NISHINO Yoshikazu

Researcher Profile & Settings

Research

Overview of research:
I mainly work with epidemiology to investigate risk factors of cancer and to evaluate effectiveness and accuracy of cancer screening program. Especially, I investigate area differences of cancer incidence and mortality and their relevant factors.

Education

• Tohoku University Graduate School of Medicine

Degree

• Ph.D in Medicine

Research Activities

Published Papers

• Dioxin exposure and sexual dimorphism of gaze behavior in prepubertal Vietnamese children living in Da Nang, a hot spot for dioxin contamination, Thao Ngoc Pham, Muneko Nishijo, Tai The Pham, Hoa Thi Vu, Nghi Ngoc Tran, Anh Hai Tran, Quyet Do, Tomoya Takiguchi, Yoshikazu Nishino, Hisao Nishijo, Science of the Total Environment, 749:141083, Dec. 2020
• Combination effects of a fatty diet and exercise on the depressive state and cardioprotection in apolipoprotein E knockout mice with a change in RCAN1 expression, Wang Shuo, Haicong Li, Nishijo Muneko, Nishino Yoshikazu, Nobuo Kato, Yuji Kasamaki, Tadashi Ueda, Tsugiyasu Kanda, Journal of International Medical Research, 48:300060520964016, Nov. 2020
• Associations of Japanese food intake with survival of stomach and colorectal cancer: A prospective patient cohort study, (Yuko Minami), Seiki Kanemura, Tomoyuki Oikawa, Shinichi Suzuki, Yasuhiro Hasegawa, Yoshikazu Nishino, Tsuneaki Fujiya, Koh Miura, Cancer Science, 111:2558-2569, Jul. 2020
  DOI:10.1111/cas.14459
• Effects of perinatal dioxin exposure on learning abilities of 8-year-old children in Vietnam, Tai Pham The, Thao Pham Ngoc, Tong Hoang Van, Muneko Nishijo, Nghi Tran Ngoc, Hoa Vu Thi, Luong Hoang Van, Anh Tran Hai, Yoshikazu Nishino, Hisao Nishijo, International Journal of Hygiene and Environmental Health, 223:132-141, Jan. 2020
  DOI:10.1016/j.ijheh.2019.09.010
• Alcohol consumption and survival after breast cancer diagnosis in Japanese women:A prospective patient cohort study, (Yuko Minami), Seiki Kanemura, Masaaki Kawai, Yoshikazu Nishino, Hiroshi Tada, Minoru Miyashita, Takanori Ishida, Yoichiro Kakugawa, PLoS One, 14:e0224797, Nov. 2019
• Reproductive history and breast cancer survival: a prospective patient cohort study in Japan, (Yuko Minami), Yoshikazu Nishino, Masaaki Kawai, Hiroshi Tada, Seiki Kanemura, Minoru Miyashita, Takanori Ishida, Yoichiro Kakugawa, Breast cancer (Tokyo, Japan), 26:687-702, Nov. 2019
  DOI:10.1007/s12282-019-00972-5
• Trends in Small-Cell Lung Cancer Survival in 1993-2006 Based on Population-Based Cancer Registry Data in Japan, (Isao Oze), Hidemi Ito, Yoshikazu Nishino, Masakazu Hattori, Tomio Nakayama, Isao Miyashiro, Keitaro Matsuo, Yuri Ito, Journal of epidemiology, 29:347-353, Sep. 2019
  DOI:10.2188/jea.JE20180112
• Perinatal dioxin exposure and neurodevelopment of 2-year-old Vietnamese children in the most contaminated area from Agent Orange in Vietnam, Ngoc Thao Pham, Muneko Nishijo, The Tai Pham, Ngoc Nghi Tran, Van Quan Le, Hai Anh Tran, Huy Anh Vu Phan, Yoshikazu Nishino, Hisao Nishijo, The Science of the total environment, 678:217-226, Aug. 2019
  DOI:10.1016/j.scitotenv.2019.04.425
• Adverse effects of maternal dioxin exposure on fetal brain development before birth assessed by neonatal electroencephalography (EEG) leading to poor neurodevelopment; a 2-year follow-up study, (GiangThi Thuy Nghiem), Muneko Nishijo, Thao Ngoc Pham, Mika Ito, Tai The Pham, Anh Hai Tran, Hiroshi Nishimaru, Yoshikazu Nishino, Hisao Nishijo, The Science of the total environment, 667:718-729, Jun. 2019
