ISHIGAKI Yasuhito

FacultyDepartment of Life Sciences, Division of Systems Bioscience for Drug Discovery Based on Intrinsically Disordered Proteins, Research Support Center, Regenerative Medicine Center
PositionProfessor

Researcher Profile & Settings

Research

    Overview of research:
    Quality control of genetic information and gene expression.

Education

  • Kanazawa University Graduate School Division of Pharmaceutical Sciences
  • Kanazawa University Faculty of Pharmaceutical Science

Degree

  • Doctor of Pharmacy

Research Activities

Published Papers

  • Protective Effects of Peroxiredoxin 4 (PRDX4) on Cholestatic Liver Injury., Jing.Zhang, Xin.Guo, Taiji.Hamada, Seiya.Yokoyama, Yuka.Nakamura, Jianbo.Zheng, Nozomu.Kurose, Yasuhito.Ishigaki, Hideaki.Uramoto, Akihide.Tanimoto, Sohsuke.Yamada, Int J Mol Sci.19:pii: E2509Aug. 2018
  • Translational Control of Sox9 RNA by mTORC1 Contributes to Skeletogenesis, Takashi Iezaki, Tetsuhiro Horie, Kazuya Fukasawa, Makoto Kitabatake, Yuka Nakamura, Gyujin Park, Yuki Onishi, Kakeru Ozaki, Takashi Kanayama, Manami Hiraiwa, Yuka Kitaguchi, Katsuyuki Kaneda, Takayuki Manabe, Yasuhito Ishigaki, Mutsuhito Ohno, Eiichi Hinoi, Stem Cell Reports11:228-241Jul. 2018
  • Tropomyosin 2 heterozygous knockout in mice using CRISPR-Cas9 system displays the inhibition of injury-induced epithelial-mesenchymal transition, and lens opacity, Teppei Shibata, Shinsuke Shibata, Yasuhito Ishigaki, Etsuko Kiyokawa, Masahiko Ikawa, Dhirendra P. Singh, Hiroshi Sasaki, Eri Kubo, Mechanisms of Ageing and Development171:24-30Apr. 2018
  • Caspase-mediated cleavage of X-ray repair cross-complementing group 4 promotes apoptosis by enhancing nuclear translocation of caspase-activated DNase., Yumi.Sunatani, Radhika Pankaj Kamdar, Mukesh Kumar Sharma, Tadashi.Matsui, Ryo.Sakasai, Mitsumasa.Hashimoto, Yasuhito.Ishigaki, Yoshihisa.Matsumoto, Kuniyoshi.Iwabuchi, Experimental cell research362:450Jan. 2018
  • C-terminal short arginine/serine repeat sequence-dependent regulation of Y14(RBM8A) localization, Takanori.Tatsuno, Yasuhito.Ishigaki, SCIENTIFIC REPORTS8:612Jan. 2018
  • Upregulation of multiple signaling pathways by Dock5 deletion in epithelial cells, Xiaohe Xu, Hisayoshi Yoshizaki, Yasuhito Ishigaki, Eri Kubo, Hiroshi Minato, Etsuko Kiyokawa, Molecular Vision23:1081-1092Dec. 2017
  • Effect of Collagen Tripeptide on Atherosclerosis in Healthy Humans., N.Tomosugi, S.Yamamoto, M.Takeuchi, H.Yonekura, Y.Ishigaki, N.Numata, S.Katsuda, Y.Sakai, Journal of atherosclerosis and thrombosis24:530-538May. 2017
  • Effect of Collagen Tripeptide on Atherosclerosis in Healthy Humans, Naohisa Tomosugi, Shoko Yamamoto, Masayoshi Takeuchi, Hideto Yonekura, Yasuhito Ishigaki, Noriaki Numata, Shogo Katsuda, Yasuo Sakai, Journal of Atherosclerosis and Thrombosis24:530-538May. 2017
  • JunB regulates angiogenesis and neurovascular parallel alignment in mouse embryonic skin, Y.Yoshitomi,T.Ikeda,H.Saito,Y.Yoshitake,Y.Ishigaki,T.Hatta,N.Kato,H.Yonekura, Jonal of Cell Science130:916-926Jan. 2017
  • High FDG uptake on PET is associated with negative cell-to-cell adhesion molecule E-cadherin expression in lung adenocarcinoma., (Kotaro.Higashi), Yoshimichi.Ueda, Miyako.Shimasaki, Yasuhito.Ishigaki , Yuka.Nakamura, Managu.Oguchi, Tsutomu.Takegami, Naoto.Watanabe., Annals of nuclear medicine31:590-5952017
  • Proposed diagnostic criteria, disease severity classification, and tretment strategy for a novel disorder;TAFRO syndrome, Y.Masaki, H.Kawabata, K.Takai, N.Tsukamoto, S.Fujimoto, Y.Ishigaki, N.Kurose, M.Kojima, S.Nakamura, T.Kinoshita, S.Aoki, Japanese TAFRO syndrome research team57:195-203Oct. 2016
  • Effect of antifibrotic microRNAs crosstalk on the action of N-acetyl-seryl-aspartyl-lysyl-proline in diabetes-related kidney fibrosis., S.P.Srivastava, S.Shi, M.Kanasaki, T.Nagai, M.Kitada, J.He, Y.Nakamura, Y.Ishigaki, K.Kanasaki, D.Koya, Scientific reports6:29884-29884Jul. 2016
  • Learning impairment by minimal cortical injury in a mouse model of Alzheimer's disease., J.Zou, M.Wang, O.Uchiumi, Y.Shui, Y.Ishigaki, X.Liu, N.Tajima, T.Akai, H.Iizuka, N.Kato, Brain research1637:56-63Feb. 2016
