Kanazawa Taro

FacultyKanazawa Medical University
PositionProfessor

Researcher Profile & Settings

Profile & Settings

    Birthday:  19571226

Contact

Education

  • Nagoya University Graduate School Division of Medicine
  • Nagoya University Faculty of Science

Academic & Professional Experience

  • Apr. 2006Kanazawa Medical University Professor
  • Apr. 1996Mar. 2006Kanazawa University Associate professor
  • Dec. 1994Mar. 1996Tohoku University Associate professor
  • Nov. 1990Nov. 1994Tohoku University Assistant professor
  • Apr. 1985Nov. 1990Kissei Pharmaceutical Co., Ltd. Researcher

Research Activities

Published Papers

  • Effect of Collagen Tripeptide on Atherosclerosis in Healthy Humans, Naohisa Tomosugi; Shoko Yamamoto; Masayoshi Takeuchi; Hideto Yonekura; Yasuhito Ishigaki; Noriaki Numata; Shogo Katsuda; Yasuo Sakai, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS24:530-5382017
  • Effect of Collagen Tripeptide on Atherosclerosis in Healthy Humans, Naohisa Tomosugi; Shoko Yamamoto; Masayoshi Takeuchi; Hideto Yonekura; Yasuhito Ishigaki; Noriaki Numata; Shogo Katsuda; Yasuo Sakai, JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS24:530-5382017
  • JunB regulates angiogenesis and neurovascular parallel alignment in mouse embryonic skin, Y.Yoshitomi; T.Ikeda; H.Saito; Y.Yoshitake; Y.Ishigaki; T.Hatta; N.Kato; H.Yonekura, Jonal of Cell Science130:916-926Jan. 2017
  • Regulation of soluble Flt-1 (VEGFR-1) production by hnRNP D and protein arginine methylation, Takayuki Ikeda; Yasuo Yoshitomi; Hidehito Saito; Takeo Shimasaki; Hideki Yamaya; Takashi Kobata; Yasuhito Ishigaki; Naohisa Tomosugi; Yoshino Yoshitake; Hideto Yonekura, MOLECULAR AND CELLULAR BIOCHEMISTRY413:155-164Feb. 2016
  • Regulation of soluble Flt-1(VEGFR-1) production by hnRNP D and protein arginine methylation, T.Ikeda; Y.Yoshitomi; H.Saito; T.Shimasaki; H.Yamaya; T.Kobata; Y.Ishigaki; N.Tomosugi; Y.Yoshitake; H.Yonekura, Molecular and Cellular Biochemistry413:155-1642016
  • Osteocytic cell necrosis is caused by a combination of glucocorticoid-induced Dickkopf-1 and hypoxia, S.Ueda; T.Ichiseki; Y.Yoshitomi; H.Yonekura; Y.Ueda; A.Kaneuji; T.Matsumoto, Medical Molecular Morphology48:69-75Jun. 2015
  • Melanocortins contribute to sequential differentiation and enucleation of human erythroblasts via melanocortin receptors 1, 2 and 5, E.Simamura; T.Arikawa; T.Ikeda; H.Shimada; H.Shoji, H,Masuta; Y.Nakajima; H.Otani; H.Yonekura; T.Hatta, PLoS One10:e0123232-e01232322015
  • Low-molecular weight fractions of Japanese soy sauce act as a RAGE antagonist via inhibition of RAGE trafficking to lipid rafts., S.Munesue; Y.Yamamoto; R.Urushihara; K.Inomata; H.Saito; S.Motoyoshi; T.Watanabe; H.Yonekura; H.Yamamoto, Food & function.4:1835-1842Dec. 2013
  • Low molecular weight heparin suppresses receptor for advanced glycation end products-mediated expression of malignant phenotype in human fibrosarcoma cells., A.Takeuchi; Y.Yamamoto; S.Munesue; A.Harashima; T.Watanabe; H.Yonekura; H.Yamamoto; H.Tsuchiya, Cancer science.104:740-749Jun. 2013
  • Identification of a major enzyme for the synthesis and hydrolysis of cyclic ADP-ribose in amphibian cells and evolutional conservation of the enzyme from human to invertebrate, T.Ikeda; S.Takasawa; N.Noguchi; K.Nata; A.Yamauchi; I.Takahashi; T.Yoshikawa; A.Sugawara; H.Yonekura; H.Okamoto, Molecular and cellular biochemistry.366:69-80Jul. 2012
  • Loss of HITS(FAM107B) expression in cancers of multiple organs: tissue microarray analysis, H.Nakajima; K.Koizumi; T.Tanaka; Y.Ishigaki; Y.Yoshitake; H.Yonekura; T.Sakuma; T.Fukushima; H.Umehara; S.Ueno; T.Minamoto; Y.Motoo, International journal of oncology41:1347-1357May. 2012
