SAITO Takashi

Researcher Profile & Settings

Research

Overview of research:
Treatment for metabolic syndrome

Degree

• Ph.D in Medicine

Research Activities

Published Papers

• Inhibition of γ-glutamyltransferase ameliorates ischemia-reoxygenation tissue damage in rats with hepatic steatosis, Ryuichi Kubota, Nobuhiko Hayashi, Kaori Kinoshita, Takashi Saito, Kazuaki Ozaki, Yoshimichi Ueda, Mutsumi Tsuchishima, Mikihiro Tsutsumi, Joseph George, British Journal of Pharmacology, 177:5195-5207, Nov. 2020
  DOI:10.1111/bph.15258
• Recombinant thrombomodulin prevented hepatic ischemia-reperfusion injury by inhibiting high-mobility group box 1 in rats, Yuki Hirakawa, Mutsumi Tsuchishima, Atsushi Fukumura, Kaori Kinoshita, Nobuhiko Hayashi, Takashi Saito, Joseph George, Toshikuni Nobuyuki, Ueda Yoshimichi, Tsutsumi Mikihiro, European Journal of Pharmacology, 863:172681, Dec. 2019
• The combination of fatty liver and increased gamma-glutamyl transpeptidase levels as a risk factor for atherosclerotic plaque development in apparently healthy people, Kaori Kinoshita, Nobuyuki Toshikuni, Takashi Saito, Nobuhiko Hayashi, Takahiro Minato, Yasuhiro Matsue, Yoshimichi Ueda, Mutsumi Tsuchishima, Mikihiro Tsutsumi, Turkish Journal of Medical Scences, 49:1350-1357, Oct. 2019
• Serum osteopontin predicts degree of hepatic fibrosis and serves as a biomarker in patients with hepatitis C virus Infection, Y.Matsue, M.Tsutsumi, N.Hayashi, T.Saito, M.Tsuchishima, N.Toshikuni, T.Arisawa, J.George, PLoS One, 10:e0118744-e0118744, 2015
  DOI:10.1371/journal.pone.0118744
• Pathogenesis of alcoholic chronic hepatitis, N.Hayashi, T.Saito, M.Kakuda, Y.Matsue, T.Minato, A.Fukumura, K.Ozaki, M.Tsuchisima, M.Tsutsumi, 49:219-226, Oct. 2014
• Binge alcohol consumption aggravates oxidative stress and promotes pathogenesis of NASH from obesity-lnduced simple steatosis, T.Minato, M.Tsutsumi, M.Tsuchishima, N.Hayashi, T.Saito, Y.Matsue, N.Toshikuni, T.Arisawa, J.George, Molecular medicine (Cambridge, Mass.), 20:490-502, 2014
• Irsogladine maleate for the treatment of recurrent aphthous stomatitis in hepatitis C virus patients on pegylated-interferon and ribavirin: a pilot study., N.Hayashi, J.George, H.Shiroeda, T.Saito, N.Toshikuni, M.Tsuchishima, T.Arisawa, M.Tsutsumi, Journal of gastroenterology and hepatology., 28:1015-1018, Jun. 2013
• Influence of IL17A polymorphisms (rs2275913 and rs3748067) on the susceptibility to ulcerative colitis, R.Hayashi, T.Tahara, H.Shiroeda, T.Saito, M.Nakamura, M.Tsutsumi, T.Shibata, T.Arisawa, Clinical and experimental medicine, 13:239-244, 2013
• Genetic polymorphisms of SCN10A are associated with functional dyspepsia in Japanese subjects., T.Arisawa, T.Tahara, H. Shiroeda, T.Minato, Y.Matsue, T.Saito, T.Fukuyama, T.Otsuka, A.Fukumura, M.Nakamura, T.Shibata, Journal of gastroenterology., 48:73-80, 2013
• -449 C>G polymorphism of NFKB1 gene, coding nuclear factor-kappa-B, is associated with the susceptibility to ulcerative colitis, R.Hayashi, T.Tahara, T.Yamaaki, T.Saito, K.Matsunaga, N.Hayashi, A.Fukumura, K.Ozaki, M.Nakamura, H.Shiroeda, M.Tsutsumi, T.Shibata, T.Arisawa, World journal of gastroenterology : WJG., 18:6981-6986, Dec. 2012
• Association between functional promoter polymorphisms of macrophage migration inhibitory factor(MIF)gene and ulcerative colitis in Japan, H.Shiroeda, T.Tahara, M.Nakamura, T.Shibata, T.Nomura, H.Yamada, R.Hayashi, T.Saito, M.Yamada, T.Fukuyama, T.Otsuka, H.Yano, K.Ozaki, M.Tsuchishima, M.Tsutsumi, T.Arisawa, Cytokine., 51:173-177, May 2010
• A case ob jejunal GIST diagnosed by double-baloon endoscopy, S.Siroeda, H.Siroeda, T.Ootsuka, M.Yamada, T.Fukuyama, T.Saito, R.Hayashi, T.Nomura, H.Yano, K.Ozaki, T.Arisawa, M.Yokoi, T.Kosaka, M.Tsutsumi, ENDOSCOPIC FORUM for digestive disease, 26:44-49, 2010
• Functional promoter polymorphisms of macrophage migration inhibitory factor in peptic ulcer diseases, H.Shiroeda, T.Tahara, M.Nakamura, T.Shibata, H.Yamada, T.Nomura, R.Hayashi, T.saito, T.Fukuyama, T.Otsuka, H.Yano, K.Ozaki, M.Tsuchishima, M.Tsutsumi, T.Arisawa, International journal of molecular medicine, 26:707-711, 2010
• Surgical implanation of human adipose derived stem cells attenuates experimentally induced hepatic fibrosis in rats, 28: 143:s10020-022-00566-6, Nov. 2022