  • Identification and functional analysis of an EMT-accelerating factor induced in pancreatic cancer cells by an anticancer agent, T.Shimasaki, S.Yamamoto, Y.Ishigaki, T.Takata, T.Arisawa, Y.Motoo, N.Tomosugi, T.Minamoto, Suizo31:76-842016
  • Correlation of HIF-1α/HIF-2α expression with FDG uptake in lung adenocarcinoma., (K.Higashi), T.Yamagishi, Y.Ueda, Y.Ishigaki, M.Shimasaki, Y.Nakamura, M.Oguchi, T.Takegami, M.Sagawa, H.Tonami, Annals of nuclear medicine30:708-7152016
  • Japanese encephalitis virus replication and inhibitory effect of shRNA in mice, M.Murakami, T.Tasaki, S.Nukuzuma, H.Minato, T.Nojima, Y.Ishigaki, T.Takegami, Advances in Microbiology6:462-4702016
  • Regulation of soluble Flt-1(VEGFR-1) production by hnRNP D and protein arginine methylation, T.Ikeda, Y.Yoshitomi, H.Saito, T.Shimasaki, H.Yamaya, T.Kobata, Y.Ishigaki, N.Tomosugi, Y.Yoshitake, H.Yonekura, Molecular and Cellular Biochemistry413:155-1642016
  • Formation of Pisoliths at Hot Springs in Saturnia, Toscana, Italy, (K.Tazaki), F.Tazaki, M.Okuno, T.Takehara, Y.Ishigaki, H.Nakagawa, The Journal of the Geological Society of Japan122:45-602016
  • Expression of amyloid-β in mouse cochlear hair cells causes an early-onset auditory defect in high-frequency sound perception., (Y.Omata), Tharasegaran Suganya, Lim Young-Mi, Y.Yamasaki, Y.Ishigaki, T.Tatsuno, M.Maruyama, L.Tsuda, Aging(Albany NY)8:1-142016
  • Ventromedial hypothalamic lesions Dowm-Reguiate the Expression of Adora1 Genes in rat Pancreatic islets, (T.Kiba), Y.Ishiagaki, LETTERS TO THE EDITOR45:e1-e22016
  • Nonsense-mediated mRNA decay factor Upf2 exists in both the nucleoplasm and the cytoplasm., T.Tatsuno, Y.Nakamura, Ma Shaofu, N.Tomosugi, Y.Ishigaki, Molecular medicine reports14:655-6602016
  • Proposed diagnostic criteria, disease severity classification and treatment strategy for TAFRO syndrome, 2015 version., Y.Masaki, H.Kawabata, K.Takai, M.Kojima, N.Tsukamoto, Y.Ishigaki , N.Kurose, M.Ide, J.Murakami, K.Nara, H.Yamamoto, Y.Ozawa, H.Takahashi, K.Miura, T.Miyauchi, S.Yoshida, A.Momoi, N.Awano, S.Ikushima, Y.Ohta, N.Furuta, S.Fujimoto, H.Kawanami, T.Sakai, T.Kawanami, Y.Fujita, T.Fukushima, S.Nakamura, T.Kinoshita, S.Aoki, International journal of hematology103:686-6922016
  • Proposed diagnostic criteria, disease severity classification, and treatment strategy for a novel disorder; TAFRO syndrome., Y.Masaki, H.Kawabata, K.Takai, N.Tsukamoto, S.Fujimoto, Y.Ishigaki, N.Kurose, M.Kojima, S.Nakamura, T.Kinoshita, S.Aoki, [Rinshō ketsueki] The Japanese journal of clinical hematology57:2029-20372016
  • Induction of memory deficit in mice with chronic exposure to cerebrospinal fluid from patients with Anti-N-Methyl-D-Aspartate receptor encephalitis, Y.Li, K.Tanaka, L.Wang, Y.Ishigaki, N.Kato, The Tohoku Journal of Experimental Medicine237:329-338Nov. 2015
  • Improvement of spatial learning by facilitating large-conductance calcium-activated potassium channel with transcranial magnetic stimulation in Alzheimer's disease model mice, F.Wang, Y.Zhang, L.Wang, P.Sun, X.Luo, Y.Ishigaki, T.Sugai, R.Yamamoto, N.Kato, Neuropharmacology97:210-219Jun. 2015
  • Induction murine models of chronic fatigue syndrome by brucella abortus antigen injections: is anemia induced or not?, J.Moriya, Q.He, H.Uenishi, S.Akazawa, J.Yamakawa, J.Kobayashi, Y.Ishigaki, Biomed Research International2015:191489May. 2015
  • Decreased expression of innate immunity-related genes in peripheral blood mononuclear cells from patients with IgG4-related disease, A.Nakajima, Y.Masaki, T.Nakamura, T.Kanawami, Y.Ishigaki, T.Takegami, M.Kawano, K.Yamada, N.Tsukamoto, S.Matsui, T.Saeki, K.Okazaki, T.Kamisawa, T.Miyashita, Y.Yakushijin, K.Fujikawa, M.Yamamoto, H.Hamano, T.Origuchi, S.Hirata, H.Tsuboi, T.Sumida, H.Morimoto, T.Sato, H.Iwao, M.Miki, T.Sakai, Y.Fujita, M.Tanaka, T.Fukushima, T.Okazaki, H.Umehara, PLoS One10:e0126582-e0126582May. 2015
  • Comparative genomics of the mucoid and nonmucoid strains of streptococcus pyogenes, isolated from the same patient with streptococcal meningitis, (H.Yoshida), Y.Ishigaki, A.Takizawa, K.Moro, Y.Kishi, T.Takahashi, H.Matsui3:e00221-15-e00221-15Apr. 2015