  DOI:10.1016/j.scitotenv.2019.02.395
• Association between Family History of Cancer and Lung Cancer Risk among Japanese Men and Women, (Kaoru Yoshida), Yoko Takizawa, Yoshikazu Nishino, Satomi Takahashi, Seiki Kanemura, Junko Omori, Hajime Kurosawa, Makoto Maemondo, Yuko Minami, The Tohoku journal of experimental medicine, 247:99-110, Feb. 2019
  DOI:10.1620/tjem.247.99
• Recent Improvement in the Long-term Survival of Breast Cancer Patients by Age and Stage in Japan, (Akiyo.Yoshimura), Hidemi.Ito, Yoshikazu.Nishino, Masakazu.Hattori, Tomohiro.Matsuda, Isao.Miyashiro, Tomio.Nakayama, Hiroji.Iwata, Keitaro.Matsuo, Hideo.Tanaka, Yuri.Ito, JOURNAL OF EPIDEMIOLOGY, 28:420-427, Oct. 2018
  DOI:10.2188/jea.JE20170103
• Associations of cigarette smoking and alcohol drinking with stomach cancer survival: A prospective patient cohort study in Japan, (Yuko.Minami), Seiki.Kanemura, Tomoyuki.Oikawa, Shinichi.Suzuki, Yasuhiro.Hasegawa, Koh.Miura, Yoshikazu.Nishino, Yoichiro.Kakugawa, Tsuneaki.Fujiya, INTERNATIONAL JOURNAL OF CANCER, 143:1072-1085, Sep. 2018
  DOI:10.1002/ijc.31408
• Sex-specific effects of perinatal dioxin exposure on eating behavior in 3-year-old Vietnamese children, Anh Thi Nguyet Nguyen, Muneko.Nishijo, Tai The Pham, Nghi Ngoc Tran, Anh Hai Tran, Luong Van Hoang, Hitomi.Boda, Yuko.Morikawa, Yoshikazu.Nishino, Hisao.Nishijo, BMC PEDIATRICS, 18:213, Jul. 2018
  DOI:10.1186/s12887-018-1171-2
• Improvement in 5-Year Relative Survival in Cancer of the Corpus Uteri From 1993-2000 to 2001-2006 in Japan, (Shusaku.Inoue), Satoyo.Hosono, Hidemi.Ito, Isao.Oze, Yoshikazu.Nishino, Masakazu.Hattori, Tomohiro.Matsuda, Isao.Miyashiro, Tomio.Nakayama, Mika.Mizuno, Keitaro.Matsuo, Kiyoko.Kato, Hideo.Tanaka, Yuri.Ito, the J-CANSIS Res Grp, JOURNAL OF EPIDEMIOLOGY, 28:75-80, Feb. 2018
  DOI:10.2188/jea.JE20170008
• Prenatal dioxin exposure estimated from dioxins in breast milk and sex hormone levels in umbilical cord blood in Vietnamese newborn infants., Boda Hitomi;Nghi Tran Ngoc;Nishijo Muneko;Thao Pham Ngoc;Tai Pham The;Van Luong Hoang;Anh Tran Hai;Morikawa Yuko;Nishino Yoshikazu;Nishijo Hisao, The Science of the total environment, 615:1312, Feb. 2018
• Alcohol Consumption and Breast Cancer Risk According to Hormone Receptor Status in Japanese Women: A Case-Control Study, (Yoko.Takizawa), Masaaki.Kawai, Yoichiro.Kakugawa, Yoshikazu.Nishino, Noriaki.Ohuchi, Yuko.Minami, TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, 244:63-73, Jan. 2018
  DOI:10.1620/tjem.244.63
• Association between coffee consumption and all-sites cancer incidence and mortality, (J.Sado), T.Kitamura, Y.Kitamura, T.Sobue, Y.Nishino, H.Tanaka, T.Nakayama, I.Tsuji, H.Ito, T.Suzuki, K.Katanoda, S.Tominaga, Three-Prefecture Cohort Study Group, Cancer Science, 108:2079-2087, Oct. 2017
  DOI:10.1111/cas.13328
• Changes in trends in colorectal cancer incidence rate by anatomic site between 1978 and 2004 in Japan., (H.Nakagawa), H.Ito, S.Hosono, I.Oze, H.Mikami, M.Hattori, Y.Nishino, H.Sugiyama, K.Nakata, H.Tanaka, European journal of cancer prevention, 26:269-276, Jul. 2017
  DOI:10.1097/CEJ.0000000000000255
• Gender-specific impact of cadmium exposure on bone metabolism in older people living in a cadmium-polluted area in Thailand, Muneko.Nishijo, Kowit.Nambunmee, Dhitiwass.Suvagandha, Witaya.Swaddiwudhipong, Werawan.Ruangyuttikarn, Yoshikazu.Nishino, International Journal of Envitronmental Research and Publich Health, 14:401, Apr. 2017
