TAKATSUJI-SAITO Hidehito

FacultyDepartment of Biochemistry Ⅱ
PositionAssistant Professor

Researcher Profile & Settings

Degree

  • Ph.D in Medicine

Research Activities

Published Papers

  • EAPC2 acts as a negative regulator in Matrigel-driven tubulogenesis of human microvascular endothelial cells, Takayuki Ikeda, Yoshino Yoshitake, Yasuo Yoshitomi, Hidehito Saito-Takatsuji, Yasuhito Ishigaki, Hideto Yonekura, Scientific reports11:19453Sep. 2021
  • Role of Arginine Methylation in Alternative Polyadenylation of VEGFR-1 (Flt-1) pre-mRNA, Takayuki Ikeda, Hidehito Saito-Takatsuji, Yasuo Yoshitomi, Hideto Yonekura, International Journal of Molecular Sciences21:6460Sep. 2020
  • CX3CR1-CD8+ T cells are critical in antitumor efficacy but functionally suppressed in the tumor microenvironment, (Takayoshi Yamauchi), Toshifumi Hoki, Takaaki Oba, Hidehito Saito, Kristopher Attwood, Michael S Sabel, Alfred E Chang, Kunle Odunsi, Fumito Ito, JCI insight5:e133920Apr. 2020
  • Ultraviolet B-induced Otx2 expression in lens epithelial cells promotes epithelial-mesenchymal transition, Yoshitomi Y, Osada H, Satake H, Kojima M, Saito-Takatsuji H, Ikeda T, Yoshitake Y, Ishigaki Y, Kubo E, Sasaki H, Yonekura H, Biology Open8:bio035691Feb. 2019
  • JunB regulates angiogenesis and neurovascular parallel alignment in mouse embryonic skin, Y.Yoshitomi,T.Ikeda,H.Saito,Y.Yoshitake,Y.Ishigaki,T.Hatta,N.Kato,H.Yonekura, Jonal of Cell Science130:916-926Jan. 2017
  • Generation of induced pluripotent stem cells from human melanoma tumor-infiltrating lymphocytes, H.Saito, K.Iwabuchi, N.Fusaki, F. Ito, Journal of Visualized Experiments117:e54375-e54375Nov. 2016
  • Adoptive transfer of CD8+ T cells generated from induced pluripotent stem cells triggers regressions of large tumors along with immunological memory, H.Saito, K.Okita, AE.Chang, F.Ito, Cancer Research76:3473-3483Jun. 2016
  • Reprogramming of melanoma tumor-infiltrating lymphocytes to induced pluripotent stem cells., H.Saito, K.Okita, N.Fusaki, MS.Sabel, AE.Chang, F.Ito, Stem Cells International2016:8394960-**Jan. 2016
  • Regulation of soluble Flt-1(VEGFR-1) production by hnRNP D and protein arginine methylation, T.Ikeda, Y.Yoshitomi, H.Saito, T.Shimasaki, H.Yamaya, T.Kobata, Y.Ishigaki, N.Tomosugi, Y.Yoshitake, H.Yonekura, Molecular and Cellular Biochemistry413:155-1642016
  • cAMP ameliorates inflammation by modulation of macrophage receptor for advanced glycation end-products., (S.Motoyoshi), Y.Yamamoto, S.Munesue, H.Igawa, A.Harashima,H.Saito, D.Han, T.Watanabe, H.Sato, H.Yamamoto, Biochemical Journal463:75-82Oct. 2014
  • Sivelestat sodium hydrate inhibits neutrophil migration to the vessel wall and suppresses hepatic ischemia-reperfusion injury., (S.Sakai), H.Tajima, T.Miyashita, S.Nakanuma, I.Makino, H.Hayashi, H.Nakagawara, H.Kitagawa, S.Fushida, T.Fujimura, H.Saito, S.Munesue, Y.Yamamoto, T.Ohta, Digestive Diseases and Sciences59:787-794Apr. 2014
  • Low-molecular weight fractions of japanese soy sauce act as a rage antagonist via inhibition of rage trafficking to lipid rafts., (S.Munesue), Y.Yamamoto, R.Urushihara, K.Inomata, H.Saito, S.Motoyoshi, T.Watanabe, H.Yonekura, H.Yamamoto, Food & Function4:1835-1842Dec. 2013
  • Induction of receptor for advanced glycation end products by insufficient leptin action triggers pancreatic beta-cell failure in type 2 diabetes., (D.Han), Y.Yamamoto, S.Munesue, S.Motoyoshi, H.Saito, MT.Win, T.Watanabe, K.Tsuneyama, H.Yamamoto, Genes to Cells18:302-314Apr. 2013
  • Diabetes alters subsets of endothelial progenitor cells that reside in blood, bone marrow, and spleen., H.Saito, Y.Yamamoto, H.Yamamoto, American Journal of Physiology - Cell Physiology302:C892-C901May 2012
  • Regulation of rage for attenuating progression of diabetic vascular complications., (MT.Win), Y.Yamamoto, S.Munesue, H.Saito, D.Han, S.Motoyoshi, T.Kamal, T.Ohara, T.Watanabe, H.Yamamoto., Journal of Diabetes Research2012:8-8Jan. 2012
  • Septic shock is associated with receptor for advanced glycation end products ligation of lps., (Y.Yamamoto), A.Harashima, H.Saito, K.Tsuneyama, S.Munesue, S.Motoyoshi, D.Han, T.Watanabe, M.Asano, S.Takasawa, H.Okamoto, S.Shimura, T.Karasawa, H.Yonekura, H.Yamamoto, Journal of Immunology186:3248-3257Mar. 2011
  • Rage in diabetic nephropathy., (H.Yamamoto), T.Watanabe, Y.Yamamoto, H.Yonekura, S.Munesue, A.Harashima, K.Ooe, S.Hossain, H.Saito, N.Murakami, Current Molecular Medicine7:752-757Dec. 2007
  • Protective Effects of Collagen Tripeptides in Human Aortic Endothelial Cells by Restoring ROS-Induced Transcriptional Repression, Hidehito Saito-Takatsuji, Yasuo Yoshitomi, Yasuhito Ishigaki, Shoko Yamamoto, Noriaki Numata, Yasuo Sakai, Masayoshi Takeuchi, Naohisa Tomosugi, Shogo Katuda, hideto Yonekura, Takayuki Ikeda, Nutrients13:2226Jun. 2021
  • Emerging Role of AP-1 Transcription Factor JunB in Angiogenesis and Vascular Development, Yasuo Yoshitomi, Takayuki Ikeda, Hidehito Saito-Takatsuji, Hideto Yonekura, International Journal of Molecular Sciences22:2804Mar. 2021