  • Experimental analysis of plastic materials containing radionuclides for decontamination viability, (K.Tazaki), M.Nakano, T.Takehara, Y.Ishigaki, H.Nakagawa69:99-108Mar. 2015
  • Expression of hyaluronidase-4 in a rat spinal cord hemisection model, Y.Tachi, T.Okuda, N.Kawahara, N.Kato, Y.Ishigaki, T.Matsumoto, Asian Spine Journal9:7-13Feb. 2015
  • Phosphorylation status of human RNA-binding protein 8A in cells and its inhibitory regulation by Magoh, Y.Ishigaki, Y.Nakamura, T.Tatsuno, S.Ma, N.Tomosugi, Experimental Biology and Medicine240:438-4452015
  • Hepatitis C virus NS3 protein modulates the biological behaviors of malignant hepatocytes by altering the expression of host cell microRNA, J.Zhang, Y.Ishigaki, T.Takegami, Molecular Medicine Reports12:5109-51152015
  • Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture., (A.Shimamoto), H.Kagawa, K.Zensho, Y.Sera, Y.Kazuki, M.Osaki, M.Oshimura, Y.Ishigaki, K.Hirashima, Y.Kodama, S.Yuasa, K.Fukuda, K.Hirashima, H.Seimiya, H.Koyama, T.Shimizu, M.Takemoto, K.Yokote, M.Goto, H.Tahara, PloS one9:e112900;1-13Nov. 2014
  • Reprogramming Suppresses Premature Senescence Phenotypes of Werner Syndrome Cells and Maintains Chromosomal Stability over Long-Term Culture, Shimamoto, Akira;Kagawa, Harunobu;Zensho, Kazumasa;Sera, Yukihiro;Kazuki, Yasuhiro;Osaki, Mitsuhiko;Oshimura, Mitsuo;Ishigaki, Yasuhito;Hamasaki, Kanya;Kodama, Yoshiaki;Yuasa, Shinsuke;Fukuda, Keiichi;Hirashima, Kyotaro;Seimiya, Hiroyuki;Koyama, Hirofumi;Shimizu, Takahiko;Takemoto, Minoru;Yokote, Koutaro;Goto, Makoto;Tahara, Hidetoshi, PLOS ONE9Nov. 2014
  • Case report of new building works adjacent to RI facility, M.Taniguchi, Y.Ishigaki13:177-180Nov. 2014
  • Global gene expression analysis with DNA microarray, Y.Ishigaki, T.Tatsuno, Y.Nakamura39:35-41Oct. 2014
  • Immunostaining and time-lapse analysis of vinblastine-induced paracrystal formation in human A549 cells., Y.Nakamura, Y.Ishigaki, Oncology letters8:2387-2392Sep. 2014
  • Linagliptin-mediated DPP-4 inhibition ameliorates kidney fibrosis in streptozotocin-induced diabetic mice by inhibiting endothelial-to-mesenchymal transition in a therapeutic regimen, K.Kanasaki, S.Shi, M.Kanasaki, J.He, T.Nagai, Y.Nakamura, Y.Ishigaki, M.Kitada, SP.Srivastava, D.Koya, Diabetes.63:2120-2131Jun. 2014
  • Linagliptin-Mediated DPP-4 Inhibition Ameliorates Kidney Fibrosis in Streptozotocin-Induced Diabetic Mice by Inhibiting Endothelial-to-Mesenchymal Transition in a Therapeutic Regimen, Kanasaki, Keizo;Shi, Sen;Kanasaki, Megumi;He, Jianhua;Nagai, Takako;Nakamura, Yuka;Ishigaki, Yasuhito;Kitada, Munehiro;Srivastava, Swayam Prakash;Koya, Daisuke, DIABETES63:2120-2131Jun. 2014
  • Observation of localization and structure of RNA-protein complexes using light and electron microscopy, Y.Ishigaki, Y.Nakamura, T.Tatsuno28:1-5May. 2014
  • N-acetyl-seryl-aspartyl-lysyl-proline inhibits diabetes-associated kidney fibrosis and endothelial-mesenchymal transition, T.Nagai, M.Kanasaki, SP.Srivastava, Y.Nakamura, Y.Ishigaki, M.Kitada, S.Shi, K.Kanasaki, D.Koya, BioMed research international [electronic resource]2014:696475;1-12Mar. 2014
  • Proteasome inhibitors and knockdown of SMG1 cause accumulation of Upf1 and Upf2 in human cells., X.Zhao, A.Nogawa, T.Matsunaga, T.Takegami, H.Nakagawa, Y.Ishigaki, International journal of oncology44:222-228Jan. 2014
  • Ventromedial hypothalamic lesions change the expression of cell proliferation-related genes and morphology-related genes in rat pancreatic islets, Kiba, Takayoshi;Ishigaki, Yasuhito, ISLETS62014
  • Role of RNA binding protein in cell cycle progression and centrosome maturation in human tumor cells, Ishigaki, Yasuhito;Nakamura, Yuka;Tatsuno, Takanori;Hashimoto, Mitsumasa;Shimasaki, Takeo;Iwabuchi, Kuniyoshi;Tomosugi, Naohisa, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE34:S68-S682014
  • RNA-binding protein RBM8A (Y14) and MAGOH localize to centrosome in human A549 cells, Ishigaki, Yasuhito;Nakamura, Yuka;Tatsuno, Takanori;Hashimoto, Mitsumasa;Iwabuchi, Kuniyoshi;Tomosugi, Naohisa, HISTOCHEMISTRY AND CELL BIOLOGY141:101-1092014