  DOI:10.3390/ijerph14040401
• The association between coffee consumption and bladder cancer incidence in a pooled analysis of the Miyagi Cohort Study and Ohsaki Cohort Study., (K.Sugiyama), Y.Sugawara, Y.Tomata, Y.Nishino, A.Fukao, I.Tsuji, European journal of cancer prevention, 26:125-130, Mar. 2017
  DOI:10.1097/CEJ.0000000000000226.
• Associations of obesity and physical activity with serum and intratumoral sex steroid hormone levels among postmenopausal women with breast cancer:analysis of paired serum and tumor tissue samples, (Yoichiro.Kakugawa), Hiroshi.Tada, Masaaki.Kawai, Takashi.Suzuki, Yoshikazu.Nishino, Seiki.Kanemura, Takanori.Ishida, Noriaki.Ohuchi, Yuko.Minami, BREAST CANCER RESEARCH AND TREATMENT, 162:115-125, Feb. 2017
• Rationale, design, and profile of the Three-Prefecture Cohort in Japan: A 15-year follow-up, (Junya.Sado), Tetsuhisa.Kitamura, Yuri.Kitamura, Ling.Zha, Rong.Liu, Tomotaka.Sobue, Yoshikazu.Nishino, Hideo.Tanaka, Tomio.Nakayama, Ichiro.Tsuji, Hidemi.Ito, Takaichiro.Suzuki, Kota.Katanoda, Suketami.Tominaga, for the Three-Prefecture Cohort Studu Group, Journal of Epidemiology, 27:193-199, Jan. 2017
• Challenges in breast and cervical cancer control in Japan, (Sauvaget Catherine), Y.Nishino, R.Konno, T.Tase, T.Morimoto, S.Hisamichi, The Lancet Oncology, 17:e305-e312, Jul. 2016
  DOI:10.1016/S1470-2045(16)30121-8
• Impacts of Perinatal Dioxin Exposure on Motor Coordination and Higher Cognitive Development in Vietnamese Preschool Children: A Five-Year Follow-Up., Tran Nghi Ngoc, Pham Tai The, K.Ozawa, M.Nishijo, Nguyen Anh Thi Nguyet; Tran Tuong Quy, Hoang Luong Van, Tran Anh Hai, Phan Vu Huy Anh, A.Nakai, Y.Nishino, H.Nishijo, PLOS ONE, 11:e0147655-e1047655, Jan. 2016
  DOI:10.1371/journal.pone.0147655
• Effects of Perinatal Dioxin Exposure on Physical Growth and Neurodevelopment of Infants and Children, M.Nishijo, Tran Ngoc Nghi, Y.Morikawa, M.Sakurai, S.Nagasawa, Y. Nishino, Journal of kanazawa medhical university, 40:78-83, Dec. 2015
• Effects of a Lower Lipid Diet and Exercise on Cognitive Disturbances with the Induction of Calcineurin 1 and Brain-derived Neurotrophic Factor Expressions in the Hippocampi of Obese Apolipoprotein E Knockout Mice, Shuo Wang, Haicong Li, Mineko Nishijo, Yoshikazu Nishino, Nobuo Kato, Yuji Kasamaki, Tadashi Ueda, Tsugiyasu Kanda, JMA Journal, 4:409-414, 2021
  DOI:10.31662/jmaj.2021-0082
• Effects of perinatal dioxin exposure on neonatal electroencephalography (EEG) activity of the quiet sleep stage in the most contaminated area from Agent Orange in Vietnam., Ngoc Thao Pham, Muneko Nishijo, Thi Thuy Giang Nghiem, The Tai Pham, Ngoc Nghi Tran, Van Quan Le, Thi Hoa Vu, Hai Anh Tran, Huy Anh Vu Phan, Quyet Do, Tomoya Takiguchi, Yoshikazu Nishino, Hisao Nishijo, International journal of hygiene and environmental health, 232:113661, 2021
  DOI:10.1016/j.ijheh.2020.113661
• Nutritional Intervention with Dried Bonito Broth for the Amelioration of Aggressive Behaviors in Children with Prenatal Exposure to Dioxins in Vietnam: A Pilot Study., Muneko Nishijo, Tai The Pham, Ngoc Thao Pham, Hai Thai Thu Duong, Ngoc Nghi Tran, Takashi Kondoh, Yoshikazu Nishino, Hiroshi Nishimaru, Quyet Ba Do, Hisao Nishijo, Nutrients, 13:1455, 2021
  DOI:10.3390/nu13051455
• Effects of perinatal dioxin exposure on mirror neuron activity in 9-year-old children living in a hot spot of dioxin contamination in Vietnam., Hoa Thi Vu, Muneko Nishijo, Thao Ngoc Pham, Tai Pham-The, Luong Van Hoanh, Anh Hai Tran, Nghi Ngoc Tran, Yoshikazu Nishino, Quyet Do, Hisao Nishijo, Neuropsychologia, 161:108001, 2021
