Yokomaku, S.Araki, A.Abiko, M.Haneda, Clinical and experimental nephrology, 15:58-63, Dec. 2011
• SIRT3 attenuates palmitate-induced ROS production and inflammation in proximal tubular cells., (T.Koyama), S.Kume, D.Koya, S.Araki, K.Isshiki, M.Chin-Kanasaki, T.Sugimoto, M.Haneda, T.Sugaya, A.Kashiwagi, H.Maegawa, T.Uzu, Free radical biology & medicine, 51:1258-67, Sep. 2011
• Reversal of redox-dependednt inhibition of diacylglycerol kinase by antioxidants in mesangial cells exposed to high glucose, H.Astumi, M.Kitada, K.Kanasaki, D.Koya, Molecular medicine reports., 4:923-927, Sep. 2011
• Dietary restriction ameliorates diabetic nephropathy through anti-inflammatory effects and regulation of the autophagy via restoration of Sirt1 in diabetic Wistar fatty (fa/fa) rats: a model of type 2 diabetes, M.Kitada, A.Takeda, T.Nagai, H.Ito, K.Kanasaki, D.Koya, Experimental diabetes research [electronic resource], 2011/908185;1-11, Sep. 2011
• Rapid effects of pitavastatin on uric acid homeostasis., (H.Kakuda), D.Koya, N.Takekoshi, 35:39-47, Jul. 2011
• Reversal of redox-dependent inhibition of diacylglycerol kinase by antioxidants in mesangial cells exposed to high glucose., Hisanari Atsumi, Munehiro Kitada, Keizo Kanasaki, Daisuke Koya, Molecular Medicine Reports, 4:923-927, Jul. 2011
• Food intake－suppressing action of incretin and anti－obesity therapy, A.Nakagawa, M.Nishizawa, D.Koya, 69:826-830, May. 2011
• Resveratrol improves oxidative stress and protects against diabetic nephropathy through normalization of Mn-SOD dysfunction in AMPK/SIRT1-independent pathway., Munehiro Kitada, Daisuke Koya, Shinji Kume, Diabetes., 60(2):634-43, Feb. 2011
• Resveratrol improves oxidative stress and protects against diabetic nephropathy through normalization of Mn-SOD dysfunction in AMPK/SIRT1-independent pathway, M.Kitada, S.Kume, N.Imaizumi, D.Koya, Diabetes., 60:634-643, Feb. 2011
• Food intake-suppressing action of incretin and anti-obesity therapy, A.Nakagawa, M.Nishizawa, D.Koya, 69:826-830, 2011
• Therapeutic management of diabetic kidney disease, D.Koya, S.Araki, M.Haneda, Journal of diabetes investigation, 2:248-254, 2011
• Low-Frequency Electroacupuncture Improves Insulin Sensitivity in Obese Diabetic Mice through Activation of SIRT1/PGC-1α in Skeletal Muscle, F.Liang, R.Chen, A.Nakagawa, M.Nishizawa, S.Tsuda, H.Wang, D.Koya, Evidence-based complementary and alternative medicine : eCAM., 2011/197636;1-9, 2011
• Dietary restriction ameliorates diabetic nephropathy through anti-inflammatory effects and regulation of the autophagy via restoration of Sirt1 in Diabetic Wistar fatty (fa/fa) rats, a model of type 2 diabetes., Munehiro Kitada, Ai Takeda, Takako Nagai, Keizo Kanasaki, Daisuke Koya, Experimental Diabetes Research, in press, 2011
• Biology of obesity: lessons from animal models of obesity, K.Kanasaki, D.Koya, Journal of biomedicine & biotechnology, 2011/735297;1-11, 2011
• Association between single nucleotide polymorphisms within genes encoding sirtuin families and diabetic nephropathy in Japanese subjects with type 2 diabetes, (S.Maeda), D.Koya, S.Araki, T.Babazono, T.Umezono, M.Toyoda, K.Kawai, M.Imanishi, T.Uzu, D.Suzuki, H.Maegawa, A.Kashiwagi, Y.Iwamoto, Y.Nakamura, Clinical and experimental nephrology, 15:381-390, 2011