  • Case Report of New Building Works Adjacent to RI Facility, TANIGUCHI Makoto;ISHIGAKI Yasuhito, Japanese Journal of Radiation Safety Management13:177-1802014
  • Proteasome inhibitors and knockdown of SMG1 cause accumulation of Upf1 and Upf2 in human cells, Zhao, Xia;Nogawa, Atsushi;Matsunaga, Tsukasa;Takegami, Tsutomu;Nakagawa, Hideaki;Ishigaki, Yasuhito, INTERNATIONAL JOURNAL OF ONCOLOGY44:222-2282014
  • N-acetyl-seryl-aspartyl-lysyl-proline Inhibits Diabetes-Associated Kidney Fibrosis and Endothelial-Mesenchymal Transition, Nagai, Takako;Kanasaki, Megumi;Srivastava, Swayam Prakash;Nakamura, Yuka;Ishigaki, Yasuhito;Kitada, Munehiro;Shi, Sen;Kanasaki, Keizo;Koya, Daisuke, BIOMED RESEARCH INTERNATIONAL2014
  • Immunostaining and time-lapse analysis of vinblastine-induced paracrystal formation in human A549 cells, Nakamura, Yuka;Ishigaki, Yasuhito, ONCOLOGY LETTERS8:2387-23922014
  • Inhibition of mTORC2 but not mTORC1 up-regulates E-cadherin expression and inhibits cell motility by blocking HIF-2α expression in human renal cell carcinoma., (S.Maru), Y.Ishigaki, N.Shinohara, T.Takata, N.Tomosugi, K.Nonomura, The Journal of urology.189:1921-1929.May. 2013
  • SEM-EDX Elemental content maps of organisms in radioac-tive environmental pollution by FDNPP accident in 2011., (K.Tazaki), T.Takehara, Y.Ishigaki, H.Nakagawa, N.Nemoto, A.Yokoyama, H.Kimura16:7-24Mar. 2013
  • Aberrant glycogen synthase kinase 3β is involved in pancreatic cancer cell invasion and resistance to therapy., (A.Kitano), T.Shimasaki, Y.Chikano, M.Nakada, M.Hirose, T.Higashi, Y.Ishigaki, Y.Endo, T.Takino, H.Sato, Y.Sai, K.Miyamoto, Y.Motoo, K.Kawakami, T.Minamoto, PloS one8:e55289;1-12Feb. 2013
  • Meaning of tumor protein 53-induced nuclear protein 1 in the molecular mechanism of gemcitabine sensitivity., N.Nakaya, Y.Ishigaki, H.Nakajima, M.Murakami, T.Shimasaki, T.Takata, M.Ozaki, NJ.Dusetti, JL.Iovanna, Y.Motoo, Molecular and clinical oncology.1:100-104Jan. 2013
  • Distribution of Sr,Cs,Np,and Pu in radioactive polluted paddy soils and organisms., (K.Tazaki), T.Takehara, Y.Ishigaki, H.Nakagawa46:35-572013
  • RNA-binding protein RBM8A (Y14) and MAGOH localize to centrosome in human A549 cells., Y.Ishigaki, Y.Nakamura, T.Tatsuno, M.Hashimoto, K.Iwabuchi, N.Tomosugi, Histochemistry and cell biology.141:101-1092013
  • Effect of porcine placental extract on collagen production in human skin fibroblasts In Vitro, (C.Yoshikawa), F.Takano, Y.Ishigaki, M.Okada, S.Kyo, N,Suzuki, K.Sugiura, K.Koike, Gynecology & obstetrics : current research. [electronic resource]3:1000186;1-42013
  • Depletion of RNA-binding protein RBM8A (Y14) causes cell cycle deficiency and apoptosis in human cells., Y.Ishigaki, Y.Nakamura, T.Tatsuno, M.Hashimoto, T.Shimasaki, K.Iwabuchi, N.Tomosugi, Experimental biology and medicine (Maywood, N.J.)238:889-8972013
  • Chk1-mediated phosphorylation of receptor-associated late transducer at serine 250 increases its stability by stimulating its interaction with 14-3-3., K.Takeda, T.Takata, Y.Kawai, Y.Ishigaki, K.Kajinami, Genes to cells : devoted to molecular & cellular mechanisms18:369-3862013
  • Characterization of proteins secreted by pancreatic cancer cells with anticancer drug treatment in vitro, T.Takata, Y.Ishigaki, T.Shimasaki, H.Tsuchida, Y.Motoo, A.Hayashi, N.Tomosugi, Oncology reports.28:1968-1976Dec. 2012
  • Use of ionic liquid in fungal taxonomic study of ultrastructure of basidiospore ornamentation, (K.Yanaga), N.Maekawa, N.Shimomura, Y.Ishigaki, Y.Nakamura, T.Takegami, N.Tomosugi, S.Miyazawa, S.Kuwabata, Mycological Progress11:343-347Nov. 2012
  • Expression pattern of Galectin 4 in rat placentation, Tomohiro Arikawa, Eriko Simamura, Hiroki Shimada, Nozomu Nishi, Takanori Tatsuno, Yasuhito Ishigaki, Naohisa Tomosugi, Chizu Yamashiro, Toshiyuki Hata, Tsutomu Takegami, Tomonori Nakamura, Haruta Mogami, Ken Yamaguchi, Hiroki Otani, Toshihisa Hatta, Hiroki Shoji, Placenta2012 Aug 6. [Epub ahead of print]Aug. 2012
  • Expression pattern of Galectin 4 in rat placentation, T.Arikawa, E.Shimamura, H.Shimada, N.Nishi, T.Tatsuno, Y.Ishigaki, N.Tomosugi, C.Yamashiro, T.Hata, T.Takegami, H.Mogami, K.Yamaguchi, T.Nakamura, H.Otani, T.Hatta, H.Shoji, Placenta33:885-887Aug. 2012
