SHOJI Hiroki

Researcher Profile & Settings

Research

Overview of research:
Galectins are a family of animal lectin which recognize beta-galactoside-containing carbohydrate moieties. Although, they have been proposed to have roles in a variety of biological processes such as immunity, development, cell differentiation and cancer metastasis, detail of the mechanisms of their actions are remained to be clarified. We are aiming to discover a novel biological concept through our galectin research.

Education

• Osaka University Graduate School Graduate School of Science
• Nagoya University Graduate School Graduate School of Science
• Shizuoka University Faculty of Science

Research Activities

Published Papers

• The supression of DOCK family members by their specific inhibitors induces the cell fusion of human trophoblastic cells, Etsuko Kiyokawa, Hiroki Shoji, Takiko Daikoku, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 529:1173-1179, Sep. 2020
  DOI:10.1016/j.bbrc.2020.06.138
• Leukemia inhibitory factor induces corticotropin-releasing hormone in mouse trophoblast stem cells, He Wang, Tsuyoshi Tsukada, Hiroki Shimada, Hiromi Sakata-Haga, Yasuo Iida, Shitai Zhang, Hiroki Shoji, Toshihisa Hatta, Biochemical and biophysical research communications, 522:81-87, Jan. 2020
• A rapid and nondestructive protocol for whole-mount bone staining of small fish and Xenopus, Sakata-Haga Hiromi, Uchishiba Maimi, Shimada Hiroki, Tsukada Tsuyoshi, Mitani Mayumi, Arikawa Tomohiro, Shoji Hiroki, Hatta Toshihisa, SCIENTIFIC REPORTS, 8:7453, May 2018
  DOI:10.1038/s41598-018-25836-4
• Melanocortins contribute to sequential differentiation and enucleation of human erythroblasts via melanocortin receptors 1, 2 and 5, E.Simamura, T.Arikawa, T.Ikeda, H.Shimada, H.Shoji, H,Masuta, Y.Nakajima, H.Otani, H.Yonekura, T.Hatta, PLoS One, 10:e0123232-e0123232, 2015
  DOI:10.1371/journal.pone.0123232
• Crystal structure of a Xenopus laevis skin proto-type galectin, close to but distinct from galectin-1, (Y.Nonaka), T.Ogawa, H.Yoshida, H.Shoji, N.Nishi, S.Kamitori, T.Nakamura, Glycobiology, 25:792-803, 2015
  DOI:10.1093/glycob/cwv020
• Effects of melanocortins on fetal development, E.Simamura, H.Shimada, H.Shoji, H.Otani, T.Hatta, Congenital anomalies, 51:47-54, 2011
• Tumor cells secrete galectin-1 to enhance endothelial cell activity., (Thijssen VL), Barkan B, H.Shoji, Aries IM, Mathieu V, Deltour L, Hackeng TM, Kiss R, Kloog Y, Poirier F, Griffioen AW, Cancer research, 70(15):6216-24, Aug. 2010
• Expression pattern and role of Galectin1 during early mouse, H.Shoji, L.Deltour, T.Nakamura, S.Tajbakhsh, F.Poirier, Development, growth & differentiation, 51:607？615, Jun. 2009
• Induction of cell adhesion by galectin-8 and its target molecules in Jurkat T cells., (H.Yamamoto), N.Nishi, H.Shoji, A.Ito, LH.Lu, M.Hirashima, T.Nakamura, Journal of biochemistry., 143:311-324, 2008
• Involvement of galectin-9 in guinea pig allergic airway inflammation, International archives of allergy and immunology., 143 / suppl. 1 , 95-105, 2007
• Characterization of Galectin-9-Induced Death of Jurkat T Cells., Journal of biochemistry., 141: 157-172, 2007
• Comparative Biochemistry of the Galectin Families, WEB site, Glycoforum, Glycoword, Comparative glycomics and life evolution, 2005
• Characterization of the Xenopus galectin family. Three structurally different types as in mammals and regulated expression during embryogenesis, The Journal of biological chemistry., 278 / 14 , 12285-12293, 2003
• Exposure to Maternal Immune Activation Causes Congenital Unfolded Protein Response Defects and Increases the Susceptibility to Postnatal Inflammatory Stimulation in Offspring, Yo Shimizu, Tsuyoshi Tsukada, Hiromi Sakata-Haga, Daisuke Sakai, Hiroki Shoji, Yutaka Saikawa, Toshihisa Hatta, Journal of Inflammation Research, 14:355-365, Feb. 2021
  DOI:10.2147/JIR.S294238