• Efficacy and tolerability of vildagliptin as an add-on to glimepiride in Japanese patients with type 2 diabetes mellitus, (M.Kikuchi), M.Haneda, D.Koya, K.Tobe, Y.Onishi, A.Couturier, N.Mimori, Y.Inaba, M.Goodman, Diabetes research and clinical practice., 89:216-223, Sep. 2010
• Dietary restriction: standing up for sirtuins, (J.A.Baur), D.Chen, E.N.Chini, K.Chua, H.Y.Cohen, R.de Cabo, C.Deng, S.Dimmeler, D.Gius, L.P.Guarente, S.L.Helfand, S.Imai, H.Itoh, T.Kadowaki, D.Koya, C.Leeuwenburgh, M.Mcburney, Y.Nabeshima, C.Neri, P.Oberdoerffer, R.G.Pestell, B.Rogina, J.Sadoshima, V.Sartorelli, M.Serrano, D.A.Sinclair, C.Steegborn, M.Tatar, H.A.Tissenbaum, Q.Tong, Science, 329:1012-1013, Aug. 2010
• Association between urinary type IV collagen level and deterioration of renal function in type 2 diabetic patients without overt proteinuia, (S.Araki), M.Haneda, D.Koya, K.Isshiki, S.Kume, T.Sugimoto, H.Kawai, Y.Nishio, A.Kashiwagi, T.Uzu, H.Maegawa, Diabetes Care., 33:1805-1810, Aug. 2010
• Acupuncture:is it effective for treatment of insulin resistance?, F.Liang, D.Koya, Diabetes, obesity & metabolism, 12:555-569, Jul. 2010
• SIRT1, a calorie restriction mimetic, in a new therapeutic approach for type 2 diabetes mellitus and diabetic vascular complications, (S.Kume), T.Uzu, A.Kashiwagi, D.Koya, Endocrine, metabolic & immune disorders drug targets, 10:16-24, Apr. 2010
• Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney, (S.Kume), T.Uzu, K.Horiike, M.C.Kanasaki, K.Isshiki, S.Araki, T.Sugimoto, M.Haneda, A.Kashiwagi, D.Koya, The Journal of clinical investigation, 120:1043-1055, Apr. 2010
• Long-term effect of modification of dietary protein intake on the progerssion of diabetic nephropathy: a randomised controlled trial, D.Koya, M.Haneda, S.Inomata, Y.Suzuki, D.Suzuki, H.Makino, K.Shikata, Y.Murakami, Y.Tomino, K.Yamada, S.I.Araki, A.Kashiwagi, R.Kikkawa, Diabetologia, 52:2037-2045, Aug. 2009
• Carotid atherosclerosis mediated by visceral adiposity and adipocytokines in type 2 diabetic subjects, K.Konishi, S.Nakano, H.Seto, S.Tsuda, D.Koya, Diabetes research and clinical practice., 85:171-178, Apr. 2009
• Exendin-4 has an anti-hypertensive effect in salt-sensitive mice model, (K.Hirata), S.Kume, S.Araki, M.Sakaguchi, M.Chin-Kanasaki, K.Isshiki, T.Sugimoto, A.Nishiyama, D.Koya, M.Haneda, A.Kashiwagi, T.Uzu, Biochemical and biophysical research communications, 380:44-49, Feb. 2009
• Structural and functional changes in the kidneys of high-fat diet-induced obese mice, (N.Deji), S.Kume, S.Araki, M.Soumura, T.Sugimoto, K.Isshiki, M.Chin-Kanasaki, M.Sakaguchi, D.Koya, M.Haneda, A.Kashiwagi, T.Uzu, American journal of physiology. Renal physiology, 296:F118-F126, Jan. 2009
• Clinical impact of reducing microalbuminuria in patients with type 2 diabetes mellitus, (S.Araki), M.Haneda, D.Koya, A.Kashiwagi, T.Uzu, R.Kikkawa, Diabetes research and clinical practice., 82(Suppl.1):S54-S58, Nov. 2008
• AST-120 (Kremezin) initiated in early stage chronic kidney disease stunts the progression of renal dysfunction in type 2 diabetic subjects, K.Konishi, S.Nakano, S.Tsuda, A.Nakagawa, T.Kigoshi, D.Koya, Diabetes research and clinical practice., 81:310-315, Sep. 2008