  • Loss of HITS(FAM107B) expression in cancers of multiple organs: tissue microarray analysis, (H.Nakajima), K.Koizumi, T.Tanaka, Y.Ishigaki, Y.Yoshitake, H.Yonekura, T.Sakuma, T.Fukushima, H.Umehara, S.Ueno, T.Minamoto, Y.Motoo, International journal of oncology41:1347-1357May. 2012
  • Observation of live ticks (Haemaphysalis flava) by scanning electron microscopy under high vacuum pressure, Y.Ishigaki, Y.Nakamura, Y.Oikawa, Y.Yano, S.Kuwabata, H.Nakagawa, N.Tomosugi, T.Takegami, PloS one7:e32676 1-6Mar. 2012
  • Glycogen synthase kinase 3βinhibition sensitizes pancreatic cancer cells to gemcitabine, T.Shimasaki, Y.Ishigaki, Y.Nakamura, T.Takata, N.Nakaya, H.Nakajima, I.Sato, X.Zhao, A.Kitano, K.Kawakami, T.Tanaka, T.Takegami, N.Tomosugi, T.Minamoto, Y.Motoo, Journal of gastroenterology.47:321-333Mar. 2012
  • Garlic extract and its selected organosulphur constituents promote ileal immune responses ex vivo., (N Ota), F Takano, S Muroga, T Kawabata, Y.Ishigaki, N Yahagi, T Ohta, Journal of functional foods4:243-252Jan. 2012
  • A novel clinical entity, IgG4-related disease (IgG4RD): general concept and details, H.Umehara, K.Okazaki, Y.Masaki, M.Kawano, M.Yamamoto, T.Saeki, S.Matsui, T.Sumida, T.Mimori, Y.Tanaka, K.Tsubota, T.Yoshino, S.Kawa, R.Suzuki, T.Takegami, N.Tomosugi, N.Kurose, Y.Ishigaki, A.Azumi, M.Kojima, S.Nakamura, D.Inoue, Modern rheumatology / the Japan Rheumatism Association.22:1-142012
  • Comparative study of hydrophilic and hydrophobic ionic liquids for observing cultured human cells by scanning electron microscopy., Y.Ishigaki, Y.Nakamura, T.Takehara, T.Kurihara, H.Koga, T.Takegami, H.Nakagawa, N.Nemoto, N.Tomosugi, S.Kuwabata, S.Miyazawa, Microscopy research and technique74:1104-1108Dec. 2011
  • Role of amino acid transporter LAT2 in the activation of mTORC1 pathway and the pathogenesis of crescentic glomerulonephritis, (R.Kurayama), N.Ito, Y.Nishibori, D.Fukuhara, Y.Akimoto, E.Higashihara, Y.Ishigaki, Y.Sai, K.Miyamoto, H.Endou, Y.Kanai, K.Yan, Laboratory investigation; a journal of technical methods and pathology.91:992-1006Jul. 2011
  • Hypoxia down-regulates sFlt-1 (sVEGFR-1) expression in human microvascular endothelial cells by a mechanism involving mRNA alternative processing, T.Ikeda, L.Sun, N.Tsuruoka, Y.Ishigaki, Y.Yoshitomi, Y.Yoshitake, H.Yonekura, The Biochemical journal.436:399-407Jun. 2011
  • VEGF-A and its isoform VEGF121 mRNA expression measured by quantitative real-time RT-PCR: correlation with F-18 FDG uptake and aggressiveness of lung adenocarcinoma: preliminary study, (J.F.Guo), K.Higashi, Y.Ueda, Y.Ishigaki, T.Sakuma, M.Oguchi, T.Takegami, Y.Ohta, L.Zhang, K.Xu, H.Nishida, H.Tonami, Annals of nuclear medicine.25:29-36May. 2011
  • Resveratrol improves hippocampal atrophy in chronic fatigue mice by enhancing neurogenesis and inhibiting apoptosis of granular cells, J.Moriya, R.Chen, J.Yamakawa, K.Sasaki, Y.Ishigaki, T.Takahashi, Biological & pharmaceutical bulletin34:354-359Mar. 2011
  • Inhibitory effects of statins on cytomegalovirus production in human cells: comprehensive analysis of gene expression profiles, (T.Murayama), C.Bi, Y.Li, Y.Ishigaki, F.Takano, T.Takegami, T.Ohta, H.Sumino, K.Ubukata, T.Takahashi, Journal of experimental and clinical medicine3:40-45Feb. 2011
  • Comprehensive analysis of alternative splicing and functionality in neuronal differentiation of P19 cells., (H.Suzuki), K.Ozaki, K.Sano, A.H.M.Khurshid Alam, Y.Nakamura, Y.Ishigaki, K.Kawahara, T.Tsukahara, PloS one6:e16880,1-11Feb. 2011
  • Ultraviolet B-induced expression of amphiregulin and growth differentiation factor 15 in human lens epithelial cells, H.Osada, Y.Yoshitake, T.Ikeda, Y.Ishigaki, T.Takata, N.Tomosugi, H.Sasaki, H.Yonekura, Molecular vision17:159-169Jan. 2011
  • Metabolic disorder, inflammation, and deregulated molecular pathways converging in pancreatic cancer development: Implications for new therapeutic strategies, Y.Motoo, T.Shimasaki, Y.Ishigaki, H.Nakajima, K.Kawakami, T.Minamoto, Cancers3:446-460Jan. 2011
  • Scanning electron microscopy with an ionic liquid reveals the loss of mitotic protrusions of cells during the epithelial-mesenchymal transition, Y.Ishigaki, Y.Nakamura, T.Takehara, T.Shimasaki, T.Tatsuno, F.Takano, Y.Ueda, Y.Motoo, T.Takegami, H.Nakagawa, S.Kuwabata, N.Nemoto, N.Tomosugi, S.Miyazawa, Microscopy research and technique74:1024-10312011
  • Human SMG-1 is involved in gemcitabine-induced primary microRNA-155/BIC up-regulation in human pancreatic cancer PANC-1 cells, (QS.Xia), Y.Ishigaki, X.Zhao, T.Shimasaki, H.Nakajima, H.Nakagawa, T.Takegami, ZH.Chen, Y.Motoo, Pancreas.40:55-60Jan. 2011
  • Ultrastructural localization of Upf2 and its binding to mRNA molecules in human cells, Y.Ishigaki, T.Kurihara, Y.Nakamura, X.Zhao, T.Takata, S.Izumi, T.Takegami, N.Tomosugi, H.Nakagawa24:8-13Nov. 2010
  • Ionic liquid enables simple and rapid sample preparation of human culturing cells for scanning electron microscope analysis, Y.Ishigaki, Y.Nakamura, T.Takehara, N.Nemoto, T.Kurihara, H.Koga, H.Nakagawa, T.Takegami, N.Tomosugi, S.Miyazawa, S.Kuwabata, Microscopy research and technique74:415-420Sep. 2010
  • Aquaporin as a novel player in cancer cell the invasion of cancer cells, Y.Ueda, M.Shimasaki, Y.Machida, Y.Takahara, Y.Himi, Y.Ishigaki, K.Sato, T.Sakuma, H.Toga, S.Kawakami, S.Katsuda35:55-60Aug. 2010
  • Carotenoids modulate cytokine production in Peyer's patch cells ex vivo., (M.Yamaguchi), I.Hasegawa, N.Yahagi, Y.Ishigaki, F.Takano, T.Ohta, Journal of agricultural and food chemistry58:8566-8572Aug. 2010
  • Gene expression profiling in rat pancreas after ventromedial hypothalamic lesioning., (T.Kiba), Y.Kintaka, Y.Suzuki, N.Ishizuka, Y.Ishigaki, S.Inoue, Pancreas.39:627-632Jul. 2010
  • VMH lesions downregulate the expression of Per2 gene in the pancreas in the rat., (T.Kiba), Y.Kintaka, Y.Suzuki, N.Ishizuka, Y.Ishigaki, S.Inoue, Neuroscience letters.471:148-151May. 2010
  • Assessment of VEGF-D expression measured by immunohistochemical staining and F-18 FDG uptake on PET as biological prognostic factors for recurrence in patients with surgically resected lung adenocarcinoma, L.Zhang, K.Higashi, Y.Ishigaki, Y.Ueda, T.Sakuma, T.Takegami, M.Oguchi, K.Xu, Y.Ohta, H.Nishida, H.Tonami, Annals of nuclear medicine.24:533-540May. 2010
  • Application of molecular medicine to pancreatic cancer, T.Shimasaki, Y.Ishigaki, T.Minamoto, Y.Motoo25:35-45Jan. 2010
  • Molecular analysis on responses of TP53INP1-knockout mouse embryonic fibroblasts to anti-cancer agents, (Q.Bian), Y.Motoo, H.Nakajima, T.Shimasaki, Y.Ishigaki125-1282010
  • Induction of HITS, a newly identified family with sequence similarity 107 protein (FAM107B), in cancer cells by heat shock stimulation, H.Nakajima, Y.Ishigaki, QI-S.Xia, T.Ikeda, Y.Yoshitake, H.Yonekura, T.Nojima, T.Tanaka, H.Umehara, N.Tomosugi, T.Takata, T.Shimasaki, N.Nakaya, I.Sato, K.Kawakami, K.Koizumi, T.Minamoto, Y.Motoo, International journal of oncology37:583-5932010
  • Introduction of OLS inNIBB, Y.Ishigaki, T.Takata, N.Tomosugi, T.Takegami, H.Nakagawa8:15-18Dec. 2009
  • An emerging strategy for cancer treatment targeting aberrant glycogen synthase kinase 3beta., (K.Miyashita), M.Nakada, K.Shakoori, Y.Ishigaki, T.Shimasaki, Y.Motoo, Kawakami K, T.Minamoto, Anti-cancer agents in medicinal chemistry9:1114-1122Dec. 2009
  • Gene Expression Profiling in Rat Liver After VMH Lesioning., (T.Kiba), Y.Kintaka, Y.Suzuki, E.Nakata, Y.Ishigaki, S.Inoue, Experimental biology and medicine (Maywood, N.J.)234:758-763Jul. 2009
  • Ventromedial hypothalamic lesions change the expression of neuron-related genes and immune-related genes in rat liver., (T.Kiba), Y.Kintaka, Y.Suzuki, E.Nakata, Y.Ishigaki, S.Inoue, Neuroscience letters.455:14-16May. 2009
  • Isolation of N-acetylneuraminic acid and N-glycolylneuraminic acid from Pleurocybella porrigens., T.Takata, T.Hasegawa, T.Tatsuno, J.Date, Y.Ishigaki, Y.Nakamura, N.Tomosugi, F.Takano, T.Ohta, Journal of health science (Tokyo, Japan)55:373-379Mar. 2009
  • Changes of neuron-specific and apoptosis gene expression levels after ventromedial hypothalamic lesions in rat intestine, (T.Kiba), Y.Kintaka, Y.Suzuki, E.Nakata, T.Osaka, Y.Ishigaki, S.Inoue, Experimental biology and medicine (Maywood, N.J.)233:1368-1373Dec. 2008
  • The kampo medicines orengedokuto, bofutsushosan and boiogito have different activities to regulate gene expressions in differentiated rat white adipocytes: comprehensive analysis of genetic profiles, J.Yamakawa, Y.Ishigaki, F.Takano, T.Takahashi, J.Yoshida, J.Moriya, T.Takata, T.Tatsuno, K.Sasaki, T.Ohta, T.Takegami, F.Yoshizaki, Biological & pharmaceutical bulletin31:2083-2089Nov. 2008
  • The Kampo Medicines Orengedokuto, Bofutsuhosan and Boiogito Have Different Activities to Regulate Gene expressions in differentiated Rat White Adipocytes : Comprehensive Analysis of Genetic Profiles, J.Yamakawa, Y.Ishigaki, F. Takano, T. Takahashi, J. Yoshida, J.Moriya, T.Takata, T. Tatsuno, K. Sasaki, T. Ohta, T.Takegami, F. Yoshizaki, Biological & pharmaceutical bulletin31: 2083-2089Nov. 2008
  • The liquid culture filtrates of entomogenous fungus Paecilomyces tenuipes and its glycoprotein constituent protects against anemia in mice treated with 5-fluorouracil, (T.Takata), T.Taanaka, N.Yahagi, R.Yahagi, H.Tsuchida, Y.Ishigaki, N.Tomosugi, S.Fushiya, F.Takano, T. Ohta, Biological & pharmaceutical bulletin31:1565-1573Aug. 2008
  • The Liquid Culture of Entomogenous fungus Paecilomyces tenuipes and Its Glycoprotein Costituent Protects against Anemia in Mice Treated with 5-fluorouracil., T. Takata, T. Tanaka, N. Yahagi, R. Yahagi, H. Tsuchida, Y.Ishigaki, N.Tomosugi, S. Fushiya, F. Takano, T. Ohta, Biological & pharmaceutical bulletin31 : 1561-1573Aug. 2008
  • Bioreductive activation of quinone antitumor drugs by mitochondrial voltage-dependent anion channel 1, E.Simamura, H.Shimada, Y.Ishigaki, T.Hatta, N.Higashi, K-I.Hirai, Anatomical science international / Japanese Association of Anatomists83:261-266Aug. 2008
  • Copmparative study of chromosomal analysis using SNPs genotyping arrays and G-banding in MCA/MR(multiple congenital abnormality / mental retardation) patients, M.Ozaki, Y.Ishigaki33:1-12Jun. 2008
  • Multiple shRNA expressions in a single plasmid vector improve RNAi against the XPA gene, (A.Nagao), X.Zhao, T.Takegami, H.Nakagawa, S.Matsui, T.Matsunaga, Y.Ishigaki, Biochemical and biophysical research communications370:301-3052008
  • High-quality RNA extraction from rat pancreas for microarray analysis, (Kiba T), Y.Kintaka, E.Nakada, Y.Suzuki, S.Inoue, Y.Ishigaki, Pancreas.35:98-100Jul. 2007
  • Apoptosis-related gene expression profile is changed by gemcitabine in pancreatic cancer cell line(PANC-1), T.Shimasaki, Y.Ishigaki, T.Minato, Y.Motoo22:14-20Mar. 2007
  • UV-B protective effect of a polyacylated anthocyanin, HBA, in flower petals of the blue morning glory, Ipomoea tricolor cv. Heavenly Blue., Bioorg Med Chem13:2015-20202005
  • Human NTH1 physically interacts with p53 and proliferating cell nuclear antigen., ISHIGAKI Yasuhito, Biochem. Biophys. Res. Commun.2004
  • cDNA cloning of the chiken DDB1 gene encoding the p127 subunit of damaged DNA-binding protein, ISHIGAKI Yasuhito, GENES & GENETIC SYSTEMS2003
  • Photodegradation of 4-alkylphenols using BiO4 photocatalyst under irradiation with visible light from a solar simulator., ISHIGAKI Yasuhito, Applied Catalysis B: Environmental2003
  • A case withcongenital photosensitivity,hairloss, growth failure and pulmonary stenosis relation with Rothmund-Thomson synderome., ISHIGAKI Yasuhito, Clin. Pediatr. Endocrinology2003
  • The exon-exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: Dynamics of mRNP remodeling, (F.Lejeune), Y.Ishigaki, X.Li, L.E.Maquat, The EMBO journal.13:3536-35452002
  • Photocatalytic degradation of 4-n-Nonylphenol under irradiation from solar simulator: Comparison between BiVO4 and TiO2 photocatalysts., ISHIGAKI Yasuhito, Chem. Lett.2002
  • An ultraviolet-B-resistant mutant with enhanced DNA repair in Arabidopsis., ISHIGAKI Yasuhito, Plant physiology2002
  • Evidence that phosphorylation of human Upfl protein, ISHIGAKI Yasuhito, RNA2001
  • Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20, Y.Ishigaki, X.Li, G.Serin, L.E.Maquat, Cell106(5):607-6172001