  DOI:10.1016/j.neuropsychologia.2021.108001
• Alterations in Regional Brain Regional Volume Associated with Dioxin Exposure in Men Living in the Most Dioxin-Contaminated Area in Vietnam: Magnetic Resonance Imaging (MRI) Analysis Using Voxel-Based Morphometry (VBM)., Hoa Thi Vu, Thao Ngoc Pham, Takashi Yokawa, Muneko Nishijo, Tai Pham The, Quyet Do, Yoshikazu Nishino, Hisao Nishijo, Toxics, 9:353, 2021
  DOI:10.3390/toxics9120353
• Multi-institutional survey of cancer disparities in disabled patients in the region of northwestern Japan., (Shigeki Sato), Azusa Tanimoto, Naohiro Yanagimura, Chiaki Suzuki, Yohei Takumi, Akihiro Nishiyama, Kaname Yamashita, Shinji Takeuchi, Koushiro Ohtsubo, Tomoe Makino, Yoshio Yoshida, Yasuo Hirono, Ryuji Hayashi, Tomonobu Koizumi, Yozo Nakazawa, Ken-Ichi Ito, Yoshiharu Motoo, Hidetaka Uramoto, Mitsutoshi Nakada, Yoshikazu Nishino, Seiji Yano, International journal of clinical oncology, 26:1009-1014, 2021
  DOI:10.1007/s10147-021-01890-3
• Multi-institutional survey of malignant pleural mesothelioma patients in the Hokushin region., Uramoto H, Takiguchi T, (Koizumi T), (Tanimoto A), (Hayashi R), (Nakazawa Y), (Ito KI), (Nakada M), (Hirono Y), Nishino Y, (Yano S), Jounal of Cancer Research and Clinical Oncology, 148:1153-1158, May 2022
  DOI:doi: 10.1007/s00432-021-03699-z. Epub 2021 Jun 29. PMID: 34185142.
• Multi-institutional survey of thymic carcinoma patients in Hokushin region., Uramoto H, Takiguchi T, (Koizumi T), (Tanimoto A), (Hayashi R), (Nakazawa Y), (Ito KI), (Nakada M), (Hirono Y), Nishino Y, (Yano S)., Jounal of cancer resach and clinical oncology, 148:419-424, Feb. 2022
  DOI:doi: 10.1007/s00432-021-03620-8.
• Effect of Perinatal Dioxin Exposure Originating from Agent Orange on Gaze Behavior in 3-Year-Old Children Living in the Most Dioxin-Contaminated Areas in Vietnam, Thao Ngoc Pham, Muneko Nishijo, Tai Pham-The, Nghi Ngoc Tran, Hoa Thi Vu, Anh Hai Tran, Tien Viet Tran, Yoshikazu Nishino, Hisao Nishijo, Toxics, 10:150, Mar. 2022
  DOI:doi: 10.3390/toxics10040150
• Perinatal Dioxin Exposure and Attention Deficit Hyperactivity Disorder (ADHD) Symptoms in Children Living in a Dioxin Contamination Hotspot in Vietnam, (Tai Pham-The), Muneko Nishijo, Thao Ngoc Pham, Hoa Thi Vu, Nghi Ngoc Tran, Anh Hai Tran, Luong Van Hoang, Quyet Do, Yoshikazu Nishino, Hisao Nishijo, Toxics, 10:212, Apr. 2022
  DOI:doi: 10.3390/toxics10050212
• Cancer among children, adolescents and young adults in the Hokushin region, Japan, between 2010 and 2015, (Eri Okura), Yoshikazu Nishino, Kazuo Sakashita, Azusa Tanimoto, Ryuji Hayashi, Yoshio Yoshida, Mitsutoshi Nakada, Tomonobu Koizumi, Seiji Yano, Yozo Nakazawa, Japanese Journal of Clinical Oncology, 52:86-95, Jan. 2022
  DOI:doi: 10.1093/jjco/hyab174
• Associations of cigarette smoking, alcohol drinking and body mass index with survival after colorectal cancer diagnosis by anatomic subsite: a prospective patient cohort study in Japan, (Yuko Minami), Seiki Kanemura, Jun Kusaka, Makoto Kinouchi, Shinichi Suzuki, Yoshikazu Nishino, Koh Miura, Japanese Journal of Clinical Oncology, 52:1375-1388, Dec. 2022
  DOI:10.1093/jjco/hyac140

Books etc

• Chapter4 Deaths from Cancer
  The Atlas of Health Inequalities in Japan (Tomoki Nakaya, Yuri Ito)
  Yuri Ito, Yoshikazu Nishino, Seiki Kanemura, Tomoki Nakaya
  Springer  Oct. 2019