• Impact of renin-angiotensin system inhibition on microalbuminuria in type 2 diabetes: a post hoc analysis of the Shiga Microalbuminuria Reduction Trial (SMART), (The Shiga microalbuminuria reduction trial (SMART) group), S.Nakano, D.Koya, Hypertension research : official journal of the Japanese Society of Hypertension., 31:1171-1176, Aug. 2008
• A lack of increase in high molecular weight-adiponectin in macroalbuminuric subjects with metabolic syndrome may exert renal and atherosclerotic risks, S.Tsuda, S.Nakano, K.Konishi, D.Koya, Diabetes research and clinical practice., 79:503-509, Mar. 2008
• Asialoerythropoietin prevents contrast-induced nephropathy, (Y.Yokomaku), T.Sugimoto, S.Kume, S.Araki, K.Isshiki, M.Chin-Kanasaki, M.Sakaguchi, N.Nitta, M.Haneda, D.Koya, T.Uzu, A.Kashiwagi, Journal of the American Society of Nephrology : JASN., 19:321-328, Feb. 2008
• Reduction in microalbuminuria as an integrated indicator for renal and cardiovascular risk reduction in patients with type 2 diabetes, (S.Araki), M.Haneda, D.Koya, H.Hidaka, T.Sugimoto, M.Isono, K.Isshiki, M.Chin-Kanasaki, T.Uzu, A.Kashiwagi, Diabetes., 56:1727-1730, May. 2007
• Legumain/asparaginyl endopeptidase controls extracellular matrix remodeling through the degradation of fibronectin in mouse renal proximal tubular cells, (Y.Morita), H.Araki, T.Sugimoto, K.Takeuchi, T.Yamane, T.Maeda, Y.Yamamoto, K.Nishi, M.Asano, K.Shirahama-Noda, M.Nishimura, T.Uzu, I.Hara-Nishimura, D.Koya, A.Kashiwagi, I.Ohkubo, FEBS letters, 581:1417-1424, 2007
• Glucocorticoid-induced diabetes mellitus: prevalence and risk factors in primary renal diseases, (T.Uzu), T.Harada, M.Sakaguchi, M.Kanasaki, K.Isshiki, S.Araki, T.Sugiomoto, D.Koya, M.Haneda, A.Kashiwagi, A.Kashiwagi, A.Yamauchi, Nephron. Clinical practice, 105:c54-c57, Nov. 2006
• Polymorphisms of the protein kinase C-β gene (PRKCB1) accelerate kidney disease in type 2 diabetes without overt proteinuria, (S.Araki), M.Haneda, T.Sugimoto, M.Isono, K.Isshiki, A.Kashiwagi, D.Koya, Diabetes Care., 29:864-868, Apr. 2006
• N-acetyl-seryl-aspartyl-lysyl-proline inhibits DNA synthesis in human mesangial cells via up-regulation of cell cycle modulators, (K.Kanasaki), M.Haneda, T.Sugimoto, K.Shibuya, M.Isono, K.Isshiki, S.Araki, T.Uzu, A.Kashiwagi, D.Koya, Biochemical and biophysical research communications, 342:758-765, Apr. 2006
• Effect of protein kinase Cβ inhibitor on Ca2+ homeostasis in diabetic sensory neurons, (M.Tahara), M.Omatsu-Kanbe, M.Sanada, K.Maeda, D.Koya, H.Matsuura, A.Kashiwagi, H.Yasuda, Neuroreport., 17:683-688, Apr. 2006
• N-acetyl-seryl-aspartyl-lysyl-proline ameliorates the progression of renal dysfunction and fibrosis in WKY rats with established anti-glomerular basement membrane nephritis, (M.Omata), H.Taniguchi, D.Koya, K.Kanasaki, R.Sho, Y.Kato, R.Kojima, M.Haneda, N.Inomata, Journal of the American Society of Nephrology : JASN., 17:674-685, Feb. 2006
• Inhibition of mTOR signaling with rapamycin attenuates renal hypertrophy in the early diabetic mice, (M.Sakaguchi), M.Isono, K.Isshiki, T.Sugimoto, D.Koya, A.Kashiwagi, Biochemical and biophysical research communications, 340:296-301, Feb. 2006