  • Development and characterization of a DNA solar dosimeter., ISHIGAKI Yasuhito, JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY1999
  • Supranuclear melanin caps reduce ultraviolet induced DNA photoproducts in human epidermis., ISHIGAKI Yasuhito, JOURNAL OF INVESTIGATIVE DERMATOLOGY1998
  • Enhanced human tumor cell transplantability in a new congenic immunodeficient mouse; KSN-BNX., ISHIGAKI Yasuhito, FOLIA MICROBIOLOGICA1998
  • An UVB-carcinogenesis model with KSN nude mice., ISHIGAKI Yasuhito, JOURNAL OF RADIATION RESEARCH1998
  • A comparison of UVB-carcinogenesis between nude mice and nude beige mice, ISHIGAKI Yasuhito, Journal of Radiation Research1998
  • New immunodeficient mouse strains bred by introducing beige and xid mutations into the KSN nude strain, ISHIGAKI Yasuhito, LABORATORY ANIMAL SCIENCE1996
  • Photorepair and excision repair removal of UV-induced pyrimidine dimers and (6-4) photoproducts in the tail fin of the medaka, Oryzias latipes, ISHIGAKI Yasuhito, JOURNAL OF RADIATION RESEARCH1994
  • Ultraviolet B-induced Otx2 expression in lens epithelial cells promotes epithelial-mesenchymal transition, Yoshitomi Y, Osada H, Satake H, Kojima M, Saito-Takatsuji H, Ikeda T, Yoshitake Y, Ishigaki Y, Kubo E, Sasaki H, Yonekura H, Biology Open8:bio035691Feb. 2019
  • High‐salt diet promotes crystal deposition through hypertension in Dahl salt‐sensitive rat model, Yusuke Nakazawa, Shinya Inoue, Yuka Nakamura, Yasuo Iida, Yasuhito Ishigaki, Katsuhito Miyazawa, International journal of urology26:839-846Jun. 2019
  • The stability of Magoh and Y14 depends on their heterodimer formation and nuclear localization, Qingfeng Ma, Takanori Tatsuno, Yuka Nakamura, Yasuhito Ishigaki, Biochemical and Biophysical Research Communications511:631-636Apr. 2019
  • Immuno-detection of mRNA-binding protein complex in human cells under transmission electron microscopy, Qingfeng Ma, Takanori Tatsuno, Yuka Nakamura, Shin-Ichi Izumi, Naohisa Tomosugi, Yasuhito Ishigaki, MICROSCOPY RESEARCH AND TECHNIQUE82:680-688Jun. 2019
  • GLCCI1 is a novel protector against glucocorticoid-induced apoptosis in T cells, (Zentaro Kiuchi), YukinoNishibori, Satoru Kutsuna, Masashi Kotani, Ichiro Hada, Toru Kimura, Toshiyuki Fukutomi, Daisuke Fukuhara, Noriko Ito-Nitta, Akihiko Kudo, Takanobu Takata, Yasuhito Ishigaki, Naohisa Tomosugi, Hirotoshi Tanaka, Satsuki Matsushima, Shinya Ogasawara, Yoshiaki Hirayama, Hiromu Takematsu, Kunimasa Yan, FASEB JOURNAL33:7387-7402Jun. 2019
  • Neuroinflammation, Oxidative Stress, and Neurogenesis in a Mouse Model of Chronic Fatigue Syndrome, and the Treatment With Kampo Medicine, Qiang He, Mio Sawada, Naruhiro Yamasaki, Sumiyo Akazawa, Hisakazu Furuta, Hiroaki Uenishi, Xiangjin Meng, Takeshi Nakahashi, Yasuhito Ishigaki, Junji Moriya, Biological & pharmaceutical bulletin43:110-1152020
  • 2019 updated diagonostic criteria and disease severity classification for TAFRO syndrome, Yasufumi Masaki, Hiroshi Kawabata, Kazue Takai, Norifumi Tsukamoto, Shino Fujimoto, Yasuhito Ishigaki, Nozomu Kurose, Katsuhiro Miura, Shigeo Nakamura, Sadao Aoki; Japanese TAFRO Syndrome Research Team., International Jurnal of Hematology111:155-1582020
  • Impaired expression of innate immunity-related genes in IgG4-related disease: A possible mechanism in the pathogenesis of IgG4-RD, Takuji Nakamura, Tomomi Satoh-Nakamura, Akio Nakajima, Takafumi Kawanami, Tomoyuki Sakai, Yoshimasa Fujita, Haruka Iwao, Miyuki Miki, Yasufumi Masaki, Toshiro Okazaki, Yasuhito Ishigaki, Mitsuhiro Kawano, Kazunori Yamada, Shoko Matsui, Takako Saeki, Terumi Kamisawa, Motohisa Yamamoto, Hideaki Hamano, Tomoki Origuchi, Shintaro Hirata, Yoshiya Tanaka, Hiroto Tsuboi, Takayuki Sumida, Kazuichi Okazaki, Masao Tanaka, Tsutomu Chiba, Tsuneo Mimori and Hisanori Umehara30:5512020

Books etc

  • Japanese Encephalitis Virus Infection and Replication: Biological Roles of Nonstructural Protein NS4a and The 3'-Untranslated Region in Persistent Infection
    Japanese Encephalitis
    T.Takegami, T.Tasaki, M.Murakami, Y.Ishigaki, M.Taniguchi, T.Nojima, S.Nukuzuma
    SMGroup (USA)  Aug. 2015
    www.smgebooks.com


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