  • Endogenous secretory receptor for advanced glycation end-products inhibits amyloid-β1-42 uptake into mouse brain, T.Sugihara; S.Munesue; Y.Yamamoto; S.Sakurai; N.Akhter; Y.Kitamura; K.Shiba; T.Watanabe; H.Yonekura; Y.Hayashi; J.Hamada; H.Yamamoto, Journal of Alzheimer's disease : JAD28:709-720Feb. 2012
  • Suppression of a neocortical potassium channel activity by intracellular amyloid-β and its rescue with homer1a, K.Yamamoto; Y.Ueta; L.Wang; R.Yamamoto; N.Inoue; K.Inokuchi; A.Aiba; H.Yonekura; N.Kato, The Journal of neuroscience : the official journal of the Society for Neuroscience31:11100-11109Aug. 2011
  • Hypoxia down-regulates sFlt-1 (sVEGFR-1) expression in human microvascular endothelial cells by a mechanism involving mRNA alternative processing, T.Ikeda; L.Sun; N.Tsuruoka; Y.Ishigaki; Y.Yoshitomi; Y.Yoshitake; H.Yonekura, The Biochemical journal.436:399-407Jun. 2011
  • Identification of the COL2A1 mutation in patients with type I Stickler syndrome using RNA from freshly isolated peripheral white blood cells, H.Yaguchi; T.Ikeda; H.Osada; Y.Yoshitake; H.Sasaki; H.Yonekura, Genetic testing and molecular biomarkers.15:231-237Apr. 2011
  • Septic shock is associated with receptor for advanced glycation end products ligation of LPS, Y.Yamamoto; A.Harashima; H.Saito; K.Tsuneyama; S.Munesue; S.Motoyoshi; D.Han; T.Watanabe; M.Asano; S.Takasawa; H.Okamoto; S.Shimura; T.Karasawa; H.Yonekura; H.Yamamoto, Journal of immunology (Baltimore, Md. : 1950)186:3248-32572011
  • Ultraviolet B-induced expression of amphiregulin and growth differentiation factor 15 in human lens epithelial cells, H.Osada; Y.Yoshitake; T.Ikeda; Y.Ishigaki; T.Takata; N.Tomosugi; H.Sasaki; H.Yonekura, Molecular vision17:159-169Jan. 2011
  • Septic shock is associated with receptor for advanced glycation end products ligation of LPS, Y.Yamamoto; A.Harashima; H.Saito; K.Tsuneyama; S.Munesue; S.Motoyoshi; D.Han; T.Watanabe; M.Asano; S.Takasawa; H.Okamoto; S.Shimura; T.Karasawa; H.Yonekura; H.Yamamoto, Journal of immunology (Baltimore, Md. : 1950)186:3248-32572011
  • Regulation of alternative splicing of the receptor for advanced glycation endproducts (RAGE) through G-rich cis-elements and heterogenous nuclear ribonucleoprotein H, K.Ohe; T.Watanabe; S.Harada; S.Munesue; Y.Yamamoto; H.Yonekura; H.Yamamoto, Journal of biochemistry.147:651-659May. 2010
  • Induction of HITS, a newly identified family with sequence similarity 107 protein (FAM107B), in cancer cells by heat shock stimulation, H.Nakajima; Y.Ishigaki; QI-S.Xia; T.Ikeda; Y.Yoshitake; H.Yonekura; T.Nojima; T.Tanaka; H.Umehara; N.Tomosugi; T.Takata; T.Shimasaki; N.Nakaya; I.Sato; K.Kawakami; K.Koizumi; T.Minamoto; Y.Motoo, International journal of oncology37:583-5932010
  • Induction of HITS, a newly identified family with sequence similarity 107 protein (FAM107B), in cancer cells by heat shock stimulation, H.Nakajima; Y.Ishigaki; QI-S.Xia; T.Ikeda; Y.Yoshitake; H.Yonekura; T.Nojima; T.Tanaka; H.Umehara; N.Tomosugi; T.Takata; T.Shimasaki; N.Nakaya; I.Sato; K.Kawakami; K.Koizumi; T.Minamoto; Y.Motoo, International journal of oncology37:583-5932010
  • Solution structure of the variable-type domain of the receptor for advanced glycation end products:new insight into AGE-RAGE interaction, S.Matsumoto; T.Yoshida; H.Murata; S.Harada; N.Fujita; S.Nakamura; Y.Yamamoto; T.Watanabe; H.Yonekura; H.Yamamoto; T.Ohkubo; Y.Kobayashi, Biochemistry.47:12299-12311Nov. 2008
  • Reduced expression of endogenous secretory receptor for advanced glycation endproducts in hippocampal neurons of Alzheimer's disease brains, I.Nozaki; T.Watanabe; M.Kawaguchi; H.Akatsu; K.Tsuneyama; Y.Yamamoto; K.Ohe; H.Yonekura; M.Yamada; H.Yamamoto, Archives of histology and cytology.70:279-290Dec. 2007