• Translocation of glomerular p47phox and p67phox by protein kinase C-beta activation is required for oxidative stress in diabetic nephropathy., Munehiro Kitada, Daiske Koya, Diabetes., 52(10):2603-14, Oct. 2003
• A Low-Protein Diet for Diabetic Kidney Disease: Its Effect and Molecular Mechanism, an Approach from Animal Studies, Munehiro.Kitada, Yoshio.Ogura, Itaru.Monno, Daisuke.Koya, Nutrients, 10:10(5). pii: E544. doi: 10.3390/nu10050544., Apr. 2018
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• How Should We Think About Diabetic Kidney Disease in the Current Clinical Setting?, Munehiro.Kitada, Daisuke.Koya, Journal of the Japan Diabetes Society, 61:520-523, Aug. 2018
  DOI:10.11213/tonyobyo.61.520
• Renal mitochondrial oxidative stress is enhanced by the reduction of Sirt3 activity, in Zucker diabetic fatty rats, Yoshio.Ogura, Munehiro.Kitada, Itaru.Monno, Keizo,Kanasaki, Ai.Watanabe, Daisuke.Koya, Redox Report, 23:153-159, Dec. 2018
  DOI:10.1080/13510002.2018.1487174
• FGFR1 is essential for N-acetyl-seryl-aspartyl-lysyl-proline regulation of mitochondrial dynamics by upregulating microRNA let-7b-5p, Qiongying.Hu, Jinpeng.Li, Kyoko.Nitta, Munehiro.Kitada, Takako.Nagai, Keizo.Kanasaki, Daisuke.Koya, Biochemical and Biophysical Research Communications, 495:2214-2220, Jan. 2018
  DOI:10.1016/j.bbrc.2017.12.089
• A low-protein diet exerts a beneficial effect on diabetic status and prevents diabetic nephropathy in Wistar fatty rats, an animal model of type 2 diabetes and obesity, Munehiro.Kitada, Yoshio.Ogura, Taeko.Suzuki, Itaru.Monno, Keizo.Kanasaki, Ai.Watanabe, Daisuke.Koya, Nutrition & Metabolism, 15:15:20.doi: 10.1186/s12986-018-0255-1. eCollection 2108., Mar. 2018
  DOI:10.1186/s12986-018-0255-1
• Severe electrolytes disorders with the interstitial kidney alterations in the patient with the history of total thyroidectomy and parathyroidectomy: possible role of vitamin D deficiency, Emi.Kawakita, Keizo.Kanasaki, Taro.Hirai, Shin-ichi.Tsuda, Ai.Watanabe, Kyoko.Nitta, Munehiro.Kitada, Yoshio.Ogura, Yuta.Takagaki, Mizue.Fujii, Takako.Nagai, Keiji.Shimada, Susumu.Takagi, Yuiko.Mizunuma, Itaru.Monno, Shino.Fujimoto, Hiroshi.Minato, Nobuhiko.Miyatake, Atsushi.Nakagawa, Daisuke.Koya, Clinical Case Reports, 6:983-989, Apr. 2018
  DOI:10.1002/ccr3.1500
• A ketogenic amino acid rich diet benefits mitochondrial homeostasis by altering the AKT/4EBP1 and autophagy signaling pathways in the gastrocnemius and soleus, Jinpeng.Li, Megumi.Kanasaki, Ling.Xu , Munehiro.Kitada, Kenji.Nagao, Yusuke.Adachi, Hiroko.Jinzu, Yasushi.Noguchi, Miyuki.Kohno, Keizo.Kanasaki, Daisuke.Koya, Biochimica et Biophysica Acta-General Subjects, 1862:1547-1555, Jul. 2018
  DOI:10.1016/j.bbagen.2018.03.013
• Ipragliflozin improves mitochondrial abnormalities in renal tubules induced by a high-fat diet, Susumu.Takagi, Jinpeng.Li, Yuta.Takagaki, Munehiro.Kitada, Kyoko.Nitta, Toshiyuki.Takasu, Keizo.Kanasaki, Daisuke.Koya, Journal of Diabetes Investigation, 9:1025-1032, Sep. 2018
  DOI:10.1111/jdi.12802
• AMP-Activated Protein (AMPK) in pathophysiology of Pregnancy Complications, Asako.Kumagai, Atsuo.Itakura, Daisuke.Koya, Keizo.Kanasaki, International journal of molecular sciences, 19:19(10). Pii: E3076; doi:10.3390/ijms19103076., Oct. 2018
  DOI:10.3390/ijms19103076
• The Japanese clinical practice guideline for acute kidney injury 2016., (Kent.Doi), Osamu.Nishida, Takashi.Shigematsu, Tomohito.Sadahiro, Noritomo.Itami, Kunitoshi.Iseki, Yukio.Yuzawa, Hirokazu.Okada, Daisuke.Koya, Hideyasu.Kiyomoto, Yugo.Shibagaki, Kenichi.Matsuda, Akihiko.Kato, Terumasa.Hayashi, Tomonari.Ogawa, Tatsuo.Tsukamoto, Eisei.Noiri, Shigeo.Negi, Koichi.Kamei, Hirotsugu.Kitayama, Naoki.Kashihara, Toshiki.Moriyama, Yoshio.Terada, The Japanese Clinical Practice Guideline for Acute Kidney Injury 2016 Committee, Clinical and Experimental Nephrology, 22:985-1045, Oct. 2018
  DOI:10.1007/s10157-018-1600-4
• The Japanese clinical practice guideline for acute kidney injury 2016, (Kent.Doi), Osamu.Nishida, Takashi.Shigematsu, Tomohito.Sadahiro, Noritomo.Itami, Kunitoshi.Iseki, Yukio.Yuzawa, Hirokazu.Okada, Daisuke.Koya, Hideyasu.Kiyomoto, Yugo.Shibagaki, Kenichi.Matsuda, Akihiko.Kato, Terumasa.Hayashi, Tomonari.Ogawa, Tatsuo.Tsukamoto, Eisei.Noiri, Shigeo.Negi, Koichi.Kamei, Hirotsugu.Kitayama, Naoki.Kashihara, Toshiki.Moriyama, Yoshio.Terada, The Japanese Clinical Practice Guideline for Acute Kidney Injury 2016 Committee, Journal of Intensive Care Medicine, 6:6:48.doi:10.1186/s40560-018-0308-6. eCollection 2018., Aug. 2018
  DOI:10.1186/s40560-018-0308-6
• SIRT3 deficiency leads to induction of abnormal glycolysis in diabetic kidney with fibrosis, Swayam Prakash.Sirvastava, Jinpeng.Li, Munehiro.Kitada, Hiroki.Fujita, Yuichiro.Yamada, Julie E. Goodwin, Keizo.Kanasaki, Daisuke.Koya, Cell Death & Disease, 9:doi:10.1038/s41419-018-1057-0, Sep. 2018
  DOI:10.1038/s41419-018-1057-0
• Decline in estimated glomerular filtration rate is associated with risk of end-stage renal disease in type 2 diabetes with macroalbuminuria: an observational study from JDNCS, (Miho.Shimizu), Kengo.Furuichi, Tadashi.Toyama, Tomoaki.Funamoto, Shinji.Kitajima, Akinori.Hara, Daisuke.Ogawa, Daisuke.Koya, Kenzo.Ikeda, Yoshitaka.Koshino, Yukie.Kurokawa, Hideharu.Abe, Kiyoshi.Mori, Masaaki.Nakayama, Yoshio.Konishi, Ken-ichi.Samejima, Masaru.Matsui, Hiroyuki.Yamauchi, Tomohito.Gohda, Kei.Fukami, Daisuke.Nagata, Hidenori.Yamazaki, Yukio.Yuzawa, Yoshiki.Suzuki, Shouichi.Fujimoto, Shoichi.Maruyama, Sawako.Kato, Takero.Naito, Kenichi.Yoshimura, Hitoshi.Yokoyama, Takashi.Wada, Research Group of Diabetic Nephropathy, The Ministry of Health, Labour, and Welfare of Japan and Japan Agency for Medical Research and Development, Clinical and Experimental Nephrology, 22:377-387, Apr. 2018
• Sirtuins and Type 2 Diabetes: Role in Inflammation, Oxidative Stress, and Mitochondrial Function, Kitada Munehiro, Ogura Yoshio, Monno Itaru, Koya Daisuke, Frontiers in Endocrinology, 10:187, Mar. 2019
  DOI:10.3389/fendo.2019.00187
• Diabetic kidney disease: Its current trends and future therapeutic perspectives, Daisuke Koya, JOURNAL OF DIABETES INVESTIGATION, 10:1174-1176, Sep. 2019
  DOI:10.1111/jdi.13121
• N-Acetyl-seryl-aspartyl-lysyl-proline is a potential biomarker of renal function in normoalbuminuric diabetic patients with eGFR ≥ 30 ml/min/1.73 m2, Nitta Kyoko, Nagai Takako, Mizunuma Yuiko, Kitada Munehiro, Nakagawa Atsushi, Sakurai Masaru, Toyoda Masao, Haneda Masakazu, Kanasaki Keizo, Koya Daisuke, Clinical and Experimental Nephrology, 23:1004-1012, Aug. 2019
  DOI:10.1007/s10157-019-01733-6
• Identification of subgroups of patients with type 2 diabetes with differences in renal function preservation, comparing patients receiving sodium-glucose co-transporter-2 inhibitors with those receiving dipeptidyl peptidase-4 inhibitors, using a supervised machine-learning algorithm (PROFILE study): A retrospective analysis of a Japanese commercial medical database, (Zhou Fang L), Watada Hirotaka, Tajima Yuki, Berthelot Mathilde, Kang Dian, Esnault Cyril, Shuto Yujin, Maegawa Hiroshi, Koya Daisuke, Diabetes, obesity & metabolism, 21:1925-1934, Aug. 2019
  DOI:10.1111/dom.13753
• Secular changes in clinical manifestations of kidney disease among Japanese adults with type 2 diabetes from 1996 to 2014, (Kume Shinji), Araki Shin-ichi, Ugi Satoshi, Morino Katsutaro, Koya Daisuke, Nishio Yoshihiko, Haneda Masakazu, Kashiwagi Atsunori, Maegawa Hiroshi, Journal of Diabetes Investigation, 10:1032-1040, Jul. 2019
  DOI:10.1111/jdi.12977
• Proposal of classification of "chronic kidney disease (CKD) with diabetes" in clinical setting, Kitada Munehiro, Koya Daisuke, Diabetology international, 10:180-182, Jul. 2019
  DOI:10.1007/s13340-019-00396-8
• Relevance of Autophagy Induction by Gastrointestinal Hormones: Focus on the Incretin-Based Drug Target and Glucagon., Kanasaki Keizo, Kawakita Emi, Koya Daisuke, Frontiers in pharmacology, 10:476, May. 2019
  DOI:10.3389/fphar.2019.00476
• Dipeptidyl peptidase-4 plays a pathogenic role in BSA-induced kidney injury in diabetic mice, Takagaki Yuta, Shi Sen, Katoh Makoto, Kitada Munehiro, Kanasaki Keizo, Koya Daisuke, Scientific reports, 9:7519, May. 2019
  DOI:10.1038/s41598-019-43730-5
• The impact of dietary protein intake on longevity and metabolic health, Kitada Munehiro, Ogura Yoshio, Monno Itaru, Koya Daisuke, EBioMedicine, 43:632-640, May. 2019
  DOI:10.1016/j.ebiom.2019.04.005
• βklotho is essential for the anti-endothelial mesenchymal transition effects of N-acetyl-seryl-aspartyl-lysyl-proline, Gao Rongfen, Kanasaki Keizo, Li Jinpeng, Kitada Munehiro, Okazaki Toshiro, Koya Daisuke, FEBS open bio, 9:1029-1038, May. 2019
  DOI:10.1002/2211-5463.12638
• Effect of switching to teneligliptin from other dipeptidyl peptidase-4 inhibitors on glucose control and renoprotection in type 2 diabetes patients with diabetic kidney disease, Kitada Munehiro, Ogura Yoshio, Nitta Kyoko, Fujii Mizue, Kanasaki Keizo, Konishi Kazunori, Iida Yasuo, Nakagawa Atsushi, Koya Daisuke, Journal of diabetes investigation, 10:706-713, May. 2019
  DOI:10.1111/jdi.12917
• Inhibition of Dipeptidyl Peptidase-4 Accelerates Epithelial-Mesenchymal Transition and Breast Cancer Metastasis via the CXCL12/CXCR4/mTOR Axis, Yang Fan, Takagaki Yuta, Yoshitomi Yasuo, Ikeda Takayuki, Li Jinpeng, Kitada Munehiro, Kumagai Asako, Kawakita Emi, Shi Sen, Kanasaki Keizo, Koya Daisuke, Cancer research, 79:735-746, Feb. 2019
  DOI:10.1158/0008-5472.CAN-18-0620

Books etc

• Capter3 Patient assessment and diagnosis
  Managing diabetic nephropathies in clinical practice
  Daisuke.Koya
  Adis  2017