  • Promotion by collagen tripeptide of Type I collagen gene expression in human osteoblastic cells and fracture healing of rat femur, N.Tsuruoka; R.Yamato; Y.Sakai; Y.Yoshitake; H.Yonekura, Bioscience, biotechnology, and biochemistry71:2680-2687Nov. 2007
  • De-N-glycosylation or G82S mutation of RAGE sensitizes its interaction with advanced glycation endproducts, M.Osawa; Y.Yamamoto; S.Munesue; N.Murakami; S.Sakurai; T.Watanabe; H.Yonekura; Y.Uchigata; Y.Iwamoto; H.Yamamoto, Biochimica et biophysica acta-molecular and cell biology of lipids1770:1468-1474Oct. 2007
  • Autocrine regulation of angiogenesis, H.Yonekura; N.Tsuruoka; Y.Yoshitake32:8-15Jun. 2007
  • Endogenous secretory receptor for advanced glycation endproducts as a novel prognostic marker in chondrosarcoma, A.Takeuchi; Y.Yamamoto; K.Tsuneyama; C.Cheng; H.Yonekura; T.Watanabe; K.Shimizu; K.Tomita; H.Yamamoto; H.Tsuchiya, Cancer109:2532-2540Jun. 2007
  • Short-chain aldehyde-derived ligands for RAGE and their actions on endothelial cells, Y.Yamamoto; H.Yonekura; T.Watanabe; S.Sakurai; H.Li; A.Harashima; KM.Myint; M.Osawa; A.Takeuchi; M.Takeuchi; H.Yamamoto, Diabetes research and clinical practice.77 (Suppl 1):S30-40Jun. 2007
  • Assaying soluble forms of receptor for advanced glycation end products. (Response), Y.Yamamoto; J.Miura; S.Sakurai; T.Watanabe; H.Yonekura; H.Tamei; H.Matsuki; K.Obata; Y.Uchigata; Y. Iwamoto; H.Koyama; H.Yamamoto, Arteriosclerosis, thrombosis, and vascular biology.27:e33-342007
  • RAGE in diabetic nephropathy, H.Yamamoto; T.Watanabe; Y.Yamamoto; H.Yonekura; S.Munesue; A.Harashima; K.Ooe; S.Hossain; H.Saito; N.Murakami, Current molecular medicine7:752-7572007
  • Assaying soluble forms of receptor for advanced glycation end products. (Response), Y.Yamamoto; J.Miura; S.Sakurai; T.Watanabe; H.Yonekura; H.Tamei; H.Matsuki; K.Obata; Y.Uchigata; Y. Iwamoto; H.Koyama; H.Yamamoto, Arteriosclerosis, thrombosis, and vascular biology.27:e33-342007
  • RAGE in diabetic nephropathy, H.Yamamoto; T.Watanabe; Y.Yamamoto; H.Yonekura; S.Munesue; A.Harashima; K.Ooe; S.Hossain; H.Saito; N.Murakami, Current molecular medicine7:752-7572007
  • Endogenous secretory receptor for advanced glycation endproducts levels are correlated with serum pentosidine and CML in patients with type 1 diabetes., Miura, J; Yamamoto, Y; Osawa, M; Watanabe, T; Yonekura, H; Uchigata, Y; Yamamoto, H; Iwamoto, Y, Arteriosclerosis, thrombosis, and vascular biology.27: 253-254Jan. 2007
  • RAGE control of diabetic nephropathy in a mouse model: effects of RAGE gene disruption and administration of low-molecular weight heparin, K.M.Myint; Y.Yamamoto; T.Doi; I.Kato; A.Harashima; H.Yonekura; T. Watanabe; H.Shinohara; M.Takeuchi; K. Tsuneyama; N.Hashimoto; M.Asano; S.Takasawa; H. Okamoto; H.Yamamoto, Diabetes.55:2510-2522Sep. 2006
  • Development of an ELISA for esRAGE and its application to type 1 diabetic patients., S. Sakurai; Y. Yamamoto; H. Tamei; H. Matsuki; K.-I. Obata; H. Hui; J. Miura; M. Osawa; Y. Uchigata; Y. Iwamoto; T. Watanabe; H. Yonekura; H. Yamamoto, Diabetes research and clinical practice.73:158-165Aug. 2006
  • Receptor for advanced glycation endproducts is involved in impaired angiogenic response in diabetes., T. Shoji; H. Koyama; T. Morioka; S. Tanaka; A. Kizu; K. Motoyama; K. Mori; S. Fukumoto; A. Shioi; N. Shimogaito; M. Takeuchi; Y. Yamamoto; H. Yonekura; H. Yamamoto; Y. Nishizawa, Diabetes.55:2245-2255:100Aug. 2006
  • Identification of mouse ortholog of endogenous secretory receptor for advanced glycation endproducts: structure, function and expression., A. Harashima; Y. Yamamoto; C. Cheng; K. Tsuneyama; K.M. Myint; A. Takeuchi; K. Yoshimura; H. Li; T. Watanabe; S. Takasawa; H. Yonekura; H. Okamoto; H. Yamamoto, The Biochemical journal.396:109-115Mar